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  1. 43441

    Long COVID in people with mental health disorders: a scoping review by Catharina Münte, Manuela Glattacker, Saskia Müller, Andrea E. Zülke, Martin Heinze, Steffi G. Riedel-Heller, Dawid Pieper, Christian Jacke, Stefanie Deckert, Anne Neumann

    Published 2025-07-01
    “…Little is known about individuals with pre-existing mental health conditions experiencing Long COVID. This scoping review aims to provide an overview of these individuals, focusing on: 1) the course of mental disorders, 2) care needs, 3) utilization of healthcare services, and 4) psychosocial aspects, as outlined by the International Classification of Functioning (ICF). …”
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  2. 43442

    Short light/dark cycles favour photosynthetic efficiency and growth in grapevines by Mariana Gómez Tournier, Laurent Torregrosa, Jana Kändler, Angélique Christophe, Romain Boulord, Anna Medici, Anne Pellegrino

    Published 2025-07-01
    “…Light and temperature in greenhouses or growth chambers are major regulatory factors in plant functioning, which can be easily modulated. Shortening the photo-/nycti-periods, compared to the standard cycle (12 h light/12 h dark), has been shown to enhance the photosynthetic activity and growth in annual crops, but its effect on perennial crops such as grapevines remains unexplored. …”
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  3. 43443

    Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis by Wenfei Qin, Nuoming Yin, Binqiang Xu, Qixiang Mei, Yang Fu, Junjie Fan, Yingying Lu, Guangqiang Wang, Lianzhong Ai, Zhanjun Lu, Yue Zeng, Chunlan Huang

    Published 2025-07-01
    “…Abstract Background Faecalibacterium prausnitzii plays a crucial role in ulcerative colitis (UC) remission, but its action mechanism is unknown. Here, we aimed to explore the potential mechanisms focusing on the interaction of F. prausnitzii with host immune response and its potential modulation on gut microbiome. …”
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  4. 43444

    Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study by Alissa Behn, Saskia Brendle, Saskia Brendle, Marianne Ehrnsperger, Marianne Ehrnsperger, Magdalena Zborilova, Thomas M. Grupp, Thomas M. Grupp, Joachim Grifka, Joachim Grifka, Nicole Schäfer, Susanne Grässel, Susanne Grässel

    Published 2025-02-01
    “…Luminex multiplex ELISA were performed with lipoaspirates and cell supernatants alongside functional assays evaluating cell migration, proliferation, metabolic activity, and senescence.ResultsA total of 62 cytokines, chemokines, growth factors, neuropeptides, matrix-degrading enzymes, and complement components were identified in lipoaspirates. …”
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  5. 43445

    Mobile genetic elements mediating antimicrobial resistance drive the evolutionary process of Clostridioides difficile ST37/RT017 by Tao Lv, Xiajing Bi, Lisi Zheng, Yuhong Zhao, Yizheng Zhou, Tao Wu, Ping Shen, Danhua Zhu, Shiyao Chen, Yunbo Chen

    Published 2025-07-01
    “…Furthermore, other functional genes, especially srtB, were notable in C. difficile ST37/RT017, which gradually acquired resistance genes from VL I to VL II and VL III. …”
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  6. 43446

    Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury by Qin Dong, Pengyu Chen, Wenqiao Qiu, Zhijun Yang, Yanteng Li, Yuhui Zhou, Lili Guo, Dan Zou, Ruxiang Xu, Mou Gao

    Published 2025-01-01
    “…We previously reported that induced neural stem cells (iNSCs) can block the effects of CXCL12/CXCR4 signaling on NF-κB activation in activated microglia by CXCR4 overexpression. Here we aim to uncover the mechanism of CXCR4 upregulation in iNSCs. …”
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  7. 43447
  8. 43448

    Artificial Intelligence in Medical Care – Patients' Perceptions on Caregiving Relationships and Ethics: A Qualitative Study by Jana Gundlack, Sarah Negash, Carolin Thiel, Charlotte Buch, Jan Schildmann, Susanne Unverzagt, Rafael Mikolajczyk, Thomas Frese, PEAK consortium

    Published 2025-04-01
    “…Perceived main advantages of AI were its efficient and flawless functioning, its ability to process and provide large data volume, and increased patient safety. …”
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  9. 43449
  10. 43450

    Does Robotic‐Assisted Total Knee Arthroplasty Improve Outcomes of Adult Osteoarthritis Patients—A Systematic Review and Trial Sequential Meta‐Analysis by Han‐Yang Yue, Guo‐Qiang Ding, Hua‐Xin Li, Jun Zeng, Xiao‐Dan Jiang, Zong‐Dong Zhu, Hua Jiang

    Published 2025-06-01
    “…However, the comparative efficacy and safety of rTKA versus cTKA remain unclear due to inconsistent findings in existing studies. This study aims to systematically review and compare the efficacy and safety of rTKA and cTKA in patients with KOA. …”
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  11. 43451

    Lyophilized human platelet lysate: manufacturing, quality control, and application by Kerstin Wendland, Kerstin Wendland, Lea Koblin, Lea Koblin, Dirk Stobbe, Anna Dahms, Anna Dahms, Debora Singer, Debora Singer, Sander Bekeschus, Sander Bekeschus, Jan Wesche, Janosch Schoon, Konstanze Aurich

    Published 2025-01-01
    “…The comparison of L-HPL with HPL did not reveal any relevant differences regarding quality control parameters of routine testing, growth factor concentrations and hMSC functionality, demonstrating the suitability of L-HPL as a cell culture supplement. …”
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  12. 43452

    The First Experience of Using the Developed Modified Allogenic Bone Grafts in the Surgical Treatment of Patients With Severe Fractures of the Surgical Neck of the Humerus by A. Y. Vaza, A. M. Fain, N. V. Borovkova, I. E. Galankina, M. S. Makarov, O. A. Zabavskaya, R. S. Titov, L. N. Ziminа, G. A. Nefedova, V. B. Bondarev, A. S. Mironov, I. N. Ponomarev

    Published 2021-04-01
    “…However, the incidence of unsatisfactory functional results after surgery remains high.AIM OF STUDY To develop allogeneic graft to strengthen the proximal humerus in the osteosynthesis of a comminuted fracture with a lack of bone tissue which has osteoconductive properties and capable of being a carrier of biologically active substances.MATERIAl AND METHODS The head, neck and portion of diaphysis of a fibula of a cadaver were used for a graft. …”
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  13. 43453

    Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma by Jipin Li, Jipin Li, Tao Yong, Tao Yong, Yali Chen, Tingyu Zeng, Kaifeng Zhang, Shuping Wang, Youcheng Zhang

    Published 2025-04-01
    “…Protein-protein interactions between PCNA and PARP1 were validated through co-immunoprecipitation and functional assays. The sensitivity of HCC cells to the PARP1 inhibitor Olaparib was evaluated under PCNA inhibition. …”
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  14. 43454

    In-vitro and in-vivo assessment of biocompatibility and efficacy of ostrich eggshell membrane combined with platelet-rich plasma in Achilles tendon regeneration by Omid Koohi-Hosseinabadi, Reza Shahriarirad, Amireza Dehghanian, Laleh Amini, Sajjad Barzegar, Afrooz Daneshparvar, Omid Alavi, Seyedeh-Parvin Khazraei, Saba Hosseini, Ali Arabi Monfared, Roya Khorram, Nader Tanideh, Soheil Ashkani-Esfahani

    Published 2025-01-01
    “…Despite advancements in tendon injury repair techniques, outcomes remain suboptimal due to inferior tissue quality and functionality. Tissue engineering offers a promising avenue for tendon regeneration, with biocompatible scaffolds playing a crucial role. …”
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  15. 43455

    hucMSC-derived exosomes targeting macrophage polarization attenuate systemic inflammation in T1DM via INS/SOD1 delivery by Xin Chen, Hong An, Yongbiao Du, Hao Zhong, Fangfang Zhang, Xiaomei Zeng, Fen Lv, Zhihua Tian, Zaixue Jiang, Qi Peng, Zengbao Li, Siping Li, Baimao Zhong, Xiaomei Lu, Yinghua Zhu

    Published 2025-07-01
    “…Proteomic profiling, pharmacological inhibition, and functional assays were employed to identify critical exosomal components. …”
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  16. 43456

    A novel single-port robotic system in urology: A prospective multicenter single-arm clinical trial evaluating feasibility and efficacy of first 50 cases by Zheng Wang, Chao Zhang, Taile Jing, Yong Wei, Chengwu Xiao, Yang Wang, Yu Fang, Xiaofeng Wu, Shouyan Tang, Hong Xu, Yi Liu, Bo Yang, Shuo Wang, Bin Xu, Qingyi Zhu, Dan Xia, Zhenjie Wu, Xiaofeng Gao, Linhui Wang

    Published 2025-04-01
    “…Objective: This study aimed to assess the feasibility and safety of the SHURUI single-port robotic surgical system for a range of major urological surgeries. …”
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  17. 43457

    <i>Heortia vitessoides</i> Infests <i>Aquilaria sinensis</i>: A Systematic Review of Climate Drivers, Management Strategies, and Molecular Mechanisms by Zongyu Yin, Yingying Chen, Huanrong Xue, Xiaofei Li, Baocai Li, Jiaming Liang, Yongjin Zhu, Keyu Long, Jinming Yang, Jiao Pang, Kaixiang Li, Shaoming Ye

    Published 2025-07-01
    “…Current research has preliminarily revealed its biological traits and gene functions. However, significant gaps persist in integrating climate adaptation mechanisms, control technologies, and host interaction networks across disciplines. …”
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  18. 43458

    Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans by Muhammad Sadiq Khan, Ayesha Akter, Ismail Khan, Luis Carlos Ramos Aguila, Lina Akter, Mengmeng Yang, Xu Li, Yuelin Li

    Published 2025-03-01
    “…The outcomes also provide valuable insights for future sustainability strategies aimed at enhancing greenness resilience in the central and southeast regions of the Sundarbans, ensuring the long-term preservation of the natural mangrove landscape.…”
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  19. 43459

    Genetic Analysis and Fine Mapping of QTLs for Stigma Exsertion Rate in Rice by Hanyuan Yang, Yin Zhou, Pingbo Li, Enyu Liu, Ping Sun, Yiting Ao, Rongjia Liu, Haozhou Gao, Zherui Xu, Ping Yang, Xinyue Wang, Guanjun Gao, Qinglu Zhang, Lizhong Xiong, Yuqing He

    Published 2024-12-01
    “…A combination of sequencing, expression and haplotype analysis revealed that a single nucleotide variation (T to C) in the 5’UTR region of LOC_Os01g72020 (OsBOP1) was likely to be the functional variation for qSE1. Collectively, our work has laid a foundation for cloning the genes responsible for SER, and demonstrated that the Hua6S allele of qSE1 and the B805D allele of qSE9 can effectively increase SER, which could make important contributions to the genetic improvement of MSLs aimed at improving hybrid seed production.…”
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  20. 43460

    Rethinking timing residuals: advancing PET detectors with explicit TOF corrections by Stephan Naunheim, Stephan Naunheim, Luis Lopes de Paiva, Luis Lopes de Paiva, Vanessa Nadig, Yannick Kuhl, Yannick Kuhl, Stefan Gundacker, Stefan Gundacker, Florian Mueller, Volkmar Schulz, Volkmar Schulz, Volkmar Schulz, Volkmar Schulz

    Published 2025-04-01
    “…PET is a functional imaging method that can visualize metabolic processes and relies on the coincidence detection of emitted annihilation quanta. …”
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