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43441
Long COVID in people with mental health disorders: a scoping review
Published 2025-07-01“…Little is known about individuals with pre-existing mental health conditions experiencing Long COVID. This scoping review aims to provide an overview of these individuals, focusing on: 1) the course of mental disorders, 2) care needs, 3) utilization of healthcare services, and 4) psychosocial aspects, as outlined by the International Classification of Functioning (ICF). …”
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43442
Short light/dark cycles favour photosynthetic efficiency and growth in grapevines
Published 2025-07-01“…Light and temperature in greenhouses or growth chambers are major regulatory factors in plant functioning, which can be easily modulated. Shortening the photo-/nycti-periods, compared to the standard cycle (12 h light/12 h dark), has been shown to enhance the photosynthetic activity and growth in annual crops, but its effect on perennial crops such as grapevines remains unexplored. …”
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43443
Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis
Published 2025-07-01“…Abstract Background Faecalibacterium prausnitzii plays a crucial role in ulcerative colitis (UC) remission, but its action mechanism is unknown. Here, we aimed to explore the potential mechanisms focusing on the interaction of F. prausnitzii with host immune response and its potential modulation on gut microbiome. …”
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43444
Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study
Published 2025-02-01“…Luminex multiplex ELISA were performed with lipoaspirates and cell supernatants alongside functional assays evaluating cell migration, proliferation, metabolic activity, and senescence.ResultsA total of 62 cytokines, chemokines, growth factors, neuropeptides, matrix-degrading enzymes, and complement components were identified in lipoaspirates. …”
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43445
Mobile genetic elements mediating antimicrobial resistance drive the evolutionary process of Clostridioides difficile ST37/RT017
Published 2025-07-01“…Furthermore, other functional genes, especially srtB, were notable in C. difficile ST37/RT017, which gradually acquired resistance genes from VL I to VL II and VL III. …”
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43446
Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury
Published 2025-01-01“…We previously reported that induced neural stem cells (iNSCs) can block the effects of CXCL12/CXCR4 signaling on NF-κB activation in activated microglia by CXCR4 overexpression. Here we aim to uncover the mechanism of CXCR4 upregulation in iNSCs. …”
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43447
Incidence of postoperative respiratory adverse events and its predictors among pediatric surgical patients at Hawassa University Comprehensive Specialized Hospital: a prospective f...
Published 2025-05-01“…BackgroundPostoperative respiratory adverse events are impairments in the normal functions of respiration resulting from the patient's condition, anesthesia, and surgery. …”
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43448
Artificial Intelligence in Medical Care – Patients' Perceptions on Caregiving Relationships and Ethics: A Qualitative Study
Published 2025-04-01“…Perceived main advantages of AI were its efficient and flawless functioning, its ability to process and provide large data volume, and increased patient safety. …”
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43449
Exploration of M2 macrophage-related biomarkers and a candidate drug for glioblastoma using high-dimensional weighted gene co-expression network analysis
Published 2025-06-01“…Subsequently, the clusterProfiler package was employed to functionally annotate the genes specifically highly expressed in the cells. …”
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43450
Does Robotic‐Assisted Total Knee Arthroplasty Improve Outcomes of Adult Osteoarthritis Patients—A Systematic Review and Trial Sequential Meta‐Analysis
Published 2025-06-01“…However, the comparative efficacy and safety of rTKA versus cTKA remain unclear due to inconsistent findings in existing studies. This study aims to systematically review and compare the efficacy and safety of rTKA and cTKA in patients with KOA. …”
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43451
Lyophilized human platelet lysate: manufacturing, quality control, and application
Published 2025-01-01“…The comparison of L-HPL with HPL did not reveal any relevant differences regarding quality control parameters of routine testing, growth factor concentrations and hMSC functionality, demonstrating the suitability of L-HPL as a cell culture supplement. …”
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43452
The First Experience of Using the Developed Modified Allogenic Bone Grafts in the Surgical Treatment of Patients With Severe Fractures of the Surgical Neck of the Humerus
Published 2021-04-01“…However, the incidence of unsatisfactory functional results after surgery remains high.AIM OF STUDY To develop allogeneic graft to strengthen the proximal humerus in the osteosynthesis of a comminuted fracture with a lack of bone tissue which has osteoconductive properties and capable of being a carrier of biologically active substances.MATERIAl AND METHODS The head, neck and portion of diaphysis of a fibula of a cadaver were used for a graft. …”
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43453
Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma
Published 2025-04-01“…Protein-protein interactions between PCNA and PARP1 were validated through co-immunoprecipitation and functional assays. The sensitivity of HCC cells to the PARP1 inhibitor Olaparib was evaluated under PCNA inhibition. …”
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43454
In-vitro and in-vivo assessment of biocompatibility and efficacy of ostrich eggshell membrane combined with platelet-rich plasma in Achilles tendon regeneration
Published 2025-01-01“…Despite advancements in tendon injury repair techniques, outcomes remain suboptimal due to inferior tissue quality and functionality. Tissue engineering offers a promising avenue for tendon regeneration, with biocompatible scaffolds playing a crucial role. …”
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43455
hucMSC-derived exosomes targeting macrophage polarization attenuate systemic inflammation in T1DM via INS/SOD1 delivery
Published 2025-07-01“…Proteomic profiling, pharmacological inhibition, and functional assays were employed to identify critical exosomal components. …”
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43456
A novel single-port robotic system in urology: A prospective multicenter single-arm clinical trial evaluating feasibility and efficacy of first 50 cases
Published 2025-04-01“…Objective: This study aimed to assess the feasibility and safety of the SHURUI single-port robotic surgical system for a range of major urological surgeries. …”
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43457
<i>Heortia vitessoides</i> Infests <i>Aquilaria sinensis</i>: A Systematic Review of Climate Drivers, Management Strategies, and Molecular Mechanisms
Published 2025-07-01“…Current research has preliminarily revealed its biological traits and gene functions. However, significant gaps persist in integrating climate adaptation mechanisms, control technologies, and host interaction networks across disciplines. …”
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43458
Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans
Published 2025-03-01“…The outcomes also provide valuable insights for future sustainability strategies aimed at enhancing greenness resilience in the central and southeast regions of the Sundarbans, ensuring the long-term preservation of the natural mangrove landscape.…”
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43459
Genetic Analysis and Fine Mapping of QTLs for Stigma Exsertion Rate in Rice
Published 2024-12-01“…A combination of sequencing, expression and haplotype analysis revealed that a single nucleotide variation (T to C) in the 5’UTR region of LOC_Os01g72020 (OsBOP1) was likely to be the functional variation for qSE1. Collectively, our work has laid a foundation for cloning the genes responsible for SER, and demonstrated that the Hua6S allele of qSE1 and the B805D allele of qSE9 can effectively increase SER, which could make important contributions to the genetic improvement of MSLs aimed at improving hybrid seed production.…”
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43460
Rethinking timing residuals: advancing PET detectors with explicit TOF corrections
Published 2025-04-01“…PET is a functional imaging method that can visualize metabolic processes and relies on the coincidence detection of emitted annihilation quanta. …”
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