Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon by Gustave Mabiama, Dieudonné Adiogo, Pierre Marie Preux, Jean-Claude Desport, Philippe Fayemendy, Pierre Jésus

“…However, little is known about Cameroon. This study aimed to assess the factors associated with DS and CI among older adults in Cameroon. …”
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Comorbidity Burden in Chronic Thromboembolic Pulmonary Hypertension: Implications and Outcome by Burcak Kilickiran Avci, Ibrahim Basarici, Mehmet Akbulut, Halil Atas, Yalin Tolga Yaylali, Umit Yasar Sinan, Ersan Atahan, Murat Meric, Baris Kaya, Kardelen Ohtaroglu Tokdil, Ozden Calay, Hasan Tokdil, Bulent Mutlu, Mehmet Serdar Kucukoglu, Zeki Ongen

“…<i>Conclusions</i>: A high comorbidity burden is common in CTEPH and influences functional status, hemodynamics, and operability decisions. …”
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A GWAS of angiotensin-converting enzyme inhibitor-induced angioedema in a South African population by Jacquiline W. Mugo, PhD, Cascia Day, Cert Allergy (Phys), Ananyo Choudhury, PhD, Maria Deetlefs, Dip Allergy (SA), Robert Freercks, MPhil, Sian Geraty, MMed, Angelica Panieri, MBChB, Christian Cotchobos, MBChB, Melissa Ribeiro, MBChB, Adelein Engelbrecht, MMed, Lisa K. Micklesfield, PhD, Michèle Ramsay, PhD, Sarah Pedretti, PhD, Jonny Peter, PhD

“…Further increased sampling across the continent and matched functional work are needed to confirm the importance of genetic variation in understanding the biology of AE-ACEI.…”
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Effects of stand structure and soil depth on soil properties in Cryptomeria japonica plantations by Laicong Luo, Kang Lin, Lingjian Tao, Chao Luo, Jianming Wang, Tianze Duan, Yubing Liu, Xiaobin Fu, Siqin Guo, Yuanqiu Liu

“…These findings provide a scientific basis for sustainable forest management, suggesting that optimizing stand structure can enhance soil health and overall ecosystem functionality.…”
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Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson’s Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study by Lydia López-Manzanares, Juan García Caldentey, Marina Mata Álvarez-Santullano, Dolores Vilas Rolán, Jaime Herreros-Rodríguez, Berta Solano Vila, María Cerdán Sánchez, Tania Delgado Ballestero, Rocío García-Ramos, Ana Rodríguez-Sanz, Jesús Olivares Romero, José Blanco Ameijeiras, Isabel Pijuan Jiménez, Iciar Tegel Ayuela

“…Objective: We aimed to analyze the real-world use of COMT inhibitors associated with levodopa in patients with Parkinson’s disease (PD) who present early fluctuations and to explore whether early COMT inhibition optimizes treatment outcomes. …”
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2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablation and left a... by Andrea Maria Paparella, Luigi Pannone, Gianni Pedrizzetti, Giacomo Talevi, Domenico Giovanni Della Rocca, Antonio Sorgente, Rani Kronenberger, Gaetano Paparella, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Juan Sieira, Mark La Meir, Andrea Sarkozy, Pedro Brugada, Gian Battista Chierchia, Ali Gharaviri, Carlo De Asmundis

“…Background and aimsHybrid atrial fibrillation (AF) ablation is a therapeutic option in non-paroxysmal AF. …”
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Assessment of EMF Exposure Induced by Wireless Cellular Phones in Various Usage Scenarios in France by Jiang Liu, Yarui Zhang, Wassim Ben Chikha, Shanshan Wang, Theodoros Samaras, Ourouk Jawad, Lamine Ourak, Emmanuelle Conil, Joe Wiart

“…To assess the impact of 5G, we used NEMO system from Keysight to conduct measurements with the 5G functionality enabled and disabled, respectively. The data analysis revealed that mobile phones emit higher power during data-intensive services. …”
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Development of a Recombinant Fusion Vaccine Candidate Against Lethal <i>Clostridium botulinum</i> Neurotoxin Types A and B by Eun-Sun Choi, Seong-Wook Pyo, So-Hyeon Kim, Jun-Ho Jeon, Gi-Eun Rhie, Mi-Ran Yun, Hwajung Yi, Yoon-Seok Chung

“…BoNTs comprise three functional domains: a light-chain enzymatic domain (LC), a heavy-chain translocation domain (HC_N), and a heavy-chain receptor-binding domain (HC_C). …”
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Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats by Wenli Zou, Yueming Liu, Wei Zhang, Bo Lin, Wei Shen, Yiwen Li, Qiang He, Juan Jin

“…In addition, KEGG metabolic prediction revealed different metabolic functions in each group. TEM examination of colon revealed that dramatic morphological changes were observed in the ceftriaxone (Cef) group, wherein microvilli were misaligned and shortened significantly and morphologically intact bacteria were seen on the epithelial cell surface. …”
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Association between care complexity individual factors and older inpatients with COVID-19: a cross-sectional study by Jordi Adamuz, Jordi Adamuz, Jordi Adamuz, Julia González-Vaca, Julia González-Vaca, Maribel González-Samartino, Maribel González-Samartino, Maribel González-Samartino, María-Magdalena López-Jiménez, María-Magdalena López-Jiménez, María-Magdalena López-Jiménez, Andrea Urbina, Andrea Urbina, Andrea Urbina, Oliver Polushkina-Merchanskaya, Sergio Alonso-Fernández, Sergio Alonso-Fernández, Silvia Esteban-Sepúlveda, Silvia Esteban-Sepúlveda, Sergio Barrientos-Trigo, Maria-Eulàlia Juvé-Udina, Maria-Eulàlia Juvé-Udina

“…The analysis shows that middle-old (75–84 years) patients were associated with chronic disease, position impairment, urinary or fecal incontinence, anatomical and functional disorders, vascular fragility, involuntary movements, fear or anxiety and mental status impairments. …”
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Vitamin D receptor genetic variations in association to the susceptibility to prostate cancer: a case-control study in a Moroccan population by Kawtar Nabil, Abdelilah Laraqui, Ikram Tiabi, Kaoutar Anouar Tadlaoui, Mohammed Mrabti, Ahmed Ameur, Khalid Ennibi, Mustapha Benhessou, Moulay Mustapha Ennaji

“…Aim: It has been shown that the vitamin D receptor (VDR) gene and its biological functions can be affected by genetic alterations in the VDR gene. …”
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Why do patients with isolated PCL rupture experience no subjective knee joint instability during walking? An in vivo biomechanical study by Mingfeng Lu, Mingfeng Lu, Wei Chen, Jinpeng Lin, Jinpeng Lin, Wenhan Huang, Junqing Gao, Junqing Gao, Lilian Zhao, Shilin Li, Lilei He, Yu Zhang

“…Clinical evaluations of PCLD should incorporate dynamic functional assessments, thereby providing a more comprehensive basis for treatment decisions.…”
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Validity and Reliability of a Mobile Device Application for Assessing Motor Performance in the 30-Second Sit-to-Stand Test by Eduardo Candido Veloso Ferreira, Amelia Pasqual Marques, Szymon Kulis, Jan Gajewski, Anderson Antunes da Costa Moraes, Manuela Brito Duarte, Gizele Cristina da Silva Almeida, Enzo Gabriel da Rocha Santos, Gustavo Henrique Lima Pinto, Andre Dos Santos Cabral, Givago da Silva Souza, Anselmo De Athayde Costa E Silva, Bianca Callegari

“…This study aimed to test the validity and reliability of a mobile device application for capturing center of mass (CoM) acceleration signals in analyzing and describing events during the 30-second chair stand test. …”
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Study protocol: a randomized controlled clinical trial on the use of electroacupuncture for postoperative abdominal distension following laparoscopic cholecystectomy by Qi Kong, Qi Kong, Qi Kong, Wei Wang, Xin-Yi Chen, Li-Ming Chen, Long-Kai Sun, Long-Kai Sun, Shao-Hua Qu, Wen-Tao Wu, Jia-Hua Yang, Yu Shu, Sen Li, Pei-Hao Yin, Pei-Hao Yin, Pei-Hao Yin, Wei Li, Wei Li

“…Previous studies have confirmed the effectiveness of acupuncture intervention for gastrointestinal functionality.MethodThis study is a randomized, single-blind, controlled pilot clinical trial. …”
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Enhancing nurses’ communication about psychosocial needs and changes in intimacy and sexuality in patients with advanced cancer: a mixed-method study by Susanne A.M. Arends, Corien M. Eeltink, Floortje K. Ploos van Amstel, Astrid W. Oosten, Donna C. Ruijter, Nelleke van der Loo, Barbara Harterink-Poker, Anneke L. Francke, Irene P. Jongerden

“…Conclusion: After the programme, more nurses felt competent in discussing psychosocial needs in patients with advanced cancer, especially with regard to changes in intimacy and sexual functioning. The training had little effect on nurses’ notes about psychosocial needs in patient records; the focus remained on physical aspects. …”
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Endothelial Cell Senescence in Marfan Syndrome: Pathogenesis and Therapeutic Potential of TGF‐β Pathway Inhibition by Yuhao Chen, Yuankang Zhu, Xiaoli Ren, Lu Ding, Yubin Xu, Miqi Zhou, Runze Dong, Peifeng Jin, Xiufang Chen, Xiaofang Fan, Ming Li, Yongsheng Gong, Yongyu Wang

“…These MFS–hiPSC‐derived ECs were characterized using immunofluorescence, reverse transcription‐quantitative polymerase chain reaction, and Western blotting. Functional assays including cell proliferation, scratch wound, tube formation, NO content detection, and senescence‐associated β‐galactosidase staining were conducted. …”
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Electroacupuncture treatment for sarcopenia: study protocol for a randomized controlled trial by Hao Li, Li Zhou, Xin Zhang, Qian Wen, Li Tian, Han Yang, Xirong Chen, Jinghan Yuan, Ning Li, Bingmei Zhu, Lin Zhang, Lingyun Lu

“…Sarcopenia has an insidious onset which can cause functional impairment in the body and increase the risk of falls and disability in the elderly. …”
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95 Assessing genetic diversity of the Pfs25 vaccine candidate: Implications for malaria transmission-blocking vaccine in Africa by Alessandra Orfano, Awa Cisse, Zizhang Sheng, Yicheng Guo, Leeah Han, Laty G. Thiam, Khadidiatou Mangou, Adam J. Moore, Aboubacar Ba, Rebecca Li, Mariama N. Pouye, Fatoumata Diallo, Seynabou D. Sene, Elhadji Malick Ngom, Bacary D. Sadio, Alassane Mbengue, Christopher Membi, Thomas Bazié, Fabrice Anyirékun Somé, Natalie Olson, Saurabh Patel, Lawrence Shapiro, Sunil Parikh, Brian Foy, Michael Cappello, Zul Premji, Roch K. Dabiré, Jean-Bosco Ouedraogo, Amy K. Bei

“…Further research exploring the functional implications of these variations will be important to elucidate their role in malaria transmission.…”
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Impacts of parental genomic divergence in non-syntenic regions on cotton heterosis by Chujun Huang, Yu Cheng, Yan Hu, Xuemei Zhang, Jinwen Chen, Ting Zhao, Zhanfeng Si, Yiwen Cao, Yiqian Li, Lei Fang, Xueying Guan, Tianzhen Zhang

“…We characterized numerous parental-specific introgressions from G. barbadense. Specifically, a functional introgression segment within non-syntenic blocks introduced an elite haplotype, which significantly increased lint yield and enhanced heterosis. …”
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Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening by Diego Benítez, Jaime Franco, Florencia Sardi, Alejandro Leyva, Rosario Durán, Gahee Choi, Gyongseon Yang, Taehee Kim, Namyoul Kim, Jinyeong Heo, Kideok Kim, Honggun Lee, Inhee Choi, Constantin Radu, David Shum, Joo Hwan No, Marcelo A. Comini

“…A drug discovery campaign aimed to identify and characterise new inhibitors of TryS with promising biological activity was conducted. …”
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