Monitoring the Landscape Changes Applying Gradient Analysis Case Study (County Behbehan) by Mir Mehrdad Mirsanjari, Fatemeh Mohammadyari

“…In order to evaluate the socioeconomic and ecological functions of a city, it is essential to quantify the pattern of the land. …”
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El patrimonio cultural: una propuesta de gestión participativa / The cultural heritage: participative management proposal by Mª del Carmen Garrido Arroyo, Ana Mª Hernández Carretero

“…The management of cultural property, both tangible and intangible, provides different models of intervention and, depending on the model adopted, schedules pose different objectives are different stakeholders and the functions and / or tasks to be carried out also vary. …”
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[Artículo traducido] Análisis Rasch del índice de calidad de vida en dermatología by G. Sanclemente, C. Mora-Gaviria, D.C. Aguirre-Acevedo

“…Therefore, we aimed to assess the structural validity, internal consistency and item response analysis of the DLQI through the item response theory (IRT) or the Rasch model. …”
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Rasch Analysis of the Dermatology Life Quality Index by G. Sanclemente, C. Mora-Gaviria, D.C. Aguirre-Acevedo

“…Background and aims: Previous results of the Dermatology-Life-Quality-Index (DLQI) validation in Colombia based on the classical test theory (CTT) perspective have showed the need to delve into its measurement properties. …”
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Pathway for Renewable Energy Application in Urban Green Space under the Low Carbon Perspective by Kailun WANG, Tonggang NIU, Lian LIU, Zhongjie WANG

“…The proposed framework aims to optimize the energy structure of green spaces and enhance their carbon reduction effectiveness. …”
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Surgical Treatment of Cerebral Aneurysms in the Acute Period of Subarachnoid Hemorrhage: Long-Term Result by I. M. Shetova, V. D. Shtadler, P. D. Matveev, V. A. Lukyanchikov, V. V. Krylov

“…The patient’s age at the time of rupture of the aneurysm independently influenced cognitive functions and the ability to self-care in the long-term period. …”
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Environmentally Friendly Synthesis of New Mono- and Bis-Pyrazole Derivatives; In Vitro Antimicrobial, Antifungal, and Antioxidant Activity; and In Silico Studies: DFT, ADMETox, and... by Oussama Merzouki, Nadia Arrousse, Elhachmia Ech-chihbi, Ashwag S. Alanazi, El Houssine Mabrouk, Mohamed Hefnawy, Abdelfattah El Moussaoui, Hanane Touijer, Azeddin El Barnossi, Mustapha Taleb

“…Pyrazole derivatives, known for their diverse pharmacological properties, hold promise in addressing these issues. This study aimed to synthesize new mono- and bis-pyrazole derivatives using an eco-friendly, catalyst-free approach and evaluate their antioxidant, antibacterial, and antifungal activities, supported by in silico ADMET profiling, molecular docking, and Density Functional Theory (DFT) analysis. …”
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Prevalence, distribution and future projections of Parkinson disease in Brazil: insights from the ELSI-Brazil cohort studyResearch in context by Thomas Hugentobler Schlickmann, Marcelo Somma Tessari, Wyllians Vendramini Borelli, Gabriel Alves Marconi, Gabriela Magalhães Pereira, Eduardo Zimmer, Alastair Noyce, Ignacio Fernandez Mata, Carlos Roberto de Mello Rieder, Daniel Teixeira-dos-Santos, Artur Francisco Schumacher Schuh

“…PD individuals had higher rates of stroke, depression, functional dependency, and were more likely to need walking support or be bedridden. …”
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Inhibition of SIRT3 by a specific inhibitor induces cellular senescence and growth arrest of ovarian granulosa cell tumor via p53 and NF-κB axis by Jingxin Ma, Sailing Lin, Chuimian Zeng, Wenhao Wu, Qi Zhang, Guli Zhu, Qi Zhang, Qiongfang Fang, Lijun Fan, Shunichi Takeda, Xiaoyu Li, Xiaoyu Li, Xiushen Li, Yu Zhou, Xueqing Wu

“…SIRT3, an NAD + -dependent deacetylase, is upregulated in GCTs and implicated in tumorigenesis, yet its functional role and underlying mechanisms remain poorly understood. …”
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ANALYSIS OF DIFFERENTIAL ExPRESSION OF MATRIx METALLOPROTEASES IN STABLE AND UNSTABLE ATHEROSCLEROTIC LESIONS BY A METHOD OF FULL GENOME SEQUENCING OF RNA: PILOT STUDY by D. Е. Ivanoschuk, Yu. I. Ragino, E. V. Shakhtshneider, S. V. Mikhailova, V. S. Fishman, Ya. V. Polonskaya, E. V. Kashtanova, A. M. Chernyavsky, I. S. Murashov, М. I. Voevoda

“…Aim. To analyze differential expression of metalloproteases genes, involved into the processes of stabilization/destabilization of atherosclerotic plaque, with the method of full genome sequencing of RNA, and to evaluate the level of metalloproteases in homogenates of plaques of various types by immune enzyme assay method (IEA).Material  and  methods.  …”
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Indoleamine 2,3-dioxygenase 1-mediated immune suppressive status is positively associated with brain metastasis in patients with non-small cell lung cancer by Weiwei Chen, Li Yang, Victor Ho-fun Lee, Liangliang Xu, Lingyu Ma, Zhenghao Ye, Wanli Xu, Caining Zhao, Danyang Zheng, Karrie Mei-Yee Kiang, Stella Sun, Yuan Qu, Jiandong Zha, Dazhi Pang, Yan Zhang, Zhibing Liang, Wenchu Lin, Jinliang Zhang, Jitian Zhang, Min Luo, Zhiyuan Xu, Ding Li, Xiaoling Liang, Gilberto Ka-Kit Leung, Aya El Helali, Chiming Che, Feng-Ming (Spring) Kong

“…Background: Indoleamine 2,3-dioxygenase (IDO1) activity, measured by kynurenine/tryptophan (K:T) ratio, is known for its association with distant metastasis and overall survival (OS) in patients with non-small cell lung cancer (NSCLC). Here, we aimed to examine whether IDO1 activity is correlated with OS in NSCLC patients with brain metastasis (Bramet) and has negative effect on modulating the anti-tumor functions of immune cells. …”
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Simultaneous binding of quercetin and catechin to FOXO3 enhances IKKα transcription inhibition and suppression of oxidative stress-induced acute alcoholic liver injury in rats by Hui Guan, Wenyuan Zhang, Hui Liu, Yang Jiang, Feng Li, Dan Wang, Yang Liu, Fatao He, Maoyu Wu, Geoffrey Ivan Neil Waterhouse, Dongxiao Sun-Waterhouse, Dapeng Li

“…This research opens new vistas for examining the joint effect of therapeutics towards functional proteins and confirms the chemopreventive effects of multiple flavonoids via co-regulation.…”
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Sex differences and rehabilitation needs after hospital discharge for COVID-19: an Italian cross-sectional study by Luca Braglia, Monica Denti, Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Monia Allisen Accogli, Ginevra Bedogni, Daniele Ghizzoni, Anna Bertolini, Otmen Esseroukh, Cecilia Gualdi, Margherita Schiavi

“…Objectives COVID-19 can result in persistent symptoms leaving potential rehabilitation needs unmet. This study aims to describe persistent symptoms and health status of individuals hospitalised for COVID-19 according to the International Classification of Functioning, Disability and Health domains of impairments, limitations in activity, and participation restrictions.Design Cross-sectional study consisting in a telephone interview 3 months after hospital discharge.Setting This study was conducted during the first peak of the COVID-19 pandemic by the Local Health Authority of Reggio Emilia (Italy).Participants Adult individuals discharged from hospital between April and June 2020 after COVID-19. …”
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Use of dehydrated carrot (Daucus carota) pomace and almond (Prunus dulcis) powder for partial replacement of wheat flour in cake: effect on product quality and acceptability by Tusneem Kausar, Salah Laaraj, Ashiq Hussain, Younes Noutfia, Mohamed Bouhrim, Ramzi A. Mothana, Omar M. Noman, Aymen Mubashar, Nida Firdous, Shafiqa Ali, Shazia Yaqub, Kaoutar Elfazazi

“…IntroductionCarrot (Daucus carota) is a nutrient-dense root vegetable, and carrot pomace is a by-product of the juice extraction procedure, which is recognized a source of phytochemicals and functional components. Almonds (Prunus dulcis) are packed with a decent amount of nutrients and bioactives.MethodsThis study investigates the utilization of carrot pomace powder (CPP) and almond powder (AP) as partial substitutes for straight grade white flour (SGWF) in cakes to enhance their nutritional value and sensory appeal, while reducing waste from carrot processing. …”
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Effects of Lactic Acid Bacteria Fermentation on the Basic Composition, Probiotic Activity, and in vitro Digestive Characteristics of Longan Pulp by Weiwei SONG, Fei HUANG, Ruifen ZHANG, Xuchao JIA, Lihong DONG, Qin MA, Shan LIANG, Yongxuan MA

“…【Objective】The aim of this study was to investigate the effects of lactic acid bacteria complex fermentation on the basic composition, probiotic activity and in vitro digestion characteristics of longan pulp, so as to provide a theoretical basis for the development of functional longan products.…”
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Multicentre pragmatic embedded stepped wedge cluster randomised trial comparing glucose 5% with sodium chloride 0.9% as the default drug diluent in the ICU: the sweet-water trial p... by Alexander Zarbock, Kai-Uwe Eckardt, Claudia Spies, Felix Balzer, Martin Witzenrath, Philipp Enghard, Björn Tampe, Oliver Hunsicker, Steffen Weber-Carstens, Bjoern Weiss, Jens Nee, Christian Strauss, Heiko Schenk, Jan-Hendrik Bernhard Hardenberg, Ricarda Merle Hinz, Mareen Pigorsch, Alexander Uhrig, Holger Müller-Redetzky, Tim Schroeder, Ulrike Trost, Daniel Zickler, Rainer Borgstedt, Mariam Abu-Tair, Uta Hildebrand, Dario von Wedel

“…Hypernatraemia adversely affects various physiological functions and is associated with delirium, prolonged length of stay and increased ICU and post-discharge mortality. …”
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Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course by Elisabetta Zucchi, Elisabetta Zucchi, Federico Banchelli, Cecilia Simonini, Sara De Biasi, Ilaria Martinelli, Giulia Gianferrari, Giulia Gianferrari, Domenico Lo Tartaro, Andrea Cossarizza, Andrea Cossarizza, Roberto D’Amico, Roberto D’Amico, Jessica Mandrioli, Jessica Mandrioli

“…IntroductionT regulatory cells (Tregs) inversely correlate with disease progression in Amyotrophic Lateral Sclerosis (ALS) and fast-progressing ALS patients have been reported to exhibit dysfunctional, as well as reduced, levels of Tregs. This study aimed to evaluate the longitudinal changes in Tregs among ALS patients, considering potential clinical and biological modifiers of their percentages and concentrations. …”
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Physical activity coaching for adults with mobility limitations: protocol for the ComeBACK pragmatic hybrid effectiveness-implementation type 1 randomised controlled trial by Kirsten Howard, Anne Tiedemann, Catherine Sherrington, Tammy Hoffmann, Kim L Bennell, Colin Greaves, Rana S Hinman, Nicholas F Taylor, Andrew Milat, Marina Pinheiro, Leanne Hassett, Maria Crotty, Lisa Harvey, Daniel Treacy, Matthew Jennings, Maayken van den Berg, Siobhan Wong, Catherine Kirkham, Elizabeth Ramsay, Sandra O'Rourke

“…Secondary outcomes include other physical activity measures, measures of health and functioning, individualised mobility goal attainment, mental well-being, quality of life, rate of falls, health utilisation and intervention evaluation. …”
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Intrinsic capacity in patients with dementia with Lewy bodies compared with those with Alzheimer’s disease: A cross-sectional study by Marie Collin, Justine Bonnet-Chateau, Victor Gilles, Sophie Dautricourt, Thomas Gilbert, Zaza Makaroff, Marie-Hélène Coste, Virginie Dauphinot, Antoine Garnier-Crussard

“…The aim of this cross-sectional study was to describe the frequency of IC decline in DLB and to compare it with AD. …”
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Differentiating between adrenocortical carcinoma and pheochromocytoma by a CT-based radiomics model: a multicenter retrospective study by Yinyao Chao, Hongzhang Zhu, Wenyi Yang, Haohua Yao, Nan Ma, Xianda Chen, Jing Zhao, Huali Ma, Zhenhua Liu, Hui Han, Zhuowei Liu, Kai Yao, Yiyao Li, Peng Wu, Jingtong Zhang, Bin Li, Shengjie Guo

“…This study aims to differentiate between large (≥ 4 cm) ACC and PHEO with radiomics features based on contrast-enhanced CT. …”
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