DIFFERENTIATED EFFECTS OF GLUCOSAMINYLMURAMILDIPEPTIDE ON THE NONTRANSFORMED AND EXPERIMENTALLY TRANSFORMED PHENOTYPE OF CD62L+CD63+CD66d+ NEUTROPHILIC GRANULOCYTES IN CONVENTIONAL... by I. V. Nesterova, V. V. Malinovskaya, S. V. Khaydukov, D. L. Nguyen Thi, G. A. Chudilova, L. V. Lomtatidze

“…Modern studies have shown a high plasticity and phenotypic diversity of neutrophilic granulocytes (NG) provided by different receptors, which are diagnostic markers for the functional capacity of the cell in the course of their activities. …”
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THE PECULIARITIES OF CALCIUM-PHOSPHORUS METABOLISM IN YOUNG CHILDREN by E.G. Yaroshenko, I.I. Sokolova

“…Connective-tissue dysplasia is a developmental disorder of the connective tissue in embryonic and postnatal periods as a result of genetically modified fibrillogenesis in the extracellular matrix, leading to homeostasis disorders at the tissue, organ, and organism levels in the form of a variety of morphological and functional defects of visceral and locomotive organs with a progressive course. …”
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Non-linear associations and threshold effects of BRI, CI, and WHtR with grip strength in U. S. adults aged ≥20 years: a cross-sectional study by Sijia Yang, Kun Liao, Lu Zhou, Shengbo Zhang, Jianchao Wu

“…BackgroundMuscle strength is strongly associated with various physiological functions and health risks, with grip strength serving as a key indicator for its assessment. …”
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Patients’ daily reporting of symptoms via mobile application reveals a significant difference between patients’ perceptions and doctors’ interpretations by Cvetka Grašič Kuhar, Cvetka Grašič Kuhar, Nina Privšek, Nina Privšek, Marjetka Sraka, Marjetka Sraka, Ema Grašič, Ema Grašič, Timotej Kovač, Matjaž Kukar

“…PurposeElectronic patient-reported outcomes (ePROs) are gaining importance. The aim of this study was to investigate the difference in the reporting of symptoms between patients via mobile application (m-app) and doctor assessments. …”
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THE CONCEPT OF A COMPREHENSIVE PROGNOSTIC MODEL OF THE EFFECTIVENESS OF IMPLEMENTATION OF MINIMALLY INVASIVE INTERVENTIONS IN THE TREATMENT OF CARIOUS PATHOLOGY by S.B. Kostenko, O.Ya. Bilynskyi, G.N. Nakashydze, M.O. Stetsyk, M.Yu. Goncharuk-Khomyn, I.V. Penzelyk

“… The research presents a prognostic model of the effectiveness of minimally invasive interventions in the dental patients’ treatment of carious pathology, which was developed to reduce the impact of iatrogenic interventions, increase the results of biological, biomechanical and financial feasibility of treatment. The aim of research is to develop a mathematical representation of a comprehensive prognostic model of the minimally invasive treatment effectiveness of carious pathology. …”
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Validation of the de Morton Mobility Index for measuring mobility related activities in Hungarian institutionalized older adults by Zsigmond Gyombolai, Alexandra Zimonyi-Bakó, Anna Zsófia Kubik, Brigitta Arndt, Izabella Jónásné Sztruhár, Richárdné Mayer, András Simon, Gyöngyvér Molnár, Éva Kovács

“…Maintaining institutionalized older people’s functional capacity and delaying its decline requires effective interventions. …”
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Effects of Walnut Protein Peptides on Promotion of White Adipose Tissue Browning and Prevention of Obesity by Yankun FU, Yuzheng CAI, Zhiqiang FENG, Siru CHEN, Tianlin WANG, Lianjun SONG, Tiange LI

“…Objective: The aim of this study was to investigate the effect of walnut protein peptides (WPP) on the promotion of white adipose tissue (WAT) browning to prevent obesity. …”
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Relationship between CTF1 gene expression and prognosis and tumor immune microenvironment in glioma by Hongqing Cai, Shen Tian, Angsi Liu, Guanchao Xie, Hongsheng Zhang, Xiaogang Wu, Jinghai Wan, Sai Li

“…Abstract Objective This study aimed to evaluate CTF1 expression in glioma, its relationship to patient prognosis and the tumor immune microenvironment, and effects on glioma phenotypes to identify a new therapeutic target for treating glioma precisely. …”
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Exploring the active chemical compounds and pharmacological effects of Artemisia Argyi leaves through commonality, authenticity and aging by Boyu Chen, Jiaxin Liu, Xu Dai, Lufan Xu, Wenying Cui, Rouan Chen, Tian Lan, Yiider Tseng

“…Purpose: Hence, this study aims to extract key bioactive compounds contributing to its medicinal properties by performing data mining from literature. …”
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Gender and age-related variations in rumen fermentation and microbiota of Qinchuan cattle by Yueting Pan, Huaxuan Li, Juze Wang, Xiaolei Sun, Entang Liang, Juntao Guo, Jianfang Wang, Ke Zhang, Bingzhi Li, Mengqi Zan, Wucai Yang, Linsen Zan

“…Objective Our study aimed to investigate the gender and age-related variations in rumen fermentation, serum metabolites, and microbiota in Qinchuan cattle. …”
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The Role of Potassium and KUP/KT/HAK Transporters in Regulating Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruit Development by José A. Mercado-Hornos, Claudia Rodríguez-Hiraldo, Consuelo Guerrero, Sara Posé, Antonio J. Matas, Lourdes Rubio, José A. Mercado

“…This pattern suggests their functional relevance in early fruit development and turgor maintenance. …”
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma by Yonglin Luo, Wenyang Wei, Yaxuan Huang, Jun Li, Weiling Qin, Quanxiang Hao, Jiemei Ye, Zhe Zhang, Yushan Liang, Xue Xiao, Yonglin Cai

“…The low-risk score group exhibited features indicative of early clinical stage, immune activation, high immune checkpoint gene's expression, and low Epstein-Barr virus gene's expression. Functional analysis revealed enrichment of immune-related pathways in the low-risk group. …”
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Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma by Xin Li, Juxuan Zhang, Meng Zhang, Wenbin Jiang, Dexin Jia, Ruxiong Wang, Hao Li, Zhihui Wang, Yixin Liu, Lefan Tang, Jiaxing Deng, Wenyuan Zhao, Yan Yu, Shilong Liu, Lishuang Qi

“…Immunohistochemical results confirmed that patients exhibiting high PSMD12 protein expression had a significantly higher incidence of BM within 5 years and shorter progression-free survival. Functional experiments revealed that PSMD12 overexpression in A549 cells disrupted BBB integrity and enhanced tumor cell invasiveness, whereas PSMD12 knockdown attenuated these effects. …”
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Family dynamics and diagnostic delay among pulmonary tuberculosis patients in Ile-Ife, South-Western Nigeria by Ayanleye Ahmed Abdulakeem, Oloyede Oyegbade Olanrewaju, Olurotimi Ogundokun Akinjide, Fehintola Awopeju Olayemi, Sebutu Bello Ibrahim, Anu Olowookere Samuel, Oluwafemi Olajubu Temitope, Olalekan Ismail Waheed, Kolawole Adewumi Muideen, Omowonuola Sonibare Olubukola, Oladeji Gbadamosi Moroof, Oyemomi Ibrahim Azeez

“…Results: The family dynamics of the respondents showed that 68.1% of them had strong family support, with about two-thirds (69.1%) having functional families. The median diagnostic delay before diagnosis was 45 days (range 9–217 days). …”
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Impact of dietary mulberry (Morus alba) fruit extract on the growth performance, skin color, and immune response of fancy carp (Cyprinus carpio) by Wassana Prisingkorn, Prasoborn Rinthong, Narong Kamolrat, Pattama Wiriyapattanasub, Sutee Wongmaneeprateep, Jariyavadee Suriyaphan, Apichet Pholoeng, Eakapol Wangkahart

“…Supplementing aquafeed with functional ingredients can improve fish immunity, growth performance, and survival rates. …”
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Genetic variations in the IDUA gene in Tunisian MPS I families: Identification of a novel microdeletion disrupting substrate binding and structural insights by Mariem Rebai, Yessine Amri, Chaima Sahli, Hajer Foddha, Taieb Messaoud, Hela Boudabous, Hassen Ben Abdennebi, Salima Ferchichi, Latifa Chkioua

“…MPS I presents with a broad spectrum of clinical phenotypes, ranging from severe to mild. This study aimed to identify genetic mutations in the IDUA gene among Tunisian families and assess their structural and functional implications. …”
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Multi-model quantitative MRI of uterine cancers in precision medicine’s era—a narrative review by Marco Gennarini, Rossella Canese, Silvia Capuani, Valentina Miceli, Federica Tomao, Innocenza Palaia, Valentina Zecca, Alessandra Maiuro, Ilaria Balba, Carlo Catalano, Stefania Maria Rita Rizzo, Lucia Manganaro

“…By focusing on functional imaging techniques, we explore how these biomarkers enhance personalized cancer management beyond traditional morphological assessments. …”
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Comparison of the Sensitivity of 68Ga-DOTATATE PET/CT with Other Imaging Modalities in Detecting Head and Neck Paraganglioma: Experience from Western India by Manjunath Havalappa Dodamani, Sanjeet Kumar Jaiswal, Vijaya Sarathi, Hetal Marfatia, Anil D'Cruz, Gaurav Malhotra, Priya Hira, Virendra A. Patil, Anurag R. Lila, Nalini S. Shah, Tushar R. Bandgar

“…Background This study aimed to compare the sensitivity of 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) with other imaging modalities in the detection of head and neck paraganglioma (HNPGL). …”
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UBE2D1 as a key biomarker in systemic juvenile idiopathic arthritis: a new perspective on diagnosis and disease activity assessment by Qiang Luo, Han Hao, Luo Xiwen, Xiang Qiu, Dawei Liu, Yun Liu, Fengning Li, Kening Lu, Xiya Luo, Chenxi Ma, Xiaodong Zhao, Yunfei An, Xuemei Tang

“…Abstract Background Early diagnosis is crucial for reducing disability and improving long-term prognosis in patients with systemic Juvenile Idiopathic Arthritis (sJIA), but it remains a significant challenge. This study aims to identify non-invasive biomarkers with superior diagnostic efficacy for sJIA. …”
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Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis by Lingzhi Huang, Xinyi Chen, Yawen Shao, Shujun Deng, Chen Wang, Jianqiao Chen, Yongsheng Xie, Siming Yuan, Liqin Tang

“…The deletion of ISG15 alleviated renal functional damage, fibrosis and inflammation, which correlated with reduced ISGylation levels. …”
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