Exploring the mechanism of Bu Zhong Yi Qi Tang in the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) based on network pharmacology and molecular docking by Pengfei Zhou, Yang Xuan, Zaisheng Zhu, Han Wu, Yang Hu, Liangyou Chen, Qianya Zhou

“…Key targets were further subjected to Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. …”
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In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug D... by Obinna C. Ubah, Andrew J. Porter, Caroline J. Barelle

“…Trough serum Humira® and Quad-X™ concentrations in 3 mg/kg treatment samples were comparable; however, the functionality of the detected Humira® serum was significantly compromised due to neutralising ADA. …”
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Professional-applied physical training of future specialists in the oil and gas industry with the predominant use of the game method by Roman Boichuk, Oleh Vintonyak, Volodymyr Kryzhanivskyi, Roman Mikhailenko, Andriy Shankovskyi, Ihor Belyavskyi, Andriy Hrabchuk

“…Background and Study Aim. Physical training plays a crucial role in preparing future specialists for the demands of the oil and gas industry, where physical endurance and coordination are essential for professional activities. …”
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Epidemiological Situation on Tularemia in the far Eastern Federal District (2000-2017) by T. N. Demidova, V. P Popov, T. V. Mikhailova, A. S. Cemichin, Y. S. Podobedova

“…Tularemia is a particularly dangerous infection, is included in the second group of pathogenicity.Aims. The purpose of this work is to identify the main patterns of functioning and epidemic manifestations of natural foci of tularemia in the far Eastern Federal district (far Eastern Federal district) on the basis of long-term monitoring and using various research methods.Results, The analysis of the epizootic state and epidemic manifestation of natural foci of tularemia in the territory of the far Eastern Federal district for 2000-2017 shows that the main regularities of the epidemic process remain in the natural foci of this infection. …”
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DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…The article examines the mechanisms of the heterocyclization reaction using density functional theory (DFT) methods. A quantum-chemical analysis of the starting compounds, transition states, and products was conducted, with energy barriers and key reaction stages identified. …”
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AIRWAY ASSESSMENT IN OUTPATIENT DENTAL PRACTICE by I. А. Khrypachenko, T. V. Diomina, O. А. Udod

“… The aim of this paper was to represent up-to-date data about airway assessment in outpatient dental practice. …”
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Latent profile analysis and influencing factors of post-traumatic stress disorder symptoms in young and middle-aged spinal cord injury patients by Songbo Jia, Zhenzhen Wang, Qiaoju Yang, Jiayi Guan, Yange Yang, lijun Min

“…Abstract Background Post-traumatic stress disorder (PTSD) has a profound impact on the physiological, psychological, social functioning, and occupational development of young and middle-aged spinal cord injury (SCI) patients, with a multitude of factors influencing its manifestation. …”
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Are Rain Gardens Resistant to Salinization Stresses? The Consequences of De-Icing Chemicals’ Implementation for Soil Health, Plant Condition, and Groundwater Quality by Olga Romzaykina, Viacheslav Vasenev, Ekaterina Kozlova, Igor Shchukin, Artem Losev, Andrey Smagin

“…Rain gardens are efficient nature-based solutions (NBSs) for the sustainable management of surface run-off in urban areas. The functionality of a rain garden in an urban environment depends on the resistance of plant and soil components to anthropogenic stressors. …”
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Age- and severity-adjusted treatment of proximal humerus fractures in children and adolescents-A systematical review and meta-analysis. by Lisa Hohloch, Helge Eberbach, Ferdinand C Wagner, Peter C Strohm, Kilian Reising, Norbert P Südkamp, Jörn Zwingmann

“…Up to now, no evidence-based algorithm for conservative and operative treatment is available. The aim of this systematic review with meta-analysis was therefore to gather the best evidence of different treatment methods and their associated functional outcome, complication rates, rates of limb length discrepancies and radiological outcome.…”
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Comprehensive analysis of RFC4 as a potential biomarker for regulating the immune microenvironment and predicting immune therapy response in lung adenocarcinoma by Jianqing Zheng, Na Lin, Bifen Huang, Min Wu, Lihua Xiao, Bingwei Zeng

“…A high RFC4 expression level was associated with a lower TIDE score, indicating a stronger therapeutic response to immunotherapy. Functional prediction of RFC4 suggested that RFC4 mainly participated in DNA replication and repair, and reshaped the TIME.ConclusionsRFC4 proved to be a promising biomarker for tumorigenesis and could effectively predict immunotherapy response in LUAD. …”
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Psychometric properties of the Chinese version of scales of knowledge, attitude, and practice of self-care for patients with arteriovenous fistula: a translation and verification s... by Chuang Li, Chuang Li, Youbei Lin, Jiaxin Cheng, Danfeng Xu, Danfeng Xu, Lan Zhang

“…Hemodialysis remains a critical life-sustaining treatment for CKD patients, with arteriovenous fistulas (AVFs) being the most commonly used vascular access. The long-term functionality of AVFs relies heavily on patients’ self-care abilities, encompassing their knowledge of maintenance practices, appropriate attitudes toward care, and the implementation of effective self-care behaviors. …”
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Extracellular vesicles (EVs) in seminal plasma of buffalo bulls possess spermatozoa specific fertility associated proteins and enzymes by Rakesh Kumar, Mir Ahmad, Bala Subramaniam, Ankit Pal, Aditya Patel, Shiva Shiva, Vitika Chauhan, Seema Karanwal, Mukesh Bhakat, Tirtha K. Datta

“…Bull fertility is vital to productivity, sustainability, and efficient buffalo farming. The current study aims to assess the extracellular vesicles (EVs) based fertility marker in the seminal plasma of buffalo bulls. …”
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DYNAMIC OF PHYSICAL CAPACITY AND QUALITY OF LIFE AFTER HEART TRANSPLANTATION by M. A. Simonenko, A. V. Berezina, P. A. Fedotov, Y. V. Sazonova, T. M. Pervunina, T. A. Lelyavina, M. Y. Sitnikova, G. V. Nikolaev, M. L. Gordeev, M. A. Karpenko

“…Aim: to estimate physical capacity and quality of life (QoL) and defi ne factors which impact on their dynamic in recipients after heart transplantation (HTx).Materials and methods. …”
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Establishment of a Novel in vitro Model of Sepsis-Induced Myocardial Injury Using Septic Serum: A Comprehensive Comparative Study by Yang H, Feng L, Jiang Z, Deng R, Wu X, Zeng K

“…The mRNA expression profiles were analyzed to identify differentially expressed genes (DEGs), followed by functional enrichment analysis. The diagnostic utility of each model was assessed using receiver operating characteristic (ROC) analysis.Results: While LPS and TNF-α-treated cardiomyocytes exhibited similar injury features, both only partially captured the complexity of the sepsis-induced myocardial injury phenotype. …”
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Glomerular filtration rate dynamics in patients with diffuse large B-cell lymphoma during induction immunopolychemotherapy by A. S. Nozdricheva, I. B. Lysenko, N. K. Guskova, M. A. Konovalchik, A. A. Maslov, E. V. Shalashnaya

“…Aim. To study the glomerular filtration rate (GFR) dynamics during induction immunopolychemotherapy (PCT) in patients with newly diagnosed diffuse large B-cell lymphoma.   …”
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Identification and expression profile analysis of circRNAs associated with goat uterus with different fecundity during estrous cycle by Xiaolong Du, Yufang Liu, Xiaoyun He, Lin Tao, Meiying Fang, Mingxing Chu

“…During the reproductive cycle, the uterus plays a pivotal role, with its functions evolving in line with the different stages of the cycle. …”
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Unmet long-term care needs and their association with health-related quality of life among Chinese oldest-old population by Jiajun Qiao, Yiwei Qiao, Jialong Tan, Nuo Chen, Nan Peng, Zongfu Mao, Yali Zhao, Chen Chen, Yao Yao

“…Abstract Background Entering the age of 80 or 100, individuals’ functional decline and the need for assistance in daily activities increase dramatically, resulting in an inevitable increase in unmet long-term care (LTC) needs. …”
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Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization by Yingquan Zhuo, Xiaoyun Feng, Wenqi Zhang, Jun Du, Xu Sun, Xi Luo, Wei Wang, Hua Jiang, Huajian Gu

“…In vitro and in vivo experiments were performed to investigate the biological functions of CTHRC1 in WT and its effects on M2-TAMs polarization. …”
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Evaluating the Efficacy of MamaLift Plus Digital Therapeutic Mobile App for Postpartum Depression (SuMMER): Randomized, Placebo-Controlled Pivotal Trial by Shailja Dixit, Indira Malladi, Sidhartha Shankar, Amrik Shah

“…The sham control mimicked the features, functionality, and user experience of the treatment. …”
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Alkaline-Potassium Ferrate Pretreatment Promoting Acid Production Through Co-Fermentation of Waste Activated Sludge and Corn Straw by Xintian YU, Wei ZENG

“…Microbial community analysis revealed a reduction in the Shannon index, with a notable enrichment of fermentation-related functional bacteria, including Firmicutes and Bacteroidota. …”
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