Orthopedic treatment with fixed dentures taking into account the distribution and causes of defects in dental hard tissues by Yu. V. Klymiuk, Z. R. Ozhogan, L. V. Miziuk, V. M. Kryvanych, I. V. Yanishen

“…The abutment teeth had a different functional state – they were filled, had wedge-shaped defects or increased abrasion. …”
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Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

“…Hong Liu,1,* Manxue Mei,1,* Hua Zhong,2 Shuyin Lin,1 Jiahui Luo,1 Sirong Huang,1 Jiuyao Zhou1 1Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2Department of Gerontology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiuyao Zhou, Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China, Email yaoli@gzucm.edu.cn, zhoujiuyao@vip.tom.comBackground: Chronic kidney disease (CKD) is a progressive condition that arises from diverse etiological factors, resulting in structural alterations and functional impairment of the kidneys. We aimed to establish the Anoikis-related gene signature in CKD by bioinformatics analysis.Methods: We retrieved 3 datasets from the Gene Expression Omnibus (GEO) database to obtain differentially expressed genes (DEGs), followed by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, Gene Set Enrichment Analysis (GSEA) and Gene Set Variation Analysis (GSVA) of them, which were intersected with Anoikis-related genes (ARGs) to derive Anoikis-related differentially expressed genes (ARDEGs). …”
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Nitrogen cycling during an Arctic bloom: from chemolithotrophy to nitrogen assimilation by Rafael Laso-Pérez, Juan Rivas-Santisteban, Nuria Fernandez-Gonzalez, Christopher J. Mundy, Javier Tamames, Carlos Pedrós-Alió

“…Bloom dynamics are affected by nutrient availability, especially nitrogen, which is the main limiting nutrient in the Arctic. This study aimed to investigate the changes in an Arctic microbial community using omics approaches during a phytoplankton bloom focusing on the nitrogen cycle. …”
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Morphometric Analysis of the Proximal and Distal Ends of Adult Dry Femur Bone: A Cross sectional Study in the Population of North Karnataka, India by Shilpa M Bhimalli, Agamdeep Singh Bedi, Mugdha Malik, Vinod Chandgadkar, Sheetal V Pattanshetti, Daksha Dixit

“…It enhances the understanding of many other factors that influence bone, such as its strength, structural integrity, and functions. Aim: To quantify the morphometric parameters of the proximal and distal ends of the adult femur, including measurements of size, shape, and angular relationships. …”
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Maternal consumption of yoghurt activating the aryl hydrocarbon receptor increases group 3 innate lymphoid cells in murine offspring by Grégory Pimentel, Thomas Roder, Cornelia Bär, Sandro Christensen, Zahra Sattari, Cristina Kalbermatter, Ueli von Ah, Christelle A. M. Robert, Pierre Mateo, Rémy Bruggmann, Stephanie C. Ganal-Vonarburg, Guy Vergères

“…Using germ-free mice, the aim of our study was to test if maternal intake of a dairy product enriched in AhR-activating indoles produced by fermentation could boost maturation of the intestinal innate immune system in the offspring. …”
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Single-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4−related op... by Yu Yang, Yu Yang, Yujiao Wang, Xuelian Jin, Weimin He

“…Subsequently, we conducted bioinformatics analyses, including cell subpopulation segmentation and inter-group comparison, tumor cell identification, functional enrichment analysis, and pseudotime trajectory analysis. …”
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BALF editome profiling reveals A-to-I RNA editing associated with severity and complications of Mycoplasma pneumoniae pneumonia in children by Yun-Yun Jin, Yun Guo, Su-Wan Xiong, Na Zhang, Jian-Huan Chen, Feng Liu

“…By studying RNA editing changes in bronchoalveolar lavage fluid from patients with M. pneumoniae pneumonia, we aim to investigate how M. pneumoniae infection alters epigenetics and contributes to the disease severity and complications. …”
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Association of hypertriglyceridemia with risk factors for cardiovascular and renal complications in individuals with high cardiovascular risk by I. T. Murkamilov, V. V. Fomin, Zh. A. Murkamilova, I. S. Sabirov, A. I. Sabirova, Sh. E. Umurzakov, F. A. Yusupov, T. I. Maanaev, K. A. Gasanov

“…Aim. To study clinical and functional manifestations of hypertriglyceridemia and its association with risk factors for cardiovascular and renal complications in individuals with high cardiovascular risk.Material and methods. …”
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Association of early prognosis in patients with chronic heart failure with markers of renal tubulointerstitial dysfunction by V. A. Lysenko, V. V. Syvolap

“…This study included 57 patients (43.9 % men, n = 25; 56.1 % women, n = 32) with ischemic CHF, stage II A–B, II–IV functional class per NYHA. Among them, 49.1 % (n = 28) had sinus rhythm, and 50.9 % (n = 29) had atrial fibrillation. …”
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Nuclear keratin 6A upregulates human papillomavirus oncogene expression through TEAD1 interaction by Tomoya Miyamura, Seiichiro Mori, Mamiko Onuki, Akihiko Sekizawa, Koji Matsumoto, Iwao Kukimoto

“…K6A was detected in the nuclear fraction of cervical cancer cells with a functional bipartite nuclear localization signal in its N-terminus. …”
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Gamified mHealth System for Evaluating Upper Limb Motor Performance in Children: Cross-Sectional Feasibility Study by Md Raihan Mia, Sheikh Iqbal Ahamed, Samuel Nemanich

“…We developed MoEvGame, a mobile health (mHealth) gamification software system for the iPad, as a potential advanced technology to assess UL motor functions. ObjectiveThis feasibility study examines whether MoEvGame can assess children’s whole-limb movement, fine motor skills, manual dexterity, and bimanual coordination. …”
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Smartphone Application–Based Voice and Speech Training Program for Parkinson Disease: Feasibility and Satisfaction Study With a Preliminary Rater-Blinded Single-Arm Pretest and Pos... by Sol-Hee Lee, Jiae Kim, Han-Joon Kim

“…Each session included 5 stages: breathing, oral motor exercises, loudness, prosody, and functional speaking. The training program consisted of 20 sessions, with participants completing 1 session per day, 4 days per week. …”
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Clinical value of complex ambulatory monitoring of blood pressure and arterial rigidity in elderly patients by M. A. Markova, E. E. Tyulkina, Yu. V. Kotovskaya, Zh. D. Kobalava

“…Sixteen patients had Functional Class II-III angina (n=16), and 32 received antihypertensive therapy. 24-hour BMP and PWT parameters were measured. …”
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Peripandemic outcomes of infants treated for sentinel congenital heart diseases in England and Wales by Massimo Caputo, Christina Pagel, Sonya Crowe, John Nolan, Deborah A Lawlor, Qi Huang, Rodney CG Franklin, Kate L Brown, Ferran Espuny-Pujol

“…The casemix was hypoplastic left heart syndrome (195; 3.9%), functionally univentricular heart (180; 3.7%), transposition (610; 13.5%), pulmonary atresia (290; 5.9%), atrioventricular septal defect (590; 12.1%), tetralogy of Fallot (820; 16.7%), aortic stenosis (225; 4.6%), coarctation (740; 15.1%) and ventricular septal defect (1200; 24.5%).Compared with prepandemic, there was no evidence for delay in treatment procedures in transition, restrictions or postrestrictions eras. …”
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Improving the quality of theoretical training of cadets with the help of information and communication technologies by V. V. Bulgakov

“…Freely available computer programs, designed for theoretical training and control, often have limitedfunctionality, and programs with more functionality do not allow organizing training in accordance with the security requirements for personal and service data, established in the Ministry of Emergency Situations of Russia.Materials and methods. …”
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The Burden of COPD with Type 2 Inflammation in North-West Continental Europe by Sandelowsky H, Løkke A, Kocks JWH, Grøttum HS, Bakke PS, Vasankari T

“…COPD is primarily understood to be a functional disorder with chronic airway obstruction, yet there are several underlying inflammatory pathways. …”
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Vulvovaginal atrophy: modern approaches to diagnostics and management by V. H. Siusiuka, N. V. Avramenko, M. I. Pavliuchenko, M. Yu. Serhiienko, A. O. Kniazieva

“…The aim of the review is to analyze the latest data on the current state of diagnosis and management of a common benign vulvar and vaginal disease in postmenopausal women – atrophic vulvovaginitis. …”
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Patient–Health Care Professional Communication via a Secure Web-Based Portal in Severe Mental Health Conditions: Qualitative Analysis of Secure Messages by Eva Meier-Diedrich, Carolyn Turvey, Jonas Maximilian Wördemann, Justin Speck, Mareike Weibezahl, Julian Schwarz

“…Regarding the purposes of SM, 4 core functions of SM were identified: reporting and feedback, interpersonal uses, intrapersonal uses, and organizational uses. …”
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Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry by Safaa Salah El-Din Taha, Osama Abd El-Hamid Ibrahim, Einas Hamed El-Shatoury, Amany Mohamed El-Deeb, Hayam Abd El-Naby Sayed

“…UF-Cheese permeate is a dairy byproduct characterized by high lactose content, generated through the ultrafiltration process that separates proteins and fats from milk. The aim of this study was to use UF-Cheese permeate as a medium for promoting bacterial growth to producing the β-galactosidase (lactase) enzyme, which is beneficial for individuals with lactose intolerance in manufactured dairy products. …”
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The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation. by Mark Jeffries, Nde-Eshimuni Salema, Libby Laing, Azwa Shamsuddin, Aziz Sheikh, Anthony Avery, Antony Chuter, Justin Waring, Richard N Keers

“…Engagement between stakeholders was considered important for the intervention in ensuring prescribers continued to utilise its functionality. Sustained implementation might be enhanced by careful profile management of the suite of alerts in the system. …”
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