The Reconstruction of Various Complex Full-Thickness Skin Defects with a Biodegradable Temporising Matrix: A Case Series by Julie van Durme, Thibaut Dhont, Ignace De Decker, Michiel Van Waeyenberghe, Kimberly De Mey, Henk Hoeksema, Jozef Verbelen, Petra De Coninck, Nathalie A. Roche, Phillip Blondeel, Stan Monstrey, Karel E. Y. Claes

“…Two patients were lost to follow-up, while the remaining four had excellent aesthetic and functional outcomes with good-quality scars. Conclusions: Within the limits of this small and heterogeneous case series, the BTM appears to be a promising option for the reconstruction of complex FTSDs of varying etiologies. …”
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Assessing the Impact of the Prostate Cancer Patient Empowerment Program (PC-PEP) on Relationship Satisfaction, Quality of Life, and Support Group Participation: A Randomized Clinic... by Cory Burgher, Gabriela Ilie, Ross Mason, Ricardo Rendon, Andrea Kokorovic, Greg Bailly, Nikhilesh Patil, David Bowes, Derek Wilke, Cody MacDonald, Markos Tsirigotis, Calvin Butler, David Bell, Jesse Spooner, Robert David Harold Rutledge

“…Outcomes were assessed using the Dyadic Adjustment Scale (DAS) and the Functional Assessment of Cancer Therapy–Prostate (FACT-P). …”
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Prevalence of hepatitis B virus infection and associated factors among students living on campus in South-eastern Gabon by Augustin Mouinga-Ondeme, Moussa Yaro, Guy-Roger Ndong Atome, Madeleine Meba, Neil Michel Longo-Pendy, Roseanne Mounanga Mourimarodi, Christ Eddy Ognari Ayoumi, Abdoulaye Diane, Jeordy Dimitri Engone-Ondo, Eldridge Fedricksen Oloumbou, Ivan S. Mfouo Tynga

“…Abstract Background The Hepatitis B-virus is the etiological agent of an infection that affects liver functions and potentially causes disorders. Approximately, 300 million people are living with acute or chronic HBV-infections worldwide, and only a fraction of them have access to medical care. …”
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Transcriptomic analysis of melatonin-mediated drought stress response genes in alfalfa during germination period by Xiaoxia Zhang, Wenxuan Zhu, Zirui Liu, Xiangling Ren, Yingao Li, Guomin Li, Jingzhuo Wang, Xiaoyan Zhu, Yinghua Shi, Chengzhang Wang, Defeng Li, Hao Sun

“…Based on transcriptomics and physiological index detection, this study aimed to explore the regulatory mechanism of melatonin in alleviating drought stress during alfalfa germination. …”
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Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease by Guo-Lin Miao, Wen-Xi Zhang, Yi-Tong Xu, Yi-Ran Liu, Ping-Ping Lai, Jia-Bao Guo, Gong-Lie Chen, Jing-Xuan Chen, Zi-Hao Zhou, Yan-Wei Li, Chong Zhang, Yang Ding, Lian-Xin Zhang, Yu-Fei Han, Jin-Xuan Chen, Jing-Dong Wu, Yin-Qi Zhao, Si Mei, Yang Zhao, Yuan-Wu Ma, Ling Zhang, Wei Huang, Dong-Yu Zhao, Er-Dan Dong, Yu-Hui Wang, Xun-De Xian

“…Abstract Background Kinesin family member 13B (KIF13B), a crucial motor protein, exerts multiple cellular biological functions. However, the implication of KIF13B in metabolic dysfunction-associated fatty liver disease (MAFLD) has not been explored yet. …”
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Association of bone fracture type and degree of callus formation with leptin concentration in children with long bone fractures by Paunović Zoran, Stanojević Ivan, Abazović Džihan, Rakić Mia, Stanković Nikola, Đukić Mirjana, Milutinović Sanja, Starčević Srđan, Šupić Gordana, Vojvodić Danilo, Jović Milena, Marić Dušan

“…Background/Aim. Recent studies indicate that adipokines have an important role in bone physiology and pathology. …”
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Regional Design by Verena Balz

“…Aims and secondary aims are reflected in the following research questions: How do the interrelations between regional design and spatial planning influence the performances of design? …”
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Research Framework and Anticipated Results of Key Technologies for Distributed Certificate-less Network Identity Systems by ZHANG Xiaosong, CAO Sheng, LU Tianbo, YANG Kun, GUI Xun, XIE Guotao, NIU Weina

“…Lastly, in large-scale distributed IoT identity authentication applications and validation, a lightweight public key identification model based on national cryptographic standards was designed, achieving breakthroughs in GBA protocol integration and AI-driven certificate-less authentication, with evaluation tools developed to simulate IoT networks with at least 300 nodes.Conclusions and ProspectsThis research aims to address challenges such as the design of authentication architectures, efficient key management, acceleration of access processes, and parallel execution of contracts, ensuring functionalities such as data allocation on demand and anonymous identity verification, while guaranteeing user privacy, security, and supporting dynamic collaborative computing for massive terminals. …”
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Design, Synthesis, and Biological Evaluation of a Novel [¹⁸F]AlF-H₃RESCA-FAPI Radiotracer Targeting Fibroblast Activation Protein by Qingyu Zhang, Zhoumi Hu, Haitao Zhao, Fuqiang Du, Chun Lv, Tukang Peng, Yukai Zhang, Bowu Zhang, Jianjun Liu, Cheng Wang

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The effect of non-surgical periodontal therapy on glycemic control in Indian diabetics with periodontal disease – A systematic review and meta-analysis by Komal K. Ghadge, Sharath K. Shetty, Anita Kulloli, Santosh Martande, Vini Mehta, D. Gopalakrishnan, Ankita Mathur, Luca Fiorilla

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Contraindications to Whole-Body Cryostimulation (WBC). A position paper from the WBC Working Group of the International Institute of Refrigeration and the multidisciplinary expert... by Paolo Capodaglio, Paolo Capodaglio, Angelo Alito, Benoit Michel Duguè, Romain Bouzigon, Romain Bouzigon, Giovanni Lombardi, Giovanni Lombardi, Elzbieta Dorota Miller, Federica Verme, Giuseppe Modaffari, Paolo Piterà, Ewa Ziemann, Jacopo Maria Fontana

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Study of anti-inflammatory, antioxidant, antimicrobial and mineralizing effects of an N-isopropenylimidazole zinc metal complex derivative in experimental endodontic-periodontal le... by Pavel A. Galenko-Yaroshevsky, Ivan I. Pavlyuchenko, Olga V. Shelemekh, Boris A. Trofimov, Lidiya N. Parshina, Viktor L. Popkov, Svetlana A. Demyanenko, Oleg V. Tsymbalov, Andrey V. Zadorozhniy, Anait V. Zelenskaya, Irina B. Nektarevskaya, Alina V. Sergeeva, Nikolay E. Korovaykin, Svetlana A. Lebedeva

“…This necessitates search for and development of new molecules with a wide range of therapeutic effects aimed to block the infectious and inflammatory process and to restore the functional ability of teeth in EPLs as much as possible (depending on a lesion severity). …”
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Youth co-production for sustainable engagement and empowerment in health (YiPEE): protocol for a cluster-randomised controlled trial of an intervention for mental health promotion... by Josefien van Olmen, Pilvikki Absetz, Mark Tomlinson, Carina King, Edwin Wouters, Josefien van Olmen, G J Melendez-Torres, Jeroen De Man, Stefan Swartling Peterson, Suresh Kumar, Mariam Claeson, Monika Martens, Frances Mathews, Christina A Laurenzi, Yoona Kim, Yeukai Chideya, Maria Niemi, Vijaya Raghavan, Jill Åhs, Anu Linnansaari, Fredric Azariah, Moitreyee Sinha, Upasana Sharma, Orlaith O’Sullivan, Yoo Na Kim, Akshaya Rajesh, Samyukta Saravanan, Nivetha Vasanthan, N P Haritha, Lander Willem, Jeroen de Man, Christina Laurenzi, GJ Melendez Torres, Matt Hughsam, Maureen Gikonyo, Joyce Arita

“…Character education-focused interventions are effective for improving adolescent psychosocial functioning and mental well-being. Therefore, an intervention that focuses on developing these strengths and is delivered within a school environment, through an adolescent-informed approach using creativity-focused components, has the potential to improve adolescent mental health and well-being.Methods and analysis This protocol describes the YiPEE cluster-randomised controlled trial with concurrent mixed-methods process evaluation and economic evaluation, which aims to determine the impact of a multilevel multicomponent intervention in schools in Chennai, Tamil Nadu, India. …”
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Using computational pharmacology and experimental verification to decode mechanism of Qing-Wei-San in treating periodontitis by Yanhong Liu, Wenqi Li, Jingxiao Chen, Yi Li, Jieqi Cai, Yongxi Luo, Jiahao Lin, Lu Chen, Aiping Lu, Daogang Guan, Huiyong Xu

“…Abstract Objective This study aims to identify the bioactive components of Qing-Wei-San (QWS) for treating periodontitis and to uncover their mechanisms using computational pharmacology. …”
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Exploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation by Xin-Yu Li, Kun Li, Yi-Han Wei, Wen-Kai Yu, Jing-Hao Wu, Kai Gao, Wen-Jun He, Peng-Peng Niu, Chan Zhang, Yu-Nan Cheng, Yu-Sheng Li

“…We explored the biological functions of these genes through immune cell infiltration, metabolic and Hallmark pathway analyses, and clinical correlation analysis. …”
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Engineered <i>Escherichia coli</i> Nissle 1917 Expressing IGF1 and FGF19 Reduce Liver Fat Accumulation and Restore Microbial Equilibrium in a Metabolic Dysfunction-Associated Steat... by Johnson Lok, Valeria Iannone, Carlos Gómez-Gallego, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer, Marjukka Kolehmainen, Hani El-Nezami

“…This may be a combined effect of hormones and EcN, as a probiotic, thereby improving gut endocrine and immune functions.…”
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ROC analysis data and predictors of rehabilitation effectiveness in patients with type 2 diabetes mellitus by T.H. Bakaliuk, N.R. Makarchuk, H.O. Stelmakh, V.I. Pankiv, L.B. Pavlovych, O.D. Bilous, I.I. Kamyshna

“…Effective rehabilitation for such patients contributes to the improvement of their functional status, reduces the risk of complications, and enhances the overall prognosis. …”
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Non-invasive device to alleviate symptoms in people living with Parkinson’s: study protocol for a multicentre phase II double-blind randomised controlled trial by David Gallagher, Cristina Simonet, Alexandra Zirra, Alastair Noyce, Caroline Budu, Ellen Camboe, Viktoria Azoidou, Essa Bhadra, Kira Rowsell, Kamalesh Dey, Corrine Quah, Thomas Boyle

“…Effectiveness will be evaluated at the same time points using movement tests (MDS-UPDRS Part III, Functional Gait Assessment, Timed Up and Go in isolation and with dual tasking and two keyboard-based typing tests—Bradykinesia Akinesia Incoordination and Digital Finger Tapping), with video recordings. …”
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Right ventricular outflow tract morphology and its clinical significance for invasive procedures by Marcin Jakiel, Rafał Jakiel, Jakub Batko, Edyta Dyngosz, Maria Kurek, Karolina Gutkowska, Jakub Hołda, Filip Bolechała, Marcin Strona, Mateusz K. Hołda

“…Abstract We aimed to evaluate in detail the right ventricular outflow tract (RVOT) morphology to enhance clinical procedures performed within this area. …”
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A new method for dealing with collider bias in the PWP model for recurrent events in randomized controlled trials by Chen Shi, Jia-Wei Wei, Zi-Shu Zhan, Xiao-Han Xu, Ze-Lin Yan, Chun-Quan Ou

“…However, the Prentice, Williams, and Peterson (PWP) model disrupts the randomness of the risk set for subsequent recurrent events other than the first and consequently introduces bias in estimating effects. This study aimed to propose a weighted PWP model, evaluate its statistical performance, and assess the potential consequences of using common practices when each recurrence has different baseline hazard functions. …”
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