A Comparative Study of Taylor Spatial Frame and Monolateral External Fixator for Treating Infected Tibial Defects With Concomitant Soft Tissue Loss by Zhiming Zhao, Guoqi Ji, Chengkuo Cai, Hengsheng Shu, Weiguo Xu

“…ABSTRACT Objective The management of infectious tibial defects with concomitant soft tissue loss (ITD‐STL) continues to pose substantial clinical challenges in orthopedic practice. This study aimed to compare the clinical efficacy of the Taylor Spatial Frame (TSF) versus the Monolateral External Fixator (MEF) in achieving bone and soft tissue reconstruction for ITD‐STL. …”
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A Retrospective, Comparative Study on Infinity Ankle Replacements vs Ankle Fusions by John Steyn MD, FRCSC, Murray J. Penner MD, FRCSC, Alastair S.E. Younger MB ChB, ChM, FRCSC, Kevin Wing MD, FRCSC, Andrea Veljkovic MD, MPH, BComm, FRCSC, Hooman Sadr MD, FRCSC, Oliver Gagne MD, FRCSC

“…While ankle fusion has traditionally been the treatment of choice, it often impairs ankle functionality, and can increase the development of painful hindfoot arthritis. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…This comorbidity can significantly impair the quality of life, particularly in adolescents with high-functioning ASD, where the prevalence reaches 41.98%. …”
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Septal alcohol ablation in patients with hypertrophic cardiomyopathy and left ventricular outflow tract obstruction by Mariia S. Nozdriakova, Dmitrii A. Zalyubovsky, Dmitriy S. Maznev, Dmitrii S. Evdokimov, Aleksei S. Sergeev, Eugene A. Shloydo

“…A statistically significant improvement in New York Heart Association functional class was observed — from class III–IV to class I–II (p=0.0009). …”
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Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling by Hyun-Jee Han, Marcos Rubio-Alarcon, Thomas Allen, Sunwoo Lee, Taufiq Rahman

“…This study aims to establish a foundation for future research, leading to biological experiments with focused gene-sets derived from our findings. …”
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Hemodynamic and Genetic Associations with the Risk of Idiopathic Pulmonary Arterial Hypertension Development in an Ethnic Cohort of Kazakhs by Dana Taizhanova, Togzhan Nurpissova, Gulshara Abildinova, Tamilla Martynyuk, Nazgul Kulmyrzayeva, Elena Zholdybayeva

“…Materials and methods: A total of 53 patients of only Kazakh nationality with IPAH participated in the study. Clinical, functional, and hemodynamic characteristics, as well as the outcome of the disease, were compared among carriers and non-carriers of the BMPR2 mutation. …”
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Efficacy and safety of IL-23 p19 inhibitors in the treatment for inflammatory bowel disease: a systematic review and meta-analysis by Shuhan Wang, Hui Sun, Qian Wang, Han Xiao

“…The overall performance of IL-23 p19 inhibitors for the treatment of IBD was evaluated by the systematic review and meta-analysis in this study.ObjectiveThe objective of this study was to combine the multiple indicators to accurately evaluate the efficacy and safety of IL-23 p19 inhibitors, aimed to offer an insight into the development of clinical physicians’ medication.MethodsA comprehensive literature review on PubMed, Embase, Web of Science, and Cochrane Library until June 2024 was conducted in this study, which mainly focused on the randomized controlled trials (RCTs) to evaluate the IL-23 p19 inhibitors within adult patients with UC or CD. …”
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Simple and Discriminatory Reaction Times in Preovulatory and Postovulatory Phases of Menstrual Cycle in Healthy Young Females: A Cross-sectional Study by Hemalatha Manjeshwara, V Suganthi, Amudharaj Dharmalingam, Milind V Bhutkar, Gopinath Manavazhagan

“…Introduction: The menstrual cycle plays a significant role in the functioning of the cardiovascular and central nervous systems. …”
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Three-dimensional finite element analysis of occlusal stress on maxillary first molars with different marginal morphologies restored with occlusal veneers by Qing Chen, Siyang Luo, Yujuan Wang, Zhu Chen, Ying Li, Maohua Meng, Yamei Li, Nan Xiao, Qiang Dong

“…The stresses of the SFL and CFL is concentrated primarily at the edge position below the functional cusp, resulting in relatively low adhesive stress. …”
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Outcomes of oncologic arthroplasty in children and adolescents with malignant limb tumors: a systematic review by Vyacheslav I. Zorin, Sergei V. Vissarionov, Alexandr Y. Makarov, Timofey S. Rybinskikh, Kristina N. Rodionova

“…Currently, limb-sparing oncologic arthroplasty is the preferred surgical approach for treating limb sarcomas in children. The aim of the systematic review is to analyse the outcomes of oncologic arthroplasty in children and adolescents. …”
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SURGICAL TREATMENT OF CHEST INJURIES WITH COMBINED TRAUMA AND POLYTRAUMA: A COMPARATIVE ANALYSIS OF THE STRUCTURE AND COMPONENTS OF THE THORACIC INTERVENTION PHASE (MESSAGE ONE) by Serhii I. Panasenko, Serhii O. Guriev, Volodymyr V. Nehoduiko, Nizar R. Kerbazh

“…The system of anatomical and functional prediction of injury course did not influence the determination of diagnostic and therapeutic tactics for correction of chest injuries in the group of polytrauma casualties. …”
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Quantitative assessment of the potential of retail outlets by K. A. Lychagin

“…Today  the paradigm  of open complex systems is used to simulate and analyze the mechanisms and processes of interaction  of agents in the market  environment. The main modern functioning of enterprises are corporate information systems,  telecommunication networks, Internet  technologies,  mobile communication systems,  Big Data,  technologies of intellectual  analysis, forecasting and machine  learning. …”
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Innate Immunity Stimulation during the COVID-19 Pandemic: Challenge by Parvulan by Beniamino Palmieri, Antonio Manenti, Francesca Galotti, Maria Vadalà

“…The main efficacy endpoints, as assessed by the SF-36 questionnaire are: significant improvements in the mental and physical role functioning score (p<0.02), better general health; social role performance (p<0.02), vitality (p<0.03), and a significant pain reduction (p<0.03). …”
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Psychometric evaluation of the Chinese version of the Patient Self-Advocacy Scale using classical test theory and item response theory by Jialu Cui, Jing Wang, Ailin Yue, Jiayan Cao, Zhijie Zhang, Baoxin Shi

“…The Wright map showed good matching between item difficulty and person ability. Differential item functioning (DIF) analysis revealed no significant differences across gender. …”
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High expression of G-protein signaling modulator 2 in hepatocellular carcinoma facilitates tumor growth and metastasis by activating the PI3K/AKT signaling pathway by Xiao-Qin He, Yue-Feng Zhang, Jia-Jun Yu, Yuan-Yuan Gan, Na-Na Han, Mei-Xia Zhang, Wei Ge, Jun-Jian Deng, Yong-Fa Zheng, Xi-Ming Xu

“…The aim of this study was to investigate the role of G-protein signaling modulator 2 in the carcinogenesis and progression of hepatocellular carcinoma. …”
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Health effects and mediating mechanisms of smart wearable devices on older people: evidence from China by Enkai Guo, Enkai Guo, Enkai Guo, Shiyi He, Shiyi He, Shiyi He, Lan Zheng, Lan Zheng, Lan Zheng

“…To maximize benefits, we propose a dual-path optimization strategy: (1) Develop age-appropriate functions and use methods to improve device accessibility among older adult people, and (2) Generate a personalized exercise prescription for the older people to promote regular physical activity and exercise habits to improve their health level.…”
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The seven deadly sins: measuring overvaluation of social media with the Plan-net 25 scale by Víctor Ciudad-Fernández, Alfredo Zarco-Alpuente, Tamara Escrivá-Martínez, Elena Gomis-Vicent, Begoña Espejo, Óscar Lecuona, José C. Perales, Olatz Lopez-Fernandez, Rosa Baños

“…Abstract Background Problematic social media use refers to the excessive and maladaptive use of social media platforms, which negatively affects personal, social, and professional functioning. Although linked to mental health issues such as depression, anxiety, and loneliness, the underlying mechanisms remain unclear. …”
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Effect of GR24 on the growth and development of licorice under low phosphorus stress by Yuting Jing, Man Li, Yong Wu, Chengming Zhang, Chengshu Qiu, Hengming Zhao, Li Zhuang, Hongling Liu

“…Transcriptome analysis revealed differential gene, with 137 and 270 genes up-regulated and 77 and 294 genes down-regulated in the P3 and P2 treatments, respectively. GO functional enrichment identified 132 and 436 differentially expressed genes for P3 and P2 respectively, while KEGG pathways were predominantly enriched in plant-pathogen interactions and phenylpropanoid biosynthesis. …”
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ANALISIS STAKEHOLDERS DALAM PENGEMBANGAN PROGRAM DIKLAT DI BALAI DIKLAT APARATUR KEMENTERIAN KELAUTAN DAN PERIKANAN STAKEHOLDERS ANALYSIS IN DEVELOPMENT OF TRAINING PROGRAM ON TRAI... by Yudistira Adi Nugroho

“…One of the contributing factors is the development of training programs in both technical training and functional training have not been fully implemented. …”
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A spatial matrix factorization method to characterize ecological assemblages as a mixture of unobserved sources: An application to fish eDNA surveys by Letizia Lamperti, Olivier François, David Mouillot, Laëtitia Mathon, Théophile Sanchez, Camille Albouy, Loïc Pellissier, Stéphanie Manel

“…Abstract Understanding how ecological assemblages vary in space and time is essential for advancing our knowledge of biodiversity dynamics and ecosystem functioning. Metabarcoding of environmental DNA (eDNA) is an efficient method for documenting biodiversity changes in both marine and terrestrial ecosystems. …”
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