Biodiversity of colon microbiota in residents of Arkhangelsk by N. N. Kukalevskaya, T. A. Bazhukova, A. M. Grjibovski, N. V. Davidovich, S. N. Pisareva, M. A. Sabanaev

“…Study showed common features among all residents of this region – a deficiency of obligate representatives of microflora: lactobacilli, enterococci, a reduced number of bifidobacteria, and functional Escherichia coli. Also, temporary residents had a higher number of B. thethaiotaomicron (p=0.005), Ruminococcus spp. …”
Get full text

High residual platelet reactivity during dual antiplatelet therapy, found by optical aggregometry and the rate of atherothrombotic complications after coronary artery stenting in p... by N. F. Puchinyan, N. V. Furman, P. V. Dolotovskaya, L. L. Malinova

“…Patients after PTCA and during DAT were included into the study. Evaluation of the functional activity of platelets by optical aggregometry was performed in all patients at baseline. …”
Get full text

COMPARATIVE ANALYSIS OF CYTOKINE PRODUCTION BY BLOOD IMMUNOCOMPETENT CELLS AND TUMOR IN DIFFERENT AGE GROUPS OF PATIENTS WITH INVASIVE DUCTAL CARCINOMA by T. A. Kunts, E. S. Mikhaylova, I. O. Marinkin, N. A. Varaksin, A. I. Autenshlyus

“…In both groups of patients, there was an increase of IL-6, IL-8, IL-10, IL-17, IL-18, IL-1ra, G-CSF, GM-CSF and VEGF concentrations in tumor supernates and its microenvironment, when compared with the production of cytokines by blood cells, thus indicating to high functional activity of tumor together with its microenvironment. …”
Get full text

Metabolomics analysis of children with spastic cerebral palsy: a case–control study by Özlem Tezol, Sıddika Songül Yalçın, Tuba Reçber, Anıl Yirün, Aylin Balcı Özyurt, Çetin Okuyaz, Pınar Erkekoğlu, Emirhan Nemutlu

“…Abstract Background Spasticity, pain, fatigue and other secondary consequences of spastic CP may lead to metabolic alterations. The aim of this study was to analyze the plasma metabolomic profiles of children with spastic CP and compare these with typically developing controls. …”
Get full text

Resin Composite Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler for Non-Carious Cervical Lesions: A Double-Blinded, Randomized, Split-Mouth Clinical Trial by Adam Lowenstein, Carlos Fernando Mourão, Mabi L. Singh, Sarah E. Pagni, Ronald D. Perry, Gerard Kugel

“…Evaluations were based on the Hickel criteria, covering esthetic, functional, and biological properties, with comparisons made using the Wilcoxon signed-rank test. …”
Get full text

Reduction and outcome of posterior pilon fractures with intercalary fragments: a retrospective cohort study comparing the transfibular and posteromedial approaches by Li Ying, Can Yao, Bin Wang, Junbo Liang, Guofu Chen

“…The surgical duration, number of intraoperative fluoroscopies, and postoperative complications were recorded. Functional outcomes were assessed using the Foot and Ankle Outcome Score (FAOS), Foot and Ankle Ability Measure (FAAM), and Short Form-36 (SF-36) score at last follow-up. …”
Get full text

Validación experimental de un Observador de Alta Ganancia Reconfigurable para una columna de destilación by M. Heras Cervantes, A.C. Téllez Anguiano, M.C. García Ramírez, C.M. Astorga Zaragoza, E. Reyes Archundia

“…The main idea of the observer is the continuous reconfiguration of the observer gain in order to reduce the estimation error at every moment, thus achieving a faster convergence of the observer to the actual response of the system. The aim of this work is to verify the functionality of this observer by its online experimental validation in a distillation pilot plant process. …”
Get full text

Factors Influencing the Intentions of Patients With Inflammatory Rheumatic Diseases to Use a Digital Human for Medication Information: Qualitative Study by Lex L Haegens, Victor J B Huiskes, Bart J F van den Bemt, Charlotte L Bekker

“…A digital human, which is an embodied conversational agent, could provide medication-related information in a time- and place-independent manner to support patients in preventing and decreasing DRPs. ObjectiveThis study aims to identify factors that influence the intention of patients with IRDs to use a digital human to retrieve medication-related information. …”
Get full text

Reinforcement of epoxy polymers with hydride-silylated fumed silica by P. O. Kuzema, D. L. Starokadomsky, O. O. Tkachenko, V. A. Tertykh

“…Chemical modification of silica surface enlarges its functional capabilities. In particular, silica with grafted silicon hydride groups was found to be active in the processes of hydrosilylation of alkene and alkyne bonds in monomers during their polymerization, resulting in the formation of reinforced polymeric composites. …”
Get full text

Change in adipose tissue characteristics and lipid metabolism in natural grazing Mongolian cattle with age by Xueting Yu, Lu Chen, Xige He, Yunfei Han, Yajuan Huang, Rina Sha, Gerelt Borjigin

“…Objective This study aimed to elucidate the lipid composition, characteristics, and metabolic mechanisms of subcutaneous adipose tissue (SAT) in natural grazing Mongolian cattle during its development. …”
Get full text

First-line Nurse Managerial Competence and Its Influencing Factors in Public Jordanian Hospitals by Abdulkareem S. Iblasi, Samer Makahleh, Yupin Aungsuroch, Joko Gunawan, I Gede Juanamasta

“…Background: First-line Nurse Managers (FLNMs) occupy pivotal positions within healthcare systems and are responsible for various administrative and caregiving functions. While FLNMs are integral to efficient healthcare services, their competencies and the factors influencing them still need to be explored in Jordan. …”
Get full text

Prognostic analysis of bladder cancer with neddylation-related genes by Huang Xiaolong, Deng Min, Zhang Sizhou, Hu Daorong, Pan Juncheng, Wang Yanjian, Li Jie Gu Hong, Zheng Ji, Wu Qingjian

“…Additionally, a protein–protein interaction (PPI) network, gene set enrichment analysis (GSEA), and BLCA single-cell sequencing data were utilized to explore the functional roles of hub genes in BLCA and their impact on biological pathways. …”
Get full text

Design of a Non-Destructive Seed Counting Instrument for Rapeseed Pods Based on Transmission Imaging by Shengyong Xu, Rongsheng Xu, Pan Ma, Zhenhao Huang, Shaodong Wang, Zhe Yang, Qingxi Liao

“…Human–machine interaction software based on PyQt5 was developed, integrating functions such as communication between upper and lower machines, image acquisition, storage, and processing. …”
Get full text

EFFECT OF DEXAMETHASONE ON INTERFERON-α-INDUCED DIFFERENTIATION OF MONOCYTES TO DENDRITIC CELLS by Yu. D. Kurochkina, O. Yu. Leplina, M. A. Tikhonova, T. V. Tyrinova, E. V. Batorov, A. E. Sizikov, A. A. Ostanin, E. R. Chernykh

“…However, sensitivity of these DCs to tolerogenic effect of glucocorticoids has not been previously investigated. The aim of this study was to investigate the effect of dexamethasone upon maturation and functions of interferonalpha-induced DCs (IFN-DC) derived from healthy donors. …”
Get full text

The effect of protein intake levels on early postoperative outcomes following impacted mandibular third molar removal: a pilot study by Canseda Avağ, Merve Safa Avağ, Özgür Sakarya, Attila Vural

“…Abstract Background This study aimed to evaluate the effect of protein intake on early wound healing following the surgical removal of impacted mandibular third molars, and to explore its associations with postoperative outcomes such as trismus, edema, pain, and oral health-related quality of life. …”
Get full text

Chemical research of lipophilic fractions of sickle alfalfa herbs by S. V. Kovalev

“…In this regard, a comprehensive study of advanced plant of flora of Ukraine to increase the assortments of herbal remedies is an urgent problem. The aim of this work was to obtain and chemical research of lipophilic fractions of sickle alfalfa herbs. …”
Get full text

CARDIAC REMODELLING AND CLINICAL PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE AND COMPLETE LEFT BUNDLE BRANCH BLOCK by B. Ya. Bart, V. N. Larina, M. S. Brodskyi

“…Aim: To investigate echocardiography (EchoCG) parameters and clinical prognosis in elderly patients with chronic heart failure (CHF) and complete left bundle branch block (LBBB). …”
Get full text

An exploratory analysis of longitudinal artificial intelligence for cognitive fatigue detection using neurophysiological based biosignal data by Sameer Nooh, Mahmoud Ragab, Rania Aboalela, Abdullah AL-Malaise AL-Ghamdi, Omar A. Abdulkader, Ghadah Alghamdi

“…Abstract Cognitive fatigue is a psychological condition characterized by opinions of fatigue and weakened cognitive functioning owing to constant stress. Cognitive fatigue is a critical condition that can significantly impair attention and performance, among other cognitive abilities. …”
Get full text

Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…This work compares a novel DL model using structural connectivity (namely, BC-GCN-SE adapted from functional connectivity tasks) with an established model using structural magnetic resonance imaging (MRI) scans (namely, ResNet18). …”
Get full text

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer by Wu Ning, Wenqing Jia, Jingyuan Ning, Lei Zhou, Zongze Li, Lin Zhang, Xin Song

“…Furthermore, molecular docking revealed that the targeted agent abemaciclib effectively binds HOXC6, with both cellular and animal experiments confirming its ability to inhibit CRC cell functions and significantly reduce tumor burden in nude mice.DiscussionThis study establishes the first single-cell-resolution molecular classification system for CRC, delineates the mechanistic link between EMT subtypes and metastatic progression, and identifies HOXC6 as a novel therapeutic vulnerability. …”
Get full text