IL7R, GZMA and CD8A serve as potential molecular biomarkers for sepsis based on bioinformatics analysis by Jin Li, Lantao Wang, Bin Yu, Jie Su, Shimin Dong

“…The Metascape database was used for functional enrichment analysis and was used to found the differential gene list. …”
Get full text

Metabolic characterization of selected probiotic consortia during gluten and wheat bread simulated digestion by Mirco Vacca, Giuseppe Celano, Olga Nikoloudaki, Bodo Speckmann, Francesco Maria Calabrese, Marco Gobbetti, Maria de Angelis

“…Due to the high incidence of gluten-based disorders, the present work aims to deeply explore the metabolism of two selected microbial consortia (MCs) during gluten digestion under simulated gastrointestinal conditions. …”
Get full text

DAILY CHANGES OF CENTRAL HEMODYNAMICS IN PATIENTS WITH CHRONIC HEART FAILURE WITH NIGHT-TIME DYSPNOEA ATTACK by S. A. Dovgolis, I. G. Fomina

“…Aim. To study daily changes of central hemodynamics (CHD) in patients with chronic heart failure (CHF) and the effects of therapy. …”
Get full text

Heterogeneity of Antibiotic-Resistant Isolates of Listeria Monocytogenes Isolated from Food Products in Moscow by Yu. V. Mikhailova, A. D. Molchanov, A. A. Shelenkov, M. A. Tyumentseva, K. S. Karbyshev, A. I. Tyumentsev, A. E. Egorova, N. G. Kulikova, I. N. Manzenyuk, V. G. Akimkin

“…Listeria monocytogenes is a ubiquitous bacterium that causes listeriosis, which represents a widespread infectious disease currently inflicting great damage to livestock production and posing a serious threat to human health.Aim. To analyze the population structure and assess the pathogenic potential of Listeria monocytogenes isolates isolated on the territory of the Russian Federation.Materials and methods. …”
Get full text

The Complication Of Decrease In Aorto-Mesenteric Angle And Distance Its Diagnosis And Treatment: Case Report by O. V. Galimov, V. O. Khanov, H.M. H. Karkhani, Sh. Bhawna, T. R. Ibragimov

“…In the present clinical case due to the given combination of methods we can assess functional state of the stomach and duodenum, clearly visualize not only the organs topography but also estimate the aorto-mesenteric angle and distance, which can further determine the type and tactics of initial stage treatment, which we decided to perform surgery (laparoscopic Strong’s operation). …”
Get full text

Electronic Measurement-based care (eMBC) for perinatal depression and anxiety: a pilot randomized controlled trial by Neda Askari, Renu Gupta, Neesha Hussain-Shamsy, Lucy C. Barker, Trevor Champagne, Raymond W. Lam, Katie Bishop, Jenna Pirmohamed, Maria Michalowska, Vishva Shah, Hailey Katzman, Ashna Jalan, Anushika Shanmuganathan, Vivienne Wang, Simone N. Vigod

“…Measurement-based care (MBC) improves patient outcomes but has not been evaluated for perinatal mental illness. We aimed to assess the feasibility of an MBC protocol in perinatal patients experiencing depression and/or anxiety symptoms. …”
Get full text

Analysis of immune characteristics and inflammatory mechanisms in COPD patients: a multi-layered study combining bulk and single-cell transcriptome analysis and machine learning by Changjin Wei, Yongfeng Zhu, Caiming Chen, Feipeng Li, Li Zheng

“…ObjectiveThis study aims to investigate the potential roles and mechanisms of inflammatory genes in COPD.MethodsTranscriptome data from the airway epithelial tissues of COPD patients and normal individuals were downloaded from the GEO database. …”
Get full text

Patient-reported outcome assessment of adults and adolescents with atopic dermatitis: a cross-sectional qualitative interview study by Parima Ghafoori, Dharm S. Patel, Kimberly Raymond, Elizabeth Brennan, April Mitchell Foster, Kristi Jackson, Helen J. Birch, Wen-Hung Chen

“…Understanding patient experience of relevant symptoms and impacts of AD is crucial for improving outcomes. This study aimed to characterise adult (≥ 18 years) and adolescent (12–17 years) patients’ experiences of AD and assess the content validity of selected patient-reported outcomes (PROs). …”
Get full text

Terahertz dual-band antenna design with improved performances using FSS-based metasurface concept for wireless applications by Youssef Amraoui, Imane Halkhams, Rachid El Alami, Mohammed Ouazzani Jamil, Hassan Qjidaa

“…Furthermore, circuit theory techniques have been used to study FSS structure and electrical equivalent circuits have been created to confirm their functionality. The intended frequency of operation for the FSS is 0.7 THz. …”
Get full text

Assessment of the TGF-β gene and its target miR-1908-5p gene expression and its role in the treatment of beta-thalassemia in Iraqi patients by Manal Lafta Abdulhassn, Hiba Muneer Abdel Hassan Al-Khafaji, Maryam Qasim Mohammed

“…Transforming growth factor-beta (TGF-β) is a cytokine that has multicellular functions. The miRNAs have been confirmed to play important roles in gene expression regulation during the development of a variety of human diseases. …”
Get full text

Identification and validation of oxidative stress-related genes for the diagnosis of sepsis-induced acute lung injury. by Xue Fu, Jiawei Dong, Jian Yang, Xiaotian Zhang, Sen Wang, Shangkun Cai, Yiwei Zhang, Meng Zhang

“…The development and progression of sepsis-induced ALI are accompanied by significant oxidative damage. This study aimed to identify key oxidative stress-related genes associated with sepsis-induced ALI. …”
Get full text

Computational advances in the design and discovery of artemis inhibitors for radiosensitization in cancer therapy by Maryam Bashir, Usman Abdullah, Sadia Nazir, Farhan Siddique, Nasir Jalal

“…The top 16 compounds (ΔG < −8.0 kcal/mol) were further analyzed. Density Functional Theory (DFT) calculations at the B3LYP/6−311+G(d,p) level were used to assess frontier molecular orbitals and reactivity. …”
Get full text

Minimal Clinically Important Difference of Average Daily Steps Measured Through a Consumer Smartwatch in People With Mild-to-Moderate Parkinson Disease: Cross-Sectional Study by Edoardo Bianchini, Marika Alborghetti, Silvia Galli, Clint Hansen, Alessandro Zampogna, Antonio Suppa, Marco Salvetti, Francesco Ernesto Pontieri, Domiziana Rinaldi, Nicolas Vuillerme

“…To define the 3 levels of MCID for avDS, we used an anchor-based method linked to: (1) scales capturing subtle changes in global mobility and motor functions, (2) clinical and health-related measures, and (3) disease-related patient-reported outcomes. …”
Get full text

The efficiency of Amil Zakat Institutions (LAZ) in Indonesian Islamic Banks: Data Envelopment Analysis Approach by Rofiul Wahyudi, Agus Susetyohadi

“…This study aims to analyze the level of efficiency of the LAZ of Islamic bank corporations in Indonesia. …”
Get full text

Development and validation of a nomogram for predicting a forgotten joint in patients one year after robotic-assisted total knee arthroplasty by Chengshuai Zhang, Zhaolun Wang, Jianzeng Zhang, Qi Wang, Dejin Yang, Yixin Zhou

“…Its implementation may enhance patient selection, refine preoperative counseling, and optimize surgical decision-making, potentially improving functional outcomes. Further external validation in broader populations is required to confirm its generalizability. …”
Get full text

Psychometric properties and factor structure analysis of the inventory of statements about self-injury (ISAS) in a Russian non-clinical sample by Andrey A. Kibitov, Sergei S. Potanin, Olga M. Yagina, Vladimir I. Borodin, Margarita A. Morozova

“…Respondents had reported lifetime NSSI and scored above 4 on the ISAS-Functions subscale. Exploratory and confirmatory factor analysis (EFA/CFA) were performed on two randomly formed subgroups to evaluate the factor structure of ISAS. …”
Get full text

MANAGEMENT OF IN-PATIENTS WITH UNCONTROLLED ARTERIAL HYPERTENSION by I. V. Logacheva, V. V. Safronova, N. I. Maximov, S. P. Baranova

“…Aim. To investigate the antihypertensive effectiveness of a fixed perindopril/ amlodipine combination (Prestans) and its effects on the visit-to-visit variability of blood pressure levels and quality of life (QoL) among in-patients with uncontrolled arterial hypertension (AH).Material and methods. …”
Get full text

Multi-relation-pattern knowledge graph embeddings for link prediction in hyperbolic space by Longxin Lin, Huaibin Qin, Quan Qi, Rui Gu, Pengxiang Zuo, Yongqiang Cheng

“…The aim of Knowledge Graph Embedding (KGE) is to acquire low-dimensional representations of entities and relationships for the purpose of predicting new valid triples, thereby enhancing the functionality of intelligent networks that rely on accurate data representation. …”
Get full text

Study on Stress Deformation of Pipe Shed in Shallow Buried Tunnel Considering Micro-Arch Effect by Yao Rong, Wanxu Du, Yang Sun, Fuyang Xiong, Lin Liu, Sufan Yu, Gang Jie

“…This study aims to investigate the influence of the tiny soil arch effect generated by the soil between the steel tubes in the ring direction of the tunnel overrun tube shed on the force deformation of the steel tubes during the working period. …”
Get full text

The Application of Eye Movement Registration Systems in the Assessment of Visuospatial Memory in Preschool Children by Elizaveta A. Panfilova, Margarita S. Aslanova, Sergey V. Leonov, Pavel Yu. Sukhochev, Evgeny A. Sedogin, Irina S. Polikanova

“…Objective. This study is aimed at identifying the relationship between oculomotor patterns in preschool children using the Pupil Invisible eye tracker and their performance on nonverbal visual tasks related to working memory. …”
Get full text