Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial by Alessandra Borgognone, Anna Prats, Anna Prats, Ashish Arunkumar Sharma, Ignacio Martinez-Zalacaín, Ignacio Martinez-Zalacaín, Carles Soriano-Mas, Carles Soriano-Mas, Carles Soriano-Mas, Christian Brander, Christian Brander, Christian Brander, Christian Brander, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, José Moltó, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Rafick-Pierre Sekaly, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno, Jose A. Muñoz-Moreno

“…Furthermore, the three indices and related discriminant features correlated negatively with functional outcomes, such as quality of life and daily functioning, and positively with depression, stress and CNS-related symptoms before RMD administration, while these associations became less discernible at the subsequent timepoints.ConclusionsWhile the direct effect of the intervention on the observed shifts cannot be conclusively determined in this study settings, these findings strengthen the link between gut bacteria, related metabolites, and neurocognitive function in PWH, and provide an analytical framework for future validation studies aimed at discovering predictive biomarkers for neurocognitive impairment in PWH.…”
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Effect of Sustained Clinical Remission on the Risk of Lupus Flares and Impaired Kidney Function in Patients With Lupus Nephritis by Mariele Gatto, Giulia Frontini, Marta Calatroni, Francesco Reggiani, Roberto Depascale, Claudio Cruciani, Silvana Quaglini, Lucia Sacchi, Barbara Trezzi, Grazia Dea Bonelli, Vincenzo L'Imperio, Augusto Vaglio, Claudia Furlan, Margherita Zen, Luca Iaccarino, Renato Alberto Sinico, Andrea Doria, Gabriella Moroni

“…Introduction: This retrospective study on patients with biopsy-proven lupus nephritis (LN) aimed to assess the probability of sustained clinical remission (sCR) and to investigate sCR effects on disease flares and impaired kidney function (IKF). …”
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Genotype–phenotype analysis and functional study of three novel LRP6 variants in non-syndromic oligodontia by Yunyun Yuan, Ya Zhao, Lingqiang Meng, Shuyun Zheng, Hui Li, Jiabao Ren, Beibei Li, Chenyun Dou, Yan Hou, Wenjing Chen, Jing Zhang, Jing Zhang, Yulin Ding, Yulin Ding, Wenjing Shen

“…Recent studies have identified the low-density lipoprotein receptor-related protein 6 (LRP6) gene as an autosomal dominant contributor to TA. Herein we aimed to identify novel LRP6 variants in patients with non-syndromic oligodontia (NSO) and perform functional analyses of these variants.Methods:Whole-exome sequencing (WES) was conducted on probands and their first-degree relatives to identify potential pathogenic variants. …”
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Activity of Different Types of Cactus Forage on Testicular Function and Morphology of Sheep Subjected to Environmental Heat Stress by Giselle Woolley Cardoso da Silva, Fernanda Carolina Ribeiro Dias, Marli do Carmo Cupertino, Alluanan Adelson do Nascimento Silva, Ângela Maria Vieira Batista, Emanuel Felipe de Oliveira Filho, Francisco Fernando Ramos de Carvalho, Ana Lúcia Figueiredo Porto, Valdemiro Amaro da Silva Júnior

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Improving Muscle Function Through a Multimodal Behavioural Intervention for Knee Osteoarthritis and Obesity: The POMELO Trial by Kristine Godziuk, Mary Forhan, Flavio T. Vieira, Joao F. Mota, Jason Werle, John A. Batsis, Lorenzo M. Donini, Mario Siervo, Carla M. Prado

“…ABSTRACT Background Treatments aimed at improving physical function and body composition, including reducing fat mass (FM) and increasing muscle mass, may benefit individuals with advanced knee osteoarthritis (OA) and obesity. …”
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Antioxidant, Physiochemical, and Sensory Properties of Functional Marshmallow Produced from Honey, Strawberry Concentrates, and Hibiscus Extract by Maher M. Al-Dabbas, Etaf G. Abu Samaan, Sehar Iqbal, Hani J. Hamad, Rawan Al-Jaloudi, Mohammad Shahein, Bha’a Aldin Al-Nawasrah, Abdalrahman Al-Zabt, Doa`a Al-Refaie, Nisreen Shehadeh, Mahmoud Abughoush

“…This study, therefore, aimed to develop optimal formulations for functional marshmallow candy using honey, aqueous hibiscus extract, cow’s milk, and strawberry concentrates with partial replacement of table sugar and glucose syrup. …”
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Spatial Information of Somatosensory Stimuli in the Brain: Multivariate Pattern Analysis of Functional Magnetic Resonance Imaging Data by In-Seon Lee, Won-mo Jung, Hi-Joon Park, Younbyoung Chae

“…Fifteen healthy participants completed two functional magnetic resonance imaging (MRI) scans and were stimulated via the insertion of acupuncture needles or by non-invasive touch stimuli (5.46-sized von Frey filament). …”
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The Functional State of the Myocardium in Patients with Ischemic Heart Disease, Diabetes Mellitus Type 2 and Cardiac Insufficiency by Horb Yu., Strona V., Komir I.

“…The aim of the study. To review the scientific literature on the functional status of myocardium in patients with coronary heart disease (CHD), type 2 diabetes, and heart failure. …”
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Association Between Fractional Exhaled Nitric Oxide (FeNO) and Cognitive Function in Patients with Obstructive Sleep Apnea by Zhu Q, Huang L, Zhu L, Zhang X, Ji H, Niu D, Ji W, Ma Q, Chen R, Shi H, Wang Y, Xu L

“…Our study provides early evidence that this simple breath test could help clinicians identify memory issues in OSA patients sooner and more effectively.Keywords: obstructive sleep apnea, polysomnography, fractional exhaled nitric oxide, cognitive function…”
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DYNAMICS OF HIGHGER MENTAL FUNCTION IN PATIENTS WITH OBLITERATING LESIONS OF INTERNAL CAROTID ARTERIES IN SURGICAL BRAIN REVASCUL by R. A. Vinogradov, L. V. Timchenko, A. N. Torgashova, K. A. Bondarovich, T. I. Kаpran, V. V. Seledtsov

“…A number of patients with atherosclerotic lesions of brachiocephalic arteries have reduced cognitive functions. The aim of the study is to compare cognitive functions (CF) in patients who underwent different surgical approaches in the treatment of obliterating atherosclerotic lesion of internal carotid arteries (ICA).MATERIAL AND METHODS. …”
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Tea Catechins: Potential Plant-Derived Feed Additives for Improving Chicken Intestinal Health and Productivity by Bing Tian, Wenjing Zhuang, Yanle Fan, Yun Hu, Xiaoyan Cui, Tingting Li, Liyang Zhang, Xugang Luo, Shengchen Wang

“…The compounds demonstrate dual biological functions: mitigating oxidative tissue damage and actively remodeling gut microbiota composition by suppressing enteric pathogens (e.g., <i>Clostridium</i>) and enriching beneficial bacteria (e.g., <i>Bifidobacterium</i>). …”
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Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions by XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou

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[Translated article] Impact of lower limb lengthening with telescopic nails on functionality and quality of life in patients with achondroplasia by M. Galán-Olleros, J. Alonso-Hernández, C. Miranda-Gorozarri, J. García-Fernández, R.M. Egea-Gámez, Á. Palazón-Quevedo

“…Lower limb lengthening reusing telescopic intramedullary nails (TIMNs) offers an alternative to external fixators, with the potential to enhance functionality, self-esteem, and HRQoL, while reducing complication risks, which this study aims to evaluate. …”
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Cognitive functions in patients suffering from hypertension and hypothyroidism with retrospective evaluation of control over disease compensation. by M. I. Lesiv

“…The aim of the study was to study the status of cognitive functions in hypertensive patients, patients with hypothyroidism, and in patients with combination of these diseases, taking into account the state of disease compensation. 67 patients (36 men and 31 women), average age – 49.84±2.83 years were examined. …”
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Fault Isolation in Network of State Automates by I. V. Bystrova, B. P. Podkopaev

“…Assumed, that functional diagnostics devices for each network component are preliminarily constructed in an optimal way and they consist of a control automata and of a fault discriminator of unit dimension.Aim. …”
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A branching bivariate weibull distribution model for evaluating exosomes in androgen-deprived agency in the presence of prostate cancer by M. Shanmugavalli, K. Majella Jenvi Ignatia, Mary Jiny D, Raman Kumar, Ashok Kumar Bishoyi, S. Renuka Jyothi, Harpreet Kaur Channi, Abhijit Bhowmik, Jasmina Lozanović

“…The study developed a novel model, the branching bivariate Weibull distribution (BBWD), tailored to address CRPC and stems from the maximum likelihood estimation (MLE) function. It considers a medicinal biosystem aimed at transitioning androgen-dependent prostate cancer into an androgen-independent state. …”
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Modeling HTLV-1 and HTLV-2 co-infection dynamics by E. A. Almohaimeed, A. M. Elaiw, A. D. Hobiny

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Extended Hermite–Hadamard inequalities by Lakhlifa Sadek, Ali Algefary

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A Comparative Study on the Joint Coordination of Archery Athletes of Different Skill Levels: Based on Functional Data Analysis by Baifa Zhang, Zhi-Cheng Lin

“…By analyzing the changes between joints through functional data analysis, characteristic parameters can be derived. …”
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Construction optical solitons of generalized nonlinear Schrödinger equation with quintuple power-law nonlinearity using Exp-function, projective Riccati, and new generalized method... by Islam Samir, Hamdy M. Ahmed, Wafaa Rabie, W. Abbas, Ola Mostafa

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