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3861
Structural and functional state of the skin microcirculation in men with different phenotypes of hypertension of low and moderate cardiovascular risk
Published 2024-11-01“…Aim. To study the structural and functional state of skin microcirculation in working-age men with different phenotypes of hypertension (HTN) of low/moderate cardiovascular risk.Material and methods. …”
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3862
The Effectiveness of Acceptance and Commitment-Based Therapy on the Immune Function and Activity Limitations in Patients With Irritable Bowel Syndrome
Published 2021-09-01“…Objective: This study aimed to determine the effectiveness of acceptance and commitment-based therapy on the immune function and activity limitations in patients with irritable bowel syndrome. …”
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3863
Influence of exercise interventions on functional movement screen scores in athletes: a systematic review and meta-analysis
Published 2025-07-01“…Abstract The functional movement screen (FMS) is a widely recognized tool for evaluating movement patterns and identifying potential injury risks in athletes. …”
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3864
Stability and Efficacy of Mucoadhesive Eye Drops Containing Olopatadine HCl: Physicochemical, Functional, and Preclinical In Vivo Assessment
Published 2025-04-01“…<b>Objectives:</b> The aim of this study was to develop novel, viscous eye drops containing olopatadine (OCH) as the active ingredient, polysaccharides hydroxypropyl guar gum (HPG), and sodium hyaluronate (SH), individually, and in combination as functional polymers. …”
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3865
The impact of low-protein diet on residual renal function in dialysis patients: a systematic review and metaanalysis
Published 2025-03-01“…However, the effect of low-protein diets on dialysis patients compared to pre-dialysis patients remains unclear. This study aims to compare residual renal function among dialysis patients following a low-protein diet versus a normal diet, offering valuable insights into the optimal nutritional strategy for preserving residual renal function. …”
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3866
The association between locomotive function and incidence of proximal junctional kyphosis following adult spine deformity surgery
Published 2024-11-01“…Abstract Background and objectives This retrospective review study aimed to determine whether functional mobility test (FMT) results are related to the incidence of proximal junctional kyphosis (PJK) after surgical correction of adult spinal deformity (ASD). …”
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3867
Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity
Published 2025-06-01“…Although animal models using the NMDAR antagonist Dizocilpine (MK-801) replicate cognitive deficits associated with memory and learning disorders, the direct effects of MK-801 on brain network connectivity have not been well characterized.ObjectiveThis study aims to explore the effects of MK-801 on brain network connectivity using functional ultrasound imaging (fUSI) and apply time series analysis methods to mitigate potential statistical confounds in functional connectivity assessments.MethodsfUSI was employed to assess changes in cerebral blood volume (CBV) and network connectivity in MK-801-treated mice. …”
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3868
Short-term BCI intervention enhances functional brain connectivity associated with motor performance in chronic stroke
Published 2025-01-01“…However, the specific mechanisms driving motor function improvements are not fully understood. Objective: We aimed at elucidating the potential functional brain connectivity changes induced by BCI training in participants with chronic stroke. …”
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3869
SIRT3 mediates CPT2 delactylation to enhance mitochondrial function and proliferation in goat granulosa cells
Published 2025-07-01“…Therefore, this study aimed to investigate the regulatory role of SIRT3 in the mitochondrial function and proliferation of goat GCs, as well as the underlying mechanisms involved. …”
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3870
Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function
Published 2025-01-01“…RES treatment restored mitochondrial function in NEFA-stressed BMECs, as evidenced by the increase in MMP, ATP generation and NAD<sup>+</sup>/NADH ratio accompanying the decline in mitochondrial structural abnormalities and cell apoptosis. …”
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3871
A first-in-human application of OPM-MEG for localizing motor activity area: Compared to functional MRI
Published 2024-12-01“…Background: Accurately localizing brain motor areas is vital for protecting motor function during neurosurgical procedures. Magnetoencephalography (MEG) based on optically pumped magnetometer (OPM) improves the availability of MEG in clinical applications. …”
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3872
Validation of noninvasive indices of right ventricular diastolic function. Simultaneous echocardiography and pressure-volume catheterization studies
Published 2025-07-01“…Abstract Background The reliability of the recommended echocardiographic methods for assessing RV diastolic function has been questioned. We aimed to validate noninvasive indices of RV diastolic function, derived from tricuspid Doppler and myocardial deformation metrics, against intrinsic diastolic chamber properties and filling pressures. …”
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3873
Downregulation of AdipoR1 in the hippocampus impairs synaptic function and structure and causes depression-like behavior
Published 2025-08-01“…Adiponectin, an adipokine, crosses the blood‒brain barrier to function in specific brain regions. Previous studies have suggested that the downregulation of adiponectin signaling is involved in the occurrence of depression. …”
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3874
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3875
Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa
Published 2025-06-01“…IntroductionThe diversity of phenotypes, ranging from inherited retinal dystrophies (such as Stargardt disease 1, cone–rod dystrophy 3, and retinitis pigmentosa 19) to late-onset age-related macular degeneration 2, has been attributed to loss-of-function variants in the ABCA4 gene. In this study, we aimed to identify and analyze potential pathogenic ABCA4 variants in patients with Stargardt disease or retinitis pigmentosa and to explore the impact of an intronic variant (NM_000350.3:c.6386 + 4A>G) on mRNA splicing.MethodsWe enrolled three patients from unrelated families with Stargardt disease or retinitis pigmentosa after comprehensive ophthalmological evaluations were performed. …”
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3876
Cognitive Function Deficits Associated With Type 2 Diabetes and Retinopathy: Volumetric Brain MR Imaging Study
Published 2025-03-01“…Studies using histopathology and magnetic resonance imaging have revealed that diabetes‐related chronic hyperglycemia may impact the brain's essential functioning by causing microvascular damage. The aim of this study was to examine the cognitive functioning of type 2 diabetic individuals with and without retinopathy by evaluating their morphological, structural, and biochemical differences. …”
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3877
What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies?
Published 2025-04-01“…Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil. …”
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3878
Effect of DLBS1033 on Functional Outcomes for Patients with Acute Ischemic Stroke: A Randomized Controlled Trial
Published 2021-01-01“…Objective. This study is aimed at measuring the benefit of DLBS1033 in acute ischemic stroke management. …”
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3879
Incremental Prognostic Value of Echocardiography Measures of Right Ventricular Systolic Function in Patients With Chronic Heart Failure
Published 2025-03-01“…Background Tricuspid annular plane systolic excursion (TAPSE), Doppler tissue imaging–derived tricuspid lateral annular systolic wave velocity (S′), and right ventricular fractional area change (RV‐FAC) are the most widely used echocardiographic measures of right ventricular systolic function. This study aimed to compare the prognostic value of TAPSE, S′, and RV‐FAC in a large cohort of patients with chronic heart failure. …”
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3880
Detection and functional assessment of structural variants using whole-genome re-sequencing data in Nellore cattle
Published 2025-08-01“…The identified genes were functionally classified for biological mechanisms and pathways (Gene Ontology - GO) using the panther database. …”
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