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  1. 3861

    Structural and functional state of the skin microcirculation in men with different phenotypes of hypertension of low and moderate cardiovascular risk by A. I. Korolev, V. S. Ososkov, A. A. Fedorovich, M. G. Chashchin, V. A. Dadaeva, A. V. Strelkova, K. V. Omelyanenko, M. A. Mikhailova, A. Y. Gorshkov, O. M. Drapkina

    Published 2024-11-01
    “…Aim. To study the structural and functional state of skin microcirculation in working-age men with different phenotypes of hypertension (HTN) of low/moderate cardiovascular risk.Material and methods. …”
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  2. 3862

    The Effectiveness of Acceptance and Commitment-Based Therapy on the Immune Function and Activity Limitations in Patients With Irritable Bowel Syndrome by Sepideh Shakernejad, Javad Khalatbari, Majid-Mahmoud Alilou

    Published 2021-09-01
    “…Objective: This study aimed to determine the effectiveness of acceptance and commitment-based therapy on the immune function and activity limitations in patients with irritable bowel syndrome. …”
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  3. 3863

    Influence of exercise interventions on functional movement screen scores in athletes: a systematic review and meta-analysis by Ali Asghar Maleki, Seyed Hamed Mousavi, Mohamad Ali Biabangard, Hooman Minoonejad

    Published 2025-07-01
    “…Abstract The functional movement screen (FMS) is a widely recognized tool for evaluating movement patterns and identifying potential injury risks in athletes. …”
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  4. 3864

    Stability and Efficacy of Mucoadhesive Eye Drops Containing Olopatadine HCl: Physicochemical, Functional, and Preclinical In Vivo Assessment by Anđelka Račić, Veljko Krstonošić, Ana Micov, Uroš Pecikoza, Vladimir Dobričić, Erna Turković, Danina Krajišnik

    Published 2025-04-01
    “…<b>Objectives:</b> The aim of this study was to develop novel, viscous eye drops containing olopatadine (OCH) as the active ingredient, polysaccharides hydroxypropyl guar gum (HPG), and sodium hyaluronate (SH), individually, and in combination as functional polymers. …”
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  5. 3865

    The impact of low-protein diet on residual renal function in dialysis patients: a systematic review and metaanalysis by Jingyi Xie, Xiaoqin Liu, Yue Ling, Shuwang Ge, Ying Yao

    Published 2025-03-01
    “…However, the effect of low-protein diets on dialysis patients compared to pre-dialysis patients remains unclear. This study aims to compare residual renal function among dialysis patients following a low-protein diet versus a normal diet, offering valuable insights into the optimal nutritional strategy for preserving residual renal function. …”
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  6. 3866

    The association between locomotive function and incidence of proximal junctional kyphosis following adult spine deformity surgery by Ohsang Kwon, Sanghoon Lee, Haolin Zheng, Dae-Woong Ham, Chungwon Bang, Sang-Min Park, Jin S. Yeom, Ho-Joong Kim

    Published 2024-11-01
    “…Abstract Background and objectives This retrospective review study aimed to determine whether functional mobility test (FMT) results are related to the incidence of proximal junctional kyphosis (PJK) after surgical correction of adult spinal deformity (ASD). …”
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  7. 3867

    Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity by Erik Hakopian, Argishti E. Stepanian, Shan Zhong, Shan Zhong, Kofi A. Agyeman, Kofi A. Agyeman, Nancy Zepeda, Kevin Wu, Charles Liu, Charles Liu, Charles Liu, Charles Liu, Darrin J. Lee, Darrin J. Lee, Darrin J. Lee, Darrin J. Lee, Vassilios Christopoulos, Vassilios Christopoulos, Vassilios Christopoulos, Vassilios Christopoulos

    Published 2025-06-01
    “…Although animal models using the NMDAR antagonist Dizocilpine (MK-801) replicate cognitive deficits associated with memory and learning disorders, the direct effects of MK-801 on brain network connectivity have not been well characterized.ObjectiveThis study aims to explore the effects of MK-801 on brain network connectivity using functional ultrasound imaging (fUSI) and apply time series analysis methods to mitigate potential statistical confounds in functional connectivity assessments.MethodsfUSI was employed to assess changes in cerebral blood volume (CBV) and network connectivity in MK-801-treated mice. …”
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  8. 3868

    Short-term BCI intervention enhances functional brain connectivity associated with motor performance in chronic stroke by Khosrov A. Grigoryan, Karsten Mueller, Matthias Wagner, Diaa Masri, Kerrin J. Pine, Arno Villringer, Bernhard Sehm

    Published 2025-01-01
    “…However, the specific mechanisms driving motor function improvements are not fully understood. Objective: We aimed at elucidating the potential functional brain connectivity changes induced by BCI training in participants with chronic stroke. …”
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  9. 3869

    SIRT3 mediates CPT2 delactylation to enhance mitochondrial function and proliferation in goat granulosa cells by Shuaifei Song, Mingzhi Yang, Jiayue Li, Yaru Li, Lei Wang, Shiyi Yao, Zihan Wang, Qiuyan Li, Yanguo Han, Dejun Xu, Zhongquan Zhao

    Published 2025-07-01
    “…Therefore, this study aimed to investigate the regulatory role of SIRT3 in the mitochondrial function and proliferation of goat GCs, as well as the underlying mechanisms involved. …”
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  10. 3870

    Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function by Longwei Sun, Junpeng Huang, Xiangyang Dou, Zhenyu Dong, Yuan Li, Shujing Tan, Ran Yu, Chengmin Li, Weiguo Zhao

    Published 2025-01-01
    “…RES treatment restored mitochondrial function in NEFA-stressed BMECs, as evidenced by the increase in MMP, ATP generation and NAD<sup>+</sup>/NADH ratio accompanying the decline in mitochondrial structural abnormalities and cell apoptosis. …”
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  11. 3871

    A first-in-human application of OPM-MEG for localizing motor activity area: Compared to functional MRI by Tai Sun, Xiaohan Chi, Yuming Peng, Qianhe Zhang, Kang Liu, Yiwen Ma, Ming Ding, Nan Ji, Yang Zhang

    Published 2024-12-01
    “…Background: Accurately localizing brain motor areas is vital for protecting motor function during neurosurgical procedures. Magnetoencephalography (MEG) based on optically pumped magnetometer (OPM) improves the availability of MEG in clinical applications. …”
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  12. 3872

    Validation of noninvasive indices of right ventricular diastolic function. Simultaneous echocardiography and pressure-volume catheterization studies by Candelas Pérez del Villar, Raquel Prieto-Arévalo, Jorge García-Carreño, Pablo Martínez-Legazpi, Daniel Rodríguez-Pérez, Yolanda Benito, Antonia Delgado-Montero, J. Carlos Antoranz, M. Mar Desco, Cristian Herrera Flores, Rafael Corisco Beltrán, Francisco Fernández-Avilés, Javier Bermejo

    Published 2025-07-01
    “…Abstract Background The reliability of the recommended echocardiographic methods for assessing RV diastolic function has been questioned. We aimed to validate noninvasive indices of RV diastolic function, derived from tricuspid Doppler and myocardial deformation metrics, against intrinsic diastolic chamber properties and filling pressures. …”
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  13. 3873

    Downregulation of AdipoR1 in the hippocampus impairs synaptic function and structure and causes depression-like behavior by Peilin Zhu, Yanmin Luo, Yue Li, Jing Tang, Li Liu, Yuhui Deng, Jing Li, Lin Jiang, Wenyu Yang, Qian Xiao, Shun Wang, Yuning Zhou, Fenglei Chao, Lei Zhang, Chunni Zhou, Yong Tang, Xin Liang

    Published 2025-08-01
    “…Adiponectin, an adipokine, crosses the blood‒brain barrier to function in specific brain regions. Previous studies have suggested that the downregulation of adiponectin signaling is involved in the occurrence of depression. …”
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  14. 3874
  15. 3875

    Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa by Qi Luo, Juan Huang, Lu Shi, Lu Shi, Guanghong Zhang, Linping Xue, Kehu Wu, Xiaoyu Li, Lei Yang, Dujun Li, Liangwei Mao, Jihong Luo

    Published 2025-06-01
    “…IntroductionThe diversity of phenotypes, ranging from inherited retinal dystrophies (such as Stargardt disease 1, cone–rod dystrophy 3, and retinitis pigmentosa 19) to late-onset age-related macular degeneration 2, has been attributed to loss-of-function variants in the ABCA4 gene. In this study, we aimed to identify and analyze potential pathogenic ABCA4 variants in patients with Stargardt disease or retinitis pigmentosa and to explore the impact of an intronic variant (NM_000350.3:c.6386 + 4A&gt;G) on mRNA splicing.MethodsWe enrolled three patients from unrelated families with Stargardt disease or retinitis pigmentosa after comprehensive ophthalmological evaluations were performed. …”
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  16. 3876

    Cognitive Function Deficits Associated With Type 2 Diabetes and Retinopathy: Volumetric Brain MR Imaging Study by Ece Ozdemir Oktem, Dila Sayman, Sevilay Ayyildiz, Çaglar Oktem, Lutfiye Ipek, Behcet Ayyildiz, Fatih Aslan, Emin Utku Altindal, Nilay Yagci, Rumeysa Dikici, Ramazan Karaca, Şeyda Cankaya, Seda Avnioglu, Halil Aziz Velioglu, Burak Yulug

    Published 2025-03-01
    “…Studies using histopathology and magnetic resonance imaging have revealed that diabetes‐related chronic hyperglycemia may impact the brain's essential functioning by causing microvascular damage. The aim of this study was to examine the cognitive functioning of type 2 diabetic individuals with and without retinopathy by evaluating their morphological, structural, and biochemical differences. …”
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  17. 3877

    What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies? by A. Z. P. Brandão, L. M. L. B. F. Lasmar, L. M. A. S. Pertence, M. I. R. Vieira, G. B. Lasmar, V. O. Ganem, E. V. Mancuzo, M. V. N. P. de Queiroz

    Published 2025-04-01
    “…Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil. …”
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    Article
  18. 3878

    Effect of DLBS1033 on Functional Outcomes for Patients with Acute Ischemic Stroke: A Randomized Controlled Trial by Rizaldy Taslim Pinzon, Raymond R. Tjandrawinata, Vincent Ongko Wijaya, Vanessa Veronica

    Published 2021-01-01
    “…Objective. This study is aimed at measuring the benefit of DLBS1033 in acute ischemic stroke management. …”
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  19. 3879

    Incremental Prognostic Value of Echocardiography Measures of Right Ventricular Systolic Function in Patients With Chronic Heart Failure by Francesco Gentile, Michela Chianca, Lorenzo Bazan, Paolo Sciarrone, Vlad Chubuchny, Claudia Taddei, Elisa Poggianti, Claudio Passino, Michele Emdin, Alberto Giannoni

    Published 2025-03-01
    “…Background Tricuspid annular plane systolic excursion (TAPSE), Doppler tissue imaging–derived tricuspid lateral annular systolic wave velocity (S′), and right ventricular fractional area change (RV‐FAC) are the most widely used echocardiographic measures of right ventricular systolic function. This study aimed to compare the prognostic value of TAPSE, S′, and RV‐FAC in a large cohort of patients with chronic heart failure. …”
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  20. 3880