Functional analysis of a new splicing mutation in the <em>MYBPC3</em> gene in hypertrophic cardiomyopathy by R. R. Salakhov, M. V. Golubenko, M. Y. Skoblov, R. R. Savchenko, N. R. Valiakhmetov, E. N. Pavlyukova, M. S. Nazarenko

“…Aim. To study the pathogenic effect in the MYBPC3 splice-site variant in the patient with hypertrophic cardiomyopathy. …”
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Global motion coherent deficits in individuals with autism spectrum disorder and their family members are associated with retinal function by Irene O. Lee, Dennis M. Fritsch, Maximilian Kerz, Jane C. Sowden, Paul A. Constable, David H. Skuse, Dorothy A. Thompson

“…The altered retinal function was associated with the age, intelligence and autism severity of the ASD family members. …”
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Vestibulo-Oculomotor Reflex Dysfunction in Children with Cerebral Palsy Correlates with Gross Motor Function Classification System by Laura Casagrande Conti, Nicola Ferri, Leonardo Manzari, Tommaso Lelli, Maria Mangeruga, Margherita Dal Piaz, Andrea Manzotti, Luca Verrecchia, Marco Tramontano

“…Background/Objectives: This study aims to evaluate the feasibility of the angular vestibulo-ocular reflex (aVOR) function assessment in children with cerebral palsy (CP) using the video Head Impulse Test (vHIT) and to investigate how vestibular impairments correlate with functional motor ability. …”
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Effects of dietary supplementation with Candida krusei on production performance, immune function and ammonia nitrogen emission in broilers by Rui Jia, Hongxia Gu, Jiaju Li, Aijuan Zheng, Zhimin Chen, Chang Wenhuan, Liu Guohua

“…This study aimed to investigate the effects of dietary graded levels of Candida krusei on growth performance, slaughter performance, immune function, nitrogen metabolism and ammonia nitrogen emission of broilers. …”
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Resting-state EEG alterations and cognitive impairment in atrial fibrillation: insights into neural biomarkers and functional connectivity by Min-qiang Bao, Min-qiang Bao, Li Cao, Yi-nong Chen, Guo-liang Gao, Zhi-yong Lu, Jie Wang, Shuang-shuang Chen, Xiao-ning Sheng, Yu Wang

“…Resting-state EEG metrics, including power spectral density (PSD), functional connectivity (FC), cross-frequency coupling (CFC), and sample entropy (EnSA), were analyzed alongside the Montreal Cognitive Assessment (MoCA) scores. …”
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Effect of fat distribution on left ventricular structure and function in different sexes: a Mendelian randomization study by Hang Li, Guangjiao Yin, Guangjiao Yin, Yanfang Zhang, Ziwei Wang, Fang Lv, Rui Li, Juanjuan Qin, Juanjuan Qin, Xujun Ye, Xujun Ye

“…This study aims to reveal the causal relationship between genetic determinants of fat distribution pattern and function of the left ventricular structure in different sexes.MethodsGenetic variants for waist circumference, hip circumference, waist-to-hip ratio (WHR), and body mass index (BMI) were selected from genome-wide association studies conducted in European samples. …”
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Neural progenitor cell transplantation results in structural and functional recovery in a rat model of cerebral palsy by Maryam Tavakoli Lakeh, Seyed Massood Nabavi, Fatemeh Rouhollah, Koorosh Shahpasand, Sahar Kiani

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Selective disruption of gray matter volume covariance in orbitofrontal cortex subregions among patients with functional constipation by Qian Su, Lianzi Liu, Ting Hua, Jian Gong, Hongliang Tian, Jiongyue Yun, Wangli Cai

“…Abstract Functional constipation (FCon) is a prevalent common functional gastrointestinal disorders (FGIDs) frequently linked to mental and psychological disorders. …”
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Latissimus dorsi muscle for functional reconstruction surgery of the triceps surae following soft tissue sarcoma resection by Daniela Kristina Carolino, Keiichi Muramatsu, Yasuhiro Tani, Masaya Ueda

“…We aim to report long-term outcomes of functional latissimus dorsi muscle transfer for triceps surae reconstruction following resection of sarcoma. …”
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The Immunosuppressive Functions of Eosinophils Are Compromised in Patients With Allergic Rhinitis, Particularly Concerning Rab27a Expression by Yun Liao, Minyao Li, Shuo Song, Xuejie Xu, Xiaojun Xiao, Yu Liu, Gui Yang, Pingchang Yang

“…There is still a lack of knowledge about whether eosinophils play a role in immune regulation. The aim of this study is to uncover the immune regulatory functions of eosinophils. …”
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Respiratory long COVID in aged hamsters features impaired lung function post-exercise with bronchiolization and fibrosis by Laura Heydemann, Małgorzata Ciurkiewicz, Theresa Störk, Isabel Zdora, Kirsten Hülskötter, Katharina Manuela Gregor, Lukas Mathias Michaely, Wencke Reineking, Tom Schreiner, Georg Beythien, Asisa Volz, Tamara Tuchel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Sabrina Clever, Timo Henneck, Maren von Köckritz-Blickwede, Dirk Schaudien, Karl Rohn, Klaus Schughart, Robert Geffers, Mika K. Kaneko, Yukinari Kato, Carina Gross, Georgios Amanakis, Andreas Pavlou, Wolfgang Baumgärtner, Federico Armando

“…The underlying pathomechanisms remain unclear, necessitating further research in appropriate animal models. This study aimed to characterize the trajectory of lung regeneration over 112 days in the male hamster model by combining morphological, transcriptomic and functional readouts. …”
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Advances in gut microbiota functions in inflammatory bowel disease: Dysbiosis, management, cytotoxicity assessment, and therapeutic perspectives by Ivan Kushkevych, Michaela Dvořáková, Dani Dordevic, Bożena Futoma-Kołoch, Márió Gajdács, Lamiaa A. Al-Madboly, Mohamed Abd El-Salam

“…By bridging methodological advancements with functional implications, this review aims to enhance our understanding of gut microbiota-host interactions, which are crucial for maintaining health and preventing disease through immune modulation, where microbiota help regulate immune responses and prevent excessive inflammation; nutrient metabolism, including the breakdown of dietary fibers into short-chain fatty acids that support gut health; and colonization resistance, where beneficial microbes outcompete harmful pathogens to maintain microbial balance.…”
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Hindgut microbiota profiling and functional prediction of sheep (Ovis aries) fed with different dietary calcium levels by Muhammad Khan, Xiaoqi Zhao, Xiaojun Ni, Baiji Danzeng, Sikandar Ali, Maida Mushtaq, Hongyuan Yang, Jiachong Liang, Syed Khurram Fareed, Bai Xue, Guobo Quan

“…Abstract Hindgut microbiota plays a crucial role in small ruminant health and productivity, with diet being a key influencing factor. This study aimed to investigate the hindgut microbiota profile and functional prediction in sheep fed with different dietary calcium levels. …”
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Effectiveness of Maitland Mobilisation on Pain and Function in Individuals with Mechanical Low Back Pain: A Systematic Review by Geeta Gill, Vinay Jagga, Sajjan Pal

“…While some studies indicated improvements in ROM, the evidence for its effectiveness compared to other interventions and its long-term impact on pain and function remains unclear. Future well-designed studies are needed to definitively assess the role of Maitland mobilisation in the management of MLBP.…”
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From fragmented to functional: Improving rehabilitation data in Georgia's health information systems for better decision-making by Nino Kotrikadze, Akaki Zoidze, George Gotsadze

“…The UHCP facilities employ the functional assessment tool but no standardized reporting persist. …”
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Comparison of functional outcome in fixed bearing versus mobile bearing implant designs in total knee arthroplasty by Sajjad Ali B, Arun Raja C J, Kathiravan Rajendran

“… Introduction:Total Knee Arthroplasty (TKA) is a common surgical procedure aimed at relieving pain and restoring function in advanced knee arthritis. …”
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Comparison of functional outcome in fixed bearing versus mobile bearing implant designs in total knee arthroplasty by Sajjad Ali B, Arun Raja C J, Kathiravan Rajendran

“… Introduction:Total Knee Arthroplasty (TKA) is a common surgical procedure aimed at relieving pain and restoring function in advanced knee arthritis. …”
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Butylphthalide reduces plaque burden and improves neurological function in carotid atherosclerotic disease: a pooled analysis by Jia Yang, Xinhao Pei, Jianxin Qiang, Lijuan Li, Yanping Liu, Panpan Hao, Panpan Hao

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Inspiration Time: The Ultrasound Variable Necessary to Study the Diaphragm Functionality. A Cross-Sectional Controlled Study by Teresa E Fernández-Pardo PT, MSc, PhD student, Maria Jesús Rodríguez-Nieto PhD, Mercedes Furió-Valverde PT, María García-Arrabé PT, MSc, PhD, Ana Mallo-Lopez PT, MSc, PhD student, Ignacio Mahillo-Fernández PhD, Germán Peces-Barba Romero PhD

“…Conclusion The inspiratory contraction time and the diaphragmatic excursion are two essential variables in the dynamic functional evaluation of the diaphragm, compared to the diaphragmatic thickness measurement that only reports its strength.…”
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Reliability of digitally instructed self-reported 30-second chair stand test for lower extremity function by Leif E. Dahlberg, Oscar Karlsson, Paulina Sirard, L Stefan Lohmander, Ali Kiadaliri

“…Objective: The 30-s Chair Stand Test (30s CST), a valid and reliable test evaluating lower extremity physical function, has been integrated into a digital eHealth program. …”
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