Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein by Maliki Ankavay, Nathalie Da Silva, Angela Pollán, Noémie Oechslin, Katja Dinkelborg, Patrick Behrendt, Darius Moradpour, Jérôme Gouttenoire

“…Background and Aims: Hepatitis E virus (HEV) infection is a leading cause of acute hepatitis worldwide. …”
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Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1 by Xinxin Li, Jinghua Cui, Zanbo Ding, Ziyan Tian, Yiming Kong, Linghai Li, Yang Liu, Wen Zhao, Xueying Chen, Han Guo, Zhengshuo Cui, Xinwei Li, Jing Yuan, Huina Zhang

“…Endothelial dysfunction is an important early event in the pathogenesis of hypertension, yet the impact of K.pn-secreted EVs (K.pn EVs) on endothelial function remains unclear. This study aimed to investigate the effects of K.pn EVs on endothelial function and to elucidate the underlying mechanisms. …”
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Functional echocardiography identifies association between early ventricular dysfunction and outcome in pediatric sepsis by Sonia Reveco, Sonia Reveco, Stella Barbagelata, Stella Barbagelata, Pablo Cruces, Pablo Cruces, Franco Diaz, Franco Diaz, Karla Yohanessen, Marcos Larraín, Mario Guerra, Alexander Bataszew, Alexander Bataszew

“…ObjectiveThis feasibility study aimed to describe the relation between ventricular dysfunction and outcome in pediatric sepsis.MethodsThis prospective observational multicenter study was conducted in two Pediatric Intensive Care Units (PICU). …”
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Association between physical activity and executive function of Chinese adolescents aged 13–18 by Yuan Liu, Xiaojian Yin, Yi Sun, Feng Zhang, Feng Zhang, Cunjian Bi, Yaru Guo, Yaru Guo, Pengwei Sun, Pengwei Sun, Hong Jun, Hong Jun, Yanyan Hu, Yanyan Hu, He Liu, He Liu

“…ObjectiveThis study aimed to investigate the relationship between physical activity (PA) and executive function (EF) among adolescents in China.MethodsUsing a stratified cluster random sampling, we recruited 4,991 adolescents from 11 Chinese cities, including Urumqi, Lhasa, and Naqu etc. …”
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Metagenomic insights into the microbial communities and functional traits of hot springs in Guizhou Province, China by Feng Chen, Min Cheng, Dongyun Rong, Yanyan Wang, Yanyan Wang, Rubing Liang, Muhammad Irfan, Yingqian Kang, Yu Cao, Yu Cao

“…However, recent studies have determined that hot springs not only have a rich microbiota but are also involved in various biogeochemical processes and possess unique characteristics that can be utilized for several biotechnological applications. This study aimed to determine the bacterial taxonomic diversity and functional profiles of 11 hot springs in the Guizhou Province, China.MethodsIllumina high-throughput sequencing was used to sequence the V3–V4 region of the 16S rRNA gene from microorganisms in samples collected from these hot springs. …”
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Impact of preoperative nutritional impairment on physical function early after total hip arthroplasty by Tsutomu Fujita, Satoshi Hamai, Toshimi Konishi, Kazuya Okazawa, Yuki Nasu, Daisuke Hara, Shinya Kawahara, Ryosuke Yamaguchi, Taishi Sato, Ken Utsunomiya, Goro Motomura, Kenichi Kawaguchi, Yasuharu Nakashima

“…Aims: To investigate whether preoperative nutritional status, assessed by the Geriatric Nutritional Risk Index (GNRI), predicts postoperative physical function following total hip arthroplasty (THA). …”
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Narration of a collective traumatic event according to the presence of PTSD and considering the social function by Laura Charretier, Francis Eustache, Mickael Laisney, Jacques Dayan, Jacques Dayan, Florence Fraisse, Vincent de La Sayette, Pierre Gagnepain, Amine Chakli, Carine Klein-Peschanski, Denis Peschanski, Peggy Quinette

“…While the influence of PTSD on narratives has been studied, few studies have measured the effect of social function on the link between PTSD and narrative.ObjectivesThe aim was to measure trauma narratives of the terrorist attacks of November 13, 2015, according to the presence of PTSD and considering the social function (civil or professional) at the time of exposure.MethodsThirty-seven civilians (including 16 women and 21 men) and 22 first responders (including 7 women and 15 men) exposed to the terrorist attacks of November 13, 2015, in France recounted their experiences. …”
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Anterolateral Ligament Reconstruction Combined with Anterior Cruciate Ligament Reconstruction: Clinical and Functional Outcomes by Giuseppe Danilo Cassano, Lorenzo Moretti, Michele Coviello, Ilaria Bortone, Mariapia Musci, Ennio Favilla, Giuseppe Solarino

“…This study aims to assess the clinical and functional outcomes of the ACLR+ALLR combination using biomechanical testing in patients with at least ten months of follow-up. …”
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Macrovascular Function in People with HIV After Recent SARS-CoV-2 Infection by Ana S. Salazar, Louis Vincent, Bertrand Ebner, Nicholas Fonseca Nogueira, Leah Krauss, Madison S. Meyer, Jelani Grant, Natalie Aguilar, Mollie S. Pester, Meela Parker, Alex Gonzalez, Armando Mendez, Adam Carrico, Barry E. Hurwitz, Maria L. Alcaide, Claudia Martinez

“…SARS-CoV-2 infection has been associated with acute CVD complications. The aim of the study was to as-sess macrovascular function as an early indicator of CVD risk in PWH after mild SARS-CoV-2 infection. …”
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Impedance cardiography parameters reflecting left ventricular function are markers of pulmonary arterial hypertension by Yang Wentao, Yang Wentao, Wang Yumiao, Yang Luanluan, Li Xin, Cui Xiaopei

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Impact of diabetes mellitus on myocardial function and clinical outcomes in patients with significant aortic regurgitation by Yuting Tan, Yujie Zhang, Qiuyu Cai, Ruohan Zhao, Weidong Luo, Jingrong Jiang, Jiawei Shi, Tianshu Liu, Li Qiu, Jing Wang

“…However, the additive effects of T2DM on myocardial function and its association with clinical outcomes in patients with aortic regurgitation (AR) is undetermined. …”
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Dynapenia and presarcopenia in patients with coronary atherosclerosis: clinical predictors and cardiac structural and functional features by A. G. Neeshpapa, V. N. Karetnikova, K. E. Krivoshapova, E. I. Karpova, A. N. Kokov, O. L. Barbarash

“…Aim. To assess the prevalence of dynapenia, presarcopenia and their relationship with structural and functional parameters of the heart in patients with coronary atherosclerosis.Material and methods. …”
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Electrosurgical knife with the water‐jet function of tip‐type during endoscopic treatment injection by Satoshi Ono, Yasuko Kurihara, Fumiya Hirose, Hajime Aoki, Kyohei Maejima, Shun Ito, Shun Osumi, Seika Hatori, Kazushi Fukagawa, Shosuke Hosaka, Miho Matsukawa, Ryosuke Kobayashi, Nobuyoshi Yamazaki, Mitsuhiro Fujishiro

“…Abstract Objectives This study aimed to objectively evaluate the water‐jet‐functioned electrosurgical knife injection performances in a desktop experiment. …”
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Effects of vitamin A supplementation on visual function in healthy adults: A systematic review by Kavous Shahsavarinia, Ali Mostafaei, Nooshin Milanchian, Leila Roshangar, Parastu Fallahi, Moloud Balafar, Robab Mehdipour, Fereshteh Farhadi, Hassan Soleimanpour, Nasim Hajipoor, Reza Mohammadi, Hanieh Salehi-Pourmehr

“…Vitamin A plays an important role in various bodily functions, including vision. This systematic review aimed to synthesize the available evidence on the effects of vitamin A supplementation on visual function in healthy adults. …”
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Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus by F. O. Ushanova, T. Y. Demidova, T. N. Korotkova

“…Features of the functional state of the enteropancreatic hormonal system in pregnant women with gestational diabetes mellitus© Fatima O. …”
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Predicting Urinary Function Outcomes Following Low-dose-rate Brachytherapy for Prostate Cancer by Gianni Rüedi, Manolis Pratsinis, Hans-Peter Schmid, Sabine Güsewell, Paul M. Putora, Ludwig Plasswilm, Christoph Schwab, Orlando Burkhardt, Armin Thoeni, Werner Hochreiter, Ladislav Prikler, Stefan Suter, Patrick Stucki, Michael Müntener, Nadja Blick, Hans Schiefer, Gautier Müllhaupt, Daniel S. Engeler

“…Background and objective: Our aim was to develop a tool using readily available clinical parameters to predict the probability of poor urinary function following low-dose-rate brachytherapy (LDR-BT) for localized prostate cancer. …”
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Sex differences and determinants of coronary microvascular function in asymptomatic adults with type 2 diabetes by Jian L. Yeo, Abhishek Dattani, Joanna M. Bilak, Alice L. Wood, Lavanya Athithan, Aparna Deshpande, Anvesha Singh, J.Ranjit Arnold, Emer M. Brady, David Adlam, John D. Biglands, Peter Kellman, Hui Xue, Thomas Yates, Melanie J. Davies, Gaurav S. Gulsin, Gerry P. McCann

“…Men with T2D, but not women, demonstrated worse systolic function and higher extracellular volume fraction than controls. …”
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Bridging the gap: enhancing blood regulatory functions in African contexts through comparative analysis by Washington T. Samukange, Washington T. Samukange, Washington T. Samukange, Verena Kluempers, Chancelar Kafere, Kristina Heinrich, Joanna Atemnkeng, Alireza Khadem Broojerdi, Florence Tirane, Edwin Nkansah, Shani Maboko, Linda Nhukarume, Khamusi Mutoti, Noel Aineplan, Helga Gardasdottir, Helga Gardasdottir, Helga Gardasdottir, Aukje K. Mantel-Teeuwisse, Jens Reinhardt

“…IntroductionIndependent assessments of blood regulatory systems, facilitated by tools such as the WHO's Global Benchmarking Tool (GBT) plus Blood expedites development of National Regulatory Authorites (NRAs) and thus promotes increased access to safe, effective, and quality blood, blood components, and products. The aim of this study was to assess and compare the status of implementation and performance of the regulatory functions for registration and marketing authorization as well as the system for approval of blood, blood components and plasma for fractionation or processes.MethodsWe did this by conducting assisted self-benchmarking in 12 African countries using the GBT plus Blood (registration and marketing authorization function, 34 sub-indicators and approval of blood, blood components, and plasma for fractionation or processes function, 24 sub-indicators). …”
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Liver Function Abnormalities in Patients with Chlamydia psittaci Pneumonia: A Multicenter Retrospective Study by Fang C, Xu L, Lu J, Li Y, Zhao Z

“…Changquan Fang,1,2,* Limin Xu,3,* Jiancong Lu,2 Yujun Li,4,5 Ziwen Zhao1,4,5 1The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Huizhou Central People’s Hospital, Huizhou, Guangdong, People’s Republic of China; 3Department of Geriatrics, Huizhou First Hospital, Huizhou, Guangdong, People’s Republic of China; 4Department of Pulmonary and Critical Care Medicine, Guangzhou First People’s Hospital, South China University of Technology, Guangzhou, Guangdong, People’s Republic of China; 5Department of Pulmonary and Critical Care Medicine, Guangzhou First People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yujun Li; Ziwen Zhao, Department of Pulmonary and Critical Care Medicine, Guangzhou First People’s Hospital, South China University of Technology, No. 1 Panfu Road, Yuexiu District, Guangzhou City, Guangdong Province, People’s Republic of China, Tel +86 13570574008 ; +86 13006872260, Email liyujun_0110@163.com; eyzhaoziwen@scut.edu.cnBackground: Some patients with Chlamydia psittaci pneumonia exhibit liver function abnormalities. In this study, we aimed to elucidate the characteristics of liver function changes and the factors influencing liver injury in patients with Chlamydia psittaci pneumonia, providing a reference for clinical treatment.Methods: The clinical data of patients with Chlamydia psittaci pneumonia admitted to three tertiary Grade A hospitals in Guangdong Province, China, from January 2020 to February 2025 were retrospectively collected. …”
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Gut microbiome and metabolome profiling in coal workers’ pneumoconiosis: potential links to pulmonary function by Xiao Yu, Tao Xiong, Lu Yu, Gaisheng Liu, Fan Yang, Xueqin Li, Yangyang Wei, Xiaojing Wang, Shuting Wei, Yi Jiang, Xiaomei Kong, Shouan Ren, Yiwei Shi

“…Although the impact of gut microbiota on lung diseases is acknowledged, its specific role in CWP is unclear. This study aims to explore changes in the gut microbiome and metabolome in CWP, while also assessing the correlation between gut microbes and alterations in lung function. …”
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