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2461
Histone and non-histone lactylation: molecular mechanisms, biological functions, diseases, and therapeutic targets
Published 2025-06-01“…Histone lactylation has been observed in H2A, H2B, H3, and H4, with H3K18la and H4K12la being the most extensively studied sites, linked to numerous biological functions. Beyond chromatin, Kla has also been identified in a growing number of non-histone proteins, further expanding its functional significance. …”
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2462
Benefits and Limitations of Lean Tools in the Building Design Process: A Functional and Comparative Analysis
Published 2025-05-01“…While Lean Construction has been widely applied in execution phases, its adoption in design remains fragmented, lacking a clear framework for identifying and evaluating Lean tools in this context. This study aims to identify, classify, and evaluate Lean tools applicable to the building design phase, emphasizing their functionalities, benefits, and limitations. …”
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2463
Merging microencapsulated garlic extract as a bioactive ingredient into manufacturing functional soft cheese
Published 2025-04-01“…Abstract The study aimed to produce a functional soft cheese with garlic extract (GE). …”
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2464
A Consumer Perception Study on Functional Dairy Products Among Consumers in Istanbul, Turkey
Published 2019-07-01“…The aim of this study is to understand Turkish consumers’ perception of functional dairy products in three different categories, namely milk, yogurt, and cream cheese, as well as their willingness to buy products with health claims. …”
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2465
Sensory Characteristics of Fermented Dangke Whey Functional Beverage with Different Levels of Honey Addition
Published 2025-04-01“…This study aims to determine the panellist acceptance of the sensory characteristics of fermented whey dangke functional beverages with the addition of different levels of honey. …”
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2466
Microalgae-Based Functional Foods: A Blue-Green Revolution in Sustainable Nutrition and Health
Published 2025-04-01“…This review aims to examine the potential of microalgae as natural ingredients in functional food production, explore the factors limiting their industrial acceptance and utilization, and assess the safety issues associated with human consumption.…”
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2467
Stone-walled terraces restoration: conserving biodiversity and promoting economic functions of farmlands in Lebanon
Published 2022-06-01“…This study showcases the effectiveness of FLR programmes in restoring economic and social functions of terraced Mediterranean farmland while maintaining ecological functionality. …”
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2468
Research on the Correlation between Balance Function and Core Muscles in Patients With Adolescent Idiopathic Scoliosis
Published 2025-03-01“…Objective This study aimed to explore the correlation between balance function and core muscle activation in patients with adolescent idiopathic scoliosis (AIS), compared to healthy individuals. …”
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2469
Atrial Functional Tricuspid Regurgitation: A Comprehensive Review of Pathophysiology, Diagnosis, and Management Strategies
Published 2024-12-01“…Atrial fibrillation (AF), the most prevalent sustained cardiac arrhythmia, is intricately linked with atrial functional tricuspid regurgitation (AFTR), a condition distinguished from ventricular functional tricuspid regurgitation by its unique pathophysiological mechanisms and clinical implications. …”
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2470
Association between thyroid function and osteopenia or osteoporosis: a cross-sectional study in China
Published 2025-05-01“…Abstract Thyroid dysfunction is associated with bone health, but the relationship with osteopenia remains unclear. This study aimed to investigate the association between thyroid function and osteopenia/osteoporosis across different age groups. …”
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2471
Inhibiting immune escape in lung adenocarcinoma: the role of SPARC in suppressing CD276 function
Published 2024-12-01“…Although implicated in the development of several cancers, the functions and mechanisms of SPARC remain unclear. The aim of this study was to investigate whether smooth muscle cell (SMC)-associated SPARC acts an important tumour suppressor in lung adenocarcinoma (LUAD). …”
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2472
Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells
Published 2019-10-01“…Although STAT3 is recognized as an attractive therapeutic target in CRC, conventional approaches aimed at inhibiting its functions have met with several limitations. …”
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2473
Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism
Published 2014-12-01“…Aim of investigation. Complex estimation of endothelial function at non-alcoholic fatty liver disease (NAFLD) in association with early disorders of carbohydrate metabolism, in relation to liver fibrosis severity.Material and methods. …”
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2474
Overlap of Functional Gastrointestinal Disorders: Common Mechanisms of Pathogenesis as a Key to Rational Therapy
Published 2022-12-01“…Aim: to review the common risk factors and links in the pathogenesis of functional gastrointestinal disorders (FGID) to optimize therapy of patients with a combination of multiple FGID.Key points. …”
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2475
A Sphincter-like Function of Pulmonary Vein Ostia in Normal and Atrial Fibrillation Subjects
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2476
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2477
Effects of the Characteristics and Duration of Chronic Pain on Psychosomatic Function in the Community-Dwelling Elderly Population
Published 2020-01-01“…However, only few studies have investigated the impact of catastrophic thinking on chronic pain (CP) in the community-dwelling elderly population. This study aimed to evaluate the characteristics of CP in the community-dwelling elderly population and to investigate the effects of different periods of CP on cognitive and psychological functions. …”
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2478
Neutrophilic Bronchial Inflammation Correlates with Clinical and Functional Findings in Patients with Noncystic Fibrosis Bronchiectasis
Published 2015-01-01“…Neutrophilic bronchial inflammation is a main feature of bronchiectasis, but not much is known about its relationship with other disease features. Aim. To compare airway inflammatory markers with clinical and functional findings in subjects with stable noncystic fibrosis bronchiectasis (NCFB). …”
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2479
Physical Modifications of Kombucha‐Derived Bacterial Nanocellulose: Toward a Functional Bionanocomposite Platform
Published 2024-10-01“…Abstract Sustainable functionalization of bacterial cellulose for cost‐effective bionanocomposites with desired properties has received growing attention in recent years. …”
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2480
Bioactive Metabolites of <i>Dioscorea</i> Species and Their Potential Applications in Functional Food Development
Published 2025-07-01“…Additionally, we discuss the functional food applications and regulations of <i>Dioscorea</i> spp., which possess antioxidant, anti-inflammatory, anti-diabetic, and anticancer properties. …”
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