Identification of antagonistic bacterium Pseudomonas aeruginosa K5 against watermelon fusarium wilt and its role in disease suppression and plant growth promotion by XIU Junqing, YANG Shibing, ZHAO Shengjie, LI Wenyang, Yushanjiang Maimaiti, LI Meng, KANG Baoshan, LIU Liming, GU Qinsheng, WU Huijie

“…Thus, there is an urgent demand to explore other effective strategies. This study aimed to screen out effective antagonistic strains for biocontrol of watermelon wilt disease. …”
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Chronic BPAF exposure differentially enhances fat deposition in mice fed normal or high-fat diets via lipid metabolism dysregulation by Ziquan Lv, Ziquan Lv, Xinyue Xu, Xinyue Xu, Zhi Tang, Yin Liang, Changfeng Peng, Yuxuan Wu, Yuxuan Wu, Dan Sang, Guixuan Jia, Xiaoxiao Hu, Ying Chen, Guangnan Liu, Dan Wang, Suli Huang, Yajie Guo

“…BackgroundBisphenol AF (BPAF), an alternative to Bisphenol A (BPA), is increasingly utilized in various industrial applications, yet its toxicological profile remains incompletely understood. This study aims to investigate the impact of BPAF exposure on obesity and lipid metabolism in male mice subjected to either a normal chow diet (ND) or a high-fat diet (HFD).MethodsMice were exposed to BPAF at a concentration of 100 μg/kg every other day for five months under different dietary conditions, and body weight, rectal temperature, and food intake were monitored regularly. …”
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Lipidomic signatures of ventilator-associated pneumonia in COVID-19 ARDS patients: a new frontier for diagnostic biomarkers by Arthur Kassa-Sombo, Charles Verney, Augustin Pasquet, Julien Vaidie, Deborah Brea, Virginie Vasseur, Adeline Cezard, Antoine Lefevre, Camille David, Eric Piver, Lydie Nadal-Desbarats, Patrick Emond, Hélène Blasco, Mustapha Si-Tahar, Antoine Guillon

“…The lipid signature, composed of 272 lipids, differed between VAP and control patients (p = 0.003). …”
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Thyroid FT4-to-TSH ratio in the first trimester is associated with gestational diabetes mellitus in women carrying male fetus: a prospective bi-center cohort study by Shuoning Song, Yuemei Zhang, Xiaolin Qiao, Yanbei Duo, Jiyu Xu, Jing Zhang, Yan Chen, Xiaorui Nie, Qiujin Sun, Xianchun Yang, Ailing Wang, Zechun Lu, Wei Sun, Yong Fu, Yingyue Dong, Tao Yuan, Weigang Zhao

“…TSH, FT4 and the percentage of positive TPOAb were no significant difference between women with and without GDM, but FT4/TSH ratio was significantly higher in GDM group compared with NGT group [6.97(0.84,10.61) vs. 4.88(0.66,12.44), P=0.025)]. …”
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Harnessing multi-omics and artificial intelligence: revolutionizing prognosis and treatment in hepatocellular carcinoma by Zhen Wang, Zhen Wang, Zhen Wang, Gangchen Zhou, Gangchen Zhou, Rongchuan Cao, Rongchuan Cao, Guolin Zhang, Guolin Zhang, Yongxu Zhang, Yongxu Zhang, Mingyue Xiao, Longbi Liu, Longbi Liu, Xuesong Zhang

“…Furthermore, machine learning models were employed to develop the artificial intelligence-derived risk score (AIDRS) with the aim of predicting patient outcomes and guiding personalized therapy. …”
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Dentate line invasion is a risk factor for locoregional recurrence and distant metastasis following abdominoperineal resection in rectal cancer: a single-centre retrospective cohor... by Zixing Zhu, Dedi Jiang, Yujuan Jiang, Jichuan Quan, Mingguang Zhang, Wei Pei, Jianjun Bi, Qiang Feng, Haitao Zhou, Zheng Wang, Zhaoxu Zheng, Qian Liu, Zhixun Zhao, Jianwei Liang

“…However, the prognostic implications of dentate line invasion (DLI) remain elusive and warrant further investigation. This study aims to evaluate and compare the outcomes of patients with rectal cancer who underwent abdominoperineal resection (APR), distinguishing between those with and without DLI. …”
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R-AI-diographers: a European survey on perceived impact of AI on professional identity, careers, and radiographers’ roles by Nikolaos Stogiannos, Gemma Walsh, Benard Ohene-Botwe, Kevin McHugh, Ben Potts, Winnie Tam, Chris O’Sullivan, Anton Sheahan Quinsten, Christopher Gibson, Rodrigo Garcia Gorga, David Sipos, Elona Dybeli, Moreno Zanardo, Cláudia Sá dos Reis, Nejc Mekis, Carst Buissink, Andrew England, Charlotte Beardmore, Altino Cunha, Amanda Goodall, Janice St John-Matthews, Mark McEntee, Yiannis Kyratsis, Christina Malamateniou

“…Critical relevance statement This paper aims to map out the perceived impact of AI on the professional identity and careers of European radiographers. …”
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Breast tumors from ATM pathogenic variant carriers display a specific genome-wide DNA methylation profile by Nicolas M. Viart, Anne-Laure Renault, Séverine Eon-Marchais, Yue Jiao, Laetitia Fuhrmann, Sophia Murat El Houdigui, Dorothée Le Gal, Eve Cavaciuti, Marie-Gabrielle Dondon, Juana Beauvallet, Virginie Raynal, Dominique Stoppa-Lyonnet, Anne Vincent-Salomon, Nadine Andrieu, Melissa C. Southey, Fabienne Lesueur

“…Moreover, using three different deep learning algorithms (logistic regression, random forest and XGBoost), we identified a set of 27 additional biomarkers predictive of ATM status, which could be used in the future to provide evidence for or against pathogenicity in ATM variant classification strategies. …”
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Risk and impact of stroke across 38 countries and territories of the Americas from 1990 to 2021: a population-based trends analysis from the Global Burden of Disease Study 2021Rese... by Ramón Martinez, Paula Muñoz-Venturelli, Pedro Ordunez, Felipe Fregni, Carlos Abanto, Matias Alet, Tony Fabián Alvarez, Pablo Amaya, Sebastian Ameriso, Antonio Arauz, Miguel A. Barboza, Hernán Bayona, Antonio Bernabé-Ortiz, Juan Calleja, Vanessa Cano-Nigenda, Leonardo Augusto Carbonera, Rodrigo M. Carrillo-Larco, Angel Corredor, Ana Cláudia de Souza, Claudio Jimenez, Fernando Lanas, Sheila Martins, Victor Navia, Nelson Novarro-Escudero, Verónica Olavarría, Bruce Ovbiagele, Kevin Pacheco-Barrios, Octavio Pontes-Neto, Virginia Pujol, Alejandro Rabinstein, Julieta Rosales, Andrés Rosende, Gisele Sampaio Silva, Gustavo Saposnik, Souvik Sen, Fernando D. Testai, Victor Urrutia, Craig S. Anderson, Pablo M. Lavados

“…Summary: Background: Despite substantial declines in burden over time, stroke remains a public health threat in the Americas. This study aimed to assess the current magnitude, trends, and disparities in the estimates of stroke burden by sex and age in the Americas from 1990 to 2021. …”
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The Safety and Efficacy of New DIVA Inactivated Vaccines Against Lumpy Skin Disease in Calves by Gaetano Federico Ronchi, Mariangela Iorio, Anna Serroni, Marco Caporale, Lilia Testa, Cristiano Palucci, Daniela Antonucci, Sara Capista, Sara Traini, Chiara Pinoni, Ivano Di Matteo, Caterina Laguardia, Gisella Armillotta, Francesca Profeta, Fabrizia Valleriani, Elisabetta Di Felice, Giovanni Di Teodoro, Flavio Sacchini, Mirella Luciani, Chiara Di Pancrazio, Michele Podaliri Vulpiani, Emanuela Rossi, Romolo Salini, Daniela Morelli, Nicola Ferri, Maria Teresa Mercante, Mauro Di Ventura

“…There is a need for safer vaccines, especially in LSD-free countries. This research aims to develop and test a safe and efficacious inactivated vaccine. …”
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A novel noninvasive assessment of portal pressure from computational biofluid mechanics in patients with portal hypertension by Lei Zheng, Guangbo Wu, Jiayun Lin, Hongjie Li, Chihao Zhang, Zhifeng Zhao, Min Chen, Zhenghao Wu, Guqing Luo, Qiang Fan, Xiaoliang Qi, Haizhong Huo, Longci Sun, Meng Luo

“…Abstract Background and aims To introduce and assess a novel method for portal pressure measurement based on biofluid mechanics in portal hypertensive patients undergoing surgery. …”
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Grey-to-white matter ratio on computed tomography for predicting neurological outcome in patients with heat stroke: a retrospective cohort study by Hua Wei, Hongling Zhu, Hongling Zhu, Menglong Liu, Menglong Liu, Xiaodan Zhu, Xiaodan Zhu, Anyong Yu, Can Luo, Can Luo, Qingbo Zeng, Qingbo Zeng, Fating Zhou, Fating Zhou, Haizhen Duan

“…ObjectiveGrey-to-white matter ratio (GWR) is an early and sensitive indicator of cerebral oedema in patients with hypoxic-ischaemic brain injury, we aimed to evaluate the prognostic value of GWR for predicting neurological outcome in heat stroke patients.MethodsThis multicentre retrospective analysis included 86 patients with heat stroke patients who underwent cranial computed tomography (CT). …”
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Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches by Wenjie Han, Wenjie Han, Yuhang Zhou, Yuhang Zhou, Yiwen Wang, Yiwen Wang, Xiaolin Liu, Tao Sun, Tao Sun, Junnan Xu, Junnan Xu, Junnan Xu

“…By leveraging metagenomic profiling and machine learning approaches, this study aimed to elucidate gut microbial signatures associated with immune response in lung cancer (LC) and to evaluate the modulatory effects of antibiotic exposure.MethodsA systematic literature search was conducted to identify relevant datasets, resulting in the inclusion of 209 fecal metagenomic samples: 154 baseline samples (45 responders, 37 non-responders, and 72 healthy controls) and 55 longitudinal samples collected during immunotherapy. …”
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Isolation, identification and pathogenicity analysis of Photobacterium damselae subsp. damselae from pearl gentian grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatu ♂ by Xiaopiao ZHONG, Zhengsi CHEN, Yi LI, Huapu CHEN, Yu HUANG, Bei WANG, Jichang JIAN, Jia CAI

“…【Objective】This study aimed to isolate and identify the pathogenic bacteria from diseased pearl gentian grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatu ♂), characterizing the isolate's species, physiological and biochemical properties, drug sensitivity profiles, and pathogenicity, thereby providing a theoretical foundation for disease prevention and control.…”
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HPV genotypes in invasive cervical cancer: prevalence, risk attribution, and optimized vaccine strategies in western China by Yuling Kou, Yuling Kou, Xiao Tang, Xiao Tang, Dongni Liang, Dongni Liang, Chuan Xie, Chuan Xie, Jing Zeng, Jing Zeng, Meng Chen, Meng Chen, Wenjing Fu, Wenjing Fu, Zhonghua Li, Zhonghua Li, Qingfeng He, Tianming Liu, Tianming Liu, Mei Wang, Mei Wang, Wei Wang, Wei Wang, Cheng Wang, Cheng Wang

“…HPV16, 18, 33, 52, and 58 were detected in 1,749 patients (96.6, 95% CI 95.7–97.4), the five most common genotypes in different age groups. HPV genotypes contained in the 9-valent vaccine were detected in 1776 patients (98.1, 95% CI 97.4–98.7). …”
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Pharmacogenomic Study of SARS-CoV-2 Treatments: Identifying Polymorphisms Associated with Treatment Response in COVID-19 Patients by Alexandre Serra-Llovich, Natalia Cullell, Olalla Maroñas, María José Herrero, Raquel Cruz, Berta Almoguera, Carmen Ayuso, Rosario López-Rodríguez, Elena Domínguez-Garrido, Rocio Ortiz-Lopez, María Barreda-Sánchez, Marta Corton, David Dalmau, Esther Calbo, Lucía Boix-Palop, Beatriz Dietl, Anna Sangil, Almudena Gil-Rodriguez, Encarna Guillén-Navarro, Esther Mancebo, Saúl Lira-Albarrán, Pablo Minguez, Estela Paz-Artal, Gladys G. Olivera, Sheila Recarey-Rama, Luis Sendra, Enrique G. Zucchet, Miguel López de Heredia, Carlos Flores, José A. Riancho, Augusto Rojas-Martinez, Pablo Lapunzina, Ángel Carracedo, María J. Arranz, SCOURGE COHORT GROUP

“…However, comprehensive studies correlating clinical outcomes with genetic variants are lacking. The main aim of our study is the identification of host genetic biomarkers that predict the clinical outcome of COVID-19 pharmacological treatments. …”
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Continuous Aspiration Mechanical Thrombectomy for Treatment of Thrombosed Hemodialysis ReliableOutflow Grafts by Osman Ahmed, Mohamad Omar Hadied, Sreekumar Madassery, Merve Ozen, Patrick Tran, Adolfo E. Lizardo, Jordan C. Tasse, Ulku Cenk Turba, Bulent Arslan

“…Aims: To determine the safety and feasibility of continuous aspiration mechanical thrombectomy (CAT) for restoring patency to thrombosed hemodialysis reliable outflow (HeRO) arteriovenous grafts. …”
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Interaction of brain imaging features and effects of intensive blood pressure lowering after endovascular treatment for acute ischaemic stroke: the pre-specified secondary analyses... by Xiaoxi Zhang, Xinwen Ren, Yongxin Zhang, Yongwei Zhang, Lei Zhang, Hongjian Shen, Zifu Li, Pengfei Xing, Ping Zhang, Weilong Hua, Fang Shen, Bing Tian, Wenhuo Chen, Hongxing Han, Liyong Zhang, Chenghua Xu, Tong Li, Yu Gao, Yu Zhou, Qiao Zuo, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Xiaoying Chen, Qiang Li, Lili Song, Craig S. Anderson, Pengfei Yang, Jianmin Liu

“…Methods: ENCHANTED2/MT was a prospective, randomised, open-label, blinded-endpoint, controlled trial that aimed to assess the effectiveness of different intensities of blood pressure control on the functional independence in patients who had received successful endovascular therapy for acute ischaemic stroke from large-vessel occlusion at 44 hospitals in China between July 20, 2020 and March 7, 2022. …”
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Organism profiles and empirical treatments for periprosthetic joint infections by Gongan Jiang, Weijun Wang, Yuhao Yang, Minghao Zhang, Yutao Yang, Qing Jiang

“…Lacking this information is not uncommon, and empirical antibiotic treatment should be adopted as a compromise. This study aimed to develop regional-specific antimicrobial regimens and provide a reference for empirical antibiotic treatment for PJI by retrospectively analyzing the pathogen profiles of PJI patients treated in our center and their antibiotic sensitivities. …”
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Stereoacuity and ocular-associated factors in children aged 3–7 years in Guangxi, Southwest China: a cross-sectional study by Xin Xiao, Xin Xiao, Xin Xiao, Huiyao Huang, Yan Luo, Wuqiang Luo, Lili Li, Enwei Lin, Min Kong, Qi Chen

“…ObjectiveThis study aimed to investigate the distribution of stereoacuity and its ocular-associated factors in children aged 3–7 years in Guangxi, Southwest China.MethodsThis cross-sectional study recruited 4,090 children aged 3–7 years (mean: 5.12 ± 0.95 years) from 12 randomly selected kindergartens via cluster sampling in Nanning City, Guangxi, Southwest China. …”
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