Bioactives and Other Nutritional Components in the Jaggery Production Process by Nisha Pujari, Nirali Dedhia, Sanjay Mahajani, Narendra Shah, Amit Arora

“…All the mineral elements showed a similar affinity towards scum. However, through liquid chromatography–mass spectroscopy, it was seen that most of the polyphenols (75%) that positively influence human health, such as oryzarol, hydrocinnamic acids, gentisic acid, hydrobenzoic acids, etc., were retained in jaggery. …”
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A novel tissue culture method to produce professional antigen-presenting cells from rainbow trout in vitro by Nguyen T. K. Vo, PhD, Lital Sever, PhD, Brian Dixon, PhD, Niels C. Bols, PhD

“…The RT-PCR result showed that the fin-LLCs expressed abundant transcript levels of four markers of pAPCs (Major Histocompatibility (MH) IIα, MH IIβ, S25–7, INXV), three transcript markers of DCs (CD83, CD205, CD209), one transcript marker for macrophages (CSF1R), and one transcript marker for pro-inflammatory responses (IL-1β). Using affinity-purified anti-trout MH IIα and MH IIβ primary antibodies that were generated in house, abundant levels of MH IIα and MH IIβ polypeptides were detected in fin-LLCs by Western blotting. …”
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Exploring the Potential Mechanism of Liupao Tea Using UPLC-Q-TOF/MS and Network Pharmacology by Fang Jia, Qi Yang, Lihao Yao, Yunfei Liu, Jiagang Deng, Jing Leng, Lili Fan, Erwei Hao

“…In rats treated with LPT, 14 prototype compounds and 6 metabolites were detected in serum. Network pharmacology and molecular docking analyses revealed 298 common targets between LPT and GMD, including IL-6, AKT1, and TP53. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…The aim of review. To detect relation between Gilbert's syndrome (GS) and other diseases of a gastrointestinal tract (GIT).Key points. …”
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Optimizing PBMC Cryopreservation and Utilization for ImmunoSpot^® Analysis of Antigen-Specific Memory B Cells by Noémi Becza, Lingling Yao, Paul V. Lehmann, Greg A. Kirchenbaum

“…<b>Background:</b> Measuring frequencies of antigen-specific memory B cells (B_mem), their immunoglobulin (Ig) class and subclass usage, cross-reactivity, and affinity can provide insights into the efficacy of future antibody responses in case of antigen re-encounter. …”
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Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization. by Rajesh P Ringe, Philippe Colin, Gabriel Ozorowski, Joel D Allen, Anila Yasmeen, Gemma E Seabright, Jeong Hyun Lee, Aleksandar Antanasijevic, Kimmo Rantalainen, Thomas Ketas, John P Moore, Andrew B Ward, Max Crispin, P J Klasse

“…NAb PGT145, ligating the Env-trimer apex, left no detectable persistent fraction. The divergence in persistent fractions was further analyzed by depletion of pseudoviral populations of the most PGT151- and PGT145-reactive virions. …”
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Construction of Hcp immunohistochemical library and antibody expression based on single memory B cell sequencing technology by ZHOU Jinrui, WANG Wenhao, GU Yaru

“…The in vitro binding activity of the antibodies was detected by ELISA. Results‍　‍The target protein Hcp with a purity >95% was obtained after expression and purification. …”
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Antigen-specific memory B-cell responses to enterotoxigenic Escherichia coli infection in Bangladeshi adults. by Mohammad Murshid Alam, Amena Aktar, Sadia Afrin, Mohammad Arif Rahman, Sarmin Aktar, Taher Uddin, M Arifur Rahman, Deena Al Mahbuba, Fahima Chowdhury, Ashraful Islam Khan, Taufiqur Rahman Bhuiyan, Yasmin Ara Begum, Edward T Ryan, Stephen B Calderwood, Ann-Mari Svennerholm, Firdausi Qadri

“…Therefore, memory B cell responses and affinity maturation of antibodies to the specific ETEC antigens might be important to understand the mechanism of protection.…”
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A comprehensive in silico investigation unravels the structural and functional consequences of non-synonymous single-nucleotide polymorphisms in human OXTR gene by Puja Mazumder, Shuvo Chandra Das, Sobuj Mondol, Ibrahim Khalil Afif, Mithu Howlader, Shipan Das Gupta, Md. Murad Hossain, Md. Mijanur Rahman

“…Molecular docking studies revealed that three nsSNPs (P95L, P170Q, and R272C) had lower binding affinity with oxytocin which might cause the aberrant function of OXTR. …”
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Exploration of the molecular mechanism of modified Danggui Liuhuang Decoction in treating central precocious puberty and its effects on hypothalamic-pituitary-gonadal axis hormones by Xiaqing Liu, Pinggan Li, Xiangna Yang, Ting Xie, Hua Xu

“…CCK-8, ELISA and qRT-PCR were used to detect the effects of MDGLHD on gonadotropin-releasing hormone (GnRH) secretion and endocrine signaling receptor gene expression. …”
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Mapping Vegetation Dynamics in Wyoming: A Multi-Temporal Analysis using Landsat NDVI and Clustering by N. Kuppala, C. Navneet Krishna, V. V. Sajith Variyar, R. Sivanpillai

“…Gaussian Mixture Models (GMM), Affinity Propagation (AP) and a traditional rule-based classification were used for clustering the pixels in the five NDVI images. …”
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Revisiting Host-Binding Properties of LigA and LigB Recombinant Domains by Henrique M. Pires, Igor R. M. Silva, Aline F. Teixeira, Ana L. T. O. Nascimento

“…The recombinant domain LigA7’-13’ demonstrated affinity for the glycosaminoglycans (GAGs) chondroitin-4-sulfate, chondroitin sulfate, heparin, chondroitin sulfate B, and heparan sulfate, while no binding was detected for LigB1’-7’ with these molecules. …”
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Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian... by Aurora Santin, Aurora Santin, Giulia Pianigiani, Alessandro Gialluisi, Alessandro Gialluisi, Alessandro Pecori, Beatrice Spedicati, Beatrice Spedicati, Simona Costanzo, Mariarosaria Persichillo, Francesca Bracone, Giuseppe Giovanni Nardone, Paola Tesolin, Stefania Lenarduzzi, Anna Morgan, Amalia De Curtis, Wouter van der Valk, Wouter van der Valk, Francis Rousset, Marta Roccio, Marta Roccio, Heiko Locher, Heiko Locher, Licia Iacoviello, Licia Iacoviello, Maria Pina Concas, Giorgia Girotto, Giorgia Girotto

“…SnRNA-seq data analyses revealed a peculiar expression of the ASTN2 gene in the neuronal and dark cells populations, while for SLC1A6 no significant expression was detected. TWAS analyses detected that the ARF4-AS1 gene (eQTL: rs1584327) was statistically significant (p = 4.49 × 10−6) in the hippocampal tissue for the 0.25 kHz trait.ConclusionThis study took advantage of three Italian cohorts, deeply characterized from a genetic and audiological point of view. …”
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From netrin‐1‐targeted SPECT/CT to internal radiotherapy for management of advanced solid tumors by David Kryza, Jennifer Wischhusen, Mathieu Richaud, Maëva Hervieu, Jacqueline Sidi Boumedine, Jean‐Guy Delcros, Sophie Besse, Thomas Baudier, Pierre‐Alexandre Laval, Silvia Breusa, Erwan Boutault, Hugo Clermidy, Nicolas Rama, Benjamin Ducarouge, Mojgan Devouassoux‐Shisheboran, Jean‐Michel Chezal, Anne‐Laure Giraudet, Thomas Walter, Patrick Mehlen, David Sarrut, Benjamin Gibert

“…NP137‐111In provided specific detection of netrin‐1‐positive tumors with an excellent signal‐to‐noise ratio using SPECT/CT imaging in different mouse models. …”
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Effects of exosomes of paratumoral thymus epithelial cells on Treg cell function in patients with thymoma-associated myasthenia gravis by CHEN Liuling, TAN Shuting, BAO Xiaoran, LIU Jingli, LI Jinpin

“…The purity of Tregs detected by flow cytometry was more than 90%, with good purity. …”
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Neural network algorithm for optical-SAR image registration based on a uniform grid of points by V.V. Volkov, E.A. Shvets

“…Such algorithms are used in object detection, change detection, navigation. The paper considers algorithms for optical-to-SAR image registration in conditions of rough image pre-alignment. …”
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Autoradiographic comparison between [11C]PiB and [18F]AZD4694 in human brain tissue by Antonio Aliaga, Joseph Therriault, Kely Quispialaya, Arturo Aliaga, Peter Kunach, Arthur C. Macedo, Robert Hopewell, Nesrine Rahmouni, Jean-Paul Soucy, Gassan Massarweh, Marie-Christine Guiot, Tevy Chan, Jesse Klostranec, Aida Mary Abreu Diaz, Andreia Rocha, Giovanna Carello-Collar, Luiza S. Machado, Marco Antônio De Bastiani, Débora Guerini de Souza, Diogo O. Souza, Aline R. Zimmer, Serge Gauthier, Tharick A. Pascoal, Eduardo R. Zimmer, Pedro Rosa-Neto

“…Displacement studies confirmed high binding affinity of PiB in all tissues, indicating that both amyloid-PET agents compete for the same binding sites. …”
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Polarization toward Tfh2 cell involved in development of MBC and antibody responses against Plasmodium vivax infection. by Pongsakorn Thawornpan, Zulfa Zahra Salsabila, Piyawan Kochayoo, Tipanan Khunsri, Chayapat Malee, Kittikorn Wangriatisak, Chaniya Leepiyasakulchai, Francis Babila Ntumngia, John H Adams, Patchanee Chootong

“…High anti-PvCSP and -PvDBPII seropositivity was detected and most subjects produced MBCs specific to these antigens. …”
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Efficacy of Cheiranthus Cheiri in the Treatment of Pericoronitis: A Double-blind, Randomized, Placebo-controlled Trial with Molecular Docking by Shubhamoy Ghosh, Aritra Roy Chowdhury, Sarbendu Paul, Avipsha Sarkar, Abhijit Rana, Mousumi Koley, Indrani Halder, Suman Chandra, Subhranil Saha

“…Aim: This trial attempted to explore the efficacy of Cheiranthus cheiri (CC) 30 cH against placebos in the treatment of pericoronitis by detecting group differences in pain on the visual analog scale (VAS) over 14 days of intervention. …”
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The role of intracellular and extracellular copper compartmentalization in Alzheimer’s disease pathology and its implications for diagnosis and therapy by Yu-Qi Li, Yu-Qi Li, Shuang-Shuang Tan, Shuang-Shuang Tan, Di Wu, Di Wu, Qian Zhang, Tao Wang, Gang Zheng

“…Furthermore, the use of metal imaging techniques to detect copper in the brain offers a potential diagnostic tool for the early identification of AD.…”
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