Deep Learning Strategies for Detecting and Mitigating Cyber-Attacks Targeting Water-Energy Nexus by Ahmed Abughali, Mohamad Alansari, Ameena S. Al-Sumaiti

Subjects: “…Balanced affinity loss…”
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Computational modeling of superparamagnetic nanoparticle-based (affinity) diagnostics by Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Loïc Van Dieren, Antoine A. Ruzette, Vlad Tereshenko, Haïzam Oubari, Haïzam Oubari, Haïzam Oubari, Yanis Berkane, Yanis Berkane, Jonathan Cornacchini, Jonathan Cornacchini, Filip Thiessen EF, Filip Thiessen EF, Filip Thiessen EF, Filip Thiessen EF, Curtis L. Cetrulo, Curtis L. Cetrulo, Curtis L. Cetrulo, Curtis L. Cetrulo, Korkut Uygun, Korkut Uygun, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch

“…Superparamagnetic IONPs, which exhibit magnetization only in the presence of an external field, can be functionalized with ligands for targeted affinity diagnostics. This study presents a computational model to explore the induced voltage in a search coil when MNPs pass through a simulated blood vessel, aiming to improve non-invasive diagnostic methods for disease detection and monitoring.MethodsA finite element model was constructed using COMSOL Multiphysics to simulate the behavior of IONPs within a dynamic blood vessel environment. …”
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Several Affinity Tags Commonly Used in Chromatographic Purification by Xinyu Zhao, Guoshun Li, Shufang Liang

“…Affinity tags have become powerful tools from basic biological research to structural and functional proteomics. …”
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Combined detection of inhibitors of the activin receptor signaling pathways (IASPs) by means of LC-HRMS/MS for human doping control by Panagiotis Sakellariou, Katja Walpurgis, Andreas Thomas, Alexandre Marchand, Geoff Miller, Frank Dellanna, Mario Thevis

“…Within this research project, a multiplexed detection assay for nine IASPs in doping control serum/plasma samples by means of (immuno-)affinity purification, tryptic digestion and LC-HRMS/MS was developed. …”
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High Affinity Aptamers and Their Specificity for Azaspiracid-2 Using Capture-SELEX by Jiaping Yang, Xinhao Li, Weiqin Sun, Yunyi Cui, Han Chen, Yao Yang, Mingjuan Sun, Lianghua Wang

“…Aptamers offer a cost-effective and convenient approach for the detection of azaspiracids. By employing the Capture-SELEX (Systematic evolution of ligands by exponential enrichment) method to screen aptamers specific to azaspiracid-2, a high-affinity aptamer can be identified for toxin detection. …”
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Studies on Synthetic and Natural Melanin and Its Affinity for Fe(III) Ion by T. G. Costa, R. Younger, C. Poe, P. J. Farmer, B. Szpoganicz

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Redefining proton affinity for heteronuclear molecular species: quantum chemical insights by E. E. Etim, J. P. Shinggu, H. S. Samuel, B. Bako, D. K. Sahoo, L. Mweene, S. Kaya

“…Abstract One of the main problems with experimental methods for detecting proton affinity (PA) is that they cannot perform site-specific protonation. …”
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A self-powered millifluidic device driven by triboelectric generator for the label-free and real-time detection of DNA hybridization by Tara Ghafouri, Sheida Bagherzadeh‑Nobari, Negin Manavizadeh

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A Sensitive, Specific and Fast Electrochemical‐based Nanobiosensor Diagnostic for Xanthomonas albilineans, the Cause of Sugarcane Leaf Scald Disease by Moutoshi Chakraborty, Shamsul Arafin Bhuiyan, Simon Strachan, Muhammad J.A. Shiddiky, Nam‐Trung Nguyen, Narshone Soda, Rebecca Ford

Subjects: “…affinity interaction…”
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Recent Advances in Identifying Biomarkers and High-Affinity Aptamers for Gynecologic Cancers Diagnosis and Therapy by Xiaoqun Ma, Thangavel Lakshmipriya, Subash C. B. Gopinath

“…Aptamer is an artificial antibody selected from the randomized library of molecules and has a high binding affinity to the target biomarker. Targeting cancers in the reproductive organs using aptamers showed an excellent efficiency of detection compared to other probes. …”
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Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress by Chen Zhao, Mengjuan Lin, Yasi Pan, Baoping Yu

“…Cholinergic system involves in the development of visceral hypersensitivity, and high-affinity choline transporter (CHT1) is of crucial importance in choline uptake system. …”
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High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose by Gillian Bonvicini, Sunitha Singh, Lisa Sandersjöö, Tiffany Dallas, Eva Schlein, Amelia D. Dahlén, Sara Lopes van den Broek, Dag Sehlin, Ken G. Andersson, Stina Syvänen

“…Conclusion This study supports the hypothesis that stronger TfR affinity enhances brain uptake at a tracer dose. With the more effective detection of Aβ pathology, stronger TfR affinity is a crucial design feature for future bispecific immunoPET radioligands for intrabrain targets via TfR-mediated transcytosis.…”
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Metastatic Melanomas Express Inhibitory Low Affinity Fc Gamma Receptor and Escape Humoral Immunity by Joel F. G. Cohen-Solal, Lydie Cassard, Emilie M. Fournier, Shannon M. Loncar, Wolf Herman Fridman, Catherine Sautès-Fridman

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Drug susceptibility and genotype affinity of Mycobacterium tuberculosis isolated from surgical specimens of pulmonary tuberculosis patients by K. V. Belousovа, T. V. Umpelevа, N. I. Eremeevа, L. A. Golubevа, T. Yu. Botevа, D. V. Vаkhrushevа

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The high affinity IgE receptor Fc epsilonRI is expressed by human intestinal epithelial cells. by Eva Untersmayr, Giovanna Bises, Philipp Starkl, Charles L Bevins, Otto Scheiner, George Boltz-Nitulescu, Fritz Wrba, Erika Jensen-Jarolim

“…To gain insights in IgE-mediated pathophysiology of the gut, we investigated the expression of the high affinity IgE receptor Fc epsilonRI in human intestinal epithelium.…”
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Affinity Peptide-Based Circularly Permuted Fluorescent Protein Biosensors for Non-Small Cell Lung Cancer Diagnosis by Dengyue Xu, Qingyun Jiang, Zhi Li, Angyang Shang, Jiaqi Liu, Chengyu Xue, Shuai Shao, Hangyu Zhang, Hong Yuan, Bin Wu, Bo Liu

“…Affinity peptides of CEA, SCCAg, and CYFRA 21-1, respectively, were screened by phage display technology, and the peptides’ binding affinities were determined by enzyme-linked immunosorbent assay and biolayer interferometry. …”
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An mRNA-based workflow validating neo-epitope presentation through HLA-I/peptide affinity purification by Arthur Esprit, Dorien Autaers, Kris Thielemans, Elise Pepermans, Elise Pepermans, Kurt Boonen, Kurt Boonen, Geert Baggerman, Lorenzo Franceschini, Karine Breckpot

“…This approach uses mRNA encoding a specific HLA-I-molecule fused to a Twin-Strep-Tag (HLA-TST), allowing affinity-based purification and downstream analysis of pHLA-complexes. …”
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Custom affinity probes reveal DNA-damage-induced, ssDNA-independent chromatin SUMOylation in budding yeast by Vera Tröster, Ronald P. Wong, Arne Börgel, Baris Cakilkaya, Christian Renz, Martin M. Möckel, Karolin Eifler-Olivi, Joana Marinho, Thomas Reinberg, Sven Furler, Jonas V. Schaefer, Andreas Plückthun, Eva Wolf, Helle D. Ulrich

“…Here, we report the isolation and characterization of designed ankyrin repeat protein (DARPin)-based affinity probes directed against budding yeast SUMO (Smt3). …”
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Palladium–iridium nanocubes modified with a high-affinity DNA aptamer as paired viral diagnostic and therapeutic tools by Rudi Liu, Jiuxing Li, Jimmy Gu, Bruno J. Salena, Yingfu Li

“…The trimeric aptamer-based NLAA demonstrated a limit of detection (LOD) of 9.3×103 cp/mL for pseudoviruses expressing the spike protein of SARS-CoV-2, 172- and 12.9-fold lower than that of the monomeric and dimeric aptamer-based NLAAs, respectively. …”
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Quantitative proteomic analysis of residual host cell protein retention across adeno-associated virus affinity chromatography by Thomas M. Leibiger, Lie Min, Kelvin H. Lee

“…To better understand host cell protein (HCP) retention in adeno-associated virus (AAV) downstream processes, sequential window acquisition of all theoretical fragment ion mass spectra (SWATH-MS) was used to quantitatively profile residual HCPs for four AAV serotypes (AAV2, -5, -8, and -9) produced with HEK293 cells and purified using POROS CaptureSelect AAVX affinity chromatography. A broad range of residual HCPs were detected in affinity eluates after purification (Ntotal = 2,746), and HCP profiles showed universally present species (Nuniversal = 1,117) and species unique to one or more AAV serotype. …”
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