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    Advanced microfluidic strategies for core-shell nanoparticles: the next-generation of polymeric and lipid-based drug nanocarriers by Giuseppe Nunziata, Alessandro Borroni, Filippo Rossi

    Published 2025-05-01
    “…This review critically evaluates recent advancements, highlighting the superiority of microfluidic methods over conventional batch techniques, which often suffer from variability and scalability issues. …”
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    Role of hyperthermic intraperitoneal chemotherapy in combination with an intraperitoneal port system in the treatment of patients with advanced ovarian cancer by V. V. Saevets, A. V. Privalov, A. V. Vazhenin, A. Yu. Shamanova, A. A. Mukhin, A. V. Taratonov, Yu.  A. Semenov, T.  N. Shamaeva

    Published 2022-01-01
    “…Features of the chemical composition and method of administration of the drug increase the effectiveness of local exposure to tumor cells. …”
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    Single-cell RNA-sequencing uncovers the dynamic changes of tumour immune microenvironment in advanced lung adenocarcinoma by Lei Cheng, Tianqing Chu, Haijiao Lu, Jialin Qian, Yinchen Shen, Chaoxian Zhao

    Published 2023-07-01
    “…Background The heterogeneity of lung adenocarcinoma (LUAD) plays a vital role in determining the development of cancer and therapeutic sensitivity and significantly hinders the clinical treatment of LUAD.Objective To elucidate the cellular composition and reveal previously uncharacterised tumour microenvironment in LUAD using single-cell RNA-sequencing (scRNA-seq).Methods Two scRNA-seq datasets with 106 829 high-quality cells from 34 patients including 11 normal, 9 early (stage I and II) and 14 advanced (stage III and IV) LUAD were integrated and clustered to explore diagnostic and therapeutic cell populations and their biomarkers for diverse stages of LUAD. …”
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