Universal Fab-Fc masked cytokine prodrug platform: αPD-L1/IL-15 prodrug activates CD44+ CD8+ T cells in tumor-draining lymph nodes to enhance antitumor immunity by Wei Li, Ying Qin, Zejian Wang, Luyao Song, Gen Qi, Wenqiang Shi, Qiongya Zeng, Zilan Song, Ao Zhang, Huili Lu

“…A comprehensive immune correlate analysis was conducted in the tumor and tumor-draining lymph node (TDLN) to identify key effector cells responsible for overcoming resistance, followed by further confirmation with egression of T cell blockade, surgical excision of TDLN, and adoptive transfer experiments. Finally, the synergistic antitumor effects of P-T with other ICB or HPK1 inhibitors were investigated.Results P-T or P-Y using steric hindrance from antibody moiety Fab and Fc shields IL-15 activity in circulation, and reactivates it on cleavage by tumor-specific proteases. …”
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Experimental study on natural circulation cooling system for core catcher with downward-facing heating channel by Seokgyu Jeong, Byeonghee Lee, Jun-young Kang, Seong Ho Hong, Chang Wan Kang, Jin Hyeok Kim

“…Variations in inlet pressure, subcooling, or heat flux had minimal impacts on surface heat transfer characteristics such as boiling curves or heat transfer coefficients. …”
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Macrophagic Ym1 orchestrates γδT cell-derived IL-17 production and keratinocyte functionality to mediate psoriasis-like skin inflammation by Wentao Zhang, Fei Li, Yu Wang, Meiyang Fan, Yan Zhao, Yanglong Guan, Yan Zhou, Shemin Lu, Rikard Holmdahl, Liesu Meng, Wenhua Zhu

“…Natural polymorphism of Ym1 influenced the development of skin inflammation, dependent on macrophages, since adoptive transferring of Ym1-deficient macrophages alleviated disease, whereas recombinant Ym1 worsened it. …”
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Classifying and Coding Design and Construction Information by Nabil Dmaidi

“…These has been the cause of major problems in the transfer of information between these various bodies (1,14). …”
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Genre Identity And Comprehensibility Assessment In The Arabic Versions Of Self-help Manuals by Ilham Ezzarrouki

“…It also applies a model of text comprehensibility assessment to examine knowledge transfer in the manuals. Qualitative and quantitative research methodologies have been adopted to study the causal relationships and the distribution of rhetorical moves, meta-discourse markers and comprehensibility dimensions in the source text and in ten Arabic versions. …”
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“We'll Take your King's Daughter and Everything we Asked for her...”: King Henry V's Struggle for the Throne of the French Kingdom by O. I. Nuzhdin

“…It consisted in the adoption procedure, according to which King Charles VI of France recognized Henry V as his son and heir. …”
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Port Terminal Performance Evaluation and Modeling by Giscard Valonne Mouafo Nebot, Haiyan Wang

“…A particular focus was put on action variables and procedures for container and massified transfer management. The multimodal terminal at Le Havre seaport was adopted as the case study. …”
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Decoupled, wearable soft robotic rehabilitation device for the upper limb by James Greig, Mhairi McInnes, Edward K. Chadwick, Maria Elena Giannaccini

“…This testing of elbow flexion moment transfer supports the effectiveness of the device. …”
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Activities of Arctic Commission under Council of People’s Commissars of USSR in 1928—1930: from Tasks of Scientific Research to Plans for Economic Development by N. I. Burnasheva

“…The most important component of the new stage in the development of the Arctic was the transfer of managerial initiative in organizing work in the north of the country into the hands of the state.…”
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Tomato IPM in Florida by Stephanie Bloem, Russell F. Mizell

“… This document presents a historical narrative of tomato production in Florida that emphasizes the adoption and impact of Integrated Pest Management (IPM) practices and the future challenges facing tomato IPM research and technology transfer. …”
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RESEARCH ON RESPONSE CHARACTERSTIC AND DYNAMIC MODELING OF LAUNCH VEHICLE UNDER THE COLD LAUNCH MODE by ZHOU Di, ZHOU Yuanchun, WANG Huijuan, MA Zhangjian, JIANG Shengpeng

“…To accurately simulate the complicated load transfer pattern of the launch device under cold launch mode, the rigid-flexible coupling dynamic simulation method was adopted to analyze the dynamic response of a launch vehicle, the structural strength was also verified. …”
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Orphan Care in Russia by Victoria Schmidt

“…According to the opinion of the Ministry, the key obstacle to effective de-institutionalization is the lack of professionals in adoption and foster care (Vazhdaeva 2006).…”
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A Method of Trackside Kilometer Post Identification Combined with YOLOv3 Model by QIU Xinhua, WANG Wenkun, JI Yuwen, LI Jia

“…Firstly, a convolutional neural network is used to learn image features and obtain network parameters of each layer. Transfer learning is adopted to obtain possible rectangular region of kilometer post based on the trained network parameters. …”
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Active adaptolates featuring motility-induced percolating structures with an adaptive packing geometry by Aritra K. Mukhopadhyay, Peter Schmelcher, Benno Liebchen

“…This phase, which we term “active adaptolates”, adopts the geometry of the underlying lattice like a frozen phase, forms an interconnected percolated structure, and maintains the ballistic dynamics of the molten phase. …”
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Les conséquences de la réforme aéroportuaire pour les territoires : apports d’une simulation informatique multi-agents by Christopher Jankee, Michel Carrard, Sébastien Verel, Éric Ramat

“…For their part, local authorities, which now manage decentralized airports, must adopt the best strategies to develop and/or sustain their infrastructures. …”
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The role of cooperative membership in promoting agricultural green production technologies among rice farmers in rural China by Chao Chen, Ruohan Peng, Feng Ye, Wenmei Liao

“…Abstract Adopting agricultural green production technologies (AGPTs) is crucial for enhancing agricultural sustainability. …”
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The analysis of un activities in resolving the issue of Kosovo and Metohija by Dimitrijević Duško, Lađevac Ivona, Vučić Mihajlo

“…The Constitutional Framework is regulated as a substantial transfer of state responsibilities by the peoples of Kosovo and Metohija to the provisional institutions of self-government and it should “enjoy substantial autonomy within the Federal Republic of Yugoslavia”. …”
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Assessing veterinary education outcomes in livestock systems: a quasi-experimental study of scientific buffalo husbandry training by Gururaj Makarabbi, Aiswarya Sabu, Navneet Saxena, Madan Lal Sharma

“…The study highlights the importance of targeted, learner-sensitive extension models not only for enhancing knowledge transfer, but also for promoting the adoption of best practices, and for enabling systematic monitoring and evaluation of how the trained subject matter areas are implemented at the field level.…”
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Design and Analysis of Connecting Rod Coupling on Loading Platform by SHAO Jun-peng, CUI Shi-hai, WANG Xi-gui, LI Guang-yi

“…Abstract:According to the requirements of a six degree of freedom load test platform for a wind turbine, a kind of connecting rod coupling is designed One end of the coupling is embedded onto a loading platform which can compensate for the angle and position deviation and transfer torque at the same time Considering that the compensation ability of the diaphragm coupling is small and the additional bearing load will be produced in the process of angle compensation, the coupling adopts the connecting rod to replace the original diaphragm structure. …”
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Geographical indication certification of agricultural products and agricultural carbon emissions—empirical evidence from China by Yu Zhang, Yanping Liu

“…Mechanism analysis demonstrates that GIAP effectively lower agricultural carbon emissions primarily by facilitating farmland transfer, strengthening agricultural socialized services, increasing the proportion of grain crops, and improving technical efficiency. …”
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