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Matrix-Based ACO for Solving Parametric Problems Using Heterogeneous Reconfigurable Computers and SIMD Accelerators
Published 2025-04-01“…With parallel calculations, it is possible to separate the matrix modification of the method into SIMD and multiple-instruction multiple-data (MIMD) components and perform calculations on the appropriate equipment. …”
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Balloon and Glue Technique: A Modification of Distal Reinforcement to Prevent Anastomotic New Entry, Reducing Replacement Range in Acute Type A Aortic Dissection
Published 2025-03-01“…One persistent challenge is the prevention of distal anastomotic new entry tears, which frequently necessitate additional intervention. Modification of the distal reinforcement technique offers a straightforward solution by combining existing hemostatic agents with tools such as occlusion balloons. …”
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Additive interaction of conjoint tobacco smoking and heavy drinking on hypertension prevalence in rural Uganda: a community-based cross-sectional study
Published 2025-01-01“…To determine effect modification due to combined tobacco smoking and heavy drinking, the relative excess risk due to interaction (RERI) was computed. …”
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Novel Quinoline- and Naphthalene-Incorporated Hydrazineylidene–Propenamide Analogues as Antidiabetic Agents: Design, Synthesis, and Computational Studies
Published 2024-12-01“…Additionally, <b>7g</b> had strong binding with aldose reductase (−9.20 kcal/mol) in comparison to quercetin (−9.95 kcal/mol). …”
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Integrated Computational Approach to Rational Drug Design Targeting SIK2/3: From Theory to Practice
Published 2024-11-01“…Subsequently, employing iterative chemical modifications guided by human expertise, we further optimized these leads, enhancing their efficacy and specificity. …”
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Multiscale computational evaluation of Vitex trifolia phytochemicals as VEGFR2 inhibitors for targeted breast cancer therapy.
Published 2025-01-01“…However, optimizing the ADMET profile through structural modifications and nanocarrier delivery, along with in vivo and in vitro experimental validation, will enhance its therapeutic potential.…”
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A new incision for unilateral cleft lip repair developed using animated simulation of repair on computer
Published 2007-01-01“…The computer can be utilized as a useful tool in the analysis and planning of surgery and new methods can be developed and attempted subsequently with greater confidence.Aim:We decided to see if an improved lip repair could be developed with the use of computers. …”
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A new incision for unilateral cleft lip repair developed using animated simulation of repair on computer
Published 2007-01-01“…The computer can be utilized as a useful tool in the analysis and planning of surgery and new methods can be developed and attempted subsequently with greater confidence. …”
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A clinical trial evaluating feasibility and acceptability of a brain-computer interface for telerehabilitation in patients with stroke
Published 2025-04-01“…This innovative system merges brain-computer interface (BCI) and functional electrical stimulation (FES) technologies to rehabilitate upper limb function following a stroke. …”
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3-O Sulfated Heparan Sulfate (G2) Peptide Ligand Impairs the Infectivity of <i>Chlamydia muridarum</i>
Published 2025-07-01“…The observed neutralization effect of G2 peptide on <i>C. muridarum</i> entry suggests the possibility of sulfated-like domains being present on the EBs. In addition, data generated from our in silico computational structural modeling indicated that the G2 peptide ligand had significant affinity towards the <i>C. muridarum</i> lipid bilayer. …”
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Computerised analysis of non-conjugate spiral bevel gear mesh using an advanced and fast-converging tooth contact model
Published 2025-07-01“…This additional manipulation complicates the process of determining the contact trace and increases the computational load. …”
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Investigating the Impact of Structural Features on F1 Car Diffuser Performance Using Computational Fluid Dynamics (CFD)
Published 2025-04-01“…This study utilizes Computational Fluid Dynamics (CFD) to optimize the aerodynamic performance of a Formula 1 (F1) car diffuser, investigating the effects of vane placements, end-flap positions, and other structural modifications. …”
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Computational Investigation of the Hemodynamic Effects of the Location of a Re-Entry Tear in Uncomplicated Type B Aortic Dissection
Published 2024-10-01“…This study aimed to examine the hemodynamic modifications in uncomplicated type B aortic dissection in relation to the location of re-entry tears using a computational fluid dynamics simulation. …”
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Computational design and cheminformatics profiling of omeprazole derivatives for enhanced proton pump inhibition of potassium-transporting ATPase alpha chain 1.
Published 2025-01-01“…Our research investigates the strategic modification of omeprazole (OMP) derivatives to improve their binding affinity to targeted proteins, thereby enhancing their chemical reactivity, stability, and toxicity profiles. …”
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Computational investigation of natural compounds as inhibitors against macrolide-resistant protein using virtual screening, molecular docking and MD simulations
Published 2025-05-01“…The results indicate that these compounds could potentially serve as inhibitors of macrolide resistance. However, while computational validations were part of this research, additional in-vitro studies are necessary to develop these potential inhibitors into therapeutic drugs.…”
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