Hepatocyte nuclear factor 4-α is necessary for high fat diet-induced pancreatic β-cell mass expansion and metabolic compensations by Francieli Caroline de Ramos, Robson Barth, Marcos Rizzon Santos, Milena dos Santos Almeida, Sandra Mara Ferreira, Alex Rafacho, Antônio Carlos Boschero, Gustavo Jorge dos Santos, Gustavo Jorge dos Santos

“…AimsThis study investigates the role of Hepatocyte Nuclear Factor 4α (HNF4α) in the adaptation of pancreatic β-cells to an HFD-induced obesogenic environment, focusing on β cell mass expansion and metabolic adaptations.Main methodsWe utilized an HNF4α knockout (KO) mouse model, with CRE-recombinase enzyme activation confirmed through tamoxifen administration. …”
Get full text

Unlocking the potential of flavonoid biosynthesis through integrated metabolic engineering by Yuan Wang, Jiahong Chen, Genhe He, Li Yin, Yonghui Liao

Get full text

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…Secondary outcomes included patient self-reported measures of BMI and eating psychopathology, visual analogue scale measuring motivation and ability to recover; psychosocial functioning (assessed using the Work and Social Adjustment Scale). …”
Get full text

Comprehensive characterization of poplar HSP20 gene family: genome-wide identification, stress-induced expression profiling, and protein interaction verifications by Lincui Shi, Yude Kang, Ling Ding, Liejia Xu, Xiaojiao Liu, Anmin Yu, Aizhong Liu, Ping Li

“…Results To elucidate the distribution, structural features, and functional characteristics of HSP20 proteins in P. yunnanensis, a combination of bioinformatics tools and experimental validation was utilized. …”
Get full text

Impact of Tetracycline Stress on Water Quality and Rhizosphere Microbial Communities of <i>Eichhornia crassipes</i>: Implications for Bioremediation by Dandan Sun, Huan Zhang, Guojun Pan, Zhenhua Zhang, Jincheng Xing, Jiangye Li, Yan Gao, Wei Chen, Xin Lu

Get full text

PROSPECTS OF IMPLEMENTING STEEL FRAMES IN MULTIFAMILY RESIDENTIAL CONSTRUCTION by Maksym Anatoliiovych Kostiuchenko, Oleksandra Volodymyrivna Shevchenko

“…This method emphasizes a steel frame core with a dynamic facade that adapts to changing functional and aesthetic needs while maximizing recyclability. …”
Get full text

Gut Microbiota Response to Experimental Acute Cold Stress in Juvenile Yellowfin Tuna (<i>Thunnus albacares</i>) by Junhua Huang, Zhengyi Fu, Wei Yu, Bowen Hou, Jinhui Wu, Tao Zhang, Zhenhua Ma

Get full text

Genome-wide identification of the TGF-β superfamily and their expression in the Chinese mitten crab Eriocheir sinensis by Yu Su, Siyu Mou, Yifan Song, Huanglong Zhang, Qian Zhang

Get full text

The Construction Path and Protection Measures of Wetland Park from the Perspective of National Participation in the New Era by Liping Li, Lifen Li

“…In addition, it should have elastic adaptability, complex benefits, and special regional characteristics, to create an elastic dynamic system that can adapt to changes in planning and design, improve social public service functions, set up public access points, stimulate media benefits, and integrate regional characteristics.…”
Get full text

COMPONENT FOR REMOTE DATA AVAILABILITY BASED ON THE ESP32 MICROCONTROLLER, A WIRELESS INTERFACE AND THE HTTP PROTOCOL by David Alejandro Chentes Ramos, Thaily Blanco Baro, Fidel Ernesto Hernández Montero

“…The developed system underwent extensive testing, including verification of remote management of sensed data, user account administration, and adaptation to different screen types. The tests confirmed that the system meets the requirements for functionality, accessibility, and adaptability. …”
Get full text

Accessibility for people with motor disabilities at CEOs in Brazil: an ecological study by Djalma Antonio de LIMA JÚNIOR, Magda Lyce Rodrigues CAMPOS, Elisa Miranda COSTA, Rejane Christine de Sousa QUEIROZ, Ana Margarida Melo NUNES, Nilcema FIGUEIREDO, Paulo Sávio Angeira de GOES, Erika Barbara Abreu Fonseca THOMAZ

“…The structural items analyzed included corridors and doors adapted for wheelchairs, functional wheelchairs, access ramps with handrails, and bathrooms adapted for PwMD. …”
Get full text

Necessary reporting of reaction yield for method evaluation: Considering Knoevenagel synthesis of ferulic acid by Hanah T. Rheay, David L. Compton, Korey J. Brownstein, Christopher D. Skory

Get full text

Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

Get full text

Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
Get full text

Ultrastructure of the Sensilla on Antennae and Mouthparts of Larval and Adult <i>Cylas formicarius</i> (Coleoptera: Brentidae) by Yuanchang Xu, Pengbo He, Faxu Lu, Mengjiao Li, Shahzad Munir, Mingfu Zhao, Yixin Wu, Yueqiu He, Guowen Tang

Get full text

Oxidative desulfurization of petroleum products using decorated cobalt oxide on the surface of modified carbon nanotubes-ICHEC-1887 by A. Kazemi-Beydokhti, H. Hassanpour souderjani

“…The results show that the combination of metal oxide and functionalized nanoparticles presents better efficiency in sulfur removal. …”
Get full text

Decision-Making Modeling in Agro-Food Systems Using Type-2 Interval-Valued Linguistic Complex Neutrosophic Sets by R. K. Saini, Florentin Smarandache, Moh. Kasim, Ashik Ahirwar

“…They have three separate membership functions: truth (T), falsity (F), and indeterminacy. …”
Get full text

PSYCHOACOUSTICALLY MOTIVATED TIME-FREQUENCY DICTIONARY BUILDING FOR UNIVERSAL SCALABLE AUDIOCODER BASED ON THE SPARSE APPROXIMATION by V. Y. Herasimovich, Al. A. Petrovsky

“…The article studies the process of creating a perceptually-motivated dictionary of the timefrequency functions based on the wavelet packet transform optimized for the input signal frame and its utilization in the universal scalable real-time audiocoder. …”
Get full text

A Constrained Multi-Objective Optimization Algorithm with a Population State Discrimination Model by Shaoyu Zhao, Heming Jia, Yongchao Li, Qian Shi

“…A simple yet effective resource allocation model is incorporated to address the potential computational resource waste associated with dual populations, enhancing the resource utilization. Comprehensive tests, including comparisons with seven state-of-the-art algorithms, were conducted on 47 benchmark functions and 12 real-world problems. …”
Get full text

Host Plant Dependence of the Symbiotic Microbiome of the Gall-Inducing Wasp <i>Trichagalma acutissimae</i> by Yingnan Wang, Yuanchen Zhang, Ran Li, Yujian Li, Muha Cha, Xianfeng Yi

“…These findings suggest that the symbiotic microbiome of <i>T. acutissimae</i> larvae is influenced by host plant species, yet different microbial compositions may perform similar functions, implying the potential role of symbiotic microbiota in the adaptation to high-tannin oak leaves. …”
Get full text