Nutrient conditions affect antimicrobial pharmacodynamics in Pseudomonas aeruginosa by Maik Kok, Thomas Hankemeier, J. G. Coen van Hasselt

“…We show that single-nutrient modifications minimally affected bacterial growth rate. …”
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<i>Lactobacillus rhamnosus GG</i> as Biosensor for Oral and Systemic Health Conditions: A Pilot Study by Pooja Mali Rai, Andrei Cristian Ionescu, Alessio Soggiu, Antonella Panio, Sourav Panda, Paolo Savadori, Gianluca Martino Tartaglia, Massimo Del Fabbro, Funda Goker

“…Each subject’s salivary composition also presented its unique, characteristic proteomic signature. …”
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Production of subtilisin proteases in bacteria and yeast by A. S. Rozanov, S. V. Shekhovtsov, N. V. Bogacheva, E. G. Pershina, A. V. Ryapolova, D. S. Bytyak, S. E. Peltek

“…Meanwhile, there is an effort to adapt the expression of these enzymes to other microbes, in particular species of the yeast Pichia pastoris.…”
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Using machine learning to unravel chemical and meteorological effects on ground-level ozone: Insights for ozone-climate control strategies by Zhiyuan Li, Yifan Wang, Junling Liu, Junrui Xian

“…The machine learning-based modelling framework developed in this study can be easily adapted to new sampling sites with minor modifications if necessary.…”
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Phenotypic and transcriptomic analyses reveal major differences between apple and pear scab nonhost resistance by Vergne, Emilie, Chevreau, Elisabeth, Ravon, Elisa, Gaillard, Sylvain, Pelletier, Sandra, Bahut, Muriel, Perchepied, Laure

“…Pre-invasive defense, such as stomatal closure, could be inferred, as well as several post-invasive defense mechanisms (apoplastic reactive oxygen species accumulation, phytoalexin production and alterations of the epidermis composition). In addition, a comparative analysis between pear scab host and nonhost interactions indicated that, although specificities were observed, two major defense lines seems to be shared in these resistances: cell wall and cuticle potential modifications and phenylpropanoid pathway induction. …”
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Characterization of protein glycosylation in an Asgard archaeon by Satoshi Nakagawa, Hiroyuki Imachi, Shigeru Shimamura, Saeko Yanaka, Hirokazu Yagi, Maho Yagi-Utsumi, Hiroyuki Sakai, Shingo Kato, Moriya Ohkuma, Koichi Kato, Ken Takai

“…Unexpectedly, three structurally different N-glycans lacking the conventional core structure were identified in this archaeon, presenting unique compositions that included atypical sugars. Notably, one of these sugars was likely HexNAc modified with a threonine residue, similar to modifications previously observed in mesophilic methanogens within the Methanobacteriati. …”
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Acidic pH Modulates Cell Wall and Melanization in <i>Paracoccidioides brasiliensis</i>, Affecting Macrophage Interaction by Rafael de Souza Silva, Wilson Dias Segura, Rogéria Cristina Zauli, Reinaldo Souza Oliveira, Vitor Vidal, Eduardo Correa Louvandini, Patricia Xander, Suzan Pantaroto Vasconcellos, Wagner Luiz Batista

“…In this study, we demonstrate that acidic pH induces melanization in <i>P. brasiliensis</i>, modulates its cell wall composition, and alters the interaction with macrophages. …”
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CPFD Simulation of Operation Characteristics of a 10t/d Sludge and Biomass Co-incineration Fluidized Bed Reactor by REN Shaohui, YU Qiao, LIN Li, XIANG Jiatao, MA Lun, ZHANG Shihong

“…Reactor geometry adjustments induced &lt;2% compositional changes, but opposing feed inlets revolutionized mixing dynamics: fuel dispersion uniformity eliminated localized rich zones, intensifying turbulence to boost CO₂ yield by 24% (15.74% vs. 12.66%), enhance CNO→NO conversion (NO↑14%; CNO↓32%), and homogenize temperatures—though a persistent flow dead zone in the upper-right corner induced a 1,217 K hotspot.ConclusionsThis study establishes definitive operational guidelines for sludge-biomass co-incineration FBRs: 1) Maintain primary air &gt;805 Nm³/h to ensure turbulent fluidization while limiting secondary air to ≤30% total flow to balance burnout enhancement against CNO accumulation; 2) Restrict biomass particle size ≤3 cm (equivalent spherical diameter) and prioritize rice husk over wood for high-S/N sludge blends to minimize CNO/H₂S emissions; 3) Employ dolomite bed material (150-275μm) at 500 mm initial height and 800-850℃ for moderate SO₂ control while avoiding particle sizes &gt;225μm that degrade fluidization; 4) Implement opposing feed inlets as a low-cost retrofit to intensify turbulence, elevating NO output by 14% and reducing CNO by 32%—though complementary design modifications (e.g., baffle installation, outlet repositioning) are recommended to eliminate identified thermal hotspots. …”
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Explaining the Pattern of Effective Factors in Building the Capacity of Extension Experts in the Development of Smart Climate Agriculture in the Northwestern Provinces of the Count... by M. Rafiee Sefid Dashti, S.M. Mirdamadi, S.J. Farajollah Hosseini, S. Shokri

“…To determine the reliability of the questionnaire, Cronbach's alpha and composite reliability coefficients were used, and for this purpose, 25 questionnaires were completed by a group identical to the research group. …”
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Group composition It would be interesting to explore the benefit of more homogeneous groups’ composition rather than the artefactually heterogeneous groups that were evaluated in THRIVE. …”
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Expanding the frontiers of additive manufacturing: Higher microstructure identification through probability modeling by Muhammad Shoaib, Muhammad Idrees, Hakeem Ullah, Aasim Ullah Jan, Touqeer Ahmad, Ali Akgül, Magda Abd El-Rahman, Seham M. Al-Mekhlafi

“…In this probabilistic framework, it became possible to express modifications in the properties of metal, polymer, ceramic, and composite microstructures. …”
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THE MODIFIED MARINE PREDATOR ALGORITHM FOR SOLVING OPTIMIZATION PROBLEMS (MMPA) by Nisreen Al Barrak, Hegazy Zaher, Naglaa Ragaa Saeid, Eman Oun

“…It is integrated into the transaction phase of the algorithm to guide search agents toward optimal solutions adaptively. The Modified Marine Predators Algorithm was evaluated on 23 benchmark functions, encompassing unimodal, multimodal, and composite landscapes, to assess its efficiency and robustness. …”
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Functional hydrogel empowering 3D printing titanium alloys by Weimin Zhang, Jiaxin Zhang, He Liu, Yang Liu, Xiao Sheng, Sixing Zhou, Tiansen Pei, Chen Li, Jincheng Wang

“…However, the primary drawbacks of traditional titanium alloy prosthesis are their much higher elastic modulus than cancellous bone and poor interfacial adhesion, which lead to poor osseointegration. 3D-printed porous titanium alloys can partly address these issues, but their bio-inertness still requires modifications to adapt to different physiological and pathological microenvironments. …”
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Differential diagnosis algorithm of endogenous catatonia, catatonia-morphic and catatonia-mimicking states by D. N. Safonov

“…The aim is to develop pathomorphosis adapted clinical algorithm of endogenous catatonia differential diagnostics. …”
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