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321
Research on detection methods of related substances and degradation products of the antitumor drug selpercatinib
Published 2025-01-01“…BackgroundSelpercatinib, a selective RET kinase inhibitor, is approved for treating various cancers with RET gene mutations such as RET-rearranged thyroid cancer and non-small cell lung cancer. …”
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322
Tailored SrFeO3-δ for chemical looping dry reforming of methane
Published 2025-03-01“…Co-doping of the B-site of Sr0.98FeO3-δ increases oxygen mobility and CH4/CO2 activation, resulting in high activity in the CL-DRM process. …”
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323
Targeted doping induces interfacial orientation for constructing surface-functionalized Schottky junctions to coordinate redox reactions in water electrolysis
Published 2024-10-01“…Impressively, the designed B–C3N4@Fe3C||S–C3N4@Fe3C pair requires only a low voltage of 1.52 V to achieve efficient water electrolysis at 10 mA cm−2. This work highlights the potential of functionalized Schottky junction catalysts for coordinating redox reactions in water electrolysis, thereby resolving the trade-off between catalytic activity and stability.…”
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324
Liposomal and Nanostructured Lipid Nanoformulations of a Pentacyclic Triterpenoid Birch Bark Extract: Structural Characterization and In Vitro Effects on Melanoma B16-F10 and Walke...
Published 2024-12-01“…<b>Conclusions:</b> The standardized TTs, including betulin, lupeol, and betulinic acid, showed good stability and superior activity compared to pure betulinic acid. …”
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325
Research on the Characteristics of Electrolytes in Integrated Carbon Capture and Utilization Systems: The Key to Promoting the Development of Green and Low-Carbon Technologies
Published 2025-06-01“…Recent breakthroughs reveal that ternary IL hybrid electrolytes can achieve nearly 100% CO Faradaic efficiency (FE) through microenvironment modulation, while L-histidine additives boost CH<sub>4</sub> selectivity by 23% via interface modification. …”
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326
AI-enabled alkaline-resistant evolution of protein to apply in mass production
Published 2025-02-01“…Through two rounds of design, we ensured that the selected mutant has enhanced functionality, including higher thermal stability, extreme pH resistance, and stronger affinity, thereby validating the generalized capability of the LLM in meeting specific demands. …”
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327
One-step synthesis of epoxy/cyclic carbonate bifunctional polycarbonates with functional groups
Published 2025-06-01“…This work not only demonstrates a highly efficient and selective catalytic system but also provides a strategy for expanding the application potential of CO2-based polycarbonates in advanced materials.…”
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328
Carbon supported dual functional materials for integrated carbon dioxide capture and methanation: Performance of different support materials and carbon footprint assessment
Published 2025-09-01“…It is found that Co modified CaONi DFMs supported by plastic derived MWCNTs displayed excellent performance with approximately 0.15 mmol/gDFMs of CH4 yield and even 100 % of CH4 selectivity in ICCM. This may be contributed by the enhanced CO2 adsorption/activation and H2 chemisorption with Co addition. …”
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329
Identification of Bacterial Oligopeptidase B Inhibitors from Microbial Natural Products: Molecular Insights, Docking Studies, MD Simulations, and ADMET Predictions
Published 2025-05-01“…MD simulations confirmed the stability of their interactions with OPB active sites, maintaining favorable binding conformations throughout the simulation period. …”
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330
Optimized extraction and kinetic study of cholesterol oxidase from a newly isolated Escherichia fergusonii strain from local whey samples: insights through a combined experimental...
Published 2025-01-01“…The enzyme retained almost 72.0% of its initial activity after 80 days of storage at 4 °C. Furthermore, the ChoX enzyme revealed acceptable stability at a pH value of 6.5 to 8.5, maintaining its initial activity of more than 50.0%. …”
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331
Development of a candidate mRNA vaccine based on Multi-Peptide targeting VP4 of rotavirus A: an immunoinformatics and molecular dynamics approach
Published 2025-07-01“…Simulation of immune responses revealed potent B-cell and T-cell activities, macrophage responses, and significant cytokine synthesis. …”
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332
Copper(I) Complexes with Terphenyl-Substituted NPN Ligands Bearing Pyridyl Groups: Synthesis, Characterization, and Catalytic Studies in the S-Arylation of Thiols
Published 2025-07-01“…The NPN ligands adopt a κ<sup>3</sup>-coordination mode, stabilizing the copper centers in distorted tetrahedral geometries. …”
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333
Transformation of CO2 to C2+ alcohols by tailoring the oxygen bonding via Fe-based tandem catalyst
Published 2025-08-01Get full text
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334
Dielectric barrier discharge plasma catalysis for CO2 conversion: Recent progress and perspectives
Published 2025-09-01“…These interdependent effects collectively determine their activity, selectivity, and stability. Additional emphasis is placed on plasma-assisted catalyst synthesis techniques and innovative approaches to mitigate carbon deposition, offering insights into the development of more efficient and durable catalytic systems for CO2 conversion. …”
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335
Recent advances and challenges in solid sorbents for CO2 capture
Published 2025-06-01“…This review offers an extensive assessment of recent progress in solid sorbent technology, outlining the enhancement of material characteristics, functionalization methods, and synthesis processes that improve CO₂ capture efficiency. Furthermore, the document highlights the significance of thermodynamic stability, sorbent selectivity, and impurity tolerance to enhance adsorption efficiency in various operating conditions. …”
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336
Characterization of phage HZY2308 against Acinetobacter baumannii and identification of phage-resistant bacteria
Published 2024-11-01“…Interestingly, the phage-resistant strain, AB48-R was screened through natural selection. Compared to the wild strain AB48, the adsorption efficiency of the phage to AB48-R diminished. …”
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337
Unlocking Methane Generation via Photo‐Thermal‐Coupled CO2 Hydrogenation by Integrating FeNiCrMnCo Multicomponent Alloy with GaN Nanowires
Published 2025-07-01“…The turnover number approaches 20,160 mole CH4 per mole of MCA over a continuous operation period of 120 h, showcasing remarkable stability. Mechanistic investigations reveal that the unique MCA provides a flexible platform for tailoring the electronic and catalytic properties to optimize the adsorption and activation of CO₂ and H₂, thus leading to efficient and selective CO₂ methanation. …”
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338
Shaping viral immunotherapy towards cancer-targeted immunological cell death
Published 2025-07-01“…BackgroundOncolytic viruses (OVs) have the ability to efficiently enter, replicate within, and destroy cancer cells. …”
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339
Design and Validation of a Simplified Method to Determine Minimum Bactericidal Concentration in Nontuberculous Mycobacteria
Published 2025-04-01“…MBC values provide useful additional information regarding MIC values since the MBC/MIC ratio reveals whether antibiotics have bactericidal or bacteriostatic activity according to the species, which is pivotal for selecting the most adequate antibiotic combination to ensure efficient treatment management.…”
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340
Effects of conversion of Chinese fir forest to broad-leaved forests on phosphorus components and transformation in rhizosphere and non-rhizosphere soils
Published 2024-08-01“…Chinese fir(Cunninghamia lanceolata)is mainly distributed in subtropical areas of China, and its soil acidification and phosphorus utilization efficiency are low. It is of great significance to study the effects of Chinese fir plantation transformation on soil P for the stability of ecosystem and sustainable forest management. …”
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