Modeling functional connectivity changes during an auditory language task using line graph neural networks by Stein Acker, Jinqing Liang, Ninet Sinaii, Kristen Wingert, Atsuko Kurosu, Sunder Rajan, Sara Inati, William H. Theodore, Nadia Biassou, Nadia Biassou

“…Functional connectivity (FC) refers to the activation correlation between different brain regions. …”
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Outcomes of Multidisciplinary Low-Vision Rehabilitation Using Two Questionnaires and the International Classification of Functioning, Disability, and Health by Suksri Chotikavanich, Akarawit Eiamsamarng, Thanaporn Layangool, Wichuda Krutthong, Siriwan Loket, Rungtip Yingyong, Somthin Dongngam, Waree Nujoi, Jaruwan Jai-ai, Nattapon Sarinak, Ekpipat Eksupapan, Saranya Sagan, Peeraya Chaowalitwong

“…The ICF scores also showed significant improvement in most domains, including seeing functions, mobility across different locations, transportation use, meal preparation, economic self-sufficiency, community life, and recreational activities (P < 0.01). …”
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Identification of functional near-infrared spectroscopy for older adults with mild cognitive impairment: a systematic review by Bo Yang, Xia Deng, Xianfeng Qu, Yingjie Li, Lei Guo, Nengwei Yu

“…This systematic review aimed to investigate the functional near-infrared spectroscopy (fNIRS) features of older adults with MCI compared with those with normal cognitive function to assist in the diagnosis of MCI.MethodsA literature search was conducted in electronic databases, including PubMed, Web of Science, Embase, and Cochrane Library, up to June 15, 2024. …”
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Effects of dietary fiber on Chinese children with functional constipation and targeted modification of gut microbiota and related metabolites by Pei Xiao, Ting Song, Xiao Lu Li, Yong Mei Xiao, Rui Xue Wang, Fei Fei Song, Dan Li, Ai Hua Zhang, Ying Wang, Ting Zhang, Ting Zhang

“…BackgroundAlthough dietary fiber is widely recommended for preventing and treating functional constipation (FC), clinical trial evidence remains limited and the efficacy has not been sufficiently tested in children.PurposeThis study aimed to evaluate the effects of dietary fiber on FC symptoms, while identifying modulations in gut microbiota and associated metabolic changes.ResultsBetween January 1, 2024, and June 1, 2024, a total of 60 patients diagnosed with FC were enrolled in the study across three centers; however, 54 children completed the study. …”
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Gene‐Smoking Interaction in Insulin Sensitivity and β‐Cell Function Among Normal Glucose Tolerance Individuals by Pan Gu, Shuai Zheng, Sijie Zhang, Jie Yuan, Hao Hong, Jinglan Dai, Jingyi Zhao, Kuanfeng Xu, Tao Yang, Qi Fu, Sipeng Shen, Hao Dai

“…ABSTRACT Objective To identify genetic loci that exhibit potential interactions with smoking status on insulin sensitivity and islet β‐cell function within normal glucose tolerance (NGT) populations. …”
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Father’s adolescent body silhouette is associated with offspring asthma, lung function and BMI through DNA methylation by Negusse Tadesse Kitaba, Toril Mørkve Østergaard, Marianne Lønnebotn, Simone Accordini, Francisco Gómez Real, Andrei Malinovschi, Anna Oudin, Bryndis Benediktsdottir, Francisco Javier Callejas González, Leopoldo Palacios Gómez, Mathias Holm, Nils Oskar Jõgi, Shyamali C. Dharmage, Svein Magne Skulstad, Vivi Schlünssen, Cecilie Svanes, John W. Holloway

“…Change in FBS across sexual maturation associated with DNAm at loci including NOP10, TRRAP, EFHD1, MRPL17 and NORD59A;ATP5B and showed strong correlation in reduced gene expression in loci NAP1L5, ATP5B, ZNF695, ZNF600, VTRNA2-1, SOAT2 and AGPAT2. …”
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Research on Stability of Removal Function in Figuring Process of Mandrel of X-Ray-Focusing Mirror with Variable Curvature by Jiadai Xue, Yuhao Li, Mingyang Gao, Dongyun Gu, Yanlin Wu, Yanwen Liu, Yuxin Fan, Peng Zheng, Wentao Chen, Zhigao Chen, Zheng Qiao, Yuan Jin, Fei Ding, Yangong Wu, Bo Wang

“…By introducing time-varying removal functions for material removal, the model establishes a variable-curvature factor function, which correlates actual downward pressure with parameters such as contact radius and contact angle, thus linking the variable-curvature surface with a planar reference. …”
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Using an Electronic Goniometer to Assess the Influence of Single-Application Kinesiology Taping on Unstable Shoulder Proprioception and Function by Ewa Bręborowicz, Izabela Olczak, Przemysław Lubiatowski, Piotr Ogrodowicz, Marta Ślęzak, Maciej Bręborowicz, Leszek Romanowski

“…While KT application did not significantly influence shoulder proprioception, it did improve patients’ perceived joint stability and function.…”
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Functional characterization of SIZ1 homologs reveals reduced TSWV susceptibility of mutant Nicotiana benthamiana lines by Jelli Venkatesh, Seo-Young Lee, Ghimire Sunita, Jin-Kyung Kwon, Joung-Ho Lee, Byoung-Cheorl Kang

“…Despite considerable research efforts, the specific function of SIZ1 in plants remains largely unknown. …”
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Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. by Wenbo Tang, Matthew Kowgier, Daan W Loth, María Soler Artigas, Bonnie R Joubert, Emily Hodge, Sina A Gharib, Albert V Smith, Ingo Ruczinski, Vilmundur Gudnason, Rasika A Mathias, Tamara B Harris, Nadia N Hansel, Lenore J Launer, Kathleen C Barnes, Joyanna G Hansen, Eva Albrecht, Melinda C Aldrich, Michael Allerhand, R Graham Barr, Guy G Brusselle, David J Couper, Ivan Curjuric, Gail Davies, Ian J Deary, Josée Dupuis, Tove Fall, Millennia Foy, Nora Franceschini, Wei Gao, Sven Gläser, Xiangjun Gu, Dana B Hancock, Joachim Heinrich, Albert Hofman, Medea Imboden, Erik Ingelsson, Alan James, Stefan Karrasch, Beate Koch, Stephen B Kritchevsky, Ashish Kumar, Lies Lahousse, Guo Li, Lars Lind, Cecilia Lindgren, Yongmei Liu, Kurt Lohman, Thomas Lumley, Wendy L McArdle, Bernd Meibohm, Andrew P Morris, Alanna C Morrison, Bill Musk, Kari E North, Lyle J Palmer, Nicole M Probst-Hensch, Bruce M Psaty, Fernando Rivadeneira, Jerome I Rotter, Holger Schulz, Lewis J Smith, Akshay Sood, John M Starr, David P Strachan, Alexander Teumer, André G Uitterlinden, Henry Völzke, Arend Voorman, Louise V Wain, Martin T Wells, Jemma B Wilk, O Dale Williams, Susan R Heckbert, Bruno H Stricker, Stephanie J London, Myriam Fornage, Martin D Tobin, George T O'Connor, Ian P Hall, Patricia A Cassano

“…<h4>Background</h4>Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.…”
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Biomechanical effects of postural and cognitive loads on trunk of workers performing assembly tasks at hand functional height by Huishuan WU, Yu JIN, Yan LIU, Siyi ZENG, Cunwen QIAN, Kezhi JIN

“…In manual tasks, combinations of hand functional height (defined as working height below the waist), awkward postures, and cognitive load are common risk factors. …”
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Parkinson's disease-related pattern (PDRP) identified using resting-state functional MRI: Validation study by Andrea Rommal, An Vo, Katharina A. Schindlbeck, Andrea Greuel, Marina C. Ruppert, Carsten Eggers, David Eidelberg

“…Recently, we developed a fully non-invasive approach to identify analogous disease networks with resting-state functional MRI (rs-fMRI) using independent component analysis (ICA) and bootstrap resampling. …”
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HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1 by Chengcheng Li, Sen Ren, Chengqi Yan, Cheng Wang, Tao Jiang, Yu Kang, Jing Chen, Hewei Xiong, Jiahe Guo, Guoyong Jiang, Shuoyuan Liu, Pengjuan Nie, Zhenbing Chen

“…TFs exhibiting significant variations across age groups were identified and subsequently validated. …”
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Seasonal Variations in the Structure and Function of the Gut Flora in Adult Male Rhesus Macaques Reared in Outdoor Colonies by Longbao Lv, Feiyan Zhang, Haimei Zhou, Wenxian Xiao, Yingzhou Hu, Wenchao Wang, Zhu Zhu, Fangming Zhu, Dongdong Qin, Xintian Hu

“…Compared with other seasons, carbohydrate metabolic function was significantly upregulated in winter (<i>p</i> < 0.01), amino acid metabolic function was relatively increased in spring, and energy metabolic function and the metabolic function of cofactors and vitamins were significantly downregulated in winter and relatively upregulated in summer. …”
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Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity by Erik Hakopian, Argishti E. Stepanian, Shan Zhong, Shan Zhong, Kofi A. Agyeman, Kofi A. Agyeman, Nancy Zepeda, Kevin Wu, Charles Liu, Charles Liu, Charles Liu, Charles Liu, Darrin J. Lee, Darrin J. Lee, Darrin J. Lee, Darrin J. Lee, Vassilios Christopoulos, Vassilios Christopoulos, Vassilios Christopoulos, Vassilios Christopoulos

“…To account for the nonstationarity and autocorrelation inherent in fUSI time series, an AutoRegressive Integrated Moving Average (ARIMA) model was applied to stabilize the mean and remove autocorrelation, ensuring more reliable signal analysis.ResultsOur analysis revealed that MK-801 significantly disrupts functional connectivity (FC) across key brain regions, including the hippocampus, mPFC, and striatum. …”
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Recruitment of renal functional reserve by intravenous amino acid loading in a sheep model of cardiopulmonary bypass by Taku Furukawa, Alemayehu H. Jufar, Clive N. May, Roger G. Evans, Andrew D. Cochrane, Bruno Marino, Peter R. McCall, Sally G. Hood, Ian E. Birchall, Jaishankar Raman, Pei Chen Connie Ow, Anton Trask-Marino, Lachlan F. Miles, Rinaldo Bellomo, Yugeesh R. Lankadeva

“…Abstract Background Cardiopulmonary bypass (CPB) may decrease the renal functional reserve (RFR). However, the temporal changes in RFR after during the recovery period after CPB remains unknown. …”
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Bacterial community composition and function in different habitats in Antarctic Fildes region revealed by high-throughput sequencing by Yi-He Zhang, Yi-He Zhang, Yong-Qiang Hu, Yin-Xin Zeng, Yin-Xin Zeng, Yin-Xin Zeng, Yin-Xin Zeng, Yin-Xin Zeng, Ting Hu, Wei Han, Yu Du, Zhong Hu, Shan-Shan Meng

“…The influence of penguin feces on soil bacterial community composition and ecological function was observed in this study. The study findings will improve our understanding of bacterial community composition and function in various habitats in maritime Antarctica under the background of global climate change.…”
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Functional work disability from the perspectives of persons with systemic lupus erythematosus: a qualitative thematic analysis by Behdin Nowrouzi-Kia, Aaron S. Howe, Anson Li, Jeremy Tan, Natalia Saade-Cleves, Kevon Jules, Malak Sadek, Ali Bani-Fatemi, Antonio Avina-Zubieta, Mary T. Fox, William Shaw, Derek Haaland, Janet Pope, Paul R. Fortin, Kathleen S. Bingham, Christine Peschken, Jennifer Reynolds, Catherine Ivory, Dafna D. Gladman, Murray B. Urowitz, Jorge Sanchez-Guerrero, Lily S. H. Lim, Stephanie Keeling, Patti Katz, Mahta Kavkan, Dennisse Bonilla, Wils Nielsen, Zahi Touma

“…Methods With the objective of creating an SLE-related functional profile rooted in work disability (WD) prevention, 46 SLE patients were purposively recruited from Canadian medical centres. …”
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Spatial Information of Somatosensory Stimuli in the Brain: Multivariate Pattern Analysis of Functional Magnetic Resonance Imaging Data by In-Seon Lee, Won-mo Jung, Hi-Joon Park, Younbyoung Chae

“…We hypothesized that performance of brain-based prediction models may vary across the types of stimuli, and neural patterns of voxels in the SI and parietal cortex would significantly contribute to the prediction of stimulated locations. …”
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Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters by Ricardo da Silva Antunes, Vicente Fajardo-Rosas, Esther Dawen Yu, Rosa Isela Gálvez, Adam Abawi, E. Alexandar Escarrega, Amparo Martínez-Pérez, Emil Johansson, Benjamin Goodwin, April Frazier, Jennifer M. Dan, Shane Crotty, Grégory Seumois, Daniela Weiskopf, Pandurangan Vijayanand, Alessandro Sette

“…We observe distinct dynamics in spike-specific responses across multiple vaccine doses. While antibody levels increase and stabilize with each booster, T cell responses quickly plateau and remain stable. …”
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