Classification of Cell Therapy Products by Cell Manipulation Degree and Functions Performed: Analysis of International Regulatory Approaches by M. A. Vodyakova, N. S. Pokrovsky, I. S. Semenova, V. A. Merkulov, E. V. Melnikova

“…A common principle adopted by regulatory agencies in the US, EU, EAEU, and Russia is to classify manipulation as minimal if the manipulated cells preserve their biological characteristics and physiological function. A defining characteristic of the homologous use of cells or tissues is their administration to perform their inherent functions in the body. …”
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Metagenomic and physicochemical profiling reveal microbial functions in pit mud for Jiang-Nong Jianxiang Baijiu fermentation by Lianbin Cao, Hongmei Sun, Ziyi Xu, Xiaoxiao Xu, Guangchuan Shi, Jianqiang Zhang, Changli Liang, Tongbiao Li, Chaoying Liu, Mingcheng Wang, Shilin Tian, Enzhong Li

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The Impact of Frailty Indices on Predicting Complications and Functional Recovery in Proximal Humerus Fractures: A Comparative Study by Ekrem Özdemir, Oya Olcay Özdeş, Fatih Emre Topsakal, Nasuhi Altay, Esra Demirel

“…Outcomes included complications, reoperations, rehospitalizations, and functional results measured by the American Shoulder and Elbow Surgeons (ASES) score. …”
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Effect of fat distribution on left ventricular structure and function in different sexes: a Mendelian randomization study by Hang Li, Guangjiao Yin, Guangjiao Yin, Yanfang Zhang, Ziwei Wang, Fang Lv, Rui Li, Juanjuan Qin, Juanjuan Qin, Xujun Ye, Xujun Ye

“…This study provides evidence for a causal relationship between fat distribution and LV structure and function across both sexes.…”
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Functional redundancy of the posterior hippocampi is selectively disrupted in non-demented older adults with β-amyloid deposition by Jenna K. Blujus, Michael W. Cole, Elena K. Festa, Stephen L. Buka, Stephen P. Salloway, William C. Heindel, Hwamee Oh

“…Further, our findings indicate that functional redundancy may underscore a network metric different from global functional connectivity of the LFC.…”
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Temporal Dynamics of Functional Connectivity in Temporal and Extra-Temporal Lobe Epilepsy: A Magnetoencephalography-Based Study by Suhas M.V, N. Mariyappa, Karunakar Kotegar, Ravindranadh Chowdary M, Raghavendra K, Ajay Asranna, Viswanathan L.G, Sanjib Sinha, Anitha H

“…<italic>Methods:</italic> Temporal metrics such as Change Between States, Entropy of Transition Patterns, Entropy of Transition Probabilities, Dwell Time, Stability, and Max L1 Distance derived from dynamic functional connectivity matrices were analyzed across eight frequency bands (delta, theta, alpha, beta, low gamma, mid gamma, high gamma and broadband) in TLE and ETLE patients. …”
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Advances in gut microbiota functions in inflammatory bowel disease: Dysbiosis, management, cytotoxicity assessment, and therapeutic perspectives by Ivan Kushkevych, Michaela Dvořáková, Dani Dordevic, Bożena Futoma-Kołoch, Márió Gajdács, Lamiaa A. Al-Madboly, Mohamed Abd El-Salam

“…These bacteria contribute significantly to gut microbial functions, yet their cytotoxic and viability characteristics under disease conditions remain poorly understood. …”
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Comprehensive analysis of the functional and immunological significance of ETV4 in pan-cancer and its validation in digestive tumors by Lingli Huang, Lingli Huang, Lingli Huang, Lingli Huang, Xujia Li, Xujia Li, Xujia Li, Xujia Li, Silan Huang, Silan Huang, Silan Huang, Silan Huang, Qi Jiang, Qi Jiang, Qi Jiang, Qi Jiang, Chang Jiang, Chang Jiang, Chang Jiang, Chang Jiang, Wenzhuo He, Wenzhuo He, Wenzhuo He, Wenzhuo He, Yuchen Cai, Yuchen Cai, Yuchen Cai, Yuchen Cai, Guifang Guo, Guifang Guo, Guifang Guo, Guifang Guo

“…Cytoscape, GSCALite, CancerSEA, STRING, HPA, TIGER, TISIDB, and R were used to assess ETV4’s expression and functional impact on basis of the TCGA and GTEx databases. …”
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Functional Analysis of the Cyclin E Gene in the Reproductive Development of Rainbow Trout (<i>Oncorhynchus mykiss</i>) by Enhui Liu, Haixia Song, Wei Gu, Gaochao Wang, Peng Fan, Kaibo Ge, Yunchao Sun, Datian Li, Gefeng Xu, Tianqing Huang

“…As a commercially valuable aquaculture species, rainbow trout (<i>Oncorhynchus mykiss</i>) urgently require solutions to growth inhibition associated with reproductive development. To elucidate the function of the cell cycle regulator Cyclin E genes (<i>CCNE1</i> and <i>CCNE2</i>) in this process, we cloned the genes and analyzed their relative expression across various tissues and gonadal developmental stages. …”
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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning by Eugenia Mazzaferro, Endrina Mujica, Hanqing Zhang, Anastasia Emmanouilidou, Anne Jenseit, Bade Evcimen, Christoph Metzendorf, Olga Dethlefsen, Ruth JF Loos, Sara Gry Vienberg, Anders Larsson, Amin Allalou, Marcel den Hoed

“…Abstract Hundreds of loci have been robustly associated with obesity-related traits, but functional characterization of candidate genes remains a bottleneck. …”
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Whole-Body and Segmental Phase Angles and Cognitive Function in the Older Korean Population: Cross-Sectional Analysis by Jiaren Chen, Jong-Hwan Park, Chien-Yu Lin, Ting-Fu Lai, Du-Ri Kim, Myung-Jun Shin, Eunsoo Moon, Jung Mo Kang, Jong Won Lee, Yoon Jae Cho, Yung Liao, Tae Sik Goh, Jung Sub Lee

“…A positive association was observed between whole-body PhA and cognitive function (bPbPbPbPbPbPbPbP ConclusionsOur findings bolster the emerging evidence of a significant positive correlation between whole-body PhA and cognitive function in our sample, with nuanced relationships observed across different segmental PhAs and cognitive subdomains. …”
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Life cycle CO2 emissions of various transformers under different scenarios with multiple functional units by Chao Liu, Bo Miao, Shu-Zhen Li, Wan-Shui Yu, Qiu-Jie Yuan, Yu-Wei Cao, Yang Yu, Qing Yang

“…Despite extensive research on transformer life cycle carbon emissions, the selection of an appropriate functional unit remains challenging. Many commonly used functional units inadequately reflect transformer functionalities, hindering accurate comparisons across different voltage levels and capacities. …”
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Utilization of dexrazoxane in patients treated with doxorubicin: a retrospective, propensity matched analysis of cardiac function and toxicity by Zachary M. Neiman, Carlo S. Legasto, Alan K. Chin, Tiffany Guan, Brian C. Schulte, Brian C. Schulte

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Predictive value of percutaneous peripheral arterial compliance T in left ventricular diastolic function with coronary artery disease by Wenhao Zhang, Wenhao Zhang, Guoliang Liang, Guoliang Liang, Liang Lv, Xinxin Gu, Xinxin Gu, Qiong Zhang, Ankang Liu, Jiangwei Ma, Jiangwei Ma

“…The study leverages the convenience and accuracy of measuring peripheral arterial sclerosis to facilitate the early detection of diastolic dysfunction, which is instrumental in mitigating and delaying the onset and progression of heart failure, holding significant clinical relevance.MethodsThis research enrolled 556 patients suspected of experiencing Acute Coronary Syndrome (ACS) and stratified them into Groups A, B, C, and D according to the severity of coronary artery stenosis. The diastolic function of the left ventricle was indicated by the relaxation time constant, denoted as T value, which measures the temporal span from the peak rate of left ventricular pressure rise (dp/dt) to the end-diastolic pressure.ResultsThe T value of the left ventricle demonstrated a significant correlation with the Gensini Score and the T values across various peripheral arteries (P &lt; 0.01). …”
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Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study by Owen Griffith, Xiaoxiao Bai, Alexa E. Walter, Michael Gay, Jon Kelly, Wayne Sebastianelli, Linda Papa, Semyon Slobounov

“…Player position affected functional connectivity across a season of football. …”
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Spatial Patterns and Functional Diversity of Nearshore and Offshore Coral-Reef Fish Communities in the South China Sea by Chen Zhang, Simin Hu, Lintao Huang, Xianzhi Lin, Hui Huang, Sheng Liu

“…Significant spatial differences were observed in species composition, functional trait structure, and responses to environmental disturbance. …”
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Post-Lunch Napping as a Strategy to Enhance Physiological Performance and Cognitive Function in Elite Volleyball Players by Özgür Eken, Oguzhan Bozkurt, Musa Türkmen, Ahmet Kurtoglu, Madawi H. Alotaibi, Safaa M. Elkholi

“…Further research is needed to explore long-term effects and variations across other sports.…”
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The impact of low energy availability risk on pre-competition physiological function in Chinese female combat athletes by Yiheng Liang, Yuxuan Li, Yan Chen, Kun Meng, Fanyang Zhou, Yiran Pei, Yong Liu, Junqiang Qiu

“…It is essential for Chinese coaches and sports medicine staff to implement LEA-related nutritional education across all performance levels. Moreover, preventive measures during training are recommended to mitigate the impact of LEA on physiological function during the pre-competition weight loss phase.…”
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Identification of time-varying parameters of a monthly Budyko function in US MOPEX catchments and its implications by Weibo Liu, Pan Liu, Lei Cheng, Xiaojing Zhang, Liting Zhou

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Taxonomic and functional diversities reveal different fish assemblage dynamics of stow net fishery in Haizhou Bay by Guangjie Fang, Yazhou Zhang, Haolin Yu, Chuanxi Chen, Jun Liang, Yanli Tang

“…Significant differences in taxonomic diversity were observed only between two seasons, whereas functional diversity showed significant differences across years, seasons and groups. …”
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