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Neglect and Neurodevelopment: A Narrative Review Understanding the Link Between Child Neglect and Executive Function Deficits
Published 2025-06-01“…Unlike other types of abuse, neglect is characterized by the absence of essential stimuli and caregiving, which are critical for normal brain maturation, particularly in regions involved in executive function. <b>Objective</b>: This narrative review aims to critically explore the neurobiological mechanisms through which early-life neglect impairs the development of executive functions. …”
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Diversity, Composition, and Ecological Function of Endophytic Fungal Communities Associated with <i>Erigeron breviscapus</i> in China
Published 2025-05-01“…Furthermore, FUNGuild was performed to predict the ecological functions of the fungi. <i>Didymella</i> was found to be the most dominant genus across all four tissues, followed by <i>Plectosphaerella</i>, <i>Filobasidium</i>, <i>Cystofilobasidium</i>, and <i>Cladosporium</i>. …”
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DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches
Published 2025-01-01“…This study integrated genome-wide DNA methylation profiles and comorbidity patterns to identify the common biomarkers with multi-functional analytics across the aforementioned five cancer types. …”
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Reveal genomic insights into cotton domestication and improvement using gene level functional haplotype-based GWAS
Published 2025-05-01“…However, few studies have thoroughly analyzed genes, the fundamental and most crucial functional units. Here, we develop an innovative strategy to translate genomic variants into gene-level functional haplotypes (FHs), effectively reducing the interference from complex genome structure and linkage disequilibrium (LD) present in the conventional genetic mapping framework. …”
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Effect of solid-state fermentation on kidney bean flour: Functional properties, mineral bioavailability, and product formulation
Published 2025-04-01“…This research investigated the effects of solid-state fermentation with Aspergillus awamori (MTCC 548) on the mineral bioavailability, structural characteristics, and functional attributes of kidney bean flour across different fermentation durations (24–96 h). …”
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NR5A1 and cell population heterogeneity: Insights into developmental and functional disparities and regulatory mechanisms
Published 2025-01-01“…Additionally, NR5A1‐positive cells in these tissues exhibit developmental and functional heterogeneity. Methods This review summarizes recent knowledge on the relationships between physiological functions and gene cascades regulated by NR5A1 in each tissue. …”
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The effect of active exercise and relaxation-based on psychological well-being, functional ability, and independence in the older adults
Published 2025-06-01“…Functional gains were also noted in lower-body strength, flexibility, and hand grip performance. …”
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Cognitive Function Tests: Application of MMSE and MoCA in Various Clinical Settings- a Brief Overview
Published 2024-11-01“… Introduction: Cognitive impairment can emerge as part of aging or from conditions affecting brain function, such as stroke, brain tumors, delirium, and neurodegenerative diseases. …”
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Altered neural oscillation patterns and functional connectivity in postherpetic neuralgia: evidence from resting-state EEG
Published 2025-07-01“…This study aimed to systematically assess the neural oscillatory activity and functional connectivity patterns in patients with PHN using resting-state electroencephalography (EEG). …”
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A nomogram model incorporating blood biomarkers predicts 3-week functional outcomes in stroke patients
Published 2025-05-01“…Discrimination and calibration values of the nomogram were analyzed, and its utility was assessed using decision curve analysis.ResultsFour blood biomarkers, including PT (OR = 1.45, 95% CI: 1.05–2.12), FIB (OR = 1.49, 95% CI: 1.14–2.00), RBG (OR = 1.20, 95% CI: 1.03–1.40), and UA (OR = 1.00, 95% CI: 0.99–1.00) were independent predictors of the 3-week functional outcomes after a stroke. The nomogram incorporating these biomarkers demonstrated moderate discriminative ability (AUC values = 0.714, 95%CI: 0.641–0.786), with satisfactory calibration and positive net benefit on DCA across clinically relevant threshold probabilities.ConclusionWe developed a pragmatic nomogram integrating readily available blood biomarkers to predict 3-week functional outcomes in stroke patients. …”
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Measuring functioning and disability in Korea: comparing general and dedicated surveys using the ICF as a reference framework.
Published 2025-01-01“…The ICF categories b152 emotional functions and b130 energy and drive functions were the most frequently covered across all the surveys. …”
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Depth-electrode stimulation and concurrent functional MRI in humans: Factors influencing heating with body coil transmission
Published 2025-01-01“…Electrical-stimulation fMRI (es-fMRI) combines direct stimulation of the brain via implanted electrodes with simultaneous rapid functional magnetic resonance imaging of the evoked response. …”
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Validating Data Interpolation Empirical Orthogonal Functions Interpolated Soil Moisture Data in the Contiguous United States
Published 2025-06-01“…Data Interpolation Empirical Orthogonal Functions (DINEOF+) is an interpolation technique that uses singular value decomposition (SVD) to address missing data problems. …”
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Covariance-based decoding reveals a category-specific functional connectivity network for imagined visual objects
Published 2025-05-01“…In this magnetoencephalography study, we used a minimally constrained experimental paradigm wherein imagery categories were prompted using visual word cues only, and we decoded face versus place imagery based on their underlying functional connectivity patterns as estimated from the spatial covariance across brain regions. …”
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Investments for effective functionality of health systems towards Universal Health Coverage in Africa: A scoping review.
Published 2022-01-01“…We inventoried these effective interventions for improving health systems functionality in Africa. Further analyses could deepen understanding of how such interventions differ in their incorporation of evidence for potential scale across African countries.…”
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Comprehensive bioinformatic analysis reveals prognostic significance and functional insights of candidate gene expression in colorectal cancer
Published 2025-02-01“…Furthermore, we identified nine candidate genes (CDH11, COL1A1, COL1A2, COL5A1, COL5A2, FAP, SPARC, SULF1, and THY1) as potential crosstalk genes across various datasets. Notably, eight of these candidate genes exhibited a significant correlation with poor overall survival (OS) and recurrence-free survival (RFS) in CRC patients, suggesting their potential as prognostic biomarkers. …”
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Functional role of cell classes in monkey prefrontal cortex after learning a working memory task
Published 2025-05-01“…Neuronal response modulation varied heterogeneously across these cell classes after training and performing active tasks. …”
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Is Placental Mitochondrial Function a Regulator that Matches Fetal and Placental Growth to Maternal Nutrient Intake in the Mouse?
Published 2015-01-01“…<h4>Background</h4>Effective fetal growth requires adequate maternal nutrition coupled to active transport of nutrients across the placenta, which, in turn requires ATP. …”
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