Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study by Jeanne M. McCaffery, Andrea Anderson, Mace Coday, Mark A. Espeland, Amy A. Gorin, Karen C. Johnson, William C. Knowler, Candice A. Myers, W. Jack Rejeski, Helmut O. Steinberg, Andrew Steptoe, Rena R. Wing

“…Here, we examined the relationship of loneliness with disability, objective physical function, and other health outcomes in older individuals with type 2 diabetes and overweight or obesity. …”
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Functionalized Graphene Quantum Dots (FGQDs): A review of their synthesis, properties, and emerging biomedical applications by Abida Jan, Midhat Batool, Samreen Akram, Akhtar Hussain Malik, Waheed Ahmad Khanday, Waseem A. Wani, Rayees Ahmad Sheikh, Jahangir Ahmad Rather, Palanisamy Kannan

“…As nanoscale fragments of graphene rich in electrons, GQDs offer enhanced capabilities that elevate their potential across a wide range of applications. This review paper delves into the synthesis, characterization, and applications of functionalized graphene quantum dots (FGQDs), which exhibit exceptional photoelectronic properties resulting from quantum confinement and edge effects. …”
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Impact of physical inactivity and sedentary behaviour on functional constipation in children and adolescents: a systematic review by Marc A Benninga, Morris Gordon, Shaman Rajindrajith, Wathsala Hathagoda, Shanaz Adil, Chandrani Kuruppu

“…Objective Lack of physical activity (PA) and sedentary behaviour (SB) have emerged as critical global health concerns in children and are believed to be associated with functional constipation (FC). The present study aims to explore this potential association.Design A comprehensive search of PubMed, Scopus, Web of Science, Embase, Cochrane Library and PsycInfo databases was conducted through 2023 using terms related to constipation and PA and SB in ages 0–18 years. …”
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De Novo transcriptome assembly of Diaprepes abbreviatus: foundations for functional genomics and targeted pest management by Lamiaa M. Mahmoud, Tejbhan Saini, Nabil Killiny

“…Additionally, genes related to mitochondrial function, muscle structure, and detoxification pathways exhibited clear sex-specific expression. …”
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Systematic analysis and functional characterization of the chitinase gene family in Fagopyrum tataricum under salt stress by Qingqing Li, Yongyi Yang, Xue Bai, Lun Xie, Suzhen Niu, Biao Xiong

“…Results This study analyzed their phylogenetic relationships, conserved motifs, gene structures, syntenic relationships, physiological functions, and biochemical properties. This research identified 26 FtCHIs and examined their expression patterns under different salt stress conditions and across various tissues. …”
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Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences. by Lingyu Zhan, Jiajin Li, Brandon Jew, Jae Hoon Sul

“…Differential expressions between AD patients and controls of these three identified genes were further examined by incorporating scRNA-Seq data from 48 post-mortem brain samples and demonstrated distinct expression patterns across cell types. Taken together, our results demonstrated strong rare-variant effect in the endocytic pathway on AD risk and progression and functional effect of gene expression alteration in both bulk and single-cell resolution, which may bring more insight and serve as valuable resources for future AD genetic studies, clinical research, and therapeutic targeting.…”
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Real-world goal-directed behavior reveals aberrant functional brain connectivity in children with ADHD. by Liya Merzon, Sofia Tauriainen, Ana Triana, Tarmo Nurmi, Hanna Huhdanpää, Minna Mannerkoski, Eeva T Aronen, Mikhail Kantonistov, Linda Henriksson, Emiliano Macaluso, Juha Salmi

“…Functional connectomics is a popular approach to investigate the neural underpinnings of developmental disorders of which attention deficit hyperactivity disorder (ADHD) is one of the most prevalent. …”
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The Effects of Multicomponent Training on Clinical, Functional, and Psychological Outcomes in Cardiovascular Disease: A Narrative Review by Luca Poli, Alessandro Petrelli, Francesco Fischetti, Stefania Morsanuto, Livica Talaba, Stefania Cataldi, Gianpiero Greco

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In Vitro Prevention of Salmonella Lipopolysaccharide-Induced Damages in Epithelial Barrier Function by Various Lactobacillus Strains by Chun-Yan Yeung, Jen-Shiu Chiang Chiau, Wai-Tao Chan, Chun-Bin Jiang, Mei-Lien Cheng, Hsuan-Liang Liu, Hung-Chang Lee

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Computer-assisted rehabilitation system in the use of motor function recovery: A protocol for scoping review. by Jun Fan, Xuqiang Wei, Yue Yao, Yibang Jiang, Cankun Xin, Ling Feng

“…To address this challenge, computer-assisted rehabilitation systems (CARS) have emerged as innovative tools for facilitating motor function recovery. However, the rapid proliferation of diverse CARS modalities-encompassing novel technical approaches, interdisciplinary integrations, and heterogeneous clinical applications-has resulted in a fragmented and poorly delineated research landscape. …”
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Functional and microbiological effects of a microencapsulated probiotic consortium on the ruminal microbiota in vivo and in vitro systems by Johanna Marcela Urán Velásquez, Mauricio Agudelo Rendón, Mariana Zapata, Wilyer García Arboleda, Sara Echeverri, Juan Camilo Arroyave Manco, Koen Venema, Juan Vasquez

“…Over time, both systems were analysed for short-chain fatty acid (SCFA) production, microbial composition and functionality using next-generation sequencing. Physicochemical parameters were consistent across both systems and the inoculum, with an increase in propionate concentration observed. …”
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Potential role of N6-methyladenosine modification in circular RNA biogenesis and function in the inflammatory responses by Heedoo Lee, Heedoo Lee, Leo Chen, Yang Jin

“…Circular RNA (circRNA) refers to a single-stranded RNA molecule with a circular structure that exists across a wide range of organisms, including eukaryotes and prokaryotes. …”
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Investigating the impact of sleep quality on cognitive functions among students in Tokyo, Japan, and London, UK by Joshua Ampofo, Binghai Sun, Geoffrey Bentum-Micah, Geoffrey Bentum-Micah, Li Qinggong, Wang Changfeng, Le Guoan, Qian Xusheng

“…At the same time, cognitive tests, including the Rey Auditory Verbal Learning Test and the Stroop Test, evaluated memory, attention, problem-solving, and executive functions.ResultsSignificant negative correlations emerged between PSQI scores and cognitive performance, indicating that poorer sleep quality correlated with diminished cognitive abilities across domains. …”
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Spatio‐Temporal Dynamics of Invasive Spartina Alterniflora and Its Functional Traits' Responding to Hydro‐Meteorology by Bolin Fu, Bingyan Yuan, Hang Yao, Weiwei Sun, Mingming Jia, Zuofang Yao, Yeqiao Wang

“…Finally, we explored the phenological rhythm of S. alterniflora functional traits, and clarified the response mechanisms of its vegetation functional traits to hydro‐meteorological factors. …”
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Incident arrhythmias in relation to ventilatory parameters and pulmonary disease: evidence from two prospective cohort studies by Yun-Jiu Cheng, Li-Ping Qu, Yi-Jian Liao, Si-Long Lu, Mei-Ping Lin, Qian He, Jin-Bo Fu, Jun-Chi Li, Wen-Juan Duan, Li-Juan Liu

“…Conclusions Reduced pulmonary function suggested independent associations with incident arrhythmias across supraventricular, ventricular, and conduction system pathologies in two historical cohorts. …”
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Advances in ethological approaches to explore rodent vocal communication by Ali Abud, Ali Abud, Yihan Wang, Yihan Wang, Yihan Wang, Rechuma Hafter, Ehsan Tavakoli, Christina Wu, Senadee Atapattu, Ahmed Raza, Mohammad Ali, Ali Al-Hadi, Hamza Khalid, Rehmat K. Sukhija, Tobias Stoodley, Alisha Joshi, Samar Joshi, Samar Joshi, Morgan L. Gustison

“…We found that rodent vocal communication studies varied across ethological perspectives, with more studies carried out on vocal mechanisms and adaptive functions than on development and evolution. …”
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Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1 by Lindsay N. Alfano, Megan A. Iammarino, Natalie F. Reash, Linda P. Lowes, Lindsay Pietruszewski, Kathleen Adderley, Lauren Humphrey, Audrey B. Knight, Christopher L. Steiner, Melissa A. Smith, Zarife Sahenk, Anne M. Connolly, Momen Almomen, Eleonora S. D'Ambrosio, Nathan Peck, Allison Peck

“…Differences in lower and upper extremity involvement were noted across variant groups. Performance of functional COA was reliable and safe within and across onsite and remote testing environments (ICC > 0.7, p < 0.001). …”
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The prevalence and correlates of low sexual functioning in women on hemodialysis: A multinational, cross-sectional study. by Valeria Saglimbene, Patrizia Natale, Suetonia Palmer, Marco Scardapane, Jonathan C Craig, Marinella Ruospo, Letizia Gargano, Giuseppe Lucisano, Marietta Török, Eduardo Celia, Rubén Gelfman, Anna Bednarek-Skublewska, Jan Dulawa, Paul Stroumza, Miguel Leal, Domingo Del Castillo, Angelo Marco Murgo, Staffan Schon, Charlotta Wollheim, Jörgen Hegbrant, Giovanni F M Strippoli

“…In conclusion, women in hemodialysis reported scores consistent with marked low sexual functioning across a range of domains; the low functioning appeared to be associated with comorbidity.…”
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Effect of curcumin incorporation on the structural and functional properties of oleogels structured with rice bran or carnauba wax by Md Jannatul Ferdaus, Jabarius Allah Malik Jones, Roberta Claro da Silva

“…Significant differences (p < .05) were observed across formulations in oil retention, textural properties, and oxidative stability. …”
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Loss-function-of a UMP kinase leads to impaired chloroplast development and photosynthesis efficiency in cucumber by Ming Pan, Cancan Xia, Shenao Gu, Huanle He, Gang Wang, Yiqun Weng, Jian Pan, Junsong Pan

“…The present findings highlight the crucial contribution of CsUMPK to photosynthetic efficiency and chloroplast formation, offering insights into the molecular basis of photosynthesis across plant species.…”
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