Determination of resonances in Gamow window for 12C+12C fusion reaction via thick-target inverse kinematics method by Weike Nan, Youbao Wang, Jun Su, Yaode Sheng, Richard James deBoer, Yuqiang Zhang, Luyang Song, Fuqiang Cao, Chen Chen, Chao Dong, Yunju Li, Zhihong Li, Gang Lian, Wei Nan, Yangping Shen, Na Song, Shengquan Yan, Seng Zeng, Bing Guo, Weiping Liu

“…In particular, branching ratios of the dominant four decay channels are estimated across the entire Gamow window of the 12C+12C fusion reactions. …”
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Dynamic hierarchical ligand anisotropy for competing macrophage regulation in vivo by Kanghyeon Kim, Sunhong Min, Ramar Thangam, Kyong-Ryol Tag, Hyun-Jeong Lee, Jeongyun Heo, Hwapyung Jung, Thet Thet Swe, Iman Zare, Guosheng Song, Alireza Hassani Najafabadi, Junmin Lee, Hyun-Do Jung, Jong Seung Kim, Sunghoon Hur, Hyun-Cheol Song, Sung-Gyu Park, Kunyu Zhang, Pengchao Zhao, Liming Bian, Se Hoon Kim, Juyoung Yoon, Jae-Pyoung Ahn, Hong-Kyu Kim, Heemin Kang

“…Diverse connective tissues exhibit hierarchical anisotropic structures that intricately regulate homeostasis and tissue functions for dynamic immune response modulation. In this study, remotely manipulable hierarchical nanostructures are tailored to exhibit multi-scale ligand anisotropy. …”
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Quantifying the national responsibilities for the conservation of transboundary migratory species Siberian ibex by Jingwen Xu, Yingying Zhuo, Sabina Koirala, Muhammad Zafar Khan, Shamshidin Abduriyim, Chagsaldulam Odonjavkhlan, Vladislav Vinogradov, Ruidong Zhang, Baolin Zhang, Kathreen Ruckstuhl, António Alves da Silva, Joana Alves, Alice Hughes, Jiajia Liu, Muyang Wang, Weikang Yang

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Exploring salinity adaptation in teleost fish, focusing on omics perspectives on osmoregulation and gut microbiota by Evodia Moses Mkulo, Evodia Moses Mkulo, Evodia Moses Mkulo, Lukman Iddrisu, Mpwaga Alatwinusa Yohana, Anna Zheng, Anna Zheng, Anna Zheng, Jiahao Zhong, Jiahao Zhong, Jiahao Zhong, Minxuan Jin, Minxuan Jin, Minxuan Jin, Felix Danso, Linjuan Wang, Linjuan Wang, Linjuan Wang, Huijuan Zhang, Huijuan Zhang, Huijuan Zhang, Baogui Tang, Baogui Tang, Baogui Tang, Hui Zhou, Hui Zhou, Hui Zhou, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Jiansheng Huang, Jiansheng Huang, Jiansheng Huang, Bei Wang, Bei Wang, Bei Wang, Zhongliang Wang, Zhongliang Wang, Zhongliang Wang, Zhongliang Wang

“…Gut microbiota analysis highlights microbial diversity in regulating osmoregulatory functions, emphasizing microbiota’s role in resilience. …”
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Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19 by Vasiliy E. Akimov, Dmitriy I. Tychinin, Olga A. Antonova, Abusaid M. Shaymardanov, Maria D. Voronina, Kseniia A. Deinichenko, Oleg D. Fateev, Vladimir S. Yudin, Sergey M. Yudin, Vladimir E. Mukhin, Svetlana V. Romanova, Aleksandra I. Nekrasova, Anastasia S. Zhdanova, Anastasia V. Tsypkina, Ivan S. Vladimirov, Antonida V. Makhotenko, Anton A. Keskinov, Sergey A. Kraevoy, Ekaterina A. Snigir, Dmitry V. Svetlichnyy, Veronika I. Skvortsova

“…COVID-19 is characterized by systemic pro-inflammatory shifts with the development of serious alterations in the functioning of the immune system. Investigations of the gene expression changes accompanying the infection state provide insight into the molecular and cellular processes depending on the sickness severity and virus variants. …”
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Beyond the closed-forest paradigm: Cross-scale vegetation structure in temperate Europe before the late-Quaternary megafauna extinctions by Elena A. Pearce, Florence Mazier, Charles W. Davison, Oliver Baines, Szymon Czyżewski, Ralph Fyfe, Krzysztof Bińka, Steve Boreham, Jacques-Louis de Beaulieu, Cunhai Gao, Wojciech Granoszewski, Anna Hrynowiecka, Małgorzata Malkiewicz, Tim Mighall, Bożena Noryśkiewicz, Irena Agnieszka Pidek, Jaqueline Strahl, Hanna Winter, Jens-Christian Svenning

“…Using LOVE (Local Vegetation Estimates) and REVEALS (Regional Estimates of VEgetation Abundance from Large Sites) models, this study reconstructs vegetation patterns across local (∼9 km²) and regional (∼100 km²) scales. …”
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Faster decline of very prodromal dementia with Lewy bodies when amyloid positive by Frédéric Blanc, Vincent Bouteloup, Claire Paquet, Marie Chupin, Florence Pasquier, Audrey Gabelle, Mathieu Ceccaldi, Paulo Loureiro deSousa, Pierre Krolak‐Salmon, Renaud David, Clara Fischer, Jean‐François Dartigues, David Wallon, Olivier Moreaud, Mathilde Sauvée, Catherine Belin, Claire Roubaud Baudron, Anne Botzung, Alix Ravier, Catherine Demuynck, Izzie Namer, Marie‐Odile Habert, Olivier Bousiges, Benoît Schorr, Candice Muller, Nathalie Philippi, Geneviève Chêne, Benjamin Cretin, Jean‐François Mangin, Carole Dufouil

“…RESULTS In the Pro‐DLB and Pro‐DLB+AD groups, Aβ+ patients had more cognitive and functional decline than the Aβ– patients. In the Pro‐AD and NS groups, Aβ+ patients had more functional decline. …”
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Enhancing Network Slicing Architectures With Machine Learning, Security, Sustainability and Experimental Networks Integration by Joberto S. B. Martins, Tereza C. Carvalho, Rodrigo Moreira, Cristiano Bonato Both, Adnei Donatti, Joao H. Correa, Jose A. Suruagy, Sand L. Correa, Antonio J. G. Abelem, Moises R. N. Ribeiro, Jose-Marcos S. Nogueira, Luiz C. S. Magalhaes, Juliano Wickboldt, Tiago C. Ferreto, Ricardo Mello, Rafael Pasquini, Marcos Schwarz, Leobino N. Sampaio, Daniel F. Macedo, Jose F. De Rezende, Kleber V. Cardoso, Flavio De Oliveira Silva

“…The Slicing Future Internet Infrastructures (SFI2) architecture proposal explores the gap resulting from the diversity of NS architectures target domains by proposing a new NS reference architecture with a defined focus on integrating experimental networks and enhancing the NS architecture with Machine Learning (ML) native optimizations, energy-efficient slicing, and slicing-tailored security functionalities. The SFI2 architectural main contribution includes the utilization of the slice-as-a-service paradigm for end-to-end orchestration of resources across multi-domains and multi-technology experimental networks. …”
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Characterizing microglial heterogeneity in autophagy impairment of Paraquat-induced Parkinson’s disease-like neurodegeneration by Yu Zhang, Yihua Jiang, Zhen Yu, Yinhan Li, Zhiyu Zhang, Fuli Zheng, Hong Hu, Guangxia Yu, Zhenkun Guo, Siying Wu, Wenya Shao, Huangyuan Li

“…Using single-cell RNA sequencing (scRNA-seq), we elucidated the autophagy-related transcriptomic landscapes in this model, identifying microglia as the central cell type associated with PQ-induced autophagy across all brain cell types. Additionally, microglial subtypes in the PQ-exposed model exhibited significant heterogeneity in gene expression characteristics, biological functions, and roles in autophagic regulation. …”
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Methylphenidate versus placebo for fatigue in patients with advanced cancer: the MePFAC randomised controlled trial by Patrick Stone, Ollie Minton, Alison Richardson, Peter Buckle, Zinat E Enayat, Louise Marston, Nick Freemantle

“…Functional Assessment of Chronic Illness Therapy – Fatigue Scale score was nominally statistically significantly higher (better) in methylphenidate group across duration of study [Diff 2.20 (95% confidence interval 0.39 to 4.01)] but did not reach the minimal clinically important difference (5 points). …”
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Machine learning-based prediction model for lung ischemia-reperfusion injury: insights from disulfidptosis-related genes by Yanpeng Zhang, Yanpeng Zhang, Yanpeng Zhang, Jingyang Sun, Jingyang Sun, Jingyang Sun, Yihan Lin, Yihan Lin, Yihan Lin, Rongxuan Jiang, Rongxuan Jiang, Rongxuan Jiang, Niuniu Dong, Niuniu Dong, Niuniu Dong, Huanhuan Dong, Huanhuan Dong, Huanhuan Dong, Peng Li, Peng Li, Peng Li, Jinteng Feng, Jinteng Feng, Jinteng Feng, Zijiang Zhu, Guangjian Zhang, Guangjian Zhang, Guangjian Zhang

“…Differential expressed analysis and functional enrichment analysis were conducted to identify key genes associated with lung transplant IRI. …”
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Smartphone language features may help identify adverse post-traumatic neuropsychiatric sequelae and their trajectories by Lisa Vizer, Jennifer Pierce, Yinyao Ji, Meredith A. Bucher, Mochuan Liu, Lyle Ungar, Salvatore Giorgi, Zhaopeng Xing, Stacey L. House, Francesca L. Beaudoin, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Donglin Zeng, Laura T. Germine, Kenneth A. Bollen, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Brian J. O’Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce, Steven E. Harte, Ronald C. Kessler, Karestan C. Koenen, Samuel A. McLean, Xinming An

“…Language features derived from usual smartphone use can convey important information about health, functioning, and recovery following a traumatic event. …”
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The comprehensive transcriptomic atlas of porcine immune tissues and the peripheral blood mononuclear cell (PBMC) immune dynamics reveal core immune genes by Qingyao Zhao, Jiahao Wang, Fuping Ma, Quanzhen Chen, Huatao Liu, Jinyan Yang, Siqian Chen, Yongjie Tang, Siyuan Mi, Lulu Wang, Xini Wang, Guohong Liu, Kai Xing, Ying Yu, Chuduan Wang

“…Results WGCNA analysis identified core immune genes across six immune tissues (bone marrow, jejunum, lymph node, PBMC, spleen, thymus) in Landrace pigs, which are also crucial for the development of PBMCs. …”
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The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol by Natasha Berthold, Casey M. MacDermod, Laura M. Thornton, Richard Parker, Shantal Anid Cortés Morales, Liv Hog, Hannah L. Kennedy, Jerry Guintivano, Patrick F. Sullivan, James J. Crowley, Jessica S. Johnson, Andreas Birgegård, Bengt T. Fundín, Emma Frans, Jiayi Xu, Michaela Pettie “Ngāti Pūkenga”, Allison L. Miller, Mariana Valdez Aguilar, Sarah Barakat, Mohamed Abdulkadir, Jennifer P. White, Janne T. Larsen, Elsie Trujillo, Bertha Winterman, Ruyue Zhang, Rachel Lawson, Stephen Wonderlich, Joseph Wonderlich, Lauren M. Schaefer, Philip S. Mehler, Judy Oakes, Marina Foster, Jennifer Gaudiani, Eva Trujillo Chi Vacuán, Emilio J. Compte, Liselotte V. Petersen, Zeynep Yilmaz, Nadia Micali, Jennifer Jordan, Martin A. Kennedy, Sarah Maguire, Laura M. Huckins, Yi Lu, Lisa Dinkler, Nicholas G. Martin, Cynthia M. Bulik

“…Discussion EDGI2 is a global expansion of the EDGI study to increase sample size, increase participant representation across multiple ancestral backgrounds, and to include ARFID. …”
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Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases by Jia-Hao Wang, Shan-Shan Dong, Wei Huang, Hao-An Wang, Shao-Shan Liu, Xiaoyi Ma, Ren-Jie Zhu, Wei Shi, Hao Wu, Ke Yu, Tian-Pei Zhang, Cong-Ru Wang, Yan Guo, Hanzhong Xue, Tie-Lin Yang

“…PWAS was performed using the Functional Summary-based Imputation (FUSION) framework to identify protein-disease associations. …”
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EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis by Lianlei Wang, Xinyu Yang, Sen Zhao, Pengfei Zheng, Wen Wen, Kexin Xu, Xi Cheng, Qing Li, Anas M Khanshour, Yoshinao Koike, Junjun Liu, Xin Fan, Nao Otomo, Zefu Chen, Yaqi Li, Lulu Li, Haibo Xie, Panpan Zhu, Xiaoxin Li, Yuchen Niu, Shengru Wang, Sen Liu, Suomao Yuan, Chikashi Terao, Ziquan Li, Shaoke Chen, Xiuli Zhao, Pengfei Liu, Jennifer E Posey, Zhihong Wu, Guixing Qiu, DISCO study group (Deciphering Disorders Involving Scoliosis & COmorbidities), Shiro Ikegawa, James R Lupski, Jonathan J Rios, Carol A Wise, Jianguo T Zhang, Chengtian Zhao, Nan Wu

“…Subsequently, we mapped these loci to candidate genes using either location-based or function-based strategies. To further substantiate our findings, we verified the enrichment of variants within these candidate genes across several large IS cohorts encompassing Chinese, East Asian, and European populations. …”
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Abstract 073: Thrombectomy Alone Versus Bridging Intravenous Alteplase in A US Population: Regression Discontinuity Analysis by Ngoc Mai Le, Youngran Kim, Sergio Salazar‐Marioni, Arash Niktabe, Anjan Ballekere, Rania Abdelkhaleq, Ananya Iyyangar, Hussain Azeem, Diogo Haussen, Jonathan Grossberg, Jaydevsinh Dolia, Aqueel Pabaney, Mahmoud Mohammaden, Shahram Majidi, Johanna T. Fifi, Thanh Nguyen, Mohamad Abdalkader, Piers Klein, Rebecca Sugg, Ameer Hassan, Wondwossen Tekle, David Liebeskind, Italo Linfante, Hamzah Saei, Gabrielle Valestin, Santiago Ortega‐Gutierrez, James Siegler, Brijesh Mehta, Guillermo Linares, Mouhammad Jumaa, Joy Sessa, Sunil Sheth, Raul Nogueira

“…Methods From the prospectively collected SVIN Registry encompassing all consecutive patients treated with EVT from 12 centers across the US, we identified patients from 12/2010 – 12/2021. …”
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Prognostic and immunological implications of cathepsin Z overexpression in prostate cancer by Junyue Tao, Junyue Tao, Junyue Tao, Yiding Chen, Yiding Chen, Yiding Chen, Xiaokang Bian, Xiaokang Bian, Xiaokang Bian, Tingting Cai, Tingting Cai, Tingting Cai, Changhao Song, Changhao Song, Changhao Song, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang, Zongyao Hao, Zongyao Hao, Zongyao Hao, Jialing Meng, Jialing Meng, Jialing Meng, Qintao Ge, Qintao Ge, Jun Zhou, Jun Zhou, Jun Zhou

“…Gene Set Enrichment Analysis was performed to identify potential signaling pathways involved.ResultsCTSZ is highly expressed in PCa tissues and is associated with higher Gleason scores, advanced T/N staging, and poor prognosis. Survival analyses across multiple cohorts indicate that high CTSZ expression predicts shorter progression-free survival and overall survival. …”
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Effects of antagonistic network-targeted tDCS on brain co-activation patterns depends on the networks’ electric field: a simultaneous tDCS-fMRI study by Hechun Li, Hongru Shi, Sisi Jiang, Changyue Hou, Haonan Pei, Hanxi Wu, María Luisa Bringas Vega, Gang Yao, Dezhong Yao, Cheng Luo

“…Material and method: The current study utilized simultaneous network-targeted transcranial direct current stimulation(tDCS) and functional magnetic resonance imaging (fMRI) to investigate the effects of tDCS targeting antagonistic networks on brain dynamics. …”
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Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration by Macsue Jacques, Shanie Landen, Adam P. Sharples, Andrew Garnham, Ralf Schittenhelm, Joel Steele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, Sarah E. Alexander, Cassandra Smith, Carlie Bauer, Mary N. Woessner, Itamar Levinger, Andrew E. Teschendorff, Linn Gillberg, Ida Blom, Jørn Wulff Helge, Nicholas R. Harvey, Larisa M. Haupt, Lyn R. Griffiths, Atul S. Deshmukh, Kirsi H. Pietiläinen, Päivi Piirilä, Robert A.E. Seaborne, Marie Klevjer, Anja Bye, Ulrik Wisløff, Bernadette Jones-Freeman, Nir Eynon

“…We identified distinctive signatures associated with maximal oxygen consumption (VO2max), and multi-omics integration uncovered five key genes as robust exercise markers across layers, with transcription factors functioning as activators, synergizing with DNA methylation to regulate gene expression. …”
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