-
15421
Evaluating the effect of nutritional support in geriatric inpatients classified by the GLIM criteria
Published 2025-08-01“…Setting: This study was conducted from September 2020 to December 2022 across 28 geriatric centers in China. Participants: A total of 862 patients aged ≥65 years were included. …”
Get full text
Article -
15422
Deuterium plasma-driven permeation in chemical vapor deposition tungsten-copper composite
Published 2025-01-01“…The length of the segment was in line with the experimental observation in the Cu-entry region of CVD-W near the CVD-W/Cu interface. Density functional theory calculations confirmed that the presence of Cu in W could reduce the HI solution energy in W. …”
Get full text
Article -
15423
Alzheimer's disease: a comprehensive review of epidemiology, risk factors, symptoms diagnosis, management, caregiving, advanced treatments and associated challenges
Published 2024-12-01“…These pathological changes lead to widespread neuronal damage, significantly impacting daily functioning and quality of life.ObjectiveThis comprehensive review aims to explore various aspects of Alzheimer's disease, including its epidemiology, risk factors, clinical presentation, diagnostic advancements, management strategies, caregiving challenges, and emerging therapeutic interventions.MethodsA systematic literature review was conducted across multiple electronic databases, including PubMed, MEDLINE, Cochrane Library, and Scopus, from their inception to May 2024. …”
Get full text
Article -
15424
Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort
Published 2024-07-01“…Introduction: The National Registry of Rare Kidney Diseases (RaDaR) collects data from people living with rare kidney diseases across the UK, and is the world’s largest, rare kidney disease registry. …”
Get full text
Article -
15425
Plasma testosterone concentration is correlated with circulating immune cell abundance in transgender young people on gender-affirming hormone treatment
Published 2025-07-01“…Immune cell abundance was compared across experimental groups, and correlated with plasma concentrations of oestradiol and testosterone using multiple regression models. …”
Get full text
Article -
15426
Right-restricting measures implemented by Public Health Surveillance services during the COVID-19 pandemic: a systematic review protocol
Published 2025-07-01“…Introduction The COVID-19 pandemic’s unprecedented nature has exposed significant vulnerabilities in most public health systems and highlighted the importance of coordinated responses across various levels of government. A global debate emerged on the types of health measures necessary to curb the rapid spread of contagious and/or lethal diseases. …”
Get full text
Article -
15427
Association between somatic microsatellite instability, hypermutation status, and specific T cell subsets in colorectal cancer tumors
Published 2024-12-01“…However, the universality of this response across T cell subtypes with distinct functions is unknown.MethodsIncluding 1,236 CRC tumors from three observational studies, we conducted in-situ T cell profiling using a customized 9-plex (CD3, CD4, CD8, CD45RA, CD45RO, FOXP3, KRT, MKI67, and DAPI) multispectral immunofluorescence assay. …”
Get full text
Article -
15428
Effects of lifestyle interventions on mental health in children and adolescents with overweight or obesity: a systematic review and meta-analysisResearch in context
Published 2025-03-01“…Lifestyle interventions are defined as structured programs that promote health-related behavioural changes across diverse domains, such as physical activity, dietary adjustments, cognitive training, and psychosocial support. …”
Get full text
Article -
15429
Hybrid Integration of a Beam-Steering Leaky-Wave Antenna and Power Amplifier MMIC Using UPD Printing in 220 to 325 GHz Range
Published 2025-01-01“…The hybrid assembly achieves a reflection coefficient of less than -10 dB and a peak gain of up to 26 dBi across the sub- THz range. The beamsteering functionality of the hybrid assembly is successfully validated only in the forward quadrant due to measurement restrictions in the backward quadrant. …”
Get full text
Article -
15430
Astaxanthin ameliorates benzalkonium chloride–induced dry eye disease through suppressing inflammation and oxidative stress via Keap1‐Nrf2/HO‐1 signaling pathways
Published 2025-06-01“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were conducted to elucidate the functions of pivotal targets within the protein–protein interaction network. …”
Get full text
Article -
15431
Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons
Published 2025-06-01“…Next, to understand its functional role, kininogen was overexpressed in the hippocampal CA1 area via its AAV-mediated gene delivery, and bradykinin was administered through the fourth ventricle in mice. …”
Get full text
Article -
15432
Long noncoding RNA LINC00339 promotes osteoporosis development via modulating of regulator CDC42 by binding PARP1
Published 2025-12-01“…Results: This study demonstrated significant upregulation of LINC00339 in bone tissue specimens derived from osteoporosis patients compared to healthy controls. Functional analyses revealed that LINC00339 dysregulation exhibited an inverse correlation with osteogenic differentiation capacity across multiple osteoblast cell models. …”
Get full text
Article -
15433
Identifying Heat Adaptability QTLs and Candidate Genes for Grain Appearance Quality at the Flowering Stage in Rice
Published 2025-03-01“…We identified 25 QTLs associated with grain length (GL), grain width (GW), and grain chalkiness (GC) under heat stress across 10 chromosomes in the three rice populations (full, indica, and japonica). …”
Get full text
Article -
15434
Demand and Influencing factors for community health services during chemotherapy of patients with advanced cancer
Published 2024-06-01“…Conclusion: Patients with advanced cancer undergoing chemotherapy have specific demands for community health services across psychological, medical care, and social support dimensions, influenced by factors such as age, educational level, and household income. …”
Get full text
Article -
15435
-
15436
Promoting the Integration of Public Perspective into Urban Design Decision-Making Based on Crowdsourced Visual Perception Method
Published 2025-05-01“…It systematically investigates how these methods, across key urban design decision-making stages — data collection, data analysis, and scheme generation — facilitate the deep integration of public perspectives into design decisions through specific pathways and mechanisms. …”
Get full text
Article -
15437
-
15438
Unveiling conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling
Published 2025-02-01“…In the blood of people living with HIV, ARF-derived peptides elicit potent poly-functional T cell responses mediated by both CD4+ and CD8+ T cells. …”
Get full text
Article -
15439
Intervention effects of greenspace exposure on human microbiota: A randomized controlled trial in Chinese young adults
Published 2025-05-01“…Differences in microbial alpha-diversity and composition across various groups were tested using Wilcoxon test and permutational multivariate analysis of variance, respectively. …”
Get full text
Article -
15440
Genome-Wide Association Study of Brown Rice Weight Identifies an RNA-Binding Protein Antagonistically Regulating Grain Weight and Panicle Number
Published 2025-07-01“…Among seven consistently detected loci across experimental replicates, four were not co-localized with previously reported genes associated with BRW or GW traits. …”
Get full text
Article