Genome-wide identification and characterization of the Lateral Organ Boundaries Domain (LBD) gene family in nine Rosaceae species and expression pattern in Prunus mume by Weichao Liu, Xiaoyu Guo, Tangchun Zheng, Xue Li, Sagheer Ahmad, Jia Wang, Qixiang Zhang, Tangren Cheng

“…Our studies offer important data about the development of the LBD family in Rosaceae and the subsequent validation of LBDs' functional genes in P. mume.…”
Get full text

Ecological Dynamics of Forest Stands with <i>Castanopsis argentea</i> (Blume) A.DC. in a Mountain Ecosystem: Vegetation Structure, Diversity, and Carbon Stock Under Tourism Pressur... by Reny Sawitri, Nur Muhammad Heriyanto, I Wayan Susi Dharmawan, Rozza Tri Kwatrina, Hendra Gunawan, Raden Garsetiasih, Mariana Takandjandji, Anita Rianti, Vivin Silvaliandra Sihombing, Nina Mindawati, Pratiwi, Titi Kalima, Fenky Marsandi, Marfuah Wardani, Denny, Dodo

“…<i>C. argentea</i> supplies several functions within this ecosystem that are interconnected with other components. …”
Get full text

Elucidating divergent biology in uterine carcinosarcoma by Vikas Garg, Stephenie D. Prokopec, Simone C. Stone, Sara Pakbaz, Min Li Chen, Bernard Lam, Czin Czin Benito, Michelle Mcmullen, Ilinca Lungu, Samanta Del Rossi, Anthony Msan, Valerie Bowering, Valentin Sotov, Christine Tran, Marcus O. Butler, Amit M. Oza, Phedias Diamandis, Ben X. Wang, Stephanie Lheureux

“…Both regions exhibited global hypomethylation, with functional enrichment for xenobiotic metabolism pathways in C and epithelial-to-mesenchymal transition pathways in S regions. …”
Get full text

The GRAS gene family and its roles in pineapple (Ananas comosus L.) developmental regulation and cold tolerance by Jinting Lin, Jiahao Wu, Dan Zhang, Xinkai Cai, Lumiao Du, Lin Lu, Chaojia Liu, Shengzhen Chen, Qinglong Yao, Shiyu Xie, Xiaowen Xu, Xiaomei Wang, Ruoyu Liu, Yuan Qin, Ping Zheng

“…Results In this study, 43 AcGRAS genes were identified in the pineapple genome; these genes were distributed unevenly across 19 chromosomes and 6 scaffolds and were designated as AcGRAS01 to AcGRAS43 based on their chromosomal locations. …”
Get full text

Yield, Stability, and Adaptability of Hybrid <i>Japonica</i> Rice Varieties in the East Coast of China by Rujia Chen, Gaobo Wang, Junjie Yu, Yue Lu, Tianyun Tao, Zhichao Wang, Yu Hua, Nian Li, Hanyao Wang, Ahmed Gharib, Yong Zhou, Yang Xu, Pengcheng Li, Chenwu Xu, Zefeng Yang

Get full text

Composition, Influencing Factors, and Effects on Host Nutrient Metabolism of Fungi in Gastrointestinal Tract of Monogastric Animals by Xiaofeng Deng, Hua Li, Aimin Wu, Jun He, Xiangbing Mao, Zhaolai Dai, Gang Tian, Jingyi Cai, Jiayong Tang, Yuheng Luo

“…The composition and spatial organization of mycobiota vary across different animal species and are influenced by a multitude of factors, including age, diet, and the host’s physiological state. …”
Get full text

Investigating the Effect of Microcystins on the Transcriptomics of Hepatopancreas in Penaeus vannamei Using Reverse-Gavage by Haiqing YUAN, Rongsheng JIN, Baoran WANG, Daiqiang CHEN, Shuangyong ZHANG, Zhiqiang CHANG

“…The differentially expressed genes were categorized based on biological processes, cellular components, and molecular functions using the Gene Ontology (GO) database, resulting in 33 functional entries. …”
Get full text

Glucocorticoid Receptor (GR) Expression in Human Tumors: A Tissue Microarray Study on More than 14,000 Tumors by Maria Christina Tsourlakis, Simon Kind, Sebastian Dwertmann Rico, Sören Weidemann, Katharina Möller, Ria Schlichter, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Guido Sauter, Andreas H. Marx, Ronald Simon, Ahmed Abdulwahab Bawahab, Florian Lutz, Viktor Reiswich, Davin Dum, Stefan Steurer, Eike Burandt, Till S. Clauditz, Till Krech, Christoph Fraune, Seyma Büyücek, Neele Heckmann, Natalia Gorbokon, Maximilian Lennartz, Sarah Minner, Florian Viehweger

“…<b>Conclusions</b>: GR expression is frequent across all cancer types. Associations between reduced GR expression and unfavorable tumor features in certain cancers suggest that the functional importance of GR-regulated genes in cancer progression depends on the cell of tumor origin.…”
Get full text

Flow Diversion for Intracranial Aneurysms With Incorporated Branch: A Subanalysis From the SEASE International Registry by Mahmoud Dibas, Juan Vivanco‐Suarez, Milagros Galecio‐Castillo, Demetrius Klee Lopes, Ricardo A. Hanel, Aaron Rodriguez‐Calienes, Gustavo M. Cortez, Johanna T. Fifi, Alex Devarajan, Gabor Toth, Thomas E. Patterson, David Altschul, Vitor M. Pereira, Xiao Yu Eileen Liu, Ajit S. Puri, Anna L. Kühn, Waldo R. Guerrero, Priyank Khandelwal, Ivo Bach, Peter T. Kan, Gautam Edhayan, Curtis Given, Bradley A. Gross, Sandra Narayanan, Shahram Derakhshani, Mario Martinez‐Galdamez, Santiago Ortega‐Gutierrez

“…Age, sex, comorbidities, baseline functional‐status, and IA features were similar between the 2 groups. …”
Get full text

Evaluation of the impact of ecological factors on the habitat suitability and bioactive components accumulation of the medicinal holoparasitic plant Cynomorium songaricum using mac... by Jiacheng Ji, Jiacheng Ji, Xinxin Wei, Xinxin Wei, Huan Guan, Huan Guan, Zikang Jin, Zikang Jin, Xin Yue, Zhuoran Jiang, Youla Su, Youla Su, Shuying Sun, Shuying Sun, Guilin Chen, Guilin Chen

“…BIO6 served as a key shared positive regulator for catechin and total phenolics, while functioning as a key negative regulator for ursolic acid. …”
Get full text

A GWAS of angiotensin-converting enzyme inhibitor-induced angioedema in a South African population by Jacquiline W. Mugo, PhD, Cascia Day, Cert Allergy (Phys), Ananyo Choudhury, PhD, Maria Deetlefs, Dip Allergy (SA), Robert Freercks, MPhil, Sian Geraty, MMed, Angelica Panieri, MBChB, Christian Cotchobos, MBChB, Melissa Ribeiro, MBChB, Adelein Engelbrecht, MMed, Lisa K. Micklesfield, PhD, Michèle Ramsay, PhD, Sarah Pedretti, PhD, Jonny Peter, PhD

“…Further increased sampling across the continent and matched functional work are needed to confirm the importance of genetic variation in understanding the biology of AE-ACEI.…”
Get full text

Transcriptome and Metabolome Insights into Key Genes Regulating Fat Deposition and Meat Quality in Pig Breeds by Suthar Teerath Kumar, Yunlong Zheng, Jing Xu, Ziyi Zhao, Qi Zhang, Yunpeng Zhang, Min Li, Hong Zou, Riaz Muhammad Azeem, Wu-Sheng Sun, Yuan Zhao, Shu-Min Zhang

“…Meat quality is a complex trait that exhibits significant variation across pig breeds, and the regulatory mechanisms governing pork meat quality are not fully elucidated. …”
Get full text

Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased by Christos Polysopoulos, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Almut Scherer, Daniela Di Giuseppe, Merete Lund Hetland, Michael John Nissen, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Johan Karlsson Wallman, Karel Pavelka, Jakub Závada, Ayten Yazici, Maria José Santos, Adrian Ciurea, Burkhard Möller, Brigitte Michelsen, Pawel Mielnik, Johanna Huhtakangas, Heikki Relas, Katja Perdan Pirkmajer, Ziga Rotar, Ross MacDonald, Bjorn Gudbjornsson, Irene van der Horst-Bruinsma, Marleen van de Sande, Myriam Riek

“…Methods Individual mean imputation (IMI), the modified formula method (MF), overall mean imputation (OMI), and multiple imputation of missing component values (MI) were assessed either analytically or by means of simulations from available data collected across Europe. Their performance in estimating the means of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), and the Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) in cases where component information was set missing completely at random was compared to the CC approach based on bias, variance, and coverage. …”
Get full text

A novel single-port robotic system in urology: A prospective multicenter single-arm clinical trial evaluating feasibility and efficacy of first 50 cases by Zheng Wang, Chao Zhang, Taile Jing, Yong Wei, Chengwu Xiao, Yang Wang, Yu Fang, Xiaofeng Wu, Shouyan Tang, Hong Xu, Yi Liu, Bo Yang, Shuo Wang, Bin Xu, Qingyi Zhu, Dan Xia, Zhenjie Wu, Xiaofeng Gao, Linhui Wang

“…Secondary endpoints encompassed a range of surgical metrics, functional outcomes, and patient demographic data. Clinical assessments were conducted before surgery, before discharge, and 1 month after discharge. …”
Get full text

<i>Heortia vitessoides</i> Infests <i>Aquilaria sinensis</i>: A Systematic Review of Climate Drivers, Management Strategies, and Molecular Mechanisms by Zongyu Yin, Yingying Chen, Huanrong Xue, Xiaofei Li, Baocai Li, Jiaming Liang, Yongjin Zhu, Keyu Long, Jinming Yang, Jiao Pang, Kaixiang Li, Shaoming Ye

“…Current research has preliminarily revealed its biological traits and gene functions. However, significant gaps persist in integrating climate adaptation mechanisms, control technologies, and host interaction networks across disciplines. …”
Get full text

Assessing long term impact of regional climate and human activities on vegetation greenness dynamics in Sundarbans by Muhammad Sadiq Khan, Ayesha Akter, Ismail Khan, Luis Carlos Ramos Aguila, Lina Akter, Mengmeng Yang, Xu Li, Yuelin Li

“…During the wet season, greenness expanded, showing significant correlations with precipitation (78 %) and air temperature (81 %) across most regions, except in the central Sundarbans. …”
Get full text

The Fiber Cell-Specific Overexpression of <i>COMT2</i> Modulates Secondary Cell Wall Biosynthesis in Poplar by Hanyu Chen, Hong Wang, Zhengjie Zhao, Jiarui Pan, Yao Yao, Yihan Wang, Keming Luo, Qin Song

“…Here, our report shows that <i>caffeic acid-O-methyltransferase 2</i> (<i>COMT2</i>) exhibits high conservation across several species. Tissue expression analysis reveals that <i>COMT2</i> is specifically highly expressed in the secondary xylem of <i>Populus tomentosa</i> stems. …”
Get full text

The prevalence, patterns, and antifungal drug resistance of bloodstream infection-causing fungi in Sichuan Province, China (2019–2023): a retrospective observational study using na... by Jin Deng, Jin Deng, Jin Deng, Ya Liu, Ya Liu, Ya Liu, Ling Shu, Ling Shu, Ling Shu, Dan Zhou, Dan Zhou, Dan Zhou, Yi Xie, Yi Xie, Yi Xie, Ying Ma, Ying Ma, Ying Ma, Mei Kang, Mei Kang, Mei Kang

“…Integrated clinical and laboratory data were analyzed using WHONET 5.6 to assess resistance patterns, and Microsoft Excel (with PivotTable functionality) was used to analyze epidemiological trends.ResultsAnnual fungal isolations increased steadily over the study period. …”
Get full text

A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors by Shuai Zhao, Shuai Zhao, Shuai Zhao, Lin Cheng, Xingzhao Ji, Xingzhao Ji, Shengnan Sun, Shengnan Sun, Shengnan Sun, Yi Liu, Yi Liu, Qiang Wan, Qiang Wan, Qiang Wan

“…Furthermore, we conducted cellular functional experiments to examine the effects of ZNF514 overexpression or knockdown on renal clear cell carcinoma cell proliferation, migration, and invasion.ResultsOur study found that ZNF514 expression was elevated in tumor tissues than in normal tissues in most tumor types. …”
Get full text

Methylation and gene expression patterns in adamantinomatous craniopharyngioma highlight a panel of genes associated with disease progression-free survival by Junier Marrero-Gutiérrez, Ana Carolina Bueno, Ana Carolina Bueno, Clarissa Silva Martins, Rui Milton Patrício Silva-Júnior, Antônio Carlos dos Santos, Marcelo Volpon Santos, Luiz Eduardo Wildemberg, Ximene Lima da Silva Antunes, Monica R. Gadelha, Ayrton Custodio Moreira, Ricardo Zorzetto Nicoliello Vêncio, Sonir Roberto R. Antonini, Margaret de Castro

“…Clustering analyses based on the methylation levels of probes and expression levels of the stringently filtered 212- and 37-gene sets further confirmed these two distinct ACP subgroups. Functional enrichment analysis highlighted key roles in synaptic modulation, nervous system development, cell adhesion, as well as pathways linked to RAS signaling, GTPase activity, and membrane potential regulation.ConclusionAlthough clinical characteristics were largely comparable between the clusters, ACP-B patients exhibited shorter median progression-free survival, suggesting a more aggressive phenotype. …”
Get full text