Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation by Hailing Liu, Lei Xu, Shiwei Yue, Hongfei Su, Xing Chen, Qiumeng Liu, Hui Li, Huifang Liang, Xiaoping Chen, Jiefeng He, Zeyang Ding, Bixiang Zhang

“…Notably, elevated NAT10 expression was associated with poor outcomes in HCC patients. Functionally, silencing NAT10 suppressed HCC proliferation and metastasis in vitro and in vivo. …”
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Social Relations and Interpersonal Dialogue among Couples: A Study in the City of Yazd Based on the Grounded Theory by Lida Hatefi rad, Mehraban Parsamehr, Ali Ruhani

“…It assumes distinct roles and functions and addresses a range of human needs. Central to family life and functioning are the relationships among family members. …”
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Partner-Inflicted Brain Injury: Intentional, Concurrent, and Repeated Traumatic and Hypoxic Neurologic Insults by Julianna M. Nemeth, Clarice Decker, Rachel Ramirez, Luke Montgomery, Alice Hinton, Sharefa Duhaney, Raya Smith, Allison Glasser, Abigail (Abby) Bowman, Emily Kulow, Amy Wermert

“…Survivor behavior was then interpreted by staff as a “can’t” not a “won’t”, and social and functional supports were offered.…”
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Impact of Urban Waterfront Green Space Landscape Elements on Public Health Behaviors Based on Restorative Perception by Yi WU, Hongfei QIU, Xinyue LUO, Yaping HU

“…This is coupled with MATLAB-based color quantification and assignment statistical techniques to comprehensively and meticulously quantify landscape elements across six dimensions: Space, nature, artificiality, waterfront characteristic, color and entity. …”
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Does the Ischemic Core Really Matter? An Updated Systematic Review and Meta‐Analysis of Large Core Trials After TESLA, TENSION, and LASTE by Mohammad AlMajali, Mahmoud Dibas, Malik Ghannam, Milagros Galecio‐Castillo, Abdullah Al Qudah, Farid Khasiyev, Juan Vivanco‐Suarez, Aaron Rodriguez‐Calienes, Mudassir Farooqui, Sophie L. Shogren, Fawaz AlMajali, Albert Yoo, Edgar Samaniego, Tudor Jovin, Amrou Sarraj, Santiago Ortega‐Gutierrez

“…Secondary outcomes included functional independence (mRS score 0–2), independent ambulation (mRS score 0–3), 90‐day mortality, and symptomatic intracranial hemorrhage. …”
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Uncovering genetic mechanisms associated with harmful use of alcohol in admixed Latin Americans by Edson H. B. Amaral, Gabriela de S. G. Britto, Raquel B. de São Pedro, Alberto O. Moreira, Marília O. Scliar, Ricardo Lyra, Natália P. Lima, Caroline A. Feitosa, Camila A. V. Figueiredo, Helena M. Pitangueira, Thiago Magalhães da Silva, Luydson R. S. Vasconcelos, Rodrigo F. Carmo, Maurício L. Barreto, Eduardo Tarazona-Santos, Bernardo L. Horta, Ana L. Brunialti-Godard, Pablo R. S. Oliveira

“…Association analysis was performed using multivariate logistic regression, and the functional impacts of variants were investigated through in silico analysis. …”
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Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…Their SUCRA values rank the highest, reflecting their consistent contribution to carbon sequestration across diverse settings. For instance, controlling the proportions of grasslands and pathways at 20% and 30%, respectively, and optimizing carbon storage while maintaining recreational value. …”
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Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy by Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu

“…Abstract Nanodrug delivery systems (NDDS) have demonstrated broad application prospects in disease treatment, prevention, and diagnosis due to several advantages, including functionalization capability, high drug‐loading capacity, drug stability protection, and the enhanced permeability and retention (EPR) effect. …”
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Towards a standardised monitoring of ecosystem condition: A literature review on indicators and their data sources by Isabel Nicholson Thomas, Filipe Bernardo, Constantin Cazacu, Ján Černecký, Chiara Cortinovis, Bálint Czúcz, Helena Duchkova, Martina Kičić, Sabine Lange, Xavier Lecomte, Zhi Yi Vanessa Lim, Alon Lotan, Ulla Mörtberg, Chiara Parretta, Paula Rendón, Philip Roche, Eszter Tanács, Dijana Vuletić, Christos Zoumides, Adrienne Grêt-Regamey

“…We show that the data used to develop metrics vary across ecosystem types, but remote sensing is widely used to develop spatially explicit and continuous indicators. …”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…Settings National Health Service acute hospital trusts, general practices, patients and carer homes across the north of England, United Kingdom. Participants Patients aged 75 years and older and their caregivers. …”
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Unlocking ecological insights from sub‐seasonal visible‐to‐shortwave infrared imaging spectroscopy: The SHIFT campaign by K. Dana Chadwick, Frank Davis, Kimberley R. Miner, Ryan Pavlick, Mark Reynolds, Philip A. Townsend, Philip G. Brodrick, Christiana Ade, Jean Allen, Leander Anderegg, Yoseline Angel, Indra Boving, Kristin B. Byrd, Petya Campbell, Luke Carberry, Katherine C. Cavanaugh, Kyle C. Cavanaugh, Kelly Easterday, Regina Eckert, Michelle Gierach, Kaitlin Gold, Erin Hestir, Fred Huemmrich, Maggie Klope, Raymond F Kokaly, Piper Lovegreen, Kelly Luis, Conor McMahon, Nicholas Nidzieko, Francisco Ochoa, Anna Jiselle Ongjoco, Elsa Ordway, Madeleine Pascolini‐Campbell, Natalie Queally, Dar A. Roberts, Clare M. Saiki, Fabian D. Schneider, Alexey N. Shiklomanov, Germán D. Silva, Jordan Snyder, Michele Thornton, Anna T. Trugman, Nidhi Vinod, Ting Zheng, Dulcinea M. Avouris, Brianna Baker, Latha Baskaran, Tom Bell, Megan Berg, Michael Bernas, Niklas Bohn, Renato K. Braghiere, Zach Breuer, Andrew J. Brooks, Nolan Burkard, Julia Burmistrova, Kerry Cawse‐Nicholson, John Chapman, Johana Chazaro‐Haraksin, Joel Cryer, K. C. Cushman, Kyla Dahlin, Phuong D. Dao, Athena DiBartolo, Michael Eastwood, Clayton D. Elder, Angela Giordani, Kathleen Grant, Robert O. Green, Alexa Hanson, Brendan Heberlein, Mark Helmlinger, Simon Hook, Daniel Jensen, Emma Johnson, Marie Johnson, Michael Kiper, Christopher Kibler, Jennifer Y. King, Kyle R. Kovach, Aaron Kreisberg, Daniel Lacey, Evan Lang, Christine Lee, Amanda M. Lopez, Brittany Lopez Barreto, Andrew Maguire, Elliott Marsh, Charles Miller, Dieu My T. Nguyen, Cassandra Nickles, Jonathan P. Ocón, Elijah P. Papen, Maria Park, Benjamin Poulter, Ann Raiho, Porter Reim, Timothy H. Robinson, Fernando E. Romero Galvan, Ethan Shafron, Brenen R. Skalitzky, Sydney Stroschein, Niky C. Taylor, David R. Thompson, Kate Thompson, Cecily Tye, Joelie Van Beek, Cecilia Vanden Heuvel, Jonathan Vellanoweth, Evert Vermeer, Claire Villanueva‐Weeks, Kristen Zumdahl, David Schimel

“…Abstract We stand at the threshold of a transformative era in Earth observation, marked by space‐borne visible‐to‐shortwave infrared (VSWIR) imaging spectrometers that promise consistent global observations of ecosystem function, phenology, and inter‐ and intra‐annual change. …”
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HiBC: a publicly available collection of bacterial strains isolated from the human gut by Thomas C. A. Hitch, Johannes M. Masson, Charlie Pauvert, Johanna Bosch, Selina Nüchtern, Nicole S. Treichel, Marko Baloh, Soheila Razavi, Afrizal Afrizal, Ntana Kousetzi, Andrea M. Aguirre, David Wylensek, Amy C. Coates, Susan A. V. Jennings, Atscharah Panyot, Alina Viehof, Matthias A. Schmitz, Maximilian Stuhrmann, Evelyn C. Deis, Kevin Bisdorf, Maria D. Chiotelli, Artur Lissin, Isabel Schober, Julius Witte, Thorsten Cramer, Thomas Riedel, Marie Wende, Katrin A. Winter, Lena Amend, Alessandra Riva, Stefanie Trinh, Laura Mitchell, Jonathan Hartman, David Berry, Jochen Seitz, Lukas C. Bossert, Marianne Grognot, Thorsten Allers, Till Strowig, Michael Pester, Birte Abt, Lorenz C. Reimer, Jörg Overmann, Thomas Clavel

“…This collection of easily searchable and publicly available gut bacterial isolates will facilitate functional studies of the gut microbiome.…”
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全球教師社群研究之趨勢分析 Analysis of Trends in Global Teacher Community Research by 謝傳崇 Chuan-Chung Hsieh, 宋雨柔 Yurou Song, 沈芷嫣 Jr-Yan Shen, 江宛霖 Wan-Lin Chiang, 古耘睿 Yun-Ruei Ku

“…The conceptualization of teacher communities varies across international contexts. For instance, Hord (2004) emphasizes “professional learning communities,” while Dufour (2004) argues that student learning should be the core focus. …”
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Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure by Yuqing Zhang, Shourui Hu, Shan Han, Congcong Liu, Xiaofan Liang, Yuxuan Li, Zongxuan Lin, Yiming Qin, Chunxuan Geng, Yue Liu, Linlin Cui, Jingmei Hu, Changming Zhang, Zhao Wang, Xin Liu, Jinlong Ma, Zi-Jiang Chen, Han Zhao

“…Male offspring mice with prenatal AE exhibited hyperglycemia and glucose intolerance across three generations, which were further exacerbated by aging and a high-fat diet. …”
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Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia by Sungmi Jeon, Seol-Ha Jeong, Mi Hyun Lee, Jeong Wook Seo, Da-Seul Kim, Nicole Joy Bassous, Javier Alejandro Lozano Soto, Cholong Choi, Montserrat Legorreta Gonzalez, Elaine Belén Nolasco Díaz, Hyunho Kim, Su Ryon Shin, Ji-Ung Park

“…Using a large 3 × 9 cm2 rat random-pattern skin flap model, flap survival and regeneration were evaluated across four groups: control, pure GelMA hydrogel, and cOMP-GelMA hydrogel with two concentrations of cOMPs (0.2 % and 0.5 % w/v). …”
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Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma by Kenji Mizumura, Yasuhiro Gon, Norihiro Harada, Shiho Yamada, Asami Fukuda, Ryosuke Ozoe, Shuichiro Maruoka, Sumiko Abe, Kazuhisa Takahashi, Akihiko Tanaka, Hironori Sagara, Taisuke Akamatsu, Toshihiro Shirai, Katsunori Masaki, Koichi Fukunaga, Konomi Kobayashi, Hiroyuki Nagase, Nobuaki Miyahara, Arihiko Kanehiro, Noboru Kitamura, Naruhiko Sugihara, Fumio Kumasawa, Junko Terada-Hirashima, Masayuki Hojo, Kazuyuki Chibana, Etsuko Tagaya

“…Background: The therapeutic effectiveness of dupilumab for severe asthma in real-world settings is yet to be prospectively investigated across multiple institutions, and uncertainties persist regarding predictive factors for its effectiveness. …”
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Resolving Turbulence Drivers in Two Luminous Obscured Quasars with JWST/NIRSpec Integral Field Unit by Mandy C. Chen, Hsiao-Wen Chen, Michael Rauch, Andrey Vayner, Weizhe Liu, David S. N. Rupke, Jenny E. Greene, Nadia L. Zakamska, Dominika Wylezalek, Guilin Liu, Sylvain Veilleux, Nicole P. H. Nesvadba, Caroline Bertemes

“…Utilizing high-resolution data from the NIRSpec integral field unit onboard the James Webb Space Telescope, we analyze the velocity fields of line-emitting gas in and around these quasars and construct the second-order velocity structure functions (VSFs) to quantify turbulent motions across different spatial scales. …”
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Seasonal Influenza Vaccination Programs in the Americas: A Platform for Sustainable Life-Course Immunization and Its Role for Pandemic Preparedness and Response by Francisco Nogareda, Margherita Ghiselli, Martha Velandia-González, Bremen de Mucio, Jorge Jara, Paula Couto, Angel Rodriguez, Marc Rondy, Andrea Vicari, Murat Hakan Ozturk, Shoshanna Goldin, Alba Vilajeliu, Eva Leidman, Jaymin Patel, Julie Carlton, Ashley L. Fowlkes, Eduardo Azziz-Baumgartner, Daniel Salas Peraza, Alba Maria Ropero

“…<b>Methods:</b> In this review, we present the history and progress of the seasonal influenza program in the Americas, how the program contributed to the efficient and timely roll-out of the COVID-19 vaccines during the pandemic, and how the program can be used to promote immunization operations across the life span for existing and future vaccines. …”
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Essential Equipment for Baseline Otolaryngology‐Head and Neck Surgery Care: A Global Cross‐Sectional Survey by Tarika Srinivasan, Alexander Cherches, Amina Seguya, Akansha Pandey, David Fei‐Zhang, Sarah Nuss, Zachary Elwell, Adebolajo Adeyemo, Blake C. Alkire, Ali Haider Bangash, Gabrielle Cahill, Davina Daudu, Carolina Der Mussa, Taseer Din, Johannes J. Fagan, Racheal Hapunda, Titus Ibekwe, Ivy Maina, Allan Mukuzi, Rolvix H. Patterson, David A. Shaye, Emily R. Smith, Holly Sprow, Christopher James Waterworth, Joshua P. Wiedermann, Mary Jue Xu, Nader Zalaquett, Aveline Aloyce Kahinga, Sharon Ovnat Tamir, Global OHNS Initiative

“…Differences existed among commonly used equipment such as tympanomastoidectomy equipment and rigid bronchoscopy, to subspecialized equipment such as functional endoscopic sinus surgery equipment and cochlear implants (p < 0.05 each). …”
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Genetic association of the kynurenine pathway to suicidal behavior by Rabah Tamimou, Christine Montout, Thibault Mura, Ismael Conejero, Alexandre Evrard, Philippe Courtet, Pablo Bonilla-Escribano, Carlos Riaza, Concepción Vaquero-Lorenzo, Enrique Baca-Garcia, Fabrice Jollant, Serge Lumbroso, Kevin Mouzat, Jorge Lopez-Castroman

“…To validate our findings, it is crucial to conduct functional analyses to investigate the impact of rs10109853 and rs1053230 SNPs on the expression and/or catalytic activity of the corresponding enzymes.…”
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