Overview of Effects of Motor Learning Strategies in Neurologic and Geriatric Populations: A Systematic Mapping Review by Li-Juan Jie, PhD, Melanie Kleynen, PhD, Guus Rothuizen, MSc, Elmar Kal, PhD, Andreas Rothgangel, PhD, Susy Braun, PhD

“…Objective: To provide a broad overview of the current state of research regarding the effects of 7 commonly used motor learning strategies to improve functional tasks within older neurologic and geriatric populations. …”
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Integrative analysis based on ATAC-seq and RNA-seq reveals a novel oncogene PRPF3 in hepatocellular carcinoma by Yi Bai, Xiyue Deng, Dapeng Chen, Shuangqing Han, Zijie Lin, Zhongmin Li, Wen Tong, Jinming Li, Tianze Wang, Xiangyu Liu, Zirong Liu, Zilin Cui, Yamin Zhang

“…Abstract Background Assay of Transposase Accessible Chromatin Sequencing (ATAC-seq) is a high-throughput sequencing technique that detects open chromatin regions across the genome. These regions are critical in facilitating transcription factor binding and subsequent gene expression. …”
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Succession characteristics and assembly process of soil microbiome at reclaimed farmlands in coal mining area by Jianhua Li, Jianhua Li, Zixu Li, Yanwen Sun, Jinjing Lu, Jinjing Lu, Qiang Zhang, Xinhua He, Xinhua He, Xinhua He, Minggang Xu, Minggang Xu

“…Clarifying the succession patterns and assembly mechanisms of soil bacterial and fungal communities across reclamation chronosequences is essential for restoring soil health and ensuring ecological stability in mining areas. …”
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Performance Study of Non-Contact Membrane Distillation Engineering Prototype for Treatment of Radioactive Wastewater by Bao-lin WANG, De-tao XIAO, Zheng-zhong HE, Xing-feng YANG, Cheng-lin LI

“…This adjustable treatment capacity allows operators to calibrate the processing rate in real time, aligning the system’s functionality with varying demands and expanding its applicability across diverse use cases. …”
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Characterization of Turkish mulberry genetic resources based on antioxidant capacity, biochemical composition, nutrient content, and morphological traits of leaves by Yazgan Tunç, Ali Khadivi, Mehmet Yaman, Kadir Uğurtan Yılmaz, Ercan Yıldız, Adem Güneş, Yusuf Murat Keçe, Duygu Özelçi, Daya Shankar Mishra

“…These genotypes, representing Morus alba, M. nigra, M. rubra, and unidentified species, were cultivated to evaluate their genetic diversity and potential for functional applications. The genotype ‘Gosho Erami’ exhibited the highest performance across total antioxidant activity (87%), phenolic contents (40.58 mg GAE/100 g), and flavonoid contents (6.48 mg QE/100 g), while ‘Hatay Dörtyol Mordut’ had the lowest values (50.61%, 20.33 mg GAE/100 g, and 2.11 mg QE/100 g, respectively). …”
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Sagittal Plane Kinematic Deviations and Spatio-Temporal Gait Characteristics in Children with Idiopathic Toe Walking: A Comparative Analysis Using Statistical Parametric Mapping by Rocio Pozuelo-Calvo, Almudena Serrano-Garcia, Yolanda Archilla-Bonilla, Angel Ruiz-Zafra, Manuel Noguera-Garcia, Kawtar Benghazi-Akhlaki, Miguel Membrilla-Mesa, Carla DiCaudo, Jose Heredia-Jimenez

“…Future research should explore the long-term musculoskeletal consequences of these deviations and optimize therapeutic strategies, such as physical therapy and orthotic interventions, to improve gait functionality and quality of life.…”
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Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma by Denggang Fu, Biyu Zhang, Wenyan Fan, Fanfan Zeng, Fanfan Zeng, Jueping Feng, Xin Wang

“…ROC analysis confirmed the signature’s validity across validation sets. TIME analysis revealed higher infiltration of CD8+ T cells, natural killers, and B cells, and lower tumor purity, stemness index, and tumor mutation burden (TMB) in low-risk patients. …”
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Targeting CD276 with Adapter-CAR T-cells provides a novel therapeutic strategy in small cell lung cancer and prevents CD276-dependent fratricide by Beate Kristmann, Niels Werchau, Lakshmi Suresh, Elisabeth L. Pezzuto, Sophia Scheuermann, Simon Krost, Karin Schilbach, Moustafa Moustafa-Oglou, Anna-Sophia Mast, Miriam Droste, André Felsberger, Lukas Kiefer, Pierre Abramowski, Lars Zender, Joerg Mittelstaet, Christian M. Seitz

“…Results CD276 is broadly expressed across SCLC subtypes, representing a promising target for CAR-T therapy. …”
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Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury by Katerina Stepankova, Barbora Smejkalova, Lucia Machova Urdzikova, Katerina Haveliková, Fred de Winter, Stepanka Suchankova, Joost Verhaagen, Vit Herynek, Rostislav Turecek, Jessica Kwok, James Fawcett, Pavla Jendelova

“…In animals treated with α9 integrin and kindlin-1, sensory axons regenerated through tenascin-C-expressing connective tissue strands and bridges across the lesions and then re-entered the CNS tissue. …”
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Microbial life-history strategies and genomic traits between pristine and cropland soils by Dan He, Zhongmin Dai, Shuxun Cheng, Haojie Shen, Jiahui Lin, Kankan Zhao, Jorge L. Mazza Rodrigues, Yakov Kuzyakov, Jianming Xu

“…ABSTRACT Microbial life-history strategies [inferred from ribosomal RNA operon (rrn) gene copy numbers] and associated genomic traits and metabolism potentials in soil significantly influence ecosystem properties and functions globally. Yet, the differences in microbial strategies and traits between disturbed (cropland) and pristine soils, along with their dominant driving factors, remain underexplored. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…Following intravenous administration, MRI and MPI functionalities were analyzed through phantom studies and in vivo murine models.Results: Coated M55 NPs displayed high colloidal stability in water and effective functionalization. …”
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Genome-wide identification, characterization, and expression analysis of the MADS-box gene family in grass pea (Lathyrus sativus) under salt stress conditions by Mohamed Abdelsattar, Ahmed E. Nassar, Khaled H. Mousa, Ahmed Hussein, Manal M. S. El-Baghdady, Khaled H. Radwan, Manar S. Ibrahim, Achraf El Allali, Aladdin Hamwieh, Alsamman M. Alsamman, Zakaria Kehel

“…The grass pea (Lathyrus sativus), a crop grown predominantly in arid and semi-arid regions, could benefit greatly from the functions of MADS-box genes, which are not yet well characterized in this promising plant. …”
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Genetic predisposition to immune dysregulation and extracellular matrix remodeling in cardiac arrhythmia reveals potential mediation by SPP1+ macrophages by Jie-Yuan Jin, Jie-Yuan Jin, Shuai Guo, Yao Deng, Ya-Qin Chen, Chen Liang, Yu-Jie Jiang, Wang Zhao, Rong Xiang

“…Single-cell analysis of 37,675 cells revealed conserved transcriptional signatures across cell types, characterized by enhanced cytokine responses and pro-fibrogenic programs. …”
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Redefining boundaries: unveiling the schism in teacher-parent perceptions of educational engagement by Yael Fisher, Shiran Baissberg

“…This approach allowed for a comprehensive examination of parents' and teachers' perspectives across various educational levels.ResultsThe findings of this study indicate that parents' and teachers' perceptions of parental involvement differ fundamentally. …”
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Agroclimatic and agroecotoxicological justification of zonal chemical protection systems against harmful organisms for field crops under conditions of climate change in Ukraine by O. Borzykh, L. Bublyk, V. Chaika, L. Gavrylyuk, I. Kruk, O. Shevchuk, T. Neverovska, O. Bakhmut

“…This led to a disruption in the functioning of agrocenoses, a decrease in tolerance to the pesticide load. …”
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White matter microstructure links with brain, bodily and genetic attributes in adolescence, mid- and late life by Max Korbmacher, Mario Tranfa, Giuseppe Pontillo, Dennis van der Meer, Meng-Yun Wang, Ole A. Andreassen, Lars T. Westlye, Ivan I. Maximov

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Harnessing the angiogenic potential of adipose-derived stromal vascular fraction cells with perfusion cell seeding by Gregory Reid, Giulia Cerino, Ludovic Melly, Deborah Fusco, Chunyan Zhang, Oliver Reuthebuch, Giulia Milan, Anna Marsano

“…Abstract Background The rapid formation and long-term maintenance of functional vascular networks are crucial for the success of regenerative therapies. …”
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Molecular cloning of PRD-like homeobox genes expressed in bovine oocytes and early IVF embryos by Barış Yaşar, Nina Boskovic, Marilin Ivask, Jere Weltner, Eeva-Mari Jouhilahti, Piibe Vill, Tiina Skoog, Ülle Jaakma, Juha Kere, Thomas R. Bürglin, Shintaro Katayama, Tõnis Org, Ants Kurg

“…Additionally, our cDNA cloning approach allowed us to reveal breed-related differences in bovine, as evidenced by the identification of a high number of single nucleotide variants (SNVs) across the PRDL class homeobox genes. Subsequently, we observed the prediction of the 9aa transactivation domain (9aaTAD) motif in the putative protein sequence of TPRX3 leading us to conduct functional analysis of this gene. …”
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Stimuli-responsive antimicrobial polymer systems: From structural design to biomedical applications by Jia Guo, Yaqi Tao, Zhen Du, Siqi Zhang, Wei Zheng, Zhibo Wang, Zhuomin Yi, Yangqing Gou, Wen Tang

“…Among various materials, polymer-based stimuli-responsive systems stand out thanks to their structural design flexibility, functional diversity, decreased systemic toxicity, and enhanced therapeutic effects compared with free drugs. …”
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Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling by Yanan Peng, Xinhua Duan, Linfan Zhang, Yiyi Guo, Jinlin Cao, Weiping Ao, Rong Xuan

“…Experimental validation showed that chi-miR-423-3p inhibited mammary epithelial cell proliferation, induced G1/S cell cycle arrest, and promoted apoptosis by targeting IGF1R and suppressing the PI3K/Akt pathway.ConclusionThis study highlights the dynamic regulatory roles of miRNAs in the goat mammary gland across lactation stages. Notably, the miR-423-3p/IGF1R axis is a key regulator of mammary remodeling during the dry period, offering new insights into the molecular basis of mammary gland functional transitions.…”
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