In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug D... by Obinna C. Ubah, Andrew J. Porter, Caroline J. Barelle

“…The serum levels of the Quad-X™ and D1-NDure™-C4 modalities were consistently high and comparable across all mice within the same treatment groups. …”
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Preparation and Applications of Biochar Materials from Organic Solid Waste by Yufei TANG, Jiacheng SONG, Yuhang GUO, Jialu QU, Jian XIONG, Yina QIAO, Xuebin LYU

“…Despite its promising applications across multiple fields, research on the long-term environmental impacts and potential risks of biochar remains relatively limited. …”
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The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism by Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng

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Psychometric properties of the Chinese version of scales of knowledge, attitude, and practice of self-care for patients with arteriovenous fistula: a translation and verification s... by Chuang Li, Chuang Li, Youbei Lin, Jiaxin Cheng, Danfeng Xu, Danfeng Xu, Lan Zhang

“…However, future studies should consider expanding the sample size and evaluating the scale’s longitudinal stability and applicability across different cultural contexts.…”
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Unmet long-term care needs and their association with health-related quality of life among Chinese oldest-old population by Jiajun Qiao, Yiwei Qiao, Jialong Tan, Nuo Chen, Nan Peng, Zongfu Mao, Yali Zhao, Chen Chen, Yao Yao

“…Abstract Background Entering the age of 80 or 100, individuals’ functional decline and the need for assistance in daily activities increase dramatically, resulting in an inevitable increase in unmet long-term care (LTC) needs. …”
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Evaluation of the effect of DRG payment policy based on interrupted time series modeling: evidence from a tertiary hospital in Anhui Province by Guangju Mo, Erchang Zhu, Xinlei Fang, Jingbo Ma, Sijing Kong, Xuan Guo, Zheng Lu

“…Future research should focus on the long-term effects of the DRG policy across different healthcare institutions.…”
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Exploring the influence of sex and age on the quality and flavor of Huai goat longissimus thoracis et lumborum through transcriptomic and metabolomic analyses by Haoyuan Han, Ziru Kuai, Zhiyun Yao, Xi Lei, Huibin Shi, Jun Li, Kun Liu, Huiru Yin, Yongqing Wang, Kai Quan

“…RNA sequencing (RNA-Seq) was conducted to identify differentially expressed genes (DEGs) across different ages and sexes. Metabolite profiling was performed by liquid chromatography‒mass spectrometry (LC‒MS) to detect and quantify metabolites. …”
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Comprehensive Analysis of the Role of Heat Shock Proteins in the Immune Microenvironment and Clinical Significance of Hepatocellular Carcinoma by Xiao H, Wang B, Xiong S, Li C, Ding Y, Chao D, Mei B, Shen N, Luo G

“…However, the specific role of HSPs in HCC requires further investigation.Methods: We analyzed the genomic characteristics of HSPs in liver cancer in the TCGA and ICGC databases, and functional enriched analysis of HSPs. Construction of an HSPs-Related Prognostic Model for patients with hepatocellular carcinoma. …”
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Time to Radiographic Union Following Minimally Invasive META Procedure for Hallux Valgus by Taylor Schnepp MS, Kyle Lorenzo BS, Chase Burzynski BS, Jason Mirharooni BS, Wade Massey MD, Thomas San Giovanni MD, Christopher W. Hodgkins MD, Cary B. Chapman MD

“…No significant differences in time to union were observed across metatarsal shift groups. Complications include 3 nonunions, 3 revisions, 16 cases that necessitated removal of hardware, 1 case of superficial wound infection, 1 case of deep wound infection, and 6 deformity recurrences. …”
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Effectiveness and Safety of Acupuncture as an Adjunctive Therapy for Post-Stroke Depression: An Overview of Systematic Reviews by Liu X, Zhu F, Zhang JL, He ZX, Yin S, Wu RH, He YY, Zeng F

“…Acupuncture as an adjuvant therapy shows promise, though current systematic reviews exhibit significant discrepancies in effectiveness/safety evidence with insufficient methodological rigor.Purpose: To evaluate systematic reviews assessing acupuncture as an adjuvant therapy for PSD.Methods: Electronic searches were conducted across eight databases from their inception to March 2024. …”
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Use of Technology to Support Health Care Providers Delivering Care in Low- and Lower-Middle-Income Countries: Systematic Umbrella Review by Adam Craig, Harriet Lawford, Maggie Miller, Liuyi Chen-Cao, Leanna Woods, Siaw-Teng Liaw, Myron Anthony Godinho

“…Data extracted were deductively coded and thematically analyzed according to the 11 health system functions outlined in the 2023 World Health Organization classification of DHIs. …”
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An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced bi... by Shaker Hassan S. Alshehri, Mastour Saeed Alshahrani, Saeed Y. Al Adal, Faisal M. Alyazedi, Hani Hassan Alnakhli, Ravi Shankar Reddy

“…AJPS was assessed using a digital inclinometer across four movement directions (plantarflexion, dorsiflexion, inversion, eversion). …”
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Multiscale analysis of global variation in tree allometric relationships: parameter sets for global vegetation models by Ian Grant, Wenge Ni-Meister, Nancy Y Kiang

“…We found that the degree of within-biome variation across continents depends on biome, with tropical rain forests exhibiting much less variation than temperate broadleaf forests. …”
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Factors Influencing Telemedicine Adoption Among Health Care Professionals: Qualitative Interview Study by Fiona Schürmann, Daniel Westmattelmann, Gerhard Schewe

“…Transparency emerged as a critical antecedent of trust across different referents, comprising disclosure, clarity, and accuracy. …”
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<i>Celosia argentea</i>: Towards a Sustainable Betalain Source—A Critical Review and Future Prospects by Preekamol Klanrit, Sudarat Thanonkeo, Poramaporn Klanrit, Poramate Klanrit, Kanchanok Mueangnak, Pornthap Thanonkeo

“…This diverse bioactivity underpins their value across various industries. Betalains serve as natural colorants and functional ingredients in food and beverages, offer sustainable alternatives for textile dyeing, and hold therapeutic promise in cosmetics and pharmaceuticals. …”
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Insights into carbon and nitrogen footprints of large-scale intensive pig production with different feedstuffs in China by Huijun Wu, Yongxin Liu, Ling Zhang, Huimin Zhu, Weixin Fang, Wei Mei

“…Concerning the uneven feed crop production, number of pig farrowed, feed consumption, and inter-provincial transportation across China, we conducted the spatial analysis under the optimal S3. …”
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Assessing the Predictive Accuracy of Popular Comorbidity Indices in Total Ankle Arthroplasty Outcomes by Weston E. McDonald BS, Alexander S. Guareshi BS, Joshua L. Morningstar BS, Daniel J. Scott MBA, MD, Christopher E. Gross MD

“…Two potential tools, the Charlson Comorbidity Index (CCI) and Elixhauser Comorbidity Index (ECI), have been widely supported and utilized across various fields of medicine and orthopaedic surgery. …”
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Effects of intercropping with legume forage on the rhizosphere microbial community structure of tea plants by Yuhang Jiang, Yuhang Jiang, Yuhang Jiang, Xiaoqin Lin, Wenxiong Lin, Wenxiong Lin

“…This rhizospheric enhancement has significantly potentiated the ecological functionalities within the bacterial community, including xylanolysis, ureolysis, nitrogen respiration, nitrogen fixation, nitrite respiration, nitrite ammonification, and nitrate reduction. …”
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Validation of the de Morton Mobility Index for measuring mobility related activities in Hungarian institutionalized older adults by Zsigmond Gyombolai, Alexandra Zimonyi-Bakó, Anna Zsófia Kubik, Brigitta Arndt, Izabella Jónásné Sztruhár, Richárdné Mayer, András Simon, Gyöngyvér Molnár, Éva Kovács

“…Significant differences in the DEMMI score were found across groups being at various levels of assistive device use. …”
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Genome-wide identification and expression pattern analysis of NAC family in Taxus yunnanensis and the TyuNAC30 role in paclitaxel production by Jiangtao Fan, Yong Wang, Mengke Dou, Qiuhong Hu, Qing Li, Shengmei Gan, Mingwei Jing, Gang Wang, Xiong Huang

“…Yeast one-hybrid and related assays revealed that TyuNAC30 functions as a negative regulator of TyuDBTNBT, a key enzyme gene in the paclitaxel biosynthetic pathway. …”
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