Editorial by Teddy Surya Gunawan

“…We hope this collection will inspire further research, inform policy and industrial practices, and foster collaborations across academia and industry to pursue sustainable and inclusive technological development.. …”
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Early Digital Engagement Among Younger Children and the Transformation of Parenting in the Digital Age From an mHealth Perspective: Scoping Review by Nafisa Anjum, Md Mehedi Hasan, Nursat Jahan, Sheikh Iqbal Ahamed, Allison Garefino, Nazmus Sakib

“…This study provides valuable insights into improving obedience to healthy screen use and fostering a digital ecosystem where technology itself functions as an advocate of child progress, instead of an obligation.…”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

“…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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Lipopolysaccharide-binding protein (LBP): a prognostic biomarker for gastric cancer linked to immune infiltration by Hao Lv, Mei Lv, Xuyang Guo, Xiaoman Zhu, Yue Chao, Dandan Li

“…Results Our pan-cancer comparative analysis across 33 cancer types revealed significant upregulation of LBP in gastric cancer, with diagnostic ROC curve analysis yielding an AUC of 0.765. …”
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Identification of QTLs for early maturity-related traits based on RIL population of two elite cotton cultivars by Xiaoge Wang, Fanjin Kong, Liying Gao, Guifang Shen, Bing Duan, Zongwen Wang, Dongdong Xu, Degang Fan, Yongsheng Deng, Zongfu Han

“…Results In this study, ‘SCRC19’ and ‘SCRC21’, two excellent cultivars with significantly different WGP, along with their recombinant inbred lines (RILs) consisting of 150 individuals were re-sequenced, yielding 4,092,677 high-quality single nucleotide polymorphisms (SNPs) and 794 bin markers across 26 chromosomes. A genetic map spanning 2213.71 cM was constructed using the 794 bin markers. …”
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Effects of foliar selenium spraying on the growth and selenium content and morphology of rice by Wenxia Pei, Mengya Dai, Sheng Shi, Yuan Zhang, Daxia Wu, Cece Qiao, Yafei Sun, Jianfei Wang

“…Selenium (Se), an essential micronutrient for both plants and humans, plays critical roles in crop metabolism and human physiological functions. However, optimizing Se biofortification strategies to enhance grain Se accumulation while mitigating potential agronomic trade-offs remains a significant challenge. …”
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Avoidant/Restrictive Food Intake Disorder in Adult Patients with Gastrointestinal Diseases: A Concept Analysis Using Evolutionary Approach by Che Y, Li S, Hu X, Hu H, Zhang C, He C

“…The confusion and unclear definitions of related concepts have hindered further research and exploration.Objective: This study aims to clarify the concept of avoidant/restrictive food intake disorder in adults with gastrointestinal diseases and to enhance clinicians’ awareness of this phenomenon.Design: Rodgers’ evolutionary concept analysis.Methods: A systematic literature search targeting avoidant/restrictive food intake disorder in adult patients with gastrointestinal diseases was conducted using keywords and entry terms across seven databases, including PubMed, Web of Science, EBSCO, CINAHL, PsycINFO, EMBASE, and CNKI (up to September 28, 2024). …”
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The association between frailty index and abdominal aortic calcification in the middle-aged and older US adults: NHANES 2013–2014 by ZhengJun Zhang, Peng Wu, Shaobin Yang, Baozhen Zhu, Dapeng Chen, Xiaocheng Li, Yarong Wang, Ning Yan

“…Subgroup analyses and interaction tests were conducted to assess the stability of this association across different populations.ResultsA total of 2,572 participants were enrolled in this study. …”
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CoNfasTT: A Configurable, Scalable, and Fast Dual Mode Logic-Based NTT Design by Eldar Cohen, Leonid Yavits, Benjamin M. Zaidel, Alexander Fish, Itamar Levi

“…The widespread adoption of NTT and similar repeated structures across various fields underscores the broad applicability of our findings. …”
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App-based daily self-measurement of impedance in cochlear implant users by Sarah Vormelcher, Sarah Vormelcher, Cornelia Batsoulis, Daniel Kley, Michael Mair, Andreas Büchner

“…IntroductionImpedance telemetry measurements in cochlear implant (CI) recipients are commonly used to assess CI electrode functionality and provide valuable insights into inner ear conditions. …”
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Micro-scale genetic structure and genetic variation of Neotricula aperta (Gastropoda: Pomatiopsidae), the intermediate host of Schistosoma mekongi (Digenea: Schistosomatidae) in Ch... by Naruemon Bunchom, Weerachai Saijuntha, Chairat Tantrawatpan, Wanchai Maleewong, Joseph Valencia, Takeshi Agatsuma, Virasack Bounavong, Philippe Buchy, Moritoshi Iwagami

“…Methods A total of 80 N. aperta snails were collected from 13 various localities across five villages in Khong and Mounlapamok districts in Champasak Province, Laos in May 2024. …”
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Frontal Transcranial Direct Current Stimulation in Moderate to Severe Depression: Clinical and Neurophysiological Findings from a Pilot Study by Florin Zamfirache, Gabriela Prundaru, Cristina Dumitru, Beatrice Mihaela Radu

“…<b>Results</b>: Following tDCS treatment, significant reductions in MADRS scores were observed across the cohort, with clinical response rates notably higher in the moderate/severe group (71.4%) compared to the mild depression group (20.0%). …”
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Psychosocial challenges among Asian adolescents and young adults with cancer: a scoping review by Yihui Wei, Panpan Xiao, Weishang Deng, Cho Lee Wong, Chun-Kit Ngan, Winnie Wan-Yee Tso, Alex Wing-Kwan Leung, Herbert Ho-Fung Loong, Chi Kong Li, Alexandre Chan, Yin Ting Cheung

“…Given the variability in economic development and healthcare infrastructure across Asia, region-specific healthcare policies and services are required for AYA survivors.…”
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AQP5 trafficking is regulated by its C-terminal tail and interaction with prolactin-inducible protein by Claudia D’Agostino, Egor Zindy, Louise Conrard, Amel Takkal, Françoise Gregoire, Nargis Bolaky, Susanna Törnroth-Horsefield, Jason Perret, Christine Delporte

“…Abstract Background Aquaporin-5 (AQP5) is a crucial membrane protein involved in water transport across cellular membranes, particularly within exocrine glands such as salivary glands. …”
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The Causal Association Analysis between Depression and Cerebrospinal Fluid: From the Perspective of Mendelian Randomization by Zhang Y, Wu P, Liu Z

“…Yu Zhang,1,2,&amp;ast; Ping Wu,3,&amp;ast; Zhuo Liu1,4 1Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine (The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine), Changsha, Hunan, 410006, People’s Republic of China; 2Integrated Traditional Chinese and Western Medicine College of Hunan University of Chinese Medicine, Changsha, Hunan, 410208, People’s Republic of China; 3Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde, Hunan, 415099, People’s Republic of China; 4College of Traditional Chinese Medicine, Changsha Medical University, Changsha, Hunan, 410219, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Zhuo Liu, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine (The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine, No. 58 Lushan Road, Yuelu District, Changsha City, Hunan Province, 412000, People’s Republic of China, Email 330811844@qq.comBackground: Major depressive disorder (MDD) leads to significant distress and disruption across social, occupational, and other functional domains. …”
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The Effectiveness of Therapeutic Exercise Interventions With Virtual Reality on Balance and Walking Among Persons With Chronic Stroke: Systematic Review, Meta-Analysis, and Meta-Re... by Maria Krohn, Aki Rintala, Jaakko Immonen, Tuulikki Sjögren

“…MethodsStudies were searched across 6 databases. The inclusion criteria were as follows: Adults aged 18 years or older with a stroke diagnosis for at least 6 months (population). …”
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Attenuation of salinity-induced stress and improvement of brackish water aquaculture of Labeo rohita through dietary interventions of multi-species probiotics by Habiba Jamil, Abdul Ghaffar, Fozia Afzal, Hussain Ahmad, Ghulam Abbas, Dalia Fouad, Farid Shokry Ataya, Kun Li

“…Studies of erythrocytes structures and intestinal histometric indices revealed significant improvement across MSP feeding in salinity test groups, compared to non-probiotic salinity groups (p < 0.05). …”
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Quantitative proteomic data of flotillin-2 interactome within detergent resistant membranes of HeLa cells by Anita Hryniewicz-Jankowska, Michał Tracz, Ilona Opiełka, Katarzyna Augoff, Aleksander Czogalla, Aleksander F. Sikorski

“…The two analyses allowed for relative quantification of ∼433 and ∼926 unique proteins across the N-terminal and C-terminal BirA* fusions, respectively. 28 (N-terminal) and 88 (C-terminal) proteins were observed as significantly enriched in flotillin-2 samples (28 and 43 with fold change ≥ 2). …”
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The Helicobacter pylori orphan ATTAAT-specific methyltransferase M.Hpy99XIX plays a central role in the coordinated regulation of genes involved in iron metabolism by Wilhelm Gottschall, Florent Ailloud, Christine Josenhans, Sebastian Suerbaum

“…Methylation has been associated with multiple functions in H. pylori, including the defense against foreign DNA and transcriptional regulation. …”
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C→U transition biases in SARS-CoV-2: still rampant 4 years from the start of the COVID-19 pandemic by Peter Simmonds

“…In contrast to an approximately random distribution of other transitions across the genome, most C→U substitutions occurred at statistically preferred sites in each lineage. …”
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