Efficacy of deep brain stimulation for Tourette syndrome and its comorbidities: A meta-analysis by Anyi Zhang, Tinghong Liu, Jinshan Xu, Qing Zhao, Xianbin Wang, Zhongliang Jiang, Shuli Liang, Yonghua Cui, Ying Li

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Comprehensive characterization of poplar HSP20 gene family: genome-wide identification, stress-induced expression profiling, and protein interaction verifications by Lincui Shi, Yude Kang, Ling Ding, Liejia Xu, Xiaojiao Liu, Anmin Yu, Aizhong Liu, Ping Li

“…Furthermore, Yeast Two-Hybrid (Y2H) assays demonstrated potential regulatory interactions between PyHSP20s and other functional proteins involved in stress responses. Conclusions These findings provide a comprehensive understanding of the classification, structural differentiation, and functional roles of PyHSP20s in P. yunnanensis, thereby establishing a foundation for future functional investigations into this protein family.…”
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Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…Abstract Background The Sec14 domain is an ancient lipid-binding domain that evolved from yeast Sec14p and performs complex lipid-mediated regulatory functions in subcellular organelles and intracellular traffic. …”
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Esophageal cancer and precancerous lesions: focus on resident bacteria and fungi by Liping Yuan, Yi Zhang, Chengli Wen, Sha Liu, Qin Zhang, Wen Yin, Qian Jia, Maolin Chen, Gang Luo, Mingming Deng, Muhan Lv, Wanmeng Xiao

“…These findings delineate microbiome alterations across ESCC stages, emphasizing ESIN-specific microbial shifts that may inform microbiome-based strategies for early detection and intervention.IMPORTANCEThis study collected esophageal tissues through gastroscopic biopsy and conducted sequencing and analyses to explore the diversity, heterogeneity, key microbial composition, interaction networks, and functional predictions of resident bacteria and fungi in esophageal squamous cell carcinoma (ESCC) progression. …”
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Advancements in bioengineered and autologous skin grafting techniques for skin reconstruction: a comprehensive review by Jillian Dean, Cosima Hoch, Barbara Wollenberg, Justin Navidzadeh, Bhagvat Maheta, Anisha Mandava, Samuel Knoedler, Khalil Sherwani, Helena Baecher, Alina Schmitz, Michael Alfertshofer, Max Heiland, Kilian Kreutzer, Steffen Koerdt, Leonard Knoedler

“…This study conducts a systematic review to describe the benefits and shortcomings of BSGs and ASGs across wound healing efficacy, tissue integration, immunogenicity, and functional outcomes focusing on wound re-epithelialization, graft survival, and overall aesthetic outcomes. …”
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The ubiquitin code of RAS proteins: Decoding its role in cancer progression by Yedan Shi, Yong Shen, Xiuyuan Zhang, Ning Zhu, Yuwei Ding, Ying Yuan, Juan Wang

“…We also analyze the heterogeneity of ubiquitination patterns across distinct RAS isoforms (KRAS4A, KRAS4B, NRAS, and HRAS) and their functional disparities in cancers. …”
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Microbial responses to ocean deoxygenation: Revisiting the impacts on organic carbon cycling by Quanrui Chen, Kai Tang, Weidong Zhai, Zhuoyi Zhu, Jin-Yu Terence Yang, Zhili He, Meng Li, Shuh-Ji Kao, Jun Yang, Qiang Zheng, Christian Lønborg, Helmuth Thomas, Nianzhi Jiao

“…This review explores the ecological functions of microbes under hypoxic and anoxic conditions, emphasizing their critical roles in carbon source-sink dynamics. …”
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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. by Ying Wu, Lindsay L Waite, Anne U Jackson, Wayne H-H Sheu, Steven Buyske, Devin Absher, Donna K Arnett, Eric Boerwinkle, Lori L Bonnycastle, Cara L Carty, Iona Cheng, Barbara Cochran, Damien C Croteau-Chonka, Logan Dumitrescu, Charles B Eaton, Nora Franceschini, Xiuqing Guo, Brian E Henderson, Lucia A Hindorff, Eric Kim, Leena Kinnunen, Pirjo Komulainen, Wen-Jane Lee, Loic Le Marchand, Yi Lin, Jaana Lindström, Oddgeir Lingaas-Holmen, Sabrina L Mitchell, Narisu Narisu, Jennifer G Robinson, Fred Schumacher, Alena Stančáková, Jouko Sundvall, Yun-Ju Sung, Amy J Swift, Wen-Chang Wang, Lynne Wilkens, Tom Wilsgaard, Alicia M Young, Linda S Adair, Christie M Ballantyne, Petra Bůžková, Aravinda Chakravarti, Francis S Collins, David Duggan, Alan B Feranil, Low-Tone Ho, Yi-Jen Hung, Steven C Hunt, Kristian Hveem, Jyh-Ming J Juang, Antero Y Kesäniemi, Johanna Kuusisto, Markku Laakso, Timo A Lakka, I-Te Lee, Mark F Leppert, Tara C Matise, Leena Moilanen, Inger Njølstad, Ulrike Peters, Thomas Quertermous, Rainer Rauramaa, Jerome I Rotter, Jouko Saramies, Jaakko Tuomilehto, Matti Uusitupa, Tzung-Dau Wang, Michael Boehnke, Christopher A Haiman, Yii-Der I Chen, Charles Kooperberg, Themistocles L Assimes, Dana C Crawford, Chao A Hsiung, Kari E North, Karen L Mohlke

“…Of 27 variants reported previously to have functional effects, 74% exhibited the strongest association at the respective signal. …”
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Reverse engineering neuron-type-specific and type-orthogonal splicing-regulatory networks using diverse cellular transcriptomes by Daniel F. Moakley, Melissa Campbell, Miquel Anglada-Girotto, Huijuan Feng, Andrea Califano, Edmund Au, Chaolin Zhang

“…Summary: Cell-type-specific alternative splicing (AS) enables differential gene isoform expression between diverse neuron types with distinct identities and functions. Current studies linking individual RNA-binding proteins (RBPs) to AS in a limited number of neuron types underscore the need for holistic modeling. …”
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The Scientific Benefits of a Statewide, Standardized, Coastal Wetland Monitoring Program in Hawaiʻi by Judith Z. Drexler, Helen Raine, Carrie L. Harrington, Kawika B. Winter, Kaʻuaʻoa Fraiola, Joy Browning, Jeff Burgett, David A. Burney, Kim Falinski, Scott Fisher, Kristen C. Harmon, Jessica L. Idle, Monica Iglecia, Mari‐Vaughn V. Johnson, Matthew Keir, K. Jackson Letchworth, Kirsten Moy, Anthony Olegario, Melissa R. Price, J. Michael Reed, Yoshimi M. Rii, Rachel Rounds, Charles B. vanRees, Bret Wolfe

“…A statewide, standardized, coastal wetland monitoring program with a centralized database would allow managers to keep better track of progress toward restoration goals, population changes of conservation‐reliant species, outbreaks and impacts of avian botulism, rates of coastal salinization, and many other critical issues across space and time. Monitoring combined with targeted research could fill critical knowledge gaps about the types, functions, values, and biodiversity of Hawaiian coastal wetlands. …”
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The impact of elevated CO2 on methanogen abundance and methane emissions in terrestrial ecosystems: A meta-analysis by Yiwen Ding, Mingyu Wang, Xiaojuan Du, Xue He, Tianle Xu, Xinyu Liu, Fuqiang Song

“…The results show that eCO2 promotes both the abundance of the functional methanogenic gene mcrA and CH4 emissions. …”
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Neonatal-Inspired Reprogramming of Microglial Pan-Programmed Cell Death Enhances Regeneration in Adult Spinal Cord Injury by Beibei Yu, Yongfeng Zhang, Yujie Yang, Shijie Yang, Haining Wu, Xue Gao, Yiming Hao, Shengyou Li, Bing Xia, Jintao Liu, Lingli Guo, Borui Xue, Mingze Qin, Huangtao Chen, Jianzhong Li, Shouping Gong, Teng Ma, Jinghui Huang

“…Accordingly, we developed “Thanatoset”, an SCI-specific gene panel to map tissue and cellular pan-PCD dynamics across neonatal and adult mice. Microglia were identified as pivotal mediators of pan-PCD, showing greater vulnerability in adults than in neonates. …”
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Graphene Microelectrode Arrays, 4D Structured Illumination Microscopy, and a Machine Learning Spike Sorting Algorithm Permit the Analysis of Ultrastructural Neuronal Changes During... by Meng Lu, Ernestine Hui, Marius Brockhoff, Jakob Träuble, Ana Fernandez‐Villegas, Oliver J Burton, Jacob Lamb, Edward Ward, Philippa J Woodhams, Wadood Tadbier, Nino F Läubli, Stephan Hofmann, Clemens F Kaminski, Antonio Lombardo, Gabriele S Kaminski Schierle

“…Abstract Simultaneously recording network activity and ultrastructural changes of the synapse is essential for advancing understanding of the basis of neuronal functions. However, the rapid millisecond‐scale fluctuations in neuronal activity and the subtle sub‐diffraction resolution changes of synaptic morphology pose significant challenges to this endeavor. …”
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Superelastic NiTi scaffolds with extensively tuneable mechanical and mass transfer properties by Shiyu Zhong, Lei Zhang, Ying Li, Wanying Wang, Gan Li, Yulun Luo, Dingfei Zhang, Jian Lu

“…Natural bones exhibit a substantial recoverable strain ( ϵ _rec ) of 2%‒4% and vary in mechanical and mass transfer properties across different body regions. Integrating these attributes is essential for the functionality and therapeutic efficacy of metallic scaffolds used in bone defect treatment. …”
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Gut microbiota contribute to high-altitude adaptation in tree sparrows by Tingbei Bo, Gang Song, Mengru Zhang, Xiaoming Xu, Jundong Duan, Huishang She, Yun Fang, Wenting Li, Jing Wen, Jingsong Liu, Dehua Wang, Fumin Lei

“…Therefore, we employed a multidisciplinary approach combining amplicon sequencing, transcriptome analysis, and fecal microbiota transplantation (FMT) to investigate the functional role of gut microbiota in high-altitude tree sparrows across different seasons. …”
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COL10A1+ fibroblasts promote colorectal cancer metastasis and M2 macrophage polarization with pan-cancer relevance by Shangshang Hu, Muzi Ding, Jinwei Lou, Jian Qin, Yuhan Chen, Zixuan Liu, Yue Li, Junjie Nie, Mu Xu, Huiling Sun, Xinliang Gu, Tao Xu, Shukui Wang, Shukui Wang, Yuqin Pan

“…Pan-cancer analysis suggests that COL10A1+Fib may have similar functional roles across multiple major solid tumors. …”
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Gut Microbiota Diversity in 16 Stingless Bee Species (Hymenoptera: Apidae: Meliponini) by María de Lourdes Ramírez-Ahuja, Kenzy I. Peña-Carrillo, Mayra A. Gómez-Govea, Mariana Lizbeth Jiménez-Martínez, Gerardo de Jesús Trujillo-Rodríguez, Marisol Espinoza-Ruiz, Antonio Guzmán Velasco, Adriana E. Flores, José Ignacio González-Rojas, Diana Reséndez-Pérez, Iram Pablo Rodríguez-Sánchez

“…Bacterial symbionts play an important role in insect survival by contributing to key metabolic and defensive functions. While stingless bees are known to harbor diverse microbial communities, their core bacterial symbionts remain poorly characterized. …”
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Deciphering consciousness: The role of corticothalamocortical interactions in general anesthesia by Yuxi Zhou, Shiqian Huang, Tianhao Zhang, Daling Deng, Li Huang, Xiangdong Chen

“…This review elucidates how anesthetics impair corticothalamocortical interactions, thereby affecting the flow of information across various cortical layers and disrupting higher-order cognitive functions while preserving basic sensory processing. …”
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PSD3 as a context-dependent modulator of immune landscape and tumor aggressiveness in esophageal squamous cell carcinoma by Shujuan Luo, Huifang Li, Bangwu Cai, Aididar Nurbahati, Hong Cui, Tianyuan Peng, Wei Wang, Qing Liu, Xiaomei Lu, Shutao Zheng

“…CD274 and TNFSF18 were consistently up-regulated in ESCC across both TCGA and GEO datasets, while PSD3 showed significantly higher expression in TCGA but no significant difference in the GEO cohort. …”
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UniMap: Type‐Level Integration Enhances Biological Preservation and Interpretability in Single‐Cell Annotation by Haitao Hu, Yue Guo, Fujing Ge, Hao Yin, Hao Zhang, Zhesheng Zhou, Fangjie Yan, Qing Ye, Jialu Wu, Ji Cao, Chang‐Yu Hsieh, Bo Yang

“…Here, a multiselective adversarial network is introduced for the first time and present UniMap, which functions as a “discerner” to identify and exclude interfering cells from various data sources during dataset integration. …”
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