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  1. 14501

    How Traditional Chinese Medicine Can Play a Role In Nanomedicine? A Comprehensive Review of the Literature by Wang C, Ren K, Yang M, Li X, Li N, Li P, Yang H, Zhang G, Wei X

    Published 2025-05-01
    “…Chi Wang,1,2 Kaixiang Ren,1,2 Mei Yang,1,2 Xiang Li,3 Ningxi Li,4 Peng Li,1,2 Huang Yang,5,6 Guangjian Zhang,1,2 Xiaodan Wei1,2 1Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China; 2Key Laboratory of Enhanced Recovery After Surgery of Intergrated Chinese and Western Medicine, Administration of Traditional Chinese Medicine of Shaanxi Province, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China; 3Department of Ophthalmology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China; 4Mianyang Key Laboratory of Anesthesia and Neuroregulation, Department of Anesthesiology, Mianyang Central Hospital, Mianyang, 621000, People’s Republic of China; 5Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, People’s Republic of China; 6MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310003, People’s Republic of ChinaCorrespondence: Xiaodan Wei; Guangjian Zhang, Department of Thoracic Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Email weixiaodan@xjtufh.edu.cn; michael8039@xjtu.edu.cnAbstract: Traditional Chinese medicine (TCM), a time-honored practice rooted in natural therapeutics, has served as a cornerstone in safeguarding human health across millennia, aiding in disease mitigation and life vitality preservation. …”
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  2. 14502

    Predicting abatacept retention using machine learning by Rieke Alten, Claire Behar, Pierre Merckaert, Ebenezer Afari, Virginie Vannier-Moreau, Anael Ohayon, Sean E. Connolly, Aurélie Najm, Pierre-Antoine Juge, Gengyuan Liu, Angshu Rai, Yedid Elbez, Karissa Lozenski

    Published 2025-02-01
    “…Patient demographic and disease characteristics were input across 10 machine learning models used to predict 12-month treatment retention. …”
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  3. 14503

    Direct RNA sequencing reveals chicken post-transcriptional modifications in response to Campylobacter jejuni inoculation by Yanan Zhao, Yuanmei Wang, Yanru Ren, Long Liu, Tianyi Wang, Liying Liu, Xianyao Li

    Published 2025-04-01
    “…Post-transcriptional modifications play crucial roles in regulating the immune system and cell functions. However, the epigenetic regulation in response to C. jejuni inoculation in chicken remains elusive. …”
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  4. 14504
  5. 14505

    Progressive Response of Repeated Treatment with High-Concentration (179 mg) Capsaicin Patch in Peripheral Neuropathic Pain After Surgical or Traumatic Nerve Injury: Findings from t... by Michael A. Überall, Christian Simanski, Mike Zellnig, Mariëlle Eerdekens, Sylvia Engelen, Myriam Heine, Fabienne Percot, Rita Freitas, Lucia Garcia Guerra, Tamara Quandel

    Published 2025-06-01
    “…Key measures included pain intensity, quality of life (QoL), affective distress, sleep disturbances, and overall functioning. Furthermore, analgesic use and adverse events associated with HCCP treatment were evaluated. …”
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  6. 14506
  7. 14507

    NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis by Shichao Li, Yulan Wang, Xi Yang, Miao Li, Guoxiang Li, Qiangqiang Song, Junyu Liu

    Published 2025-03-01
    “…Nevertheless, the precise biological functions and clinical implications of CBC in cancer remain ambiguous, necessitating further investigation for clarification. …”
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  8. 14508

    Spatiotemporal dynamics of benzylisoquinoline alkaloid gene expression and co-expression networks during Papaver Somniferum developmental stages by Zishi Wang, Quanzheng Yun, Jinyuan Hu, Zhen Wei, Deri Feng, Ning Li, He Xu, Lihong Fu, Zhenlong Wang, Shujin Li, Fangru Liu, Yan Wang, Bin Cong, Baishi Wang

    Published 2025-07-01
    “…Key genes such as TYDC, PPO, and GsSRK demonstrated distinct regulatory roles during flowering and fruit maturation. Functional enrichment analysis uncovered critical pathways and transcription factors involved in alkaloid production. …”
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  9. 14509
  10. 14510

    Introduction by Verena Balz

    Published 2019-07-01
    “…Upcoming approaches, often called spatial planning, moved attention from the planning of predefined, contained territories to the planning of spatial networks, stretching across multiple and multi-scalar administrative boundaries. …”
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  11. 14511

    Molecular Characterization and Feeding-Associated Expression Dynamics of the Period Gene Family in Channel Catfish (<i>Ictalurus punctatus</i>) by Hongyan Liu, Shiyong Zhang, Xiaohui Chen, Minghua Wang, Liqiang Zhong, Yongqiang Duan, Bingjie Xie, Luyu Tang, Yi Cheng

    Published 2025-06-01
    “…In teleost fish, including channel catfish (<i>Ictalurus punctatus</i>), these genes have evolved distinct functions. However, the evolutionary characteristics and functional roles of period genes, particularly in response to environmental cues such as feeding, remain unclear. …”
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  12. 14512

    Skin Microbiome Overview: How Physical Activity Influences Bacteria by Cristina Mennitti, Mariella Calvanese, Alessandro Gentile, Aniello Vastola, Pietro Romano, Laura Ingenito, Luca Gentile, Iolanda Veneruso, Carmela Scarano, Ilaria La Monica, Ritamaria Di Lorenzo, Giulia Frisso, Valeria D’Argenio, Barbara Lombardo, Olga Scudiero, Raffaela Pero, Sonia Laneri

    Published 2025-04-01
    “…The skin cannot be considered as just a barrier that protects against physical, chemical, and biological damage; it is a complex and dynamic ecosystem that varies across lifespans. Interest in the relationship between physical activity and skin microbiota has grown significantly in recent years. …”
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  13. 14513

    Modality-level obstacles and initiatives to improve representation in fetal, infant, and toddler neuroimaging research samples by Emma T. Margolis, Paige M. Nelson, Abigail Fiske, Juliette L.Y. Champaud, Halie A. Olson, María José C. Gomez, Áine T. Dineen, Chiara Bulgarelli, Sonya V. Troller-Renfree, Kirsten A. Donald, Marisa N. Spann, Brittany Howell, Dustin Scheinost, Marta Korom

    Published 2025-04-01
    “…Inclusive and representative samples are essential for generalizing findings across neuroimaging modalities, such as magnetic resonance imaging, magnetoencephalography, electroencephalography, functional near-infrared spectroscopy, and cranial ultrasonography. …”
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  14. 14514

    ApoBDs: a paradigm shift from cellular debris to therapeutic vehicles by Zixuan Xiong, Zixuan Xiong, Fen Xiao, Yuanyuan Sun, Yuanyuan Sun, Hankun Su, Hankun Su, Di Liu, Di Liu, Boya Tang, Boya Tang, Wenyan Jian, Tianli Yang, Tianli Yang, Jing Zhao, Jing Zhao, Yanping Li, Yanping Li, Hui Li, Hui Li

    Published 2025-07-01
    “…This review focus on the origins, formation mechanisms, and dual functions of ApoBDs across various diseases, highlighting their paradoxical nature as both disease promoters and therapeutic allies. …”
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  15. 14515

    Development of KASP markers for FT family genes in soybean by Hui Jiang, Xin Xu, Yanhui Sun, Peiguo Wang, Lixin Zhang, Mahmoud Naser, Shi Sun, Jidao Du, Tianfu Han

    Published 2025-06-01
    “…In this study, we identified 10 FT family genes in soybean and examined their functional divergences through sequence alignment analysis. …”
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  16. 14516

    Expression and clinical significance of FANCI gene in pan-cancer: a comprehensive analysis based on multi-omics data by Yunzheng Zhao, Yunzheng Zhao, Qingyu Li, Qingyu Li, Jiajun Li, Jiajun Li, YiFeng Cui, YiFeng Cui, Zhaoyang Lu, Zhaoyang Lu

    Published 2025-05-01
    “…This investigation seeks to clarify the expression profiles, prognostic relevance, and diagnostic capabilities of FANCI across multiple malignancies, along with its links to immune cell infiltration, genetic alterations, protein-protein interactions, and functional roles.MethodsBy utilizing data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases, we conducted a comprehensive analysis of FANCI mRNA expression using R software and visualized the results with the ggplot2 package. …”
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  17. 14517

    Tea Plant/<i>Ophiopogon japonicus</i> Intercropping Drives the Reshaping of Soil Microbial Communities in Terraced Tea Plantation’s Micro-Topographical Units by Yangxin Li, Le Sun, Jialin Zhang, Hongxue Zhao, Tejia Su, Wenhui Li, Linkun Wu, Pumo Cai, Christopher Rensing, Yuanping Li, Jianming Zhang, Feiquan Wang, Qisong Li

    Published 2025-05-01
    “…This study investigates the effects of intercropping <i>Ophiopogon japonicus</i> in a five-year tea plantation on the soil physicochemical properties, enzyme activities, and microbial community structure and functions across different micro-topographical features of terraced tea plantations in Wuyi Mountain. …”
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  18. 14518

    THE EFFECTIVENESS OF COMBINATION THERAPY WITH BOSENTAN AND SILDENAFIL IN PATIENTS WITH THE CLINICAL WORSENING OF IDIOPATHIC PULMONARY HYPERTENSION ON THE BACKGROUND OF SPECIFIC MON... by V. M. Paramonov, T. V. Martynyuk, Yu. G. Matchin, V. P. Masenco, S. N. Nakonechnikov, I. Ye. Chazova

    Published 2016-12-01
    “…Material and Methods: the study included 50 patients with IPAH nonresponders functional class (FC) II-III (WHO). Patients were randomized into 2 groups of 1: 1 bosentan therapy at the starting dose of 125 mg/day titrated up to 250 mg across 4 weeks and sildenafil 60 mg/day. …”
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  19. 14519
  20. 14520

    Enhancing the effects of nusinersen with cybernic treatment using Hybrid Assistive Limb (HAL) in spinal muscular atrophy: a real-world case series and exploratory cohort analysis by Takashi Nakajima, Toshio Saito, Akihiro Hashiguchi, Taiki Nakabayashi, Kazuki Kodera, Kota Utsumi, Takeshi Kanayama, Haruka Urabe, Satoru Kinoshita

    Published 2025-04-01
    “…Abstract Background Nusinersen therapy for spinal muscular atrophy (SMA) provides significant functional improvement when initiated pre-symptomatically or early in life. …”
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