The impact of interactions between heavy metals and smoking exposures on the formation of oral microbial communities by Qiwen Zheng, Yonghua Zhang, Jia Li, Shuwei Pei, Jiangyun Liu, Lu Feng, Li Zhang, Xingrong Liu, Bin Luo, Ye Ruan, Weigang Hu, Jingping Niu, Tian Tian

“…By comparing the oral bacterial communities and functional pathways between the four groups, we found significant differences in bacterial communities and functional pathways between the groups. …”
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The RELN heterozygous single-nucleotide polymorphism rs362691 increases the prefrontal cortical thickness and modulates systemizing-related autistic tendencies in typically develop... by Hiroki Sato, Hiroki Sato, Hiroki Sato, Mitsunari Abe, Mitsunari Abe, Hikaru Takeuchi, Hiroaki Tomita, Shigeo Kure, Shigeo Kure, Ryuta Kawashima, Yasuyuki Taki

“…Animal and human studies suggest that insufficient reelin signaling due to RELN mutations may alter the functional properties of the prefrontal cortex and contribute to cortical dysplasia in the frontal and temporal lobes. …”
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Identification of novel candidate loci for Alzheimer’s disease and related dementias by leveraging the shared genetic basis with hippocampal volume by Chenyang Jiang, Sven J. van der Lee, Niccolò Tesi, Wiesje M. van der Flier, Betty M. Tijms, Lianne M. Reus

“…Functional annotation and phenome-wide association studies (PheWAS) were performed on the identified shared loci to characterize their biological relevance. …”
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Metagenome Analysis Identified Novel Microbial Diversity of Sandy Soils Surrounded by Natural Lakes and Artificial Water Points in King Salman Bin Abdulaziz Royal Natural Reserve,... by Yahya S. Al-Awthan, Rashid Mir, Fuad A. Alatawi, Abdulaziz S. Alatawi, Fahad M. Almutairi, Tamer Khafaga, Wael M. Shohdi, Amal M. Fakhry, Basmah M. Alharbi

“…Additionally, metagenomic studies offer valuable insights into the composition and functional potential of soil microbial communities. …”
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Understanding ecohydrology and biodiversity in aquatic nature-based solutions in urban streams and ponds through an integrative multi-tracer approach by M. M. Warter, D. Tetzlaff, D. Tetzlaff, D. Tetzlaff, C. Soulsby, C. Soulsby, C. Soulsby, T. Goldhammer, D. Gebler, K. Vierikko, M. T. Monaghan, M. T. Monaghan

“…Our findings emphasize the utility of integrated tracer approaches to explore the interface between ecology and hydrology and provide insights into the ecohydrologic functioning of aquaNBSs and their potential limitations. …”
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GG-NER’s role in androgen receptor signaling inhibitor response for advanced prostate cancer by Chuanfan Zhong, Jiaxing Wang, Hangyang Peng, Jianming Lu, Zining Long, Zhuoyuan Lin, Guo Chen, Chao Cai, Shilong Cheng, Zhongjie Chen, Le Zhang, Weibo Zhong, Rujun Mo, Xiangming Mao

“…Additionally, we mapped tumor mutations to delineate the mutational landscapes across different risk groups and explored functional pathways through GO, KEGG, and GSEA analyses. …”
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Effect of age on the efficacy and safety of Panax notoginseng saponins in acute ischemic stroke: a prespecified secondary analysis of the PANDA study by Tingting Li, Anxin Wang, Xiaoli Zhang, Luda Feng, Peipei Du, Ying Gao, Xunming Ji, Haiqing Song, Chi Zhang

“…The primary outcome of this study was functional independence at the 3-month follow-up, as indicated by a modified Rankin Scale score (mRS) ranging from 0 to 2. …”
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The Requirements and Development Potential of Interdisciplinary Digital Health Data Exchange in Mobile Nursing and Care Settings in German-Speaking Countries: Delphi Study by Verena Kollmann, Nathalie Traugott, Susanne Hensely-Schinkinger, Doris Zeidler, Elisabeth Haslinger-Baumann

“…The first round included 159 items rated on a 4-point Likert scale and a ranking task of EHR functions. In the second round, only items without prior consensus and the top-ranked functions were reassessed. …”
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A diverse set of solubilized natural fibers drives structure-dependent metabolism and modulation of the human gut microbiota by Maria X. Maldonado-Gomez, Katharine M. Ng, Riley A. Drexler, Alexandria M. S. Conner, Cory G. Vierra, Nithya Krishnakumar, Hannah M. Gerber, Zachary R. Taylor, Jenna L. Treon, Megan Ellis, Jada K. A. Garcia, James P. Cerney, David G. Chapin, Robnet T. Kerns, Angela M. Marcobal, Steven M. Watkins, Matthew J. Amicucci

“…We performed a comprehensive structural characterization and functional evaluation of a unique and highly diverse set of new, highly soluble fibers with varied monosaccharide compositions, glycosidic linkages, and polymer lengths. …”
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A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

“…A prognostic model was built with Cox and Least Absolute Shrinkage and Selection Operator (LASSO) methods and validated by Kaplan-Meier analysis, Receiver Operating Characteristic (ROC) curves, and Principal Component Analysis (PCA). Functional analysis revealed immune infiltration and drug sensitivity differences. …”
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Well-Being in Psoriasis: Weighting its Components Using Best-worst Scaling Methodology by Esteban Daudén, Isabel Belinchón, Elena Colominas-González, Pablo Coto, Pablo de la Cueva, Fernando Gallardo, Jose Luis Poveda, Esther Ramírez, Sandra Ros, Ricardo Ruíz-Villaverde, Isabel Cabezas, Luis Lizán

“…The five key components for patients were pain (P: 100.00), stress (P: 98.74), treatment satisfaction (92.21), itching (72.05), and lesions in functional locations (P: 69.09). From a HCP perspective, the most important components were mood disorders (100.00), pain (69.39), lesions in functional locations (49.34), self-esteem (49.24), and stigmatization/shame (45.22). …”
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A comprehensive transcriptome based meta-analysis to unveil the aggression nexus of oral squamous cell carcinoma by Soujanya J. Vastrad, Ganesan Rajalekshmi Saraswathy, Jagadish B. Dasari, Gouri Nair, Ashok Madarakhandi, Dominic Augustine, S.V. Sowmya

“…Key determinants of disease progression are identified through functional characterization and the TopConfects ranking approach of nodal associated differentially expressed genes (DEGs). …”
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AI-based system for food and beverage selection towards precision nutrition in Indonesian restaurants by Kudang Boro Seminar, Evy Damayanthi, Karlisa Priandana, Harry Imantho, Bonang Waspadadi Ligar, Annisa Utami Seminar, Angga Dwi Krishnajaya, Muhamad Reza Aditya, Muhammad Ilham Hakim Suherman, Ismy Fana Fillah

“…The diversity of foods, where each dish may have a unique recipe across different restaurants, needs to be accounted for in personalized nutrition. …”
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Trophic Change and Community Decline in Acrobat Ants After Rainforest Conversion to Cash Crops by Jessica Ehlers, Tamara R. Hartke, Noah Janotta, Amanda Mawan, Rizky Nazarreta, Rizky Desriana, Purnama Hidayat, Damayanti Buchori, Stefan Scheu, Melanie M. Pollierer, Jochen Drescher

“…ABSTRACT The conversion of tropical rainforests to agriculture causes population declines and biodiversity loss across taxa. This impacts ants (Formicidae), a crucial tropical group for ecosystem functioning. …”
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Addressing ORPD problem in a standard IEEE power network accompanied with RESs and FACTs appliances by COMMKE under volatile load scenarios by Susanta Dutta, Tushnik Sarkar, Chandan Paul, Sabbir Reza Tarafdar, Provas Kumar Roy, Ghanshyam G. Tejani, Seyed Jalaleddin Mousavirad

“…This research examines the optimal reactive power dispatch (ORPD) problem across IEEE 30 & 118 bus experimental networks. …”
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The insula represents a key neurobiological pain hub in psoriatic arthritis by Flavia Sunzini, Kristian Stefanov, Salim Al-Wasity, Chelsea Kaplan, Andrew Schrepf, Noah Waller, Steven Harte, Richard Harris, Daniel J. Clauw, John McLean, Stefan Siebert, Carl S. Goodyear, Gordon D. Waiter, Neil Basu

“…Nociceptive and nociplastic mechanisms are clinically challenging to distinguish. Advances in brain functional magnetic resonance imaging (fMRI) have successfully characterised distinct pain mechanisms across several disorders, in particular implicating the insula. …”
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RNA silencing response in chloroplast-replicating viroid siRNA biogenesis in plants by Pengcheng Zhang, Xinlian Zhang, Atef M. Mohamed, Leizhen Wang, José-Antonio Daròs, Shifang Li, Mahmut Tör, Yiguo Hong

“…Abstract RNA silencing represents a cellular regulatory and defence mechanism in eukaryotes across kingdoms. In plants, a combined functionality of DCL2 and DCL3 is crucial for their synergistic defence against whilst DCL4 is required for nucleus-replicating viroid. …”
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Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion by Cristina Cirauqui, Laura Ojeda, Itziar Otano, Irene Pazos, Alba Santos, Eva M. Garrido‐Martín, Patricia Yagüe, Javier Ramos‐Paradas, Sonia Molina‐Pinelo, Giovanna Roncador, José Luis Solórzano, M. Teresa Muñoz, Patricia Cozar, Patricia Plaza, Rocío Suárez, Marta Jiménez, Roberto Moreno, Arantxa Rosado, Pablo Gámez, Ricardo García‐Luján, Jon Zugazagoitia, E. Alejandro Sweet‐Cordero, Mariano Barbacid, Amancio Carnero, Irene Ferrer, Luis Paz‐Ares

“…Abstract Rationale Interleukin‐11 (IL‐11) has emerged as a significant player in tumourigenesis, with implications across various cancer types. However, its specific role in driving tumour progression in lung adenocarcinoma (LUAD) remains elusive. …”
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Formation control method for multiple flight vehicles based on adaptive dynamic programming by Jie XIAO, Qingpu TANG, Jiale LI, Guofei LI

“…Unmanned aerial vehicles (UAVs) are widely used across various fields, including atmospheric research, emergency rescue, and cargo transportation, demonstrating their versatility and efficiency in both civil and military applications. …”
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Genome sequence of a European Diplocarpon coronariae strain and in silico structure of the mating-type locus by Sophie Richter, Sophie Richter, Sabine Kind, Thomas Oberhänsli, Michael Schneider, Natalia Nenasheva, Katharina Hoff, Jens Keilwagen, Il-Kweon Yeon, Vincent Philion, Shigeki Moriya, Henryk Flachowsky, Andrea Patocchi, Thomas Wolfgang Wöhner

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