A roadmap towards targeted differentiation of mouse trophoblast stem cells into cell types of the feto-maternal exchange surface by Noura Ballasy, Bethany N. Radford, Shuhiba Mohammad, Wendy Dean, Myriam Hemberger

“…This mix of differentiating cells is a particular impediment for functional investigations into the roles of specific trophoblast subtypes of the mouse placental labyrinth, i.e. the portion of the placenta that establishes the feto-maternal exchange unit. …”
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Genome-Wide Identification of <i>UGT</i> Genes and Analysis of Their Expression Profiles During Fruit Development in Walnut (<i>Juglans regia</i> L.) by Danhua Shi, Jinyu Yang, Gengyang Li, Yuanting Zhou, Pei Yao, Yanyu Shi, Jieyun Tian, Xiaojun Zhang, Qunlong Liu

“…This comprehensive study provides an overview of the <i>UGT</i> genes in walnut, serving as a valuable reference and theoretical foundation for further investigations into the biological functions of <i>JrUGTs</i> in flavonoid biosynthesis.…”
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Integrated Analysis to Reveal Heterogeneity of Tumor‐Associated Neutrophils in Glioma by Wen Wang, Junsheng Li, Qiheng He, Chenglong Liu, Siyu Wang, Zhiyao Zheng, Bojian Zhang, Siqi Mou, Wei Sun, Jizong Zhao

“…In vitro experiments were also performed for functional verification, including CCK8, EdU, Transwell, and TUNEL assays. …”
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Taguchi Method-Based Synthesis of a Circular Antenna Array for Enhanced IoT Applications by Wided Amara, Ramzi Kheder, Ridha Ghayoula, Issam El Gmati, Amor Smida, Jaouhar Fattahi, Lassaad Latrach

“…By investigating alternative planar array designs and their synthesis methods, this research seeks to provide solutions that improve coverage, reduce interference from secondary lobes, and ultimately enhance the functionality of antennas in diverse applications, including telecommunications, radar systems, and wireless communication.…”
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Development and validation of the Aarhus Structured Clinical Interview for Prolonged Grief Disorder in ICD-11 and DSM-5-TR (A-PGDi) by Maja O’Connor, Maria Louison Vang, Richard A. Bryant, Christina Buur, Katrine B. Komischke-Konnerup, Lisbeth Frostholm, Nicolai Ladegaard

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Physiology and Growth Performance of Gallus gallus domesticus Supplemented with Algal Extracts by ZU Abideen, M Farooq, T Ruby, AA Khan

“…The experiment included 70 chickens grouped across seven treatment groups consisting of a control group along with Spirulina doses from 0.25g/L to 5g/L, and CVE doses from 0.25g/L to 5g/L. …”
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Effect of diet combined with exercise intervention on tumor necrosis factor α in overweight or obese groups: Based on the exercise dose-response relationship by Chuan qiu shui Wang, Kun Wang, Shi qi Liu, Liang Sun, Jiong Luo

“…Methods: A thorough search was conducted across four electronic databases of randomized controlled trials that focus on exercise or dietary interventions for patients with obesity or overweight. …”
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Global trends and regional disparities in the burden of headache disorders, 1990–2021: a comprehensive analysis of the global burden of disease study by Yuanyuan Rui, Bing Wu, Qian Li, Kai Zhang

“…BackgroundHeadache disorders significantly impact health and functioning, yet studies on their global burden across all age groups are limited. …”
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Nitrogen addition promotes the coupling of deep soil carbon and nitrogen under different vegetation restoration types in the Chinese Loess Plateau by Shihao Gong, Xiaoxia Zhang, Hengshuo Zhang, Lianwei Gao, Tonggang Zha

“…Carbon-nitrogen coupling is important to maintain various functions in forest ecosystems and is thus, an important indicator of forest ecosystem health. …”
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COVID-19 Vaccination Uptake and Effectiveness for Hospitalized Cases Among Healthcare Workers in Tertiary Hospital by María Eugenia Jiménez-Corona, Luis-Pablo Cruz-Hervert, María del Rocío Sánchez-Díaz, Gabriel Chavira-Trujillo, Aída Jiménez-Corona, María del Rosario Vázquez-Larios

“…Vaccination among HCWs was a key strategy to mitigate severe outcomes and maintain healthcare system functionality during the crisis. The aim of this study was to assess the distribution, severity, and clinical factors associated with COVID-19 among HCWs in a tertiary hospital across eight pandemic waves and evaluate the effectiveness of vaccination in reducing severe outcomes. …”
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Comparative effects of pharmacological interventions for the prevention of acute mountain sickness: A systematic review and Bayesian network meta-analysis by Junyan Wang, Nan Lian, Kuo Tang, Yan Deng, Tao Li

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Fatty acid metabolism shapes immune responses in chronic lymphocytic leukemia by Yang Zhang, Jun Ma, Peipei Li, Kang Lu, Yang Han, Xinting Hu, Xiaosheng Fang, Xin Wang, Ya Zhang

“…Single-cell analysis revealed distinct expression patterns of LPL, SOCS3, and CNR1 across CLL immune cell subsets. Cellular communication analysis highlighted the regulatory role of distinct B cell and Treg subsets in the CLL microenvironment. …”
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Subtype-specific atypical B cell profiles in myasthenia gravis reveal distinct immunopathological pathways by Patricia M. Sikorski, Henry J. Kaminski, Angela Vincent, Taylor Bauman, Leslie Jacobson, Linda L. Kusner

“…IntroductionAtypical B cell (atBC) subsets display significant heterogeneity across autoimmune diseases, complicating efforts to define their role and therapeutic potential. …”
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Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes by Beata Stepniak, Anne Kästner, Giulia Poggi, Marina Mitjans, Martin Begemann, Annette Hartmann, Sandra Van der Auwera, Farahnaz Sananbenesi, Dilja Krueger‐Burg, Gabriela Matuszko, Cornelia Brosi, Georg Homuth, Henry Völzke, Fritz Benseler, Claudia Bagni, Utz Fischer, Alexander Dityatev, Hans‐Jörgen Grabe, Dan Rujescu, Andre Fischer, Hannelore Ehrenreich

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Optimizing Energy and Spectral Efficiency in Mobile Networks: A Comprehensive Energy Sustainability Framework for Network Operators by Luis Mata, Marco Sousa, Pedro Vieira, Maria Paula Queluz, Antonio Rodrigues

“…This paper introduces the Energy Sustainability Framework, which provides a composite index to evaluate the spectral and energy efficiencies of BSs, summarised across four classes: A, B, C, and D. This framework supports network auditing, benchmarking, monitoring, and energy efficiency optimization while ensuring the desired Quality of Service (QoS). …”
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Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer’s Disease by Zhiwu Dong, Kewen Zhao, Hongjun Gu, Wenwei Yang, Xin Zhang

“…Moreover, CTBP1 expression levels significantly varied across multiple GEO datasets. …”
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Effectiveness of advance care planning programmes in improving end-of-life outcomes for individuals with dementia and their caregivers in nursing homes: protocol for a systematic r... by Chih-Cheng Lai, Yu-Tai Lo, Yi-Jhen Chen, Jheng-Yan Wu

“…The unpredictable trajectory of the disease, marked by cognitive and functional decline, necessitates intensive healthcare and poses challenges to end-of-life (EoL) care decisions, particularly because majority of the affected individuals become unable to make their own decisions. …”
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Context-dependent modulations of subthalamo-cortical synchronization during rapid reversals of movement direction in Parkinson’s disease by Lucie Winkler, Markus Butz, Abhinav Sharma, Jan Vesper, Alfons Schnitzler, Petra Fischer, Jan Hirschmann

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Microbial biomass – not diversity – drives soil carbon and nitrogen mineralization in Spanish holm oak ecosystems by Elisa Bruni, Jorge Curiel Yuste, Lorenzo Menichetti, Omar Flores, Daniela Guasconi, Bertrand Guenet, Ana-Maria Hereș, Aleksi Lehtonen, Raisa Mäkipää, Marleen Pallandt, Leticia Pérez-Izquierdo, Etienne Richy, Mathieu Santonja, Boris Tupek, Stefano Manzoni

“…Incorporating microbial properties, and especially diversity, into ecosystem models remains an open question, requiring careful consideration of the tradeoff between model complexity and performance.This work addresses this knowledge gap by implementing a simple C and nitrogen (N) cycling model to predict heterotrophic respiration and net N mineralization rates in soils sampled under different land-uses and tree health conditions across Spain. To understand the role of microorganisms on ecosystem functioning, we progressively incorporated microbial biomass and diversity (i.e., alpha diversity of taxa and of fungal functional groups), and selected the model that optimized prediction accuracy, while minimizing complexity.We found that microbial biomass had a strong and positive effect on both C and N mineralization rates, with heterotrophic respiration being nearly linearly controlled by biomass. …”
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Structures and determinants of soil microbiomes along a steep elevation gradient in Southwest China by Ting Li, Ting Li, Ting Li, Ziyan Gao, Ping Zhou, Ping Zhou, Mingmin Huang, Gangzheng Wang, Jianping Xu, Wangqiu Deng, Mu Wang, Mu Wang

“…Soil microbial communities play a vital role in accelerating nutrient cycling and stabilizing ecosystem functions in forests. However, the diversity of soil microbiome and the mechanisms driving their distribution patterns along elevational gradients in montane areas remain largely unknown. …”
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