Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach by Yanggang Hong, Deqi Wang, Zeyu Liu, Yuxin Chen, Yi Wang, Jiajun Li

“…These targets were further validated via bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics, which revealed differential expression patterns across various cell types in the HCC tumor microenvironment. …”
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Deciphering the role of Hashimoto's Thyroiditis-related key genes in thyroid cancer via detailed in silico analysis followed by the experimental validation by Mostafa A. Abdel-Maksoud, Taghreed N. Almana, Saeedah Almutair, Abdulaziz Alamri, Ibrahim A. Saleh, Mohamed Y. Zaky, Wahidah H. Al-Qahtani, Yasir Hameed

“…Bisulfite sequencing demonstrated increased promoter methylation across all eight genes in cancerous samples, suggesting epigenetic silencing as a regulatory mechanism. …”
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Efficient Resource Allocation and UAV Deployment in STAR-RIS and UAV-Relay Assisted Public Safety Networks for Video Transmission by Naveed Khan, Ayaz Ahmad, Abdulmalik Alwarafy, Munam Ali Shah, Abderrahmane Lakas, Muhammad Moazam Azeem

“…Specifically, the average percentage improvement across all benchmarks is approximately 45%, underscoring the effectiveness of our approach.…”
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Quantitative EEG signatures in patients with and without epilepsy development after a first seizure by Marysol Segovia‐Oropeza, Erik Hans Ulrich Rauf, Ev‐Christin Heide, Niels K. Focke

“…Quantitative EEG analysis and functional connectivity (FC) have shown promise in identifying patterns across epilepsy syndromes. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…This comorbidity can significantly impair the quality of life, particularly in adolescents with high-functioning ASD, where the prevalence reaches 41.98%. …”
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Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling by Hyun-Jee Han, Marcos Rubio-Alarcon, Thomas Allen, Sunwoo Lee, Taufiq Rahman

“…Their differential expressions across various cancer types are specific to NRP isoforms which are shown in a cancer type-dependent manner. …”
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Protocol for a cluster-randomized clinical trial to evaluate the effectiveness of mindfulness-based cognitive therapy for depression, implemented in Vietnamese Buddhist pagoda by Bahr Weiss, Van Vu, Hoang-Minh Dang, Lam Trung

“…There will be five longitudinal assessments: Screening, and T1, T2, T3, and T4 across four months from baseline. One hundred and sixty participants will be recruited for eight Buddhist pagoda (four treatment; four control) around Hanoi, Vietnam. …”
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Simple and Discriminatory Reaction Times in Preovulatory and Postovulatory Phases of Menstrual Cycle in Healthy Young Females: A Cross-sectional Study by Hemalatha Manjeshwara, V Suganthi, Amudharaj Dharmalingam, Milind V Bhutkar, Gopinath Manavazhagan

“…Introduction: The menstrual cycle plays a significant role in the functioning of the cardiovascular and central nervous systems. …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…Person misfit did not degrade item measures or model statistics. Differential item functioning (DIF) was noted for the three easiest items on specific days. …”
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Quantitative assessment of the potential of retail outlets by K. A. Lychagin

“…The  proposed method  is based on the analog method of comparing outlets and uses the methods of clustering outlets across a wide range of indicators. The  results of approbation of the approach on the data for 33 regions of the Russian  Federation are given. …”
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Psychometric evaluation of the Chinese version of the Patient Self-Advocacy Scale using classical test theory and item response theory by Jialu Cui, Jing Wang, Ailin Yue, Jiayan Cao, Zhijie Zhang, Baoxin Shi

“…The Wright map showed good matching between item difficulty and person ability. Differential item functioning (DIF) analysis revealed no significant differences across gender. …”
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consHLA: a next generation sequencing consensus-based HLA typing workflow by Rachel Bowen-James, Weilin Wu, Marie Wong-Erasmus, Julian M. W. Quinn, Chelsea Mayoh, Mark J. Cowley

“…Abstract Background Human Leukocyte Antigens (HLA) play central roles in histocompatibility and immune system functions, including antigen presentation. Accurate typing of Class I and II HLA genes is crucial for transplant tissue matching, characterising autoimmune diseases and informing cancer immunotherapy. …”
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Co-Designed Online Training Program for Worry Management: The Role of Young People With Lived Experience of Worry in Program Development by Jessica Steward, Michelle L Moulds, Colette R Hirsch

“…ResultsFeedback from LEAP members during each phase of the online platform development informed key decisions regarding the platform content, functionality, and the interface design to ensure it suited our target population. …”
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Oxytocin treatment at birth accelerates an epigenetic shift in the oxytocin receptor gene in the maternal brain by Allison M. Perkeybile, William M. Kenkel, Jason R. Yee, Rebecca E. Waugh, Travis S. Lillard, Craig F. Ferris, C. Sue Carter, Jessica J. Connelly

“…Conclusions Findings show epigenetic control of Oxtr is dynamic across pregnancy and birth and is sensitive to exogenous oxytocin. …”
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The phenology of Epilobium hirsutum L.: assessing marker compounds variability of a pharmaceutically important plant remedy by Olha Mykhailenko, Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Kateryna Uminska, Liudas Ivanauskas, Zigmantas Gudžinskas, Michael Heinrich, Michael Heinrich

“…Distinct seasonal patterns in the accumulation of β-hydroxycinnamic acids and ellagitannins provide insight into their physiological functions and potential pharmacological significance. …”
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An empirical study of the naïve REINFORCE algorithm for predictive maintenance by Rajesh Siraskar, Satish Kumar, Shruti Patil, Arunkumar Bongale, Ketan Kotecha, Ambarish Kulkarni

“…For the REINFORCE, a basic hyperparameter sensitivity and interaction analysis is conducted to better understand the dynamics and present results for the hyperparameters learning rate, discount factor $$\gamma$$ γ and the network activation functions (ReLU and Tanh). Our study suggests that, in the untuned state, simpler algorithms like the REINFORCE perform reasonably well. …”
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Effects of Different Processing Methods on the Quality Characteristics and Polyphenols Digestive Stability of Green Tea Noodles by Xiaoli MA, Yuan ZHANG, Xiaoxiu HUANG, Xiangbin CHU, Kun YU

“…This result could provide theoretical basis and application basis for improving the functional characteristics of green tea noodles.…”
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The multiple uses of artificial intelligence in exercise programs: a narrative review by Alberto Canzone, Alberto Canzone, Giacomo Belmonte, Antonino Patti, Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Fabio Rapisarda, Valerio Giustino, Patrik Drid, Antonino Bianco

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Extraction of <i>Suaeda salsa</i> from UAV Imagery Assisted by Adaptive Capture of Contextual Information by Ning Gao, Xinyuan Du, Min Yang, Xingtao Zhao, Erding Gao, Yixin Yang

“…This paper achieves the following research results: (1) An Adaptive Context Information Extraction module based on large kernel convolution and an attention mechanism is designed; this module functions as a multi-scale feature extractor without altering the spatial resolution, enabling a seamless integration into diverse network architectures to enhance the context-aware feature representation. (2) The proposed ACI-Unet (Adaptive Context Information U-Net) model achieves a high-precision identification of <i>Suaeda salsa</i> in UAV imagery, demonstrating a robust performance across heterogeneous morphologies, densities, and scales of <i>Suaeda salsa</i> populations. …”
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Role of Interleukins in Type 1 and Type 2 Diabetes by Roha Asif, Ammara Khalid, Tolga Mercantepe, Aleksandra Klisic, Sana Rafaqat, Saira Rafaqat, Filiz Mercantepe

“…<b>Objective</b>: This narrative review aims to provide a comprehensive and critical synthesis of current evidence on the role of key interleukins in T1D and T2D, highlighting their immunological functions, genetic associations, clinical correlations, and translational potential. …”
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