Exome analysis reveals species divergence in TYR and identifies species genetic markers in five endemic Macaca species on Sulawesi Island by Xiaochan Yan, Nami Arakawa, Kanthi Arum Widayati, Laurentia Henrieta Permita Sari Purba, Fahri Fahri, Bambang Suryobroto, Yohey Terai, Hiroo Imai

“…Additionally, it explores how these genetic differences influence biological functions, and identifies species-specific genetic markers for species identification and conservation. …”
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MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer by Yishan Huang, Ting Yang, Chen Yang, Bo Tang, Bo Su, Xiaojun Yang

“…The identification of differentially expressed genes (DEGs) and subsequent analyses, including signaling pathway enrichment, functional classification, and protein-protein interaction (PPI) network construction, were conducted using three public datasets: GSE32676, GSE71989, and GSE16515. …”
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Role of Fcγ receptors in HER2-targeted breast cancer therapy by Hope S Rugo, Antonino Musolino, William J Gradishar, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

“…This results in differential FcγR-mediated activities associated with differential therapeutic outcomes across multiple clinical settings, from early stage to metastatic disease, in patients with HER2+ breast cancer treated with the anti-HER2 mAb trastuzumab. …”
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Patterns and Associated Factors of Congenital Anomalies Among Neonates in 14 Yemeni Governorates 2021–2023: A Case: Control Study by Hiam Al-Atnah, Anas Al-Qubati, Amir Addin Al-Hashedi, Muath Al-Saidy, Saleh Al-Shawish, Moamer M. Badi, Najeeb Al-Qubati, Yasser Ghaleb, Maha Al-Muntaser

“…Background: Long-term disability and a reduced quality of life are often associated with congenital anomalies (CAs), which present as structural, functional, or metabolic defects. This study provides a comprehensive view of neonatal congenital anomalies in 14 Yemeni governorates, a significant but often overlooked public health concern. …”
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“It’s like going through life at a mediocre level”: a qualitative study of the meaning and impact of fatigue in children and young people with sickle cell disease by Brenda Agyeiwaa Poku, Karl Michael Atkin, John David Grainger, Iyamide Thomas, Rachael Oshinbolu, Abubakar Mohammed, Edith Kyewalyanga, Susan Kirk

“…Methods This exploratory research interviewed 12 CYP with SCD aged 12–23 years, five parents and ten healthcare professionals across England. Participants were recruited through convenience sampling from an NHS Trust, SCD-focused charities and social media. …”
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Histone H3 K4 trimethylation occurs mainly at the origins of polycistronic transcription in the genome of Leishmania infantum promastigotes and intracellular amastigotes by Aurora Diotallevi, Stefano Amatori, Giuseppe Persico, Gloria Buffi, Enrica Sordini, Marco Giorgio, Mirco Fanelli, Luca Galluzzi

“…These pathogens present unique mechanisms of gene expression characterized by functionally unrelated genes positioned in tandem and organized into polycistronic transcription units transcribed in a large pre-mRNA by RNA Polymerase II. …”
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GPU Acceleration for FHEW/TFHE Bootstrapping by Yu Xiao, Feng-Hao Liu, Yu-Te Ku, Ming-Chien Ho, Chih-Fan Hsu, Ming-Ching Chang, Shih-Hao Hung, Wei-Chao Chen

“…In summary, our accelerator offers improved efficiency, scalability, and flexibility for extensions, e.g., functional bootstrapping (Liu et al., Asiacrypt 2022), compared to current state-of-the-art solutions. …”
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Longitudinal Network Relationships Between Symptoms of Deviant Peer Affiliation and Internet Gaming Disorder in Adolescents: Prospective Cohort Study by Tingting Gao, Fengtong Qian, Rui Li, Yimeng Lyu, Yingying Su

“…Targeted interventions could disrupt the cycle of maladaptive behavior by focusing on improving both peer and social functioning during critical developmental periods, ultimately preventing the exacerbation of these behavioral issues over time.…”
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Migraine Headache and Its Related Disability Factors Among University Students in Jordan: A Cross-Sectional Study by Almomani MA, Almomani BA, Al-Sawalha NA, Alqudah AA

“…University students, especially, face psychological and academic stressors that may trigger migraine, leading to functional impairment. This can hinder concentration, studying, and academic performance, resulting in disability, reduced productivity, and absenteeism. …”
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Comprehensive review on co-integration of conventional systems and advanced oxidation processes for industrial and agricultural wastewater treatment applications by Lata Deso Abo, Mani Jayakumar, Albert Selvakumar Jeyapaul, Magesh Rangaraju, Hirpha Adugna Areti, Ayele Assefa Adugna

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Recent Advancements in Wearable Hydration-Monitoring Technologies: Scoping Review of Sensors, Trends, and Future Directions by Nazim A. Belabbaci, Raphael Anaadumba, Mohammad Arif Ul Alam

“…Commercially available products from 8 companies were also evaluated for their technological features, functionalities, and applications. The dominance of electrical sensors in research was highlighted due to their ease of use and integration into wearable devices. …”
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The Impact of Self-Management Interventions on Behavioral and Clinical Outcomes in Individuals with Systemic Lupus Erythematosus: A Systematic Review of Empirical Evidence From 200... by Hanrop S, Narupan N, Praha N, Phianhasin L, Ruksakulpiwat S

“…Self-management interventions led to significant improvements in physical health (eg, reduced fatigue and improved functional capacity), mental health (eg, reduced anxiety and depression), and health behaviors (eg, enhanced adherence to treatment and self-care practices). …”
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Tracking Upper Limb Motion via Wearable Solutions: Systematic Review of Research From 2011 to 2023 by Eirini Karoulla, Maria Matsangidou, Fotos Frangoudes, Panayiotis Paspalides, Kleanthis Neokleous, Constantinos S Pattichis

“…ObjectiveThe aim of this article is to investigate how wearables are used to capture upper limb functions, especially related to clinical and rehabilitation applications. …”
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Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker by Xiaojuan Yang, Xunjie Cao, Qing Zhu, Hong Wu

“…Abstract Gap junction protein B5 (GJB5, also known as Connexin 31.1) has recently been reported to be downregulated in several cancer types, where it functions primarily as a tumor suppressor in cancers such as melanoma and non-small cell lung cancer (NSCLC). …”
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Drug-eluting stents versus bare-metal stents for intracranial atherosclerotic stenosis: a systematic review and meta-analysis by Yan Ma, Liqun Jiao, Tao Wang, Bin Yang, Jie Wang, Jichang Luo, Renjie Yang, Wenlong Xu, Haozhi Gong

“…Subgroup analyses were conducted across different study types.Results A total of 510 participants fulfilling all eligibility criteria were enrolled in four studies. …”
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Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study. by Jeannette Simino, Zhiying Wang, Jan Bressler, Vincent Chouraki, Qiong Yang, Steven G Younkin, Sudha Seshadri, Myriam Fornage, Eric Boerwinkle, Thomas H Mosley

“…Plasma aβ concentrations may have dynamic biological determinants across the lifespan; plasma aβ study designs or analyses must consider age.…”
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Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction by Fang Lyu, Yuxin Zhong, Qingliu He, Wen Xiao, Xiaoping Zhang

“…Gene expression was confirmed in ccRCC cell lines (786-O, Caki-1) and tumor tissues. Functional assays, such as wound healing and Transwell assays, were employed to evaluate tumor invasion and migration. …”
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Telepharmacy for outpatients with cancer: An implementation evaluation of videoconsults compared to telephone consults using the CFIR 2.0 by Marissa Ryan, Elizabeth C. Ward, Clare Burns, Christine Carrington, Katharine Cuff, Mhairi Mackinnon, Centaine L. Snoswell

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Effectiveness of horizontal posts to support MOD cavities compared with other restorative approaches in endodontically treated teeth: systematic review with meta-analysis of labora... by Mohammed Ahmed Alghauli, Ahmed Yaseen Alqutaibi, Redhwan Saleh Al-Gabri, Abdulmajeed Abdulaziz Baik, Anas Mazen Mahrous, Arwa Bafail, Samah Saker

“…Methods A comprehensive search was conducted in December 2024 across various databases, including PubMed, Scopus, Web of Science, and Google Scholar. …”
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Longitudinal changes of resting-state networks in Parkinson‘s disease by Matthias Sure, Rasha Hyder, Levent Kandemir, Jan Vesper, Alfons Schnitzler, Esther Florin

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