Genetic determinants of circulating sphingolipid concentrations in European populations. by Andrew A Hicks, Peter P Pramstaller, Asa Johansson, Veronique Vitart, Igor Rudan, Peter Ugocsai, Yurii Aulchenko, Christopher S Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A Cecilej W Janssens, Anatoly V Kirichenko, Inke R König, Fabio Marroni, Ozren Polasek, Ayse Demirkan, Ivana Kolcic, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C M Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I Axenovich, Annette Peters, Stefan Schreiber, H-Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A Oostra, Sarah H Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M van Duijn, James F Wilson, Alan Wright, Gerd Schmitz, Harry Campbell

“…An additional 70 variants across 23 candidate genes involved in sphingolipid-metabolizing pathways also demonstrate association (p = 10(-4) or less). …”
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Effectiveness and cost-effectiveness of a web-based routine assessment with integrated recommendations for action for depression and anxiety (RehaCAT+): protocol for a cluster rand... by Reinhold Kilian, Harald Baumeister, Yannik Terhorst, Johannes Knauer, Paula Philippi, Selina Kallinger, Sandro Eiler, Tamara Waldmann, Morten Moshagen, Martina Bader

“…A total sample of 1848 participants will be recruited across all clinics. The primary outcome, depression severity at 12 months follow-up (T3), will be assessed using the CAT Patient-Reported Outcome Measurement Information System Emotional Distress-Depression Item set. …”
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The Effect of a Manni Telescopic Herbst Appliance with Four Miniscrews (STM4) on the Treatment of a Class II Division I Malocclusion: A 3D Finite Element Study by Andrea Boggio, Abdolreza Jamilian, Antonio Manni, Giorgio Gastaldi, Rosana Farjaminejad, Mojtaba Hasani, Mauro Cozzani

“…FEA analyzed displacement across dentoalveolar structures along the X, Y, and Z axes to assess treatment efficacy and biomechanical stability. …”
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Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…The radius of gyration (Rg) results indicated a consistent value of ~15.3 Å across systems, confirming the role of SG-A in maintaining protein integrity. …”
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Comparative analysis of ground reaction forces and spatiotemporal gait parameters in older adults with sway-back posture and chronic low back pain: a cross-sectional study by Fatemeh Esmaeilpour, Amir Letafatkar, Mohammad Taghi Karimi, Mehdi Khaleghi, Giacomo Rossettini, Jorge Hugo Villafañe

“…Abstract Background Gait alterations associated with postural deviations are a significant factor contributing to functional limitations in older adults. Among these, sway-back posture has been linked to chronic low back pain (CLBP), defined as pain persisting for more than three months. …”
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Attitude of Healthcare Providers Towards Care of People with Disabilities, in Hail Region, Saudi Arabia by Saleh KA, Alrubaiee GG, Alqalah TAH, Almoliky MA, Alrashedi H, Alkubati SA, Ahmed WA

“…The data were collected through an online survey and analyzed using SPSS 26.Results: The results indicated a generally positive attitude of healthcare providers towards people with disabilities, with mean scores exceeding 89 across various groups. Older providers (over 35 years old) exhibited the highest positivity rate (92.57), although differences in age, sex, educational level, years of experience, and professional role were not statistically significant. …”
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Biochar-based organic substrates enhance tomato growth by promoting specific microbial communities in rooftop farming by Miguel de Celis, Laura L. de Sosa, Giuseppe Picca, Noelia González-Polo, Cristina Gómez Ruano, Luciano Beneduce, Claudio Zaccone, Marco Panettieri

“…Even though alternative substrates presented higher bacterial diversity than peat, the taxonomic composition was similar across alternative substrates, reflecting the functional redundancy of the bacterial communities. …”
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Genome Selection and Genome-Wide Association Analyses for Litter Size Traits in Large White Pigs by Yifeng Hong, Xiaoyan He, Dan Wu, Jian Ye, Yuxing Zhang, Zhenfang Wu, Cheng Tan

“…Furthermore, a single-step genome-wide association study (ssGWAS) integrated genomic information and pedigree-based relationship matrices to screen for significant SNPs associated with litter size traits across the genome. Functional analysis of key candidate genes was subsequently conducted based on ssGWAS results. (3) Results: Heritabilities for litter traits ranged from 0.01 to 0.06. ssGBLUP improved genomic prediction accuracy by 6.38–13.33% over BLUP. …”
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Mental health literacy among Jordanian nurses: a cross-sectional study and scale validation by Walid Al-Qerem, Anan Jarab, Judith Eberhardt, Fawaz Alasmari, Alaa Hammad, Amani Moh’d Ibrahim Alfarajat, Sarah Abu Hour, Lujain Al-sa’di, Rama AlKhateeb, Walaa Ashran

“…Rasch analysis confirmed proper item hierarchy and no significant gender-based differential item functioning. Cronbach’s α values exceeded 0.70 across all factors, supporting the scale’s reliability. …”
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Oral history methods can reveal drivers of landscape transformation: Understanding land‐use legacies with local and traditional knowledge in Central Europe by Marianna Biró, Krisztina Molnár, Kinga Öllerer, Réka Szilágyi, Dániel Babai, Csaba Molnár, Zsolt Molnár

“…By creating knowledge partnerships, we can still learn about the past management and the functioning of such biodiversity‐rich cultural landscapes from the people who actively maintained them. …”
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A theory-based analysis of the implementation of online asynchronous telemedicine platforms into primary care practices using Normalisation Process Theory by Cara Leighton, Natalie Joseph-Williams, Annavittoria Porter, Adrian Edwards, Alison Cooper

“…Widespread implementation of online platforms in primary care practices can be supported by policy-makers through consistent guidelines to improve platforms’ content, functionality and compatibility with clinical systems to try to enable improvements in practice. …”
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Identification and expression analysis of PAL genes related to chlorogenic acid synthesis in Vaccinium dunalianum Wight by Xiuhua An, Guoze Li, Aiyi Chen, Ping Zhao, Yong Ding

“…The PAL gene family mediates the biosynthesis of CGA in V. dunalianum, with the combined expression of VdPAL1/2/4/5/6/7 showing a positive correlation with the CGA content across the analyzed tissues. These results provide experimental evidence for understanding the composition, structural characteristics, and biological functions of the PAL genes in V. dunalianum.…”
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Workload and salary as determinants of pedagogical graduates’ employment by occupation by L. M. Nurieva, S. G. Kiselev

“…The slices were studied in detail using the Analysis ToolPak addin procedures and the statistical functions of the Excel library. In the course of the analysis, the authors performed the calculation of measures of the statistical relationship between the studied variables and their graphic visualisation.Results. …”
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Tyrosine kinase inhibitor, masitinib, limits neuronal damage, as measured by serum neurofilament light chain concentration in a model of neuroimmune-driven neurodegenerative diseas... by Olivier Hermine, Laurent Gros, Truong-An Tran, Lamya Loussaief, Kathleen Flosseau, Alain Moussy, Colin D Mansfield, Patrick Vermersch

“…A beneficial effect of masitinib on functional performance was also observed, with both M50 and M100 groups showing significantly less relative deterioration in grip strength at day-15 as compared with control (p < 0.001).…”
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The potential of glutamine supplementation in reduced-crude protein diets for chicken-meat production by Peter H. Selle, Shemil P. Macelline, Mehdi Toghyani, Sonia Yun Liu

“…On balance, the outcomes were positive, but the average dietary CP was 213 g/kg across the twenty feeding studies, which indicates that CP and, in turn, glutamine concentrations would have been adequate. …”
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Harnessing Research Pressure: A Dual Chain Mediation Effects of Achievement Motivation and Research Anxiety on Innovative Behavior Under Challenge-Hindrance Research Stressors by Ma J, Hu L

“…Notably, we identify that achievement motivation both mitigates anxiety and functions as a chain mediator linking stressors to innovative outcomes. …”
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Cradle-to-gate life cycle assessment of hemp utilization for biocomposite pellet production: A case study with data quality assurance process by Niloofar Akbarian-Saravi, Taraneh Sowlati, Abbas S. Milani

“…Namely, an attributional Life Cycle Assessment (LCA) is performed using a functional unit of 1 tonne of biocomposite, comparing four Supply Chain (SC) design alternatives involving different baler (round/square) and size reduction equipment (full/half screen hammer mill) options. …”
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394 Inclusion of cytomegalovirus viral Fc gamma receptors in a glycoprotein B protein subunit vaccine improves Fc-mediated effector responses by Claire Otero, Mackensie Gross, Savannah Herbek, Megan Connors, Philipp Kolb, Sallie Permar

“…This effect was maintained across several human CMV strains with variable vFcγR genes. …”
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Impact of body-positive social media content on body image perception by Ana Maria Jiménez-García, Natalia Arias, Elena Picazo Hontanaya, Ana Sanz, Olivia García-Velasco

“…Methods A systematic review and meta-analysis were conducted following PRISMA guidelines, analyzing studies published until 2024 across PubMed, Scopus, ScienceDirect, and Web of Science. …”
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Polyaniline nano-material backed lens antenna for X-band LEO satellite transceivers by H. Abuklill, Khalid F. A. Hussein, A. A. Shaalan, Mohamed E. Nasr, A. M. Elshaer

“…The axial ratio remains below 3 dB across the working sector at the center frequency of 10 GHz, while the input reflection coefficient stays better than − 10 dB over a wide impedance matching bandwidth of 8.75–11.25 GHz. …”
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