FEATURES OF FUNCTIONALITY OF CARDIOVASCULAR SYSTEM OF UNIVERSITY STUDENTS, LIVING IN THE INDUSTRIAL CITIES OF EASTERN SIBERIA by O. Yu. Katulskaya

“…In the present study we used physiological research methods, including the assessment of the functional state of the cardiovascular system, taking into account the reactions to physical exercise and evaluation of adaptive capacity with the calculation of the index of functional changes (1F1) by R.M. …”
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Integrated transcriptomic and functional modeling reveals AKT and mTOR synergy in colorectal cancer by Marcin Duleba, Eliza Zimoląg, Joanna Szuszkiewicz, Marcin Serocki, Joanna Szklarczyk, Olga Dracz, Alexander Kurzejamski, Izabella Więckowska, Marcelina Chmiel, Barbara Lipert, Katarzyna Sarad, Joanna Krawczyk, Oleksii Bryzghalov, Agata Stachowicz-Wałaszek, Karolina Pyziak, Joanna Drozdowska, Krzysztof Baczyński, Konrad Wojtowicz, Maurycy Chronowski, Krzysztof Rataj, Magdalena Otrocka, Michał Mikula, Paula Feliksiak, Rafał Dziadziuszko, Tomasz Rzymski, Andrew Thomason, Krzysztof Brzózka, Andrzej Mazan

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Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes by Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Denise Bei Lin Teo, Ka-Wai Cheung, Chin Ren Goh, Faris Kairi, Elizabeth Lee, Francesca Lorraine Wei Inng Lim, Michaela Su-Fern Seng, Shui Yen Soh, Michael E. Birnbaum, Jongyoon Han

“…Here, we introduce the Cell Trajectory Modulation (CTM) assay, a microfluidic, label-free approach for the rapid evaluation of the functional attributes of CAR T cells based on biophysical features (i.e., size, deformability). …”
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Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies. by Saeid Alinezhad, Riina-Minna Väänänen, Jesse Mattsson, Yifeng Li, Terhi Tallgrén, Natalia Tong Ochoa, Anders Bjartell, Malin Åkerfelt, Pekka Taimen, Peter J Boström, Kim Pettersson, Matthias Nees

“…However, only few predictive markers identified in silico have also been validated for clinical, functional or mechanistic relevance in disease progression. …”
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A robust method for assessing mitochondrial function in healthy and diseased frozen cardiac tissue by Liangyu Hu, Alexia van Rinsum, Rocco Caliandro, Xi Qi, Shuxiu Fan, Xinyi Jiang, Jur Massop, Melissa Bekkenkamp-Grovenstein, Christiane Ott, Tilman Grune, Melissa A. E. van de Wal, Werner J. H. Koopman, Marcel Giesbers, Monika Gladka, Jaap Keijer, Deli Zhang

“…Abstract Cardiovascular diseases are often associated with impairment in mitochondrial function. However, existing respirometry measuring mitochondrial function are limited by the necessity of fresh tissue samples. …”
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Bacterial community function increases leaf growth in a pitcher plant experimental system by Jessica R. Bernardin, Erica B. Young, Sarah M. Gray, Leonora S. Bittleston

“…ABSTRACT Across diverse ecosystems, bacteria and their hosts engage in complex relationships having negative, neutral, or positive interactions. …”
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Pupillographic evaluation accompanying structural and functional assessment of the optic nerve in patients with Parkinson’s disease by Erdinç Bozkurt, Ersin Muhafız, Can Emre Erdoğan, Şerif Nizamoğulları, Güvenç Toprak, Bayram Meydan

“…Abstract Background To evaluate static and dynamic pupillary functions, contrast sensitivity, and retinal nerve fiber layer (RNFL) thickness in patients with Parkinson’s disease. …”
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Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes by Jody Dushay, Eva S. Rickers, Enya Wang, Jessica Gilman, Ying Zhang, Ron Blankstein, Ernest V. Gervino, Michael Jerosch‐Herold, Aristidis Veves

“…This study evaluates the impact of inflammation and sex differences on coronary and peripheral vascular function and exercise capacity in older individuals with and without T2D. …”
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Long-Term Impact of Recurrent Acute Otitis Media on Balance and Vestibular Function in Children by Mirko Aldè, Pietro Bosi, Stefanie Muck, Thomas Mayr, Paola Di Mauro, Valentina Berto, Beatrice Gaia Aleandri, Francesco Folino, Stefania Barozzi, Diego Zanetti, Paola Marchisio

“…Static posturography was used to assess postural instability, measuring sway area (SX, mm²) under four conditions: eyes open and eyes closed, with and without foam pads. Vestibular function was evaluated using the video head impulse test (v-HIT) to quantify vestibulo–ocular reflex (VOR) gain and corrective saccades across all six semicircular canals. …”
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Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian by Masa Petrovic, Bojana Salovic, Ana Tomic, Tanja Jesic-Petrovic, Aleksandar Matejic, Ivana Radovic, Silvana Babic, Aleksa Korugic, Drago Jelovac, Nikola Mikovic, Sasa Jakovljevic, Svetislav Pelemis, Milovan Dimitrijevic, Jovica Milovanovic, Ana Jotic, Aleksandar Trivic, Ana Dimitrijevic, Sulin Bulatovic, Zoran Dudvarski, Ivan Soldatovic, Jelena Ilic-Zivojinovic

“…Abstract This study aimed to translate and validate the Functional Assessment of Cancer Therapy – Head & Neck (FACT-HN) in a Serbian-speaking population, assessing its psychometric properties and utility in evaluating the quality of life in head and neck cancer patients. …”
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DetectEV: A functional enzymatic assay to assess integrity and bioactivity of extracellular vesicles by Giorgia Adamo, Sabrina Picciotto, Paola Gargano, Angela Paterna, Samuele Raccosta, Estella Rao, Daniele Paolo Romancino, Giulio Ghersi, Mauro Manno, Monica Salamone, Antonella Bongiovanni

“…Given the inherent heterogeneity in EV preparations, this assessment demands sensitive functional assays to provide key quality control metrics, complementing established methods to ensure that EV preparations meet the required functionality and quality standards. …”
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Early functional changes in lewy body dementia: roles of dynamics, locus coeruleus, and compensation by Kristína Mitterová, Eva Výtvarová, Anežka Kovářová, Martin Lamoš, Jan Fousek, Irena Rektorová

“…We observed a nonlinear trajectory of two functional connectivity metrics—temporal variability (fluidity) and connectedness (average node strength)—across symptom severity, especially in the delta frequency band. …”
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Importance of the actual plant height in modulating the within-community spectrum of plant form and function by Dong He, En-Rong Yan, En-Rong Yan, Li-Ting Zheng, Yan-Jun Song, Xiao-Dong Yang, Wen-Hui You, J. Hans C. Cornelissen

“…Maximum height (Hmax) is a principal driver or correlate of interspecific variation in many plant functional traits. Still, it remains unclear why leaf resource economic traits are invariant with Hmax at global scale and why broad-scale interspecific trait correlations are not retained at local scale. …”
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Loss of Hoxa5 function affects Hox gene expression in different biological contexts by Béatrice Frenette, Josselin Guéno, Nicolas Houde, Kim Landry-Truchon, Anthony Giguère, Theyjasvi Ashok, Abigail Ryckman, Brian R. Morton, Jennifer H. Mansfield, Lucie Jeannotte

“…We applied bulk RNA-seq assays to characterize the transcriptional impact of the loss of Hoxa5 gene function in seven different biological contexts, including developing respiratory and musculoskeletal tissues that present phenotypes in Hoxa5 mouse mutants. …”
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Analysis of diagnostic decision in acupuncture from the actual functional dyspepsia patient's clinical information by Song-Yi Kim, San Hwa Hong, Jae-Woo Park, Hyangsook Lee, Jaeyoung Kim, Yangseok Kim, You-Sang Baik, Seok-Jae Ko, Seul-Ki Kim, In-Seon Lee, Younbyoung Chae, Hi-Joon Park

“…Conclusion: There are common acupoints across different patterns, but pattern-specific acupoints were also recommended. …”
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Leaf functional traits highlight phenotypic variation of two tree species in the urban environment by Ahram Cho, Nicole Dziedzic, Aria Davis, Cindy Hanson, Jangho Lee, Gabriela C. Nunez-Mir, Miquel A. Gonzalez-Meler

“…Urbanization is transforming landscapes globally, altering environmental conditions that affect ecosystem functioning, particularly in urban areas where trees are crucial for regulating microclimates, improving air quality, and sustaining biodiversity. …”
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Functional diversity of benthic macroinvertebrates and fluvial habitat quality: Key biological trait categories by Gonzalo Sotomayor, Henrietta Hampel, Raúl F. Vázquez, Marie Anne Eurie Forio, Peter L.M. Goethals

“…Functional diversity (FD) calculations using benthic macroinvertebrates are useful for freshwater ecosystem evaluation. …”
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Applications and advances of combined fMRI-fNIRs techniques in brain functional research by Lirui Yang, Lirui Yang, Lirui Yang, Lirui Yang, Zehua Wang, Zehua Wang, Zehua Wang, Zehua Wang, Zehua Wang

“…Understanding the intricate functions of the human brain requires multimodal approaches that integrate complementary neuroimaging techniques. …”
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ProQuest Ebook Platform Outperforms EBSCO Ebook Platform in Functionality and Usability Study by Kristy Hancock

“…Main Results – The ProQuest and EBSCO user interfaces have similar functionality. Users can search across the platform and within an ebook, view digital rights and bibliographic information, and access the full-text of a book. …”
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Evaluating Mathematical Concordance Between Taxonomic and Functional Diversity Metrics in Benthic Macroinvertebrate Communities by Gonzalo Sotomayor, Henrietta Hampel, Raúl F. Vázquez, Christine Van der heyden, Marie Anne Eurie Forio, Peter L. M. Goethals

“…Macroinvertebrate communities were sampled over six years at twelve sampling points and assessed using four taxonomic metrics: Shannon diversity (H), the Margalef index (D_Mg), family richness (N), and the Andean Biotic Index (ABI). Functional diversity was evaluated using four metrics: weighted functional dendrogram-based diversity (wFDc), Rao’s quadratic entropy (Rao), functional dispersion (FDis), and functional richness (FRic). …”
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