Comparative Genomics of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> Reveals Strain-Level Hyperdiversity, Carbohydrate Metabolism Adaptations, and CRISPR-Mediated Phage Imm... by Ozge Can, Ismail Gumustop, Ibrahim Genel, Hulya Unver, Enes Dertli, Ibrahim Cagri Kurt, Fatih Ortakci

“…Our findings enhance our understanding of the genetic and functional diversity of <i>B. animalis</i> subsp. <i>lactis</i>, providing valuable insights for its use in probiotics and functional foods.…”
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The role of affective touch in mental illness: a systematic review of CT fiber dysregulation in psychological disorders and the therapeutic potential of CT fiber stimulation by Martina Papi, Davide Decandia, Daniela Laricchiuta, Debora Cutuli, Debora Cutuli, Livia Buratta, Maurizio Peciccia, Claudia Mazzeschi

“…IntroductionOver the past few decades, research on affective touch has clarified its impact on key psychological functions essential for environmental adaptation, such as self-awareness, self-other differentiation, attachment, and stress response. …”
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Patterns of time spent in sedentary behavior, physical activity, and sleep are associated with cognitive decline among CLSA participants: A latent class analysis by R.A. Palazuelos-González, R.C. Oude-Voshaar, N. Smidt, A.C. Liefbroer

“…The SedDS group showed greater cognitive decline after 3 year follow-up across all cognitive domains (memory β = −0.061, 95%CI −0.100, −0.021; executive functioning β = −0.049, 95%CI −0.090, −0.008; overall cognition β = −0.067, 95%CI −0.106, −0.027) compared to IntNS. …”
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Beyond the interface: benchmarking pediatric mobile health applications for monitoring child growth using the Mobile App Rating Scale by Anggi Septia Irawan, Arie Dwi Alristina, Arie Dwi Alristina, Rizky Dzariyani Laili, Nuke Amalia, Arief Purnama Muharram, Adriana Viola Miranda, Bence Döbrössy, Edmond Girasek

“…Quality assessment found significant variability across the apps, with high functionality and aesthetics scores but more variability in the domains of app engagement, quality of information, and subjective quality or perceived value.ConclusionThis research underscored the need for the development of higher-quality, evidence-based mHealth apps for pediatric care in Indonesia, particularly in improving user engagement, feedback mechanisms and accessibility.…”
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A Vignette Study to Derive Health-Related Quality-of-Life Weights for Individuals with Steroid Refractory Chronic Graft-versus-Host Disease Receiving Third-Line Therapy in the Unit... by Emma Williams, Luke Skinner, Richard Hudson, Arunesh Sil, Katharina Ecsy, Elisheva Lew, Abdul Jabbar Omar Alsaleh, Elin Gruffydd, Andrew Lloyd, Daniele Avenoso

“… # Conclusion This study generated utility values for HS vignettes describing symptoms, functioning, and HRQoL for patients with cGvHD receiving 3L therapy. …”
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Outcomes after ulnar collateral ligament injuries in non-throwing athletes: a systematic review by Benjamin Miltenberg, MD, William L. Johns, MD, Anthony N. Baumann, DPT, MD, Brandon J. Martinazzi, MD, Omkar Anaspure, BA, Terence L. Thomas, MD, Michael G. Ciccotti, MD, Steven B. Cohen, MD

“…Eleven sports were represented across four levels of competition from middle school to the professional level. …”
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Exploring NUP62’s role in cancer progression, tumor immunity, and treatment response: insights from multi-omics analysis by Lihong Chen, Youfu He, Menghui Duan, Tianwen Yang, Yin Chen, Bo Wang, Dejun Cui, Chen Li

“…BackgroundNUP62, a key component of the nuclear pore complex, is closely associated with cellular functions and cancer progression. However, its expression patterns, prognostic value, and relationship with tumour immunity and drug sensitivity across multiple cancers have not been systematically studied. …”
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Single-cell characterization of the immune heterogeneity of pulmonary hypertension identifies novel targets for immunotherapy by Pan Jiang, Huai Huang, Mengshi Xie, Zilong Liu, Lijing Jiang, Hongyu Shi, Xiaodan Wu, Shengyu Hao, Shanqun Li

“…Significant changes and potential functions of myeloid cell subsets in PAH patients and we especially focused on GPNMB+ macrophages. …”
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Non-Targeted Lipidomics Analysis of Characteristic Milk Using High-Resolution Mass Spectrometry (UHPLC-HRMS) by Tingting Wei, Tianxiao Zhou, Shenping Zhang, Zhexue Quan, Yang Liu

“…This study offers a comprehensive lipidomic landscape across diverse milk sources, providing molecular insights to guide the development of tailored, functional, and regionally branded dairy products.…”
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Genome-wide identification and expression pattern analysis of the cinnamoyl-CoA reductase gene family in flax (Linum usitatissimum L.) by Xixia Song, Dandan Liu, Yubo Yao, Lili Tang, Lili Cheng, Lie Yang, Zhongjuan Jiang, Qinghua Kang, Si Chen, Jiarong Ru, Lili Zhang, Guangwen Wu, Hongmei Yuan

“…Furthermore, each of these LuCCRs is encoded by 5 exons separated by 4 introns, a characteristic feature of functional CCRs. Phylogenetic analysis grouped LuCCRs into two clades, with LuCCR7/13/15/20 clustering with functional CCRs involved in LB in dicotyledonous plants. …”
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Corticobulbar activity in healthy humans and Parkinson’s disease: a study protocol for a novel biomarker of motivational arousal by Francesca Ferraioli, Francesco Tomaiuolo, Alessandra M. Falzone, Angelo Labate, Salvatore M. Cardali, Simona Massimino, Fabrizio Esposito, Antonino Germanò, Luigi Trojano, Carmelo Mario Vicario

“…Findings may contribute to identifying non-invasive biomarkers of motivational functioning in both clinical and normative populations.…”
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De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</... by Mengling Wen, Junlan Zeng, Fei Qiu, Fangyuan Zhang, Zhihua Liao

“…In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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Novel Acylated Naringin Enhances Propionate Release and Stimulates the Growth of Flavanone-Metabolizing Bacteria in an In Vitro Batch Fermentation Model by Blanca Elizabeth Ruiz-Álvarez, José Daniel Padilla-de la Rosa, Marisela González Avila, Georgina Sandoval, Yves Desjardins

“…These preliminary results highlight the potential of SCFA-acylated flavonoids as functional dietary components to increase SCFA bioavailability and support gut health, particularly from citrus-derived co-products.…”
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Surface Charge Transfer Enhanced Cobalt‐Phthalocyanine Crystals for Efficient CO2‐to‐CO Electroreduction with Large Current Density Exceeding 1000 mA cm−2 by Tengyi Liu, Di Zhang, Yutaro Hirai, Koju Ito, Kosuke Ishibashi, Naoto Todoroki, Yasutaka Matsuo, Junya Yoshida, Shimpei Ono, Hao Li, Hiroshi Yabu

“…The resulting CoPc/CP electrode maintains > 90% CO selectivity across a broad ECR window (−0.57 to −1.32 V vs RHE), achieves a record‐breaking CO current density of −1034 mA cm−2, an ultrahigh mass activity of 5180 A g−1, and demonstrates excellent long‐term stability (145 h @ −150 mA cm−2), surpassing all reported Pc‐based catalysts. …”
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Identification and Analysis of Circular RNAs in Mammary Gland from Yaks Between Lactation and Dry Period by Yilin Shi, Xiaoyun Wu, Guangyao Meng, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Ping Yan

“…The host genes of these DECs were enriched in functions and pathways associated with yak milk synthesis and composition. …”
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The Effect of Physiotherapy on Arthrogenic Muscle Inhibition After ACL Injury or Reconstruction: A Systematic Review by Maria Paço, Maxence Peysson, Elona Dumont, Mário Correia, Anna Quialheiro, Paula Chaves

“…Vibration showed inconsistent results across three studies. Methodological quality varied between 5 and 8 on the PEDro scale, with moderate-to-low risk of bias. …”
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Combined effects of acidification and warming on soil denitrification and microbial community by Peiyuan Xu, Peiyuan Xu, Mengke Gao, Mengke Gao, Yuchen Li, Yuchen Li, Jun Ye, Jianqiang Su, Jianqiang Su, Hu Li, Hu Li

“…In light of the challenges posed by contemporary global warming and soil acidification, the respective effects of pH and temperature on soil microbiome and functions have been explored. However, the combined influence of acidification and warming on soil denitrification and active microbial communities are still unclear. …”
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Exploring the therapeutic and nutritional potential of camel milk: Challenges and prospects: A comprehensive review by Soumya Singh, Sonia Mann, Rhythm Kalsi, Shambhavi Singh, Neetu Kumra Taneja, Harinder Singh Oberoi, Komal Chauhan, Pankaj Taneja

“…Camel milk, often termed ''white gold,'' is an essential nutritional resource for nomadic communities in arid regions, particularly across East and Central Africa. Known for its high levels of vitamins, minerals, proteins, and bioactive compounds, camel milk has gained attention for both its nutritional and therapeutic potential. …”
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Cresyl diphenyl phosphate (a novel organophosphate ester) induces hepatic steatosis by directly binding to liver X receptor α: From molecule action to risk assessment by Xinya Liu, Lanchao Sun, Yongfeng Lin, Jingyue Du, Huizi Yang, Chuanhai Li

“…In this work, we investigated CDP-induced hepatic steatosis through Liver X Receptor α (LXRα) pathway across the molecular interactions, signaling pathways, cell functions, animal effects, and population risks, and compared them to triphenyl phosphate (TPHP) and tricresyl phosphate (TCRP). …”
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Allochrony in Atlantic Lumpfish: Genomic and Otolith Shape Divergence Between Spring and Autumn Spawners by Mathilde Horaud, Núria Raventós, Kim Præbel, Carles Galià‐Camps, Cinta Pegueroles, Carlos Carreras, Marta Pascual, Victor M. Tuset, Shripathi Bhat, Arve Lynghammar

“…The presence of genomic islands of divergence, alongside a general lack of differentiation across the mitochondrial genome, suggest recent and rapid selection processes potentially modulated by ongoing gene flow. …”
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