Varying association of laboratory values with reference ranges and outcomes in critically ill patients: an analysis of data from five databases in four countries across Asia, Europ... by Xiaoli Liu, Leo Anthony Celi, Haoran Xu, Louis Agha-Mir-Salim, Zachary O’Brien, Dora C Huang, Peiyao Li, Josep Gómez, Tongbo Liu, Wesley Yeung, Patrick Thoral, Paul Elbers, Zhengbo Zhang, María Bodí Saera

“…Kernel density estimation functions were applied to the distributions of laboratory tests, and the overlapping coefficient and Cohen standardised mean difference were used to quantify differences in these distributions.Results The 259 382 patients studied across five databases in four countries showed a high degree of heterogeneity with regard to demographics, case mix, interventions and outcomes. …”
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The balance evaluation systems test (BESTest), mini-BESTest and brief-BESTest as clinical tools to assess balance control across different populations: A reliability generalization... by Ana-Belén Meseguer-Henarejos, Juan-José López-García, José-Antonio López-Pina, Ignacio Martínez-González-Moro, Ángel Martínez-Carrasco

“…<h4>Background</h4>The Balance Evaluation Systems Test (BESTest) and two abbreviated versions, Mini-BESTest and Brief-BESTest are used to assess functioning of balance control systems. Its reliability across different populations remains to be determined.…”
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Evolutionary Dynamics and Functional Bifurcation of the C2H2 Gene Family in Basidiomycota by Chao Duan, Jie Yang

“…This study performed a phylogenomic analysis of the C2H2 gene family across 30 Basidiomycota species, identifying 1032 genes distributed across six evolutionary clades (Groups I–VI). …”
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Pan-genome-scale metabolic modeling of Bacillus subtilis reveals functionally distinct groups by Maxwell Neal, William Brakewood, Michael Betenbaugh, Karsten Zengler

“…These models encapsulate the totality of metabolic functions for a given organism. Bacillus subtilis strain 168 is one of the first bacteria for which a metabolic network was reconstructed. …”
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A Surrogate Piecewise Linear Loss Function for Contextual Stochastic Linear Programs in Transport by Qi Hong, Mo Jia, Xuecheng Tian, Zhiyuan Liu, Shuaian Wang

“…Experiments across multiple machine learning models demonstrate consistent improvements in decision quality, with neural networks showing the most significant gains—improving decision outcomes in 36 out of 45 cases. …”
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Multi-omics analysis reveals the evolution, function, and regulatory mechanisms of SPF pheromones in Anurans by Puyang Zheng, Yunyun Lv, Yuzhou Gong, Gang Wang, Bin Wang, Xiuqin Lin, Xun Liao, Jianghong Ran, JiaTang Li, Feng Xie

“…Abstract Pheromones play a pivotal role in chemical communication across various taxa, with protein-based pheromones being particularly significant in amphibian courtship and reproduction. …”
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Using large language models to extract plant functional traits from unstructured text by Viktor Domazetoski, Holger Kreft, Helena Bestova, Philipp Wieder, Radoslav Koynov, Alireza Zarei, Patrick Weigelt

“…The question‐answering model yielded a normalized mean absolute error of 10.3% averaged across three numerical traits. Discussion The natural language processing pipeline we propose has the potential to facilitate the digitization and extraction of large amounts of plant functional trait information residing in scattered textual descriptions.…”
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Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies. by Christian O'Reilly, John D Lewis, Mayada Elsabbagh

“…Further investigation is, however, needed to corroborate the conclusion and its generalizability across different tasks. Of note, abnormal lateralization in ASD, specifically an elevated left-over-right EEG and MEG functional connectivity ratio, has been also reported consistently across studies.…”
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Socioeconomic inequalities in physical function decline: multilevel longitudinal results from the HABITAT study by Jerome N Rachele, Venurs Loh, Anna Timperio, Jenny Veitch, Rees Thomas, Rebecca A Reid, Wendy J Brown

“…Conclusion There was little evidence of inequalities in the magnitude of decline in physical function across socioeconomic groups between the two time points. …”
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Hurricanes lead to declines in taxonomic, phylogenetic, and functional richness and shifts in moth community composition by Aura M. Alonso‐Rodríguez, Pablo E. Gutiérrez‐Fonseca, Ingi Agnarsson, Catherine M. Hulshof, Scott E. Miller, Taylor H. Ricketts

“…Our findings show that hurricane disturbance reduced species richness across all diversity dimensions, while functional diversity among dominant species increased, suggesting potential stabilization of ecosystem functions despite reduced richness. …”
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TIMM23 overexpression drives NSCLC cell growth and survival by enhancing mitochondrial function by Jianhua Zha, Jiaxin Li, Hui Yin, Mingjing Shen, Yingchen Xia

“…Moreover, TIMM23 expression was consistently elevated across multiple primary/established NSCLC cells. Silencing or ablation of TIMM23 via shRNA or CRISPR/Cas9 in NSCLC cells resulted in impaired mitochondrial function, characterized by reduced complex I activity, ATP depletion, mitochondrial membrane potential dissipation, oxidative stress, and lipid peroxidation. …”
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Haplotype-resolved genomes provide insights into the origins and functional significance of genome diversity in bivalves by Shikai Liu, Chenyu Shi, Chenguang Chen, Ying Tan, Yuan Tian, Daniel J. Macqueen, Qi Li

“…Comparisons of haplotype-resolved genomes across four bivalve orders uncover diverse HDS origins, highlighting a role in genetic innovation and expression regulation across broad timescales. …”
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Aptamer-Functionalized Gold Nanoparticle Assay for Rapid Visual Detection of Norovirus in Stool Samples by Maytawan Thanunchai, Sirikwan Sangboonruang, Natthawat Semakul, Kattareeya Kumthip, Niwat Maneekarn, Khajornsak Tragoolpua

“…Norovirus (NoV), a leading cause of acute gastroenteritis worldwide, imposes significant morbidity and economic burdens across all age groups. Timely and accurate laboratory diagnosis is crucial for effective outbreak control and patient management. …”
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The effects of physical exercise on cognitive function in adolescents: a systematic review and meta-analysis by Longyan Liu, Xianyang Xin, Ying Zhang

“…This systematic review and meta-analysis primarily aimed to determine the overall impact of physical exercise interventions on adolescent cognitive function. It also extended to explore effects on specific cognitive domains (such as executive function, attention, working memory, cognitive flexibility, and inhibitory control) and to examine potential differences across various exercise types.MethodA comprehensive search was conducted across multiple databases, including Web of Science, Embase, PubMed, the Cochrane Central Register of Controlled Trials, and CBM, to identify randomized controlled trials (RCTs) investigating the effects of physical exercise on cognitive function in adolescents. …”
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Thermal buckling of imperfect functionally graded cylindrical shells according to Wan-Donnell model by Hoang Van Tung, Nguyen Dinh Duc

“…A thermal buckling analysis of imperfect circular cylindrical shells of functionally graded material is considered. The material properties are assumed varying as a power form of thickness coordinate variable. …”
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Deciphering the comprehensive microbiome of glacier-fed Ganges and functional aspects: implications for one health by Rachel Samson, Shubham Kumar, Syed Dastager, Krishna Khairnar, Mahesh Dharne

“…The initial insights into the functional profile of the bacterial and phage diversity offer opportunities to explore various natural compounds and enzymes to tackle antimicrobial resistance under the one-health canopy.IMPORTANCEThis study addresses a knowledge gap by exploring the microbial diversity and antimicrobial potential of the glacier-fed Ganges River across different seasons. …”
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Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome by Jiao Sun, Jin-Young Kim, Semo Jun, Meeyeon Park, Ebbing de Jong, Jae-Woong Chang, Sze Cheng, Deliang Fan, Yue Chen, Timothy J. Griffin, Jung-Hee Lee, Ho Jin You, Wei Zhang, Jeongsik Yong

“…Furthermore, our investigation into the isoform-specific functions of JMJD6 intronic APA events supported the hypothesis that alterations in unstructured C-terminal protein regions lead to functional differences. …”
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Functional Elements of Entrusted Professional Activities for Dental Educators: Protocol for a Scoping Review by Noraini Abu Bakar, Nurhanis Syazni Roslan, Muhammad Ainul Haq, Yasmin Mustafa Byrnes, Muhamad Saiful Bahri Yusoff

“…This review seeks to answer the following research question: what are the key functional elements of EPAs for dental educators as described in the existing literature? …”
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Functional Connectivity Metrics in Temporal Lobe Epilepsy: A Machine Learning Perspective With MEG by M. V. Suhas, N. Mariyappa, A. Karunakar Kotegar, M. Ravindranadh Chowdary, K. Raghavendra, Ajay Asranna, L. G. Viswanathan, H. Anitha, Sanjib Sinha

“…Magnetoencephalography (MEG) offers a non-invasive method for evaluating brain function, providing detailed insights into TLE. In this study, we aim to evaluate the potential of functional connectivity metrics derived from MEG data at the source level for distinguishing TLE patients from healthy controls (HCs). …”
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A Functional-Pragmatic Evaluation Method for Translation Studies in the Context of Politness Theory and Facework by Neslihan Kansu-Yetkiner

“…The main emphasis is upon register analysis due its correlation with politeness and interpersonel language function. Our analyses show that the concept of face and politeness as part of pragmatic meaning in interpersonal relations is highly variable across both linguistic and cultural aspects. …”
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