Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders by Huizhen Liu, Ming Zhang, Minqi Chen, Liusi Chen, Tingrong Huang, Tingrong Huang, Zhao Ye, Zhao Ye

“…Concurrently, exercise has been shown to improve several indicators of heart function.MethodsA comprehensive search was conducted across seven databases. …”
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Large-scale examination of hot and cool executive function in children born preterm by Iris Menu, Mark Duffy, Tanya Bhatia, Sofia Trapaga, Jenna John, Selma Music, Daelah Nicholas, Seyeon Yim, Moriah E. Thomason

“…Preterm birth can significantly impact cognitive development, particularly executive functions (EF). This study investigated hot (with emotional/motivational aspects) and cool (purely neutral/cognitive) EF trajectories in preterm and full-term children, examining brain-behavior relationships. …”
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Functional areas shape indoor microbial structure and potential risks in university dormitories by Huaiyu Cao, Huaiyu Cao, Hanbing Ye, Yucheng Tian, Jinhong Zhang, Yongchao Xie, Yuan Chen, Qiuyue Mo, Song Huang, Yiqi Tao, Yiqi Tao, Yiqi Tao, Tang Liu

“…Environmental variations across room functional areas significantly influenced the composition profile of the microbiome, while the impact of occupant characteristics appeared negligible. …”
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Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue by Dorota Kaminska, Calvin Pan, Laurent Vergnes, Ashlyn Ro, Gurugowtham Ulaganathan, Aldons J. Lusis

“…Here, we tested whether iWAT contributes comparably to sex differences in mitochondrial function and futile cycling. Methods: We analyzed iWAT and gWAT from male and female mice across 58 genetically diverse Hybrid Mouse Diversity Panel (HMDP) strains fed a high-fat, high-sucrose diet. …”
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Optimization of Convolutional Neural Networks With Multi-Objective Function Metaheuristics for Melanoma Detection by Pamela Hermosilla, Ricardo Soto, Eric Monfroy, Emanuel Vega, Lucas Erazo, Valentina Guzman

“…Experimental results demonstrate that the proposed approach enhances model performance across key clinical metrics, obtaining a MOF score of 0.9032, with Accuracy, Recall, and AUC values of 0.9025, 0.9101 and 0.8925, respectively. …”
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Characterization and functional analysis of the BAM gene family in peanut (Arachis hypogaea L.) by Chaonan Shi, Peilin Li, Long Li, Long Li, Zhitao Qi, Tong Lu, Jinming Shi, Haodong Yang, Jin Wu, Jingyu Guo, Minghui Liu, Xiaozong Wu

“…These genes were unevenly distributed across 10 chromosomes, with chr05 and chr15 each containing three genes. …”
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Alterations in static and dynamic functional network connectivity in subcortical vascular cognitive impairment by Haixia Mao, Yachen Shi, Qianqian Gao, Min Xu, Xiaoyun Hu, Feng Wang, Xiangming Fang

“…Differences in dFNC temporal properties (fractional occupancy, mean dwell time, and number of transitions) and functional connectivity across different time domains between groups were assessed with two sample t-tests. …”
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Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice by Felix Sommer, Joana P. Bernardes, Lena Best, Nina Sommer, Jacob Hamm, Berith Messner, Víctor A. López-Agudelo, Antonella Fazio, Georgios Marinos, A. Samer Kadibalban, Go Ito, Maren Falk-Paulsen, Christoph Kaleta, Philip Rosenstiel

“…Abstract Background Alterations in the composition and function of the intestinal microbiota have been observed in organismal aging across a broad spectrum of animal phyla. …”
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Neurochemical and molecular characteristics of altered brain functional activity in the anti-NMDAR encephalitis by Xiarong Gong, Wei Li, Chengsi Luo, Yanghua Tian, Jiaojian Wang, Yuan Gao, Yuanyuan Guo, Meiling Chen, Qiang Meng

“…Results: Patients exhibited significant alterations in fALFF/ReHo across the frontal, temporal, and occipital cortices. …”
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Generation of Stochastic Daily Precipitation for China Based on Empirical Orthogonal Function Analysis by Yang Yifei, Fang Weihua, Zheng Jinli, Fu Jingxuan

“…Multiple probability distribution functions were used to fit the probability distributions of the mode coefficients for each day, with the optimal fitting function selected for each day. …”
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Review and Validation of Plant Gene Function Research Methods Bypassing Tissue Culture by Huanghuang Jiang, Suya Huang, Jiayi Wang, Deming Sun, Min Wang, Su Lin, Jinhua Liu, Kai Xu, Bei Liu, Haijie Ma

“…Here, we review the advances in plant genetic transformation research, performing analysis of three methods for plant gene function analysis that bypass tissue culture: <i>Agrobacterium rhizogenes</i>-mediated root genetic transformation, developmental regulators (DRs)-mediated genetic transformation, and virus-mediated genome editing. …”
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Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis by Tainã Luís de Souza, Tainã Luís de Souza, Marta de Almeida Santiago, Francini Neves Ribeiro, Francini Neves Ribeiro, Fabiano Borges Figueiredo, Artur Augusto Velho Mendes Junior, Rodrigo Caldas Menezes, Renato Porrozzi, Fernanda Nazaré Morgado

“…Dogs recognized as urban reservoir hosts, commonly harbor chronic infections characterized by elevated parasite burdens across multiple tissues. This study aims to analyze functional markers of M1 and M2 responses, as well as PD-L1+ macrophages in the spleens of naturally infected dogs with Leishmania infantum, and to correlate these findings with splenic white pulp disorganization, parasitic load, and clinical severity.MethodsThirty-four VL-infected dogs were enrolled, each undergoing clinical evaluation to determine a clinical severity score. …”
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Longitudinal graphics of patient-reported physical function in patients treated for hematologic malignancies by Gita Thanarajasingam, Vishal Bhatnagar, Brie N. Noble, Ting-Yu Chen, Mallorie H. Fiero, Ron Hoffman, Molly Jeffery, Gina L. Mazza, John Mascarenhas, Ruben Mesa, Meena Murugappan, Joseph Ross, Surbhi Sidana, Rahma Warsame, Paul G. Kluetz, Amylou C. Dueck

“…Abstract Background The US Food and Drug Administration (FDA) released a draft guidance document detailing core patient-reported outcomes in cancer clinical trials, including physical function (PF). The objectives of this study were to develop analytic methods and visualizations of patient-reported PF in patients with cancer. …”
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Environmental determinants of intraspecific variation in five functional traits of Pinus yunnanensis Franch by Xinrui Song, Ying Liu, Dongli Yu, Shuting Li, Wuchao Gao, Hong Zeng, Hong Zeng, Dongyu Cao, Dongyu Cao, Shixing Zhou, Shixing Zhou, Xinglei Cui, Xinglei Cui

“…However, the environmental drivers of intraspecific variation in its functional traits remain poorly understood. In this study, we examined the relationships between five functional traits (bark thickness, tree height, leaf dry matter content, leaf length, and specific leaf area) and habitat conditions across 20 populations, representing three varieties: var. yunnanensis (the original variety), var. pygmaea, and var. tenuifolia. …”
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Chronic intermittent fasting impairs β cell maturation and function in adolescent mice by Leonardo Matta, Peter Weber, Suheda Erener, Alina Walth-Hummel, Daniela Hass, Lea K. Bühler, Katarina Klepac, Julia Szendroedi, Joel Guerra, Maria Rohm, Michael Sterr, Heiko Lickert, Alexander Bartelt, Stephan Herzig

“…Here, we investigated the effects of IF on systemic metabolism and β cell function in old, middle-aged, and young mice. Short-term IF improves glucose homeostasis across all age groups without altering islet function and morphology. …”
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Functional characterization and therapeutic potential of human umbilical cord blood mononuclear cells by Yu Zhang, Yueda Lu, Xinyue Hu, Mengxing Jiang, Zhixiu Chen, Lingkun Jin, Min Li, Chen Chen, Jianye Wang

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Evolution of HD-ZIP transcription factors and their function in cabbage leafy head formation by Ju Zhang, Ju Zhang, Can Chen, Can Chen, Qihang Yang, Jie Xu, Zizhuo Han, Wei Ma, Xiaomeng Zhang, Kedong Xu, Jianjun Zhao, Xueping Chen

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Reconstructing coastal ponds functional classification: Integration of multi-feature remote sensing by Yijun Tong, Chen Lin, Ke Song, Tingchen Jiang, Ronghua Ma, Wenzhuo Cui, Danhua Ma, Jianchun Chen, Zhenxing Wang, Xiaofen Bai

“…Above all, the PWS classification system and data products developed in this study reveal the diverse relationships among “functional types-remote sensing features-geographical patterns” regarding PWS, implicating a crucial foundation for clarifying the ecological functional value of PWS and appropriate planning in the coastal zone.…”
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Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer by Sally E. Claridge, Shalini Nath, Anneliese Baum, Richard Farias, Julie‐Ann Cavallo, Nile M. Rizvi, Lamberto De Boni, Eric Park, Genesis Lara Granados, Matthew Hauesgen, Ruben Fernandez‐Rodriguez, Eda Nur Kozan, Evgeny Kanshin, Khoi Q. Huynh, Peng‐Jen Chen, Kenneth Wu, Beatrix Ueberheide, Juan Miguel Mosquera, Fred R. Hirsch, Robert J. DeVita, Olivier Elemento, Chantal Pauli, Zhen‐Qiang Pan, Benjamin D. Hopkins

“…Through the inclusion of emerging therapeutics in a high‐throughput drug screening platform, our functional genomics pipeline inverts the common paradigm to identify patient populations that are likely to benefit from novel therapeutic strategies. …”
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Enhancing regeneration and functionality of excitable tissues via integrating bioelectronics and bioengineered constructs by Zijie Meng, Bingsong Gu, Cong Yao, Jiaxin Li, Kun Yu, Yi Ding, Pei He, Nan Jiang, Dichen Li, Jiankang He

“…Additionally, the emergence of micro/nanoscale bioelectronics has significantly broadened this field, facilitating intimate interactions between implantable bioelectronics and excitable tissues across cellular, tissue, and organ levels. These interactions enable precise data acquisition and localized modulation of cell and tissue functionalities through intricately designed electronic components according to physiological needs. …”
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