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981
Massively parallel interrogation of human functional variants modulating cancer immunosurveillance
Published 2025-03-01“…We demonstrated that this mutation induces consistent phenotypic effects across multiple cancer cell lines and enhances the efficacy of immunotherapy in different tumor models. …”
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982
Structural Assessment of Flexible Pavements Based on the Level of Detail of Management Functions
Published 2025-04-01Get full text
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983
The taxonomic, functional and phylogenetic diversity of birds in Xiaohongxiang Wetland, southwest China
Published 2024-12-01“…While cherry plantations and pine forests enhance avian diversity near wetlands, their low functional diversity could limit the ecological niches available to birds. …”
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984
Multi-Function Evaluation and Internal Land Use Optimization of Rural Settlements
Published 2025-03-01“…Rural settlement is the main vehicle for the existence and development of the countryside. The functions of rural settlements vary across different regions, influencing land use patterns. …”
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985
Exploring the Functionality of Microbes in Fermented Foods: Technological Advancements and Future Directions
Published 2025-05-01“…This review explores microbial diversity and its role in the production of fermented foods across different regions of the world through a dynamic market analysis. …”
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986
Bridging regional neurovascular unit heterogeneity and cognitive function: a review
Published 2025-08-01“…The structural and functional differences of the endothelial cells, glial cells, and neurons of different brain structures are pinpointed. …”
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987
Involvement of Executive Functions in Idiom Comprehension: A Life-Span Perspective
Published 2024-10-01“…Objectives—Our aim is to investigate the executive functions involved in idiom comprehension. The understanding of idioms has largely been explored from a developmental perspective. …”
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988
The malaria secretome: from algorithms to essential function in blood stage infection.
Published 2008-06-01“…Attempted deletions of the genes encoding the conserved exported proteins were not successful, but additional functional analyses revealed the first conserved secretome function. …”
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989
Subgraphs of functional brain networks identify dynamical constraints of cognitive control.
Published 2018-07-01“…In this study, we use a quantitative approach to identify distinct topological motifs of functional interactions and examine how their expression relates to cognitive control processes and behavior. …”
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990
Functional characteristics and computational model of abundant hyperactive loci in the human genome
Published 2024-11-01“…Here, we used a set of 1003 TF ChIP-seq datasets (HepG2, K562, H1) to analyze the patterns of ChIP-seq peak co-occurrence in combination with functional genomics datasets. We identified 43,891 HOT loci forming at the promoter (53%) and enhancer (47%) regions. …”
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991
From Confirmation to Contention: Pragmatic Functions of 'Aywa' in Jordanian Spoken Arabic
Published 2025-04-01“…The study then categorized these functions, identifying recurrent patterns and situational uses of aywa across multiple interactional contexts. …”
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992
The emerging functions and clinical implications of circRNAs in acute myeloid leukaemia
Published 2025-04-01“…Circular RNAs (circRNAs) constitute a unique class of single-stranded RNAs featuring covalently closed loop structures that are ubiquitous across species. These molecules perform crucial regulatory functions in the pathogenesis of various diseases through diverse mechanisms, including acting as miRNA sponges, interacting with DNA or proteins, and encoding functional proteins/polypeptides. …”
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993
Surveying DNA Elements within Functional Genes of Heterocyst-Forming Cyanobacteria.
Published 2016-01-01“…The recombinase gene sequences served as genetic markers that were common across the interruption elements and were used to track element evolution. …”
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994
Functional and structural kidney alterations associated with fertility drug administration in rats
Published 2025-01-01“…This study aimed to evaluate renal changes in structure and function following infertility drug administration. …”
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995
Gender-affirming hormone therapy: effects on cardiovascular risk and vascular function
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996
Amino acid metabolism-mediated immune cell fate and function in pigs
Published 2025-01-01“…Therefore, this review focuses on the influence of amino acids on the fate and function of immune cells across development, homeostasis, activation, and effector phases, highlighting the underlying mechanisms. …”
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997
Assessment of Right Ventricle Function in Patients with Mitral Repair: Case Series
Published 2025-01-01“…Objectives: We aim to assess right ventricular function in patients undergoing mitral valve repair using trans-esophageal echocardiography, focusing on the predictive value of right ventricular longitudinal strain compared to other echocardiographic measures. …”
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998
Profiling Cognitive and Social Functioning in a Small Cohort with Malan Syndrome
Published 2025-01-01“…<b>Conclusions</b>: These findings provide a further characterisation of cognitive and social functioning in MALNS, which can inform future research as well as clinical practice and rehabilitation…”
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999
Brain Functional Connectivity During First- and Third-Person Visual Imagery
Published 2025-04-01“…Despite the frequent use of perspective switching across various contexts, including modern media and in therapeutic settings, the neural mechanisms differentiating these two perspectives in visual imagery remain largely underexplored. …”
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1000
An Optimization Method for Multi-Functional Radar Network Deployment in Complex Regions
Published 2025-02-01“…This paper addresses the deployment of a multi-functional radar network (MFRN) in complex regions that may exhibit non-connectivity, holes, or concave shapes, utilizing multi-objective particle swarm optimization (MOPSO). …”
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