Application of Levi’s Muscle Index in frailty assessment: comparison of bioimpedance measures among older adults by Kworweinski Lafontant, Kworweinski Lafontant, David H. Fukuda, Estefania Zamarripa, Estefania Zamarripa, Abigail L. Tice, Jethro Raphael M. Suarez, Jethro Raphael M. Suarez, Chitra Banarjee, Chitra Banarjee, Dahee Kim, Jeffrey R. Stout, Jeffrey R. Stout, Joon-Hyuk Park, Joon-Hyuk Park, Rui Xie, Rui Xie, Rui Xie, Ladda Thiamwong, Ladda Thiamwong

“…IntroductionFrailty is prevalent among older adults and is characterized by reductions in physical function and muscle quality. Despite the emerging clinical utility of bioelectrical impedance analysis (BIA) and phase angle (PhA) as a bioimpedance index, little is known about how bioimpedance indices such as Levi’s Muscle Index (LMI), reactance/height (Xc/Height), and resistance/height (R/Height), relate to physical function and frailty.MethodsThis cross-sectional study examined 208 community-dwelling older adults (female, n = 183; age = 74.2 ± 6.9 years; BMI = 30.4 ± 6.4 kg/m2) to compare physical function measures and bioimpedance indices across frailty categories determined by the FRAIL questionnaire. …”
Get full text

The evolution of three-dimensional knee kinematics after ACL reconstruction within one year by Lingchuang Kong, Huahao Lai, Xiaolong Zeng, Peng Gao, Peng Gao, Wenhao Liang, Qi Gao, Qi Gao, Zhiyuan Kong, Wu Wu, Xiaona Wu, Tao Zhang

“…The recovery rates and patterns differ significantly across dimensions, with some abnormalities not fully corrected within one-year post-urgery. …”
Get full text

Efficacy of Laparoscopic versus Open Donor Nephrectomy in the Living Kidney Donor: A Retrospective Cohort Study by Sashikant Asabe, Shivam Singh, Sunil Mhaske, Vilas P Sabale

“…Secondary outcomes included length of hospital stay, postoperative pain, recipient graft function, and donor renal function at the time of discharge. …”
Get full text

Digital Behavior Change Interventions to Promote Physical Activity and Reduce Sedentary Behavior Among Survivors of Breast Cancer: Systematic Review and Meta-Analysis of Randomized... by Xiaoyan Zhang, Jiaxin Fang, Yufang Hao, Dan Yang, Jiayin Luo, Xin Li

“…Meta-analysis revealed that DBCIs significantly improved shoulder range of motion across all planes (flexion: standardized mean difference [SMD]=2.08, 95% CI 1.14-3.01; P<.001; extension: SMD=1.74, 95% CI 0.79-2.70; P<.001; abduction: SMD=2.32, 95% CI 1.35-3.28; P<.001; external rotation: SMD=2.29, 95% CI 0.96-3.62; P<.001; internal rotation: SMD=2.98, 95% CI 1.08-4.87; P=.002; adduction: SMD=2.09, 95% CI 1.16-3.02; P<.001), finger climbing wall height (SMD=1.65, 95% CI 1.35-1.95; P<.001), upper-extremity function (SMD=−0.96, 95% CI −1.50 to −0.42; P<.001), quality of life (SMD=1.83, 95% CI 0.44-3.22; P=.01), and reduced pain (SMD=−0.58, 95% CI −0.93 to −0.22; P=.002). …”
Get full text

Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial by Queralt Asla, Maite Garrido, Eulàlia Urgell, Sílvia Terzan, Alicia Santos, Mercè Fernández, Nimmy Varghese, Cihan Atila, Anna Calabrese, Betina Biagetti, Franziska Plessow, Ignasi Gich, Mirjam Christ-Crain, Anne Eckert, Susan M. Webb, Elizabeth A. Lawson, Anna Aulinas

“…CRH administration did not impact oxytocin concentrations across groups over time (p = 0.97). HHD had greater psychopathology (most ps < 0.05), sexual dysfunction (p < 0.03) and worse QoL (p < 0.001) compared to HC, nevertheless, baseline oxytocin concentrations and area under the curve of oxytocin were not significantly associated with psychopathology, sexual function or QoL, neither in HHD or HC. …”
Get full text

Hormones, Age, and Erectile Dysfunction: Should Routine Testing Be Part of the Initial Evaluation? by Daniel Porav-Hodade, Raul Dumitru Gherasim, Irina Bianca Kosovski, Toader Septimiu Voidazan, Nicolae Crisan, Petrut Bogdan, Radu Galis, Bogdan Ovidiu Feciche, Mártha Orsolya Katalin Ilona, Ciprian Todea-Moga

“…Total testosterone levels progressively decreased with the increase in the severity of erectile dysfunction, from a median of 7.05 ng/mL in patients with normal erectile function to 3.56 ng/mL in those with severe symptoms, remaining above the normal minimum threshold across all groups, whereas free testosterone (FT) levels also declined progressively. …”
Get full text

Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments by Erin Hodgson, Erin Hodgson, Erin Hodgson, Erin Hodgson, Elizabeth G. Condliffe, Elizabeth G. Condliffe, Elizabeth G. Condliffe, Elizabeth G. Condliffe, Elizabeth G. Condliffe, Leigh Gabel, Leigh Gabel, Leigh Gabel, Leigh Gabel

“…ObjectivesThis study quantified bone and muscle health in children and adolescents with CP and other neuromotor impairments across all five gross motor function classification system (GMFCS) levels.MethodsPeripheral quantitative computed tomography (pQCT) scans of both tibiae were acquired at the 3%, 38%, and 66% of tibia length in 22 children and adolescents (4–17 years old) diagnosed with CP and “CP-like” neurodevelopmental conditions causing motor impairment. …”
Get full text

Factors associated with head circumference and indices of cognitive development in early childhood by Matthew R Grigsby, William Checkley, Tahmeed Ahmed, Zulfiqar Ahmed Bhutta, Laura Nicolaou, Pascal Bessong, Margaret Kosek, Aldo A M Lima, Sanjaya Shrestha, Ram Chandyo, Estomih R Mduma, Laura Murray-Kolb, Brooks Morgan

“…Background While head circumference (HC) has been related to intracranial volume and brain size, its association with cognitive function remains unclear. We sought to understand the relationship among various biological and socioeconomic risk factors, HC and cognitive development.Methods We analysed data across resource-poor settings in Bangladesh, India, Nepal, Peru, South Africa and Tanzania from the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development longitudinal birth cohort study. …”
Get full text

The effectiveness of the Halliwick concept hydrotherapy and Bobath (Neurodevelopmental Treatment-NDT) in the treatment of children with cerebral palsy–A randomised controlled trial... by Konstantinos Chandolias, Eleni Argyroula Tsounia, Nikolaos Strimpakos, Efthalia Zogka, Thomas Besios, Georgios Marios Kyriakatis, Panagiotis Tsimeas, Athanasios Tsiokanos

“…Results: Statistically significant improvements were observed in the intervention group when compared with control groups across all measures. The intervention group demonstrated greater gains in gross motor function, balance, daily activities, and speed, using the TUG test, compared to control group 1, with minimal changes observed in control group 2. …”
Get full text

Joint Resource Allocation for V2X Sensing and Communication Based on MADDPG by Zhiyong Zhong, Zhangyou Peng

“…In addition, a reward function is designed based on the characteristics of the scenario. …”
Get full text

Spatial dependencies between large-scale brain networks. by Robert Leech, Gregory Scott, Robin Carhart-Harris, Federico Turkheimer, Simon D Taylor-Robinson, David J Sharp

“…Functional neuroimaging reveals both increases (task-positive) and decreases (task-negative) in neural activation with many tasks. …”
Get full text

Gamma synchronization between the medial temporal lobe and medial frontal cortex for goal-directed visual attention in humans by Jie Zhang, Jing Xia, Huihui Zhou, Shuo Wang

“…Summary: Goal-directed visual attention is a fundamental cognitive function that engages multiple brain regions, yet the neural circuit mechanisms in humans remain unclear. …”
Get full text

Predicting Affinity Through Homology (PATH): Interpretable binding affinity prediction with persistent homology. by Yuxi Long, Bruce R Donald

“…Based on insights from PATH+, we built PATH-, a scoring function for differentiating between binders and non-binders that has outstanding accuracy against 11 current algorithms for BAP. …”
Get full text

Impact of Droplet Splashing on Biological and Medical Materials Relevant to Clinical Settings by Mohammad Hadi Esteki, Ian Eames, Emad Moeendarbary

“…., bone, meat, eye, skin, hair, nail, and tooth) and medical surfaces across a range of droplet velocities are comparatively analyzed. …”
Get full text

Parameterization of the Differences in Neural Oscillations Recorded by Wearable Magnetoencephalography for Chinese Semantic Cognition by Xiaoyu Liang, Huanqi Wu, Yuyu Ma, Changzeng Liu, Xiaolin Ning

“…Neural oscillations observed during semantic processing embody the function of brain language processing. Precise parameterization of the differences in these oscillations across various semantics from a time–frequency perspective is pivotal for elucidating the mechanisms of brain language processing. …”
Get full text

An Engineering Approximation on the Transformation of Plastic Work into Heat at Various Strain Rates and Stress States by Li Xueyang, Roth Christian C., Grolleau Vincent, Mohr Dirk

“…This study investigates DP800 sheet metal specimens across nine strain rates (0.001/s to 150/s) using notched tension (NT) and shear (SH) specimens to explore stress-state effects. …”
Get full text

High resolution satellite imaging 0.5U-size freeform telescope for CubeSat by Jacek Wojtanowski

“…It is diffraction limited across the whole (3o) field of view.DiscussionFreeform optics design technology was successfully applied to design a miniature space telescope. …”
Get full text

Glial Diversity and Evolution: Insights from Teleost Fish by Carla Lucini, Claudia Gatta

“…Glial cells, once considered mere support for neurons, have emerged as key players in brain function across vertebrates. The historical study of glia dates to the 19th century with the identification of ependymal cells and astrocytes, followed by the discovery of oligodendrocytes and microglia. …”
Get full text

Otx2 mRNA expression is downregulated following traumatic brain injury in zebra finches by Adam Talwalkar, Kelli A. Duncan

“…The transcription factor Otx2 is critical for early brain and sensory organ development, as well as the maintenance of retinal and neural function in adulthood. Notably, the transfer of Otx2 homeoprotein into parvalbumin-expressing (PV+) GABAergic interneurons is essential for opening and closing critical periods of plasticity across vertebrates. …”
Get full text

Excitatory-inhibitory homeostasis and bifurcation control in the Wilson-Cowan model of cortical dynamics. by Francisco Páscoa Dos Santos, Paul F M J Verschure

“…Our findings tie relevant features of cortical networks, such as E-I balance, the generation of gamma oscillations, and edge-of-bifurcation dynamics, under the framework of firing-rate homeostasis, providing a mechanistic explanation for the heterogeneity in the distance to the bifurcation found across cortical areas. In addition, we reveal the functional benefits of relying upon different homeostatic mechanisms, providing a robust method to regulate network dynamics with minimal perturbation to the generation of gamma rhythms and explaining the correlation between inhibition and gamma frequencies found in cortical networks.…”
Get full text