Activity-based costing for HIV, primary care and nutrition services in low- and middle-income countries: A systematic literature review and synthesis by Diana Bowser, Anna Sombrio, Neto Coulibaly, Noah Mark

“…The largest unit cost across nutrition services was training (US$194.16 per patient, 34.6% of total unit cost). …”
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Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks by Wende Chen, Shaojie Han, Rong Li, Shuo Li, Zhi Cao, Qing Pan, Gen Li

“…In contrast, NDRV infection led to consistent downregulation of duPTEN across all three tissues.DiscussionThis study is the first to characterize the molecular cloning, tissue-specific expression, and virus-induced regulation of duPTEN in ducks. …”
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A Novel Optimized Silver Nitrate Staining Method for Visualizing and Quantifying the Osteocyte Lacuno-Canalicular System (LCS) by Jinlian Wu, Chunchun Xue, Qiang Li, Hongjin Wu, Jie Zhang, Chenglong Wang, Weiwei Dai, Libo Wang

“…It will significantly advance research in osteocyte biology and provide a valuable tool for exploring the adaptive evolution of osteocyte LCS morphology and function across various taxa.…”
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Breathlessness dimensions association with physical and mental quality of life: the population based VASCOL study of elderly men by Jacob Sandberg, David Currow, Magnus Ekström, Miriam Johnson, Max Olsson, Lucas Cristea

“…Scores were compared as z-scores across scales and analysed using multivariable linear regression, adjusted for smoking, body mass index and the presence of respiratory and cardiovascular disease.Results Worse breathlessness was related to worse physical and mental QoL across all the D-12 and MDP dimension scores. …”
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Transcriptomic profiling of immune modulation induced by vitamin D3 in the VitDPAS and VitDHiD cohort studies by Emilia Gospodarska, Ranjini Ghosh Dastidar, Julia Jaroslawska, Maciej Rybiński, Marianna Raczyk, Kornelia Tokarczyk-Malesa, Jerzy Romaszko, Carsten Carlberg

“…A comparative analysis with the VitDHiD study (NCT03537027), conducted on a Finnish cohort of 25 healthy participants, revealed 232 overlapping target genes, enabling an integrated assessment of vitamin D responsiveness across all 70 individuals. Applying a more stringent statistical threshold (false discovery rate < 0.05) highlighted 26 shared target genes, demonstrating a consistent in vivo response to vitamin D3 across both cohorts. …”
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The role of SLC2A1 in lung adenocarcinoma: From tumorigenesis to patient survival. by Zijun Xiao, Qinqin Long, Jiaxing Liao, Fengdie Huang, Lusheng Liao, Mingyou Dong

“…Furthermore, we sought to determine the SLC2A1 function in LUAD initiation and progression through in vivo and in vitro experiments.…”
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Substitution of Fishmeal With Soy Protein Concentrate on Growth, Organic Damage, Antioxidant, Transcriptome, and Metabolomics in Macrobrachium rosenbergii by Li Wang, Qincheng Huang, Zhimin Gu, Cui Liu, Jia Xu, Yangxin Dai, Tiantian Ye, Junjun Yan, Jilun Meng, Yutong Zheng, Bo Liu

“…Based on the transcriptomics, two differentially expressed genes (DEGs) LOC136825138 and LOC136856310 were consistently observed across all groups. The metabolomics indicated that 77 differentially expressed metabolites (DEMs) across all treatments. …”
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Insights from the European Nontuberculous mycobacterial pulmonary disease PAtient Disease Experience (ENPADE) survey– exploring disease burden and impact by Michal Shteinberg, Marko Obradovic, Roald van der Laan, Christian Hoenig, Roger J. Legtenberg, Andreas L. G. Reimann, Natalie Lorent

“…NTM-PD can severely impair lung function and quality of life, potentially leading to both increased healthcare costs and mortality. …”
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Trans-kingdom conservation of mechanism between bacterial actifensin and eukaryotic defensins by Ivan Sugrue, Carolin Ade, Paula M. O’Connor, Jan-Martin Daniel, Paolo Innocenti, Nico Kirsch, Nathaniel I. Martin, Günther Weindl, Colin Hill, Tanja Schneider, R. Paul Ross

“…These findings emphasise the conserved structure-function relationship of antimicrobials across kingdoms, suggesting a shared evolutionary history of defensins and highlight the therapeutic potential for them or their variants.…”
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Molecular mechanism of androgen receptor mutation in multigenerational mild androgen insensitivity syndrome by Ravind Pandher, Ruby Chang, Yiqun Chang, David E Hibbs, Jonathan J Du, Kristine McGrath, Alison Heather, Veena Jayadev, David J Handelsman

“…Clinical features and responses to high-dose testosterone treatment of three cases of MAIS across a six-generation family pedigree are described. …”
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Characteristics of folic acid metabolism-related genes unveil prognosis and treatment strategy in lung adenocarcinoma by Yanting Dong, Xiaoyan Wang, Chuanchuan Dong, Peiqi Li, Zhuola Liu, Xinrui Tian

“…Clinical correlations and enrichment analyses were carried out to explore the functions of DEGs and their associations with clinical characteristics of LUAD patients. …”
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Virtual stressors with real impact: what virtual reality-based biobehavioral research can teach us about typical and atypical stress responsivity by Elizabeth A. Shirtcliff, Tor T. Finseth, Eliot H. Winer, David C. Glahn, Roselynn A. Conrady, Stacy S. Drury

“…Abstract Stress contributes to transdiagnostic morbidity and mortality across a wide range of physical and mental health problems. …”
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Foreword

“…The paper categorizes cognitive and mnemonic approaches across learning stages and genders, highlighting a critical disconnect between strategy frequency and perceived effectiveness. …”
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Comparison of the within-reader and inter-vendor agreement of left ventricular circumferential strains and volume indices derived from cardiovascular magnetic resonance imaging. by Doyin S Mansell, Evelyn G Frank, Nathaniel S Kelly, Bruno Agostinho-Hernandez, James Fletcher, Vito D Bruno, Eva Sammut, Amedeo Chiribiri, Thomas Johnson, Raimondo Ascione, Jonathan W Bartlett, Harinderjit S Gill, Katharine H Fraser, Andrew N Cookson

“…<h4>Purpose</h4>Volume indices and left ventricular ejection fraction (LVEF) are routinely used to assess cardiac function. Ventricular strain values may provide additional diagnostic information, but their reproducibility is unclear. …”
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A novel multi-timescale comprehensive drought index for drought monitoring in the Xijiang River Basin by Liping Wang, Shufang Wang, Jing Li, Xingnan Zhang

“…This study provides theoretical support for improving drought monitoring across multiple drought types.…”
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Detection of slow slip event lasting several months in the shallow region of the Suruga Trough, the eastern end of the Nankai Trough, Japan by Yuji Kikuchi, Yuta Mitsui, Masayuki Kano

“…This result was consistent across all three assumed plate interface models. Furthermore, slip extending to the trench was also inferred. …”
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Exploring neurofilament light chain as a biomarker for kidney disease: insights, implications, and future directions by Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Chinonyelum Emmanuel Agbo, Ikponmwosa Jude Ogieuhi, Ibukunoluwa Victoria Ishola, Victor Oluwatomiwa Ajekiigbe, Oluwaseun Oyewo, Badrudeen Olalekan Alabi, Jonathan Oluwafemi Adeola, David Opeyemi Olaewe, Adetola Emmanuel Babalola

“…Abstract Background Neurofilament light chain (NfL) has emerged as a sensitive biomarker for neuronal injury across various neurological disorders. Recent studies suggest that its elevated serum levels are also associated with kidney disease, including chronic kidney disease, acute kidney injury, and diabetic nephropathy. …”
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Token-Mol 1.0: tokenized drug design with large language models by Jike Wang, Rui Qin, Mingyang Wang, Meijing Fang, Yangyang Zhang, Yuchen Zhu, Qun Su, Qiaolin Gou, Chao Shen, Odin Zhang, Zhenxing Wu, Dejun Jiang, Xujun Zhang, Huifeng Zhao, Jingxuan Ge, Zhourui Wu, Yu Kang, Chang-Yu Hsieh, Tingjun Hou

“…Built on a transformer decoder and trained with causal masking, Token-Mol introduces a Gaussian cross-entropy loss function tailored for regression tasks, enabling superior performance across multiple downstream applications. …”
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Health-related quality of life after prosthodontic rehabilitation in patients with COVID-19-associated mucormycosis: A systematic review by Gunjan Chouksey, Rupali Choure, Kritika Singhal

“…Health-related quality of life (HRQOL) measures an individual’s ability to function optimally in various aspects of life and their subjective sense of well-being across the physical, mental, and social dimensions of health. …”
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Antenna systems for IoT applications: a review by Sunawar Khan, Tehseen Mazhar, Tariq Shahzad, Afsha Bibi, Wasim Ahmad, Muhammad Amir Khan, Mamoon M. Saeed, Habib Hamam

“…This research tackles these key elements to enable the next generation of antenna systems to meet IoT technology's expanding needs and increase networked devices' functionality, efficiency, and integration across industries. …”
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