Evaluating Neurotherapeutic Potential of Naringenin by True Experiments: Insights into In-Vivo Psychiatry Care Models by Abdul Ghafoor, Sana Kashif, Syed Muhammad Shahkar Ali, Samreen Memon, Shaheer Suhail Memon, Asim Mehmood, Pirya Nangdev

“… Background:  The brain function and development are impaired when psychiatric disorders cause neuroinflammation and neurotrophic dysregulation. …”
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Insulin Modulates NK Cell Activity in Liver Fibrosis MASH Patients via the STING Pathway by Johnny Amer, Ahmad Salhab, Amiram Ariel, Rifaat Safadi

“…In contrast, NK cells from early fibrosis (F1/F2) exhibited higher STING expression and better functional activity. STING agonist treatment (2′3′-cGAMP) restored STING expression and enhanced NK cell activity across all fibrosis stages. …”
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Comparison of Clinical Characteristics and Prognosis Among Spontaneous Pneumothorax Patients of Different Ages: A Two-Year Follow-Up Study by Wang T, Bai Y

“…In this study, patients with SP across various age groups were enrolled, and their clinical features and prognoses were compared.Patients and Methods: The patients were divided into three groups: neonates (n=52), adolescents/adults (n=76), and elderly (n=70). …”
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Efficacy of suspension exercise training in spinal cord injury: a systematic review and meta-analysis by Yuntao Li, Minmin Wu, Jiguang Pan, Luwen Zhu

“…Methods The authors conducted a comprehensive search across eight databases to identify all relevant randomized controlled trials (RCTs) on October 20, 2024. …”
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Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions by Yuan Gao, Yanyan Liu, Tingting Ma, Qimeng Liang, Junqi Sun, Xiaomeng Wu, Yinglong Song, Hui Nie, Jun Huang, Guangqing Mu

“…Clinical evidence supports significant improvements in metabolic parameters (fasting glucose, lipid profiles, blood pressure) and reductions in systemic inflammation across metabolic syndrome, hypertension, and IBS cohorts. …”
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Effect of repeated controlled ovarian stimulation on pregnancy outcomes in fresh embryo transfer cycles: a retrospective cohort study by Shiming Wang, Xiaoli Chen, Ningning Wang, Yingchun Su, Lin Qi

“…Conclusion(s) The number of COS cycles did not significantly adversely affect pregnancy outcomes across different populations. In self-controlled comparisons within the same population, repeated COS (≤ 5 cycles) may not impair ovarian reserve function, while repeated COS (≤ 4 cycles) positively influenced clinical pregnancy outcomes, suggesting a potential cumulative effect. …”
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The role of the human cerebellum in representing social behavior sequences: An SDM-PSI meta-analysis by Yuting Zhang, Yidan Qiu, Shuting Lin, Xiaoyu Zheng, Liwei Tan, Xia Liu, Ruiwang Huang

“…However, little is known about (1) whether explicit sequencing processes elicit stronger cerebellar activation than non-sequencing processes, (2) whether the cerebellar sequence detection function is more applicable to social or non-social contexts, or (3) whether the cerebellum exhibits consistent or heterogeneous activation patterns in representing behavioral sequences across contexts. …”
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The effects of multi-day rTMS and cardiorespiratory fitness on working memory and local GABA concentration by Joshua Hendrikse, Sarah Thompson, Chao Suo, Murat Yücel, Nigel C. Rogasch, James P. Coxon

“…Instead, we report some evidence of improved WM function following the first week of pre-SMA rTMS stimulation, and a generalised increase in GABA concentration across both parietal and pre-SMA voxels following pre-SMA rTMS. …”
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Aspirin is associated with a reduction in mortality rate for patients with sepsis-induced coagulopathy: a retrospective cohort study by Dan Xu, Dan Xu, Jingyuan Li, Zhiyuan Wang, Junda Li, Qingyu Zhao, Qiannan Zhao, Fei Xie, Tingting Li, Jiying Chen, Xiya Wang, Xin Zhou, Yuan Guo, Shuxing Wei

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Longitudinal Analysis of Stroke Patients’ Brain Rhythms during an Intervention with a Brain-Computer Interface by Ruben I. Carino-Escobar, Paul Carrillo-Mora, Raquel Valdés-Cristerna, Marlene A. Rodriguez-Barragan, Claudia Hernandez-Arenas, Jimena Quinzaños-Fresnedo, Marlene A. Galicia-Alvarado, Jessica Cantillo-Negrete

“…More EEG channels presented significant ERD/ERS trends across sessions related with time since stroke onset, in beta, compared to alpha. …”
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Upper Elevational Limit of Vegetation in the Himalayas Identified from Landsat Images by Bo Wei, Yili Zhang, Linshan Liu, Binghua Zhang, Dianqing Gong, Changjun Gu, Lanhui Li, Basanta Paudel

“…Subsequently, the Canny edge detection algorithm was applied to identify vegetation edge pixels, and elevation differences were utilized to determine the upper edges of the vegetation. Finally, Gaussian function-based thresholds were used across 24 sub-basins to determine the vegetation lines. …”
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Comparing methods for glomerular filtration rate estimation by Xiaoqian Zhu, Tariq Shafi, Keith C. Norris, Jeannette Simino, Srishti Shrestha, Thomas H. Mosley, Michael E. Griswold, Seth T. Lirette

“… Abstract Background: The glomerular filtration rate (GFR), estimated from serum creatinine (SCr), is widely used in clinical practice for kidney function assessment, but SCr-based equations are limited by non-GFR determinants and may introduce inaccuracies across racial groups. …”
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Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis by Yanyan Zhu, Yike Gao, Xiaoqing Huang, Bowang Chen, Bowang Chen, Xinyi Wang, Ying Wu, Jian Sun, Xiaoyun Huang, Xiaoyun Huang

“…Understanding TRA16’s involvement in cancer biology could uncover novel regulatory mechanisms and potential therapeutic targets.MethodsWe conducted a comprehensive pan-cancer analysis of TRA16 expression and function across multiple human malignancies. Gene co-expression networks, pathway enrichment, transcription factor analysis, organoid modeling, and intercellular communication profiling were employed. …”
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Acute Effects of Different Alcohol Doses on Psychomotor Performance and Subjective Responses among Healthy Young Women in China by Xiaoqin Yi, Li Xiao, Jin Xiang, Weihao Fan, Yingqiang Fu, Linchuan Liao, Yi Ye

“…Moreover, BAES scores for excitement and inhibition remained consistent across different alcohol doses compared to predrinking levels. …”
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Proteomic Analysis of Protein Ubiquitination Events in Dairy Goats with Fatty Liver by Yuli Zhu, Zhenhua Liu, Yuming Zhang, Yao Meng, Xunuo Song, Jinyu Li, Yue Zhang, Junkang Zhao, Liyin Du, Qinghua Deng

“…Among them, ubiquitination was upregulated at 351 sites across 93 proteins and downregulated at 570 sites across 145 proteins. …”
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Genotype × environment interaction analysis and climatic factors impacts on grain yield in rainfed durum wheat trials in Iran by Reza Mohammadi, Moslem Abdipour, Mahnaz Rahmati, Mohammad Armion, Nastaran Mehri, Asghar Mehraban

“…The GGE biplot’s “which-won-where” function identified breeding lines G17, G24, G14, and G19 as top performers under drought conditions. …”
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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…Abstract Nuclear clearance and cytoplasmic aggregation of TDP-43, initially identified in ALS-FTD, are hallmark pathological features observed across a spectrum of neurodegenerative diseases. We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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A chronosequence of climosequences: The evolution of ecological soil thresholds in Hawaiian volcanic soils by Thomas P. Haensel, Jesse Bloom Bateman, Tai McClellan Maaz, Jonathan L. Deenik, Noa K. Lincoln

“…We quantified thresholds delineating the exhaustion of primary minerals on all eight substrates and thresholds indicating the mobilization of iron on the three oldest soil substrates. Across the chronosequence, thresholds in surface soils shifted to drier climates (i.e., lower water balance values) as soil substrate age increased, following a highly predictable (R2 = 0.94) logarithmic decay function, with rapid evolution occurring in young soils and deceleration of change occurring in older soils. …”
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Pan-cancer analysis and validation show GTF2E2's diagnostic, prognostic, and immunological roles in regulating ferroptosis in endometrial cancer. by Nie Zhang, Xuejin Qin, Jingjing Liu, Ke Han, Manman Kang, Zhengchun Zhu, Di Zhang, Fei Zhong

“…Employing a multi-pronged approach with tools including R, Cytoscape, TISIDB, cBioPortal, STRING, GSCALite, and CancerSEA, we investigated GTF2E2's expression patterns, prognostic value, mutational landscape, functional enrichment, and immunological associations across 33 cancer types. …”
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Mt or not Mt: Temporal variation in detection probability in spatial capture-recapture and occupancy models by Sollmann, Rahel

“…Ignoring temporal variation allows collapsing detection data across repeated sampling occasions, speeding up computations, which can be important when analyzing large datasets with complex models. …”
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